Clinical trials: Pigmentary Glaucoma
Glaucoma, Open-Angle, Ocular Hypertension
A Study of 0.03% Bimatoprost in the Treatment of Primary Open Angle Glaucoma and Ocular Hypertension
This study will evaluate 0.03% bimatoprost in the treatment of primary open angle glaucoma and ocular hypertension.
- Trial name
- LOTUSDI (NCT02020512)
- Testing
- 0.03% Bimatoprost
- Where
- China
- Volunteers
- 87 people
- Sponsor
- Allergan
Open Angle Glaucoma
Ologen® Collagen Matrix Versus Mitomycin-C in Patients With Juvenile-onset Open Angle Glaucoma
To the best of Investigator knowledge, no studies to this date have compared the safety and efficacyof ologen® Collagen Matrix to MMC in exaggerated healing response among JOAG patients.
- Trial name
- NCT03548805
- Testing
- ologen® Collagen Matrix, Trabeculectomy with low dose mitomycin C
- Where
- India
- Volunteers
- 30 people
- Sponsor
- L.V. Prasad Eye Institute
Childhood Glaucoma
Efficacy and Safety of Topically Applied Medical Therapy for the Treatment of Pediatric Glaucoma
Objectives: The study will assess the ocular hypotensive effect of latanoprost and dorzolamide in a selected sample of patients affected by primary Pediatric Glaucoma (PG), refractory to surgical procedures.
- Trial name
- NCT01527682
- Testing
- Latanoprost, Dorzolamide
- Where
- 2 sites in Italy
- Volunteers
- 37 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Primary Open Angle Glaucoma
Results of Ocular Compression and Suture Release in Trabeculectomy and Combined Surgery
The use of ocular compression and suture release have helped to improve the safety and decrease the risks of glaucoma filtering surgery.
- Trial name
- NCT00327405
- Where
- United States
- Sponsor
- University of Cincinnati
Primary Open Angle Glaucoma, Ocular Hypertension
DSLT for Reducing Medication in Glaucoma
This is a prospective, single arm, open label study conducted at a single site to evaluate the efficacy of Direct Selective Laser Trabeculoplasty (DSLT) in reducing medication burden in patients with medically controlled ocular…
- Trial name
- NCT07390890
- Testing
- Voyager DSLT
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Eye Institute of West Florida
Congenital Glaucoma
Prospective Study of the Diagnostic and Therapeutic Management of Congenital Glaucoma in France
Evidence of a relationship between age at discovery of congenital glaucoma and visual acuity at 4 years of age. The delay in diagnosis is a factor of poor visual acuity.
- Trial name
- Conglau (NCT03077789)
- Testing
- TRABECULOTOMY
- Where
- 24 sites in France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Lille
Congenital Glaucoma
Genetic Testing in Primary Congenital Glaucoma Patients
Primary congenital glaucoma patients and their immediate relatives will undergo complete ophthalmic examination and an interview with a geneticist. A blood sample will be drown from all participants for DNA analysis.
- Trial name
- NCT01136460
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Open-Angle Glaucoma, Ocular Hypertension
A Phase III Study of Brimonidine Tartrate Ophthalmic Solution, 0.15% in Patients With Open-Angle Glaucoma or Ocular Hypertension
The primary objective of this study is to compare the safety and efficacy of Brimonidine Tartrate Ophthalmic Solution, 0.15% in patients with open-angle glaucoma or ocular hypertension.
- Trial name
- NCT00061529
- Testing
- Brimonidine Tartrate Ophthalmic Solution
- Where
- United States
- Sponsor
- Alcon Research
Glaucoma, Open-Angle, Ocular Hypertension
GANfort® in Patients With Primary Open Angle Glaucoma or Ocular Hypertension Who Are Insufficiently Responsive to Monotherapy
This is an observational study of patients diagnosed with Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) who are insufficiently responsive to monotherapy and who are prescribed GANfort® (fixed combination of 0.3…
- Trial name
- NCT01628601
- Testing
- Fixed combination 0.3 mg bimatoprost and 5 mg timolol
- Where
- Austria
- Volunteers
- 392 people
- Sponsor
- Allergan
Ocular Hypertension, Open-angle Glaucoma
Double-masked Study of AR-13324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension
To evaluate the ocular hypotensive efficacy and ocular and systemic safety of AR-13324 Ophthalmic Solution, 0.02% compared to the active comparator Timolol maleate Ophthalmic Solution, 0.5%
- Trial name
- Rocket-1 (NCT02207491)
- Testing
- Timolol maleate Ophthalmic Solution 0.5% BID, AR-13324 Ophthalmic Solution 0.02%
- Where
- United States
- Volunteers
- 411 people
- Sponsor
- Aerie Pharmaceuticals
Open Angle Glaucoma (OAG)
CyPass Clinical Experience Study
This study is to evaluate the long-term safety, effectiveness and clinical experience of the CyPass Micro-Stent in patients with glaucoma.
- Trial name
- CyCLE (NCT01097174)
- Testing
- CyPass Micro-Stent
- Where
- 14 sites in Austria, Bulgaria and 4 more
- Volunteers
- 555 people
- Sponsor
- Transcend Medical, Inc.
Primary Congenital Glaucoma
Iris Tissue in Primary Congenital Glaucoma
To present the histopathological features of the iris tissue in primary congenital glaucoma which may play a role in pathogenesis
- Trial name
- NCT04079725
- Testing
- Combined trabeculotomy-trabeculectomy with mitomycin c
- Volunteers
- 15 people
- Sponsor
- Assiut University
Glaucoma, Open-Angle, Circadian Rhythm
Circadian Variations in Ocular Blood Flow in Glaucomatous and Normal Eyes
After focusing many years only on intraocular pressure (IOP) as the primary risk factor, recently the impact of ocular blood flow is getting more consideration for the pathophysiology of glaucoma.
- Conditions
- Glaucoma, Open-Angle, Circadian Rhythm, Intraocular Pressure, Regional Blood Flow
- Trial name
- NCT00707226
- Where
- Austria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Open Angle Glaucoma (OAG)
Conventional Non-Penetrating Deep Sclerectomy Versus Modified Subflap Mattress Suture in OAG
The goal of this clinical trial is to learn if modified non-penetrating deep sclerectomy (NPDS) with a sub-flap mattress suture works to treat open-angle glaucoma (OAG).
- Trial name
- NCT07425743
- Testing
- Modified Deep Sclerectomy with Ahmed's sub-flap mattress suture (modified NPDS), Conventional Nonpenetrating Deep Sclerectomy (NPDS)
- Where
- 2 sites in Egypt
- Volunteers
- 26 people
- Sponsor
- Beni-Suef University
Primary Open Angle Glaucoma
Transconjunctival Needling Revision Versus Medical Treatment
When the glaucoma filtering surgery failures (intraocular pressure rises again), the options is start to use the hypotensive eye drops again (medical treatment).
- Trial name
- NCT01887223
- Testing
- Transconjunctival needling revision, Medical treatment
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo General Hospital
Glaucoma, Open-Angle, Ocular Hypertension
A Study of Patients With Primary Open Angle Glaucoma or Ocular Hypertension Who Were Insufficiently Responsive to Monotherapy
This is a retrospective chart review and will assess changes in IOP after treatment with any fixed combination in patients who previously received monotherapy.
- Trial name
- NCT01637246
- Testing
- Any Fixed Combination Therapy
- Where
- Spain
- Volunteers
- 4,385 people
- Sponsor
- Allergan
Primary Congenital Glaucoma
MicrocatheterTrabeculotomy in Primary Congenital Glaucoma
PURPOSE: To study circumferential trabeculotomy for congenital glaucoma using Glaucolight illuminated microcatheter. Setting: Ophthalmology department, Faculty of Medicine, Minia University, 61519, El-Minia, Egypt.
- Trial name
- NCT04116450
- Testing
- Glaucolight illuminated microcatheter.
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Minia University
Primary Open Angle Glaucoma (POAG)
UBM Evaluation After Combined Deep Sclerectomy With Trabeculotomy in Primary Open Angle Glaucoma
Primary open-angle glaucoma is a chronic optic neuropathy that often requires surgical intervention when medical treatment fails.
- Trial name
- NCT07454447
- Testing
- Ultrasound Biomicroscopy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University Hospital
Glaucoma, Primary Open Angle, Ocular Hypertension
A Study of Patients With Primary Open Angle Glaucoma or Ocular Hypertension Switched to Lumigan® UD Monotherapy for Medical Reasons
The study will evaluate patients diagnosed with primary open angle glaucoma or ocular hypertension who are switched to Lumigan® UD monotherapy for medical reasons in accordance with physician standard clinical practice.
- Trial name
- NCT01853085
- Testing
- Bimatoprost Ophthalmic Solution
- Where
- Germany
- Volunteers
- 1,830 people
- Sponsor
- Allergan
Open Angle Glaucoma (OAG)
iStent Inject Versus Goniotomy With Kahook Dual Blade in Glauocma Treatment
The purpose of the study is to investigate the efficacy of cataract surgery in combination with Kahook Dual Blade Glide goniotomy (KDB) or iStent Inject W Trabecular Microbypass Stent (Istent) in eyes with Open-angle glaucoma.
- Trial name
- iSKDB (NCT07325552)
- Testing
- Goniotomy with KDB blade goniotomy, Two iStent inject implanation
- Where
- 2 sites in Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Bialystok