Clinical trials: Physiological Conditions, open to volunteers
Infant, Premature, Diseases, Premature Birth of Newborn
Elevated Midline Positioning During Diaper Change in Preterm Infants
Diaper changing is one of the most frequent routine care procedures in the neonatal intensive care unit (NICU) and is known to cause physiological instability and behavioral stress responses in preterm infants.
- Conditions
- Infant, Premature, Diseases, Premature Birth of Newborn, Pain
- Trial name
- NCT07865897
- Testing
- 30-Degree Elevated Midline Positioning, Standard Lateral Position Diaper Change
- Volunteers
- 80 people
- Sponsor
- Akdeniz University
Liver Cirrhosis, Gastrointestinal Bleeding
Utilizing of Physiological Parameters Predict the Prognosis of Cirrhotic Patients With Gastrointestinal Bleeding
Can physiological indicators such as quick Sequential Organ Failure Assessment , Shock Index, and its derived indicators such as Modified Shock Index , Age Shock Index and Respiratory Adjusted Shock Index accurately predict the…
- Trial name
- SI (NCT06680583)
- Testing
- physical indicators such as shock index relatives
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- St. Martin De Porress Hospital
Tracheostomy, Care
The Effects of Listening to Fairy Tales, Listening to Fairy Tales in Their Mothers' Voices, and Watching Cartoons on Pain, Comfort Levels, and Physiological Parameters During Tracheostomy Care in a Palliative Care Clinic
This study aimed to determine the effects of listening to fairy tales, listening to fairy tales from the mother's voice, and watching cartoons on pain, comfort, and physiological parameters during tracheostomy care of children…
- Trial name
- NCT07210346
- Testing
- fairy tales, mother's voice, Cartoons
- Where
- Turkey (Türkiye)
- Volunteers
- 17 people
- Sponsor
- Ataturk University
Male Erectile Disorder, Prostate Cancer
Focal Therapy for Prostate Cancer Using HIFU
RATIONALE: Prospective trials using hemi-ablation with high intensity focused ultrasound (HIFU) (Sonablate 500) have demonstrated feasibility, safety, and encouraging functional outcomes and early cancer control with 90% of men…
- Conditions
- Male Erectile Disorder, Prostate Cancer, Therapy-related Toxicity, Urinary Incontinence
- Trial name
- INDEX (NCT01194648)
- Testing
- questionnaire administration, assessment of therapy complications, high-intensity focused ultrasound ablation
- Where
- United Kingdom
- Volunteers
- 354 people
- Sponsor
- University College, London
Newborn Care, Pain Management
The Effect of Breast Milk, 10% and 20% Dextrose on Pain and Physiological Variables During Heel Puncture in Infants
Pain, defined by the International Association for the Study of Pain as a subjective, sensory, and emotional experience, differs from nociception, which is merely a neural activity.
- Conditions
- Newborn Care, Pain Management, Physiological Parameters During Newborn Care İn Newborn's, Breast Milk
- Trial name
- NCT07716813
- Testing
- Administering oral breast milk in a supportive position, Administering oral 10% dextrose in a supportive position, Administering oral 20% dextrose in a supportive position
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Mersin University
Respiratory Mechanics, Monitoring, Physiologic
Dynamic Non-invasive Monitoring of Inspiratory Effort
This prospective, observational cohort study aims to evaluate whether the dynamic monitoring of a patient's breathing effort can predict successful liberation from invasive mechanical ventilation.
- Conditions
- Respiratory Mechanics, Monitoring, Physiologic, Respiratory Insufficiency Requiring Mechanical Ventilation, Critical Illness
- Trial name
- NCT07839949
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Children's Anxiety Levels, Children's Behavior
The Effect of Vibration Devices on Pain and Discomfort During Local Anesthesia Administration in Children
This split-mouth randomized clinical trial will be conducted at the Department of Pediatric Dentistry, King Abdulaziz University Dental Hospital (KAAUDH).
- Conditions
- Children's Anxiety Levels, Children's Behavior, Physiological Changes (Heart Rate), Obejective Pain and Discomfort
- Trial name
- NCT07384923
- Testing
- DentalVibe intraoral vibration device, Buzzy Bee® extraoral vibration device
- Where
- Saudi Arabia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Exercise, Fatigue
Physiological Responses to Basketball-Specific Interval Exercise in Female Basketball Players
This study aims to evaluate the effects of interval exercise on metabolic and inflammatory responses, energy substrate utilization, and fatigue in trained female basketball players.
- Conditions
- Exercise, Fatigue, Sport Physiology
- Trial name
- INTER-BASKET (NCT07752459)
- Testing
- Yo-Yo Intermittent Recovery Test Level 1 (Yo-Yo IR1)
- Where
- Poland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Pain, Sedation
Effect of Maternal Voice on Pain, Sedation, and Physiological Parameters in Mechanically Ventilated Children
Children in the pediatric intensive care unit often experience pain and stress from medical procedures, even while sedated. This study will test whether playing a recording of the child's mother's voice helps reduce pain and the…
- Conditions
- Pain, Sedation, Mechanical Ventilation
- Trial name
- NCT07753486
- Testing
- Recorded Maternal Voice
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- TC Erciyes University
Neurofibromatosis Type 1
A Study to Evaluate the Feasibility of a Physiologic Biomarker to Assess Pain and Other Sensory Problems Using Pupillometry in Participants With Neurofibromatosis Type 1 (NF1)
Background: Neurofibromatosis type 1 (NF1) is a genetic condition that causes tumors to grow along the nerves in the skin, brain, and other parts of the body.
- Trial name
- NCT06507748
- Testing
- AlgometRx Nociometer(R)
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- National Cancer Institute (NCI)
Obesity, Adolescent Obesity
Physiologic Response to Bariatric Surgery and the Impact of Adjunct Semaglutide in Adolescents
The study plans to learn more about what happens to the body after bariatric surgery in people 12 to 24 years old. The study aims to understand why people respond differently to bariatric surgery and how to define success beyond…
- Conditions
- Obesity, Adolescent Obesity, Body-Weight Trajectory, Weight Loss Trajectory
- Trial name
- PRESSURE (NCT06575738)
- Testing
- Injectable semaglutide or injectable tirzepatide, Standard postoperative care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Colorado, Denver
Atelectasis, Postoperative, Hypoxia
Physiological Effects and Safety of Continuous High-frequency Oscillatory Ventilation in ICU Patients
Atelectasis, hypoxemia, and ineffective sputum clearance are common problems in ICU patients. Continuous High-Frequency Oscillation (CHFO) is often considered to have a protective effect on the lungs.
- Conditions
- Atelectasis, Postoperative, Hypoxia, Critical Illness
- Trial name
- NCT06702813
- Testing
- High-Frequency Oscillatory Ventilation
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Shanghai Zhongshan Hospital
Chronic Prostatitis (CP), Chronic Pelvic Pain Syndrome (CPPS)
Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is a condition with several causes of which some remain unknown. It is believed that some types of CP may be genetic or passed down (inherited) from one generation to the…
- Conditions
- Chronic Prostatitis (CP), Chronic Pelvic Pain Syndrome (CPPS), Painful Bladder Syndrome (PBS), Benign Frequency Syndrome (BFS)
- Trial name
- CP/CPPS (NCT00499317)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Boston Children's Hospital
BIS, BIS-EEG
Deep Learning Framework for Continuous Depth of Anesthesia Forecasting
The integration of Artificial Intelligence (AI) in anesthesiology offers the potential to shift patient monitoring from reactive to predictive.
- Conditions
- BIS, BIS-EEG, Artifical Intelligence, Intraoperative
- Trial name
- NCT07536230
- Where
- Belgium
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Fever, Triage
Triage Performance and Physiological Predictors of Serious Illness in Febrile Children in the Pediatric Emergency Department
This multicenter prospective observational cohort study evaluates how well the initial triage category assigned by the Turkish Ministry of Health three-level color-coded triage system (Red-Yellow-Green) predicts serious clinical…
- Conditions
- Fever, Triage, Pediatric Emergency Medicine, Serious Bacterial Infection
- Trial name
- PEDTRIAGE (NCT07739004)
- Testing
- Ministry of Health three-level color-coded triage
- Where
- 10 sites in Turkey (Türkiye)
- Volunteers
- 3,000 people
- Sponsor
- TC Erciyes University
Heat Stress, Physiological Stress
Impact of Indoor Overheating on Physiological Strain in Children
Communities worldwide are experiencing increasing heat extremes that challenge the limits of human thermoregulation, particularly among vulnerable populations such as children.
- Conditions
- Heat Stress, Physiological Stress, Cognitive Change
- Trial name
- NCT07261202
- Testing
- Simulated exposure to indoor overheating
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Parkinson's Disease, Obsessive Compulsive Disorder
Physiological Brain Atlas Development
The NIH grant has funded the development of a physiological brain atlas registry that will allow us to significantly improve the data collectioin and use of physiological data into a normalized brain volume.
- Conditions
- Parkinson's Disease, Obsessive Compulsive Disorder, Dystonia, Essential Tremor
- Trial name
- Brain Atlas (NCT00575081)
- Testing
- Stereotactic brain procedures
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Vanderbilt University Medical Center
Visual Impairment, Cerebral Visual Impairment
Promoting Psychophysical Well-being in Children and Adolescents With Visual Impairment
Visual impairment (VI) has significant implications not only for visual functioning, but also for the motor development, psychological well-being, and social participation of children and adolescents.
- Conditions
- Visual Impairment, Cerebral Visual Impairment, Visual Impairments
- Trial name
- VIPPSTAR_UNITN (NCT07703150)
- Testing
- Adapted Physical Activity Programme
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Università degli Studi di Trento
Allergy Testing, Pain, Emotional Symptoms and Physiological Parameters
Pet Therapy Effects on Pain, Emotional and Physiological Responses in Children Undergoing Allergy Testing
In recent decades, the prevalence of allergic diseases, particularly respiratory allergies, has risen significantly. In childhood, house dust mites are the primary indoor allergen in infancy, while the prevalence of pollen…
- Trial name
- NCT06875999
- Testing
- animal assisted therapy
- Volunteers
- 80 people
- Sponsor
- Mehtap METİN KARAASLAN
Neonatal Hyperbilirubinemia
Foot Reflexology and Massage in Neonates Receiving Phototherapy
Neonatal hyperbilirubinemia is a common condition in newborns and is frequently treated with phototherapy. In addition to standard treatment, non-pharmacological interventions such as massage and foot reflexology may help reduce…
- Trial name
- NCT07610811
- Testing
- Foot Reflexology, Body Massage, Phototherapy Device
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Aydin Adnan Menderes University