Clinical trials: Pigmentation
Vitiligo, Hearing Loss
Audiological Disturbances in Vitiligo
The purpose of this study is to determine wether vitiligo patients have more audiological abmnormalities, than the healthy population.
- Trial name
- NCT00484224
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Retinal Dystrophies, Age-related Macular Degeneration
Retinal Imaging by Adaptive Optics in Healthy Eyes and During Retinal and General Diseases
Using an adaptive optics imaging device, retinal structures are observed in healthy and diseased subjects.
- Conditions
- Retinal Dystrophies, Age-related Macular Degeneration, Arterial Hypertension, Diabetes
- Trial name
- iPhot (NCT01546181)
- Where
- France
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Metabolic Syndrome, Vitiligo
Metabolic Syndrome in Early Onset Versus Late Onset Vitiligo
This study aims at detection of possible associated metabolic syndrome with vitiligo and assessment of possible contribution of the age of onset of vitiligo.
- Trial name
- NCT03622320
- Testing
- Blood sample
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hyper-IgM Syndrome, Ectodermal Dysplasia
Studies of Disorders in Antibody Production and Related Primary Immunodeficiency States
This study investigates gene abnormalities in Primary Immune Deficiency(PID) with a goal of improving the diagnosis and treatment of patients. The specific disorders include: 1.
- Trial name
- NCT00266513
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Obesity, Acanthosis Nigricans
Children's Healthy Living Community Randomized Trial
The goal is to build social/cultural, political/economic, and physical/built environments that will promote active play and intake of healthy food to prevent young child obesity in the Pacific Region.
- Conditions
- Obesity, Acanthosis Nigricans, Central Obesity
- Trial name
- CHL (NCT01881373)
- Testing
- CHL program, Delayed Optimized CHL program
- Where
- United States
- Volunteers
- 9,840 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
RAS Mutation, Neurofibromatosis 1
RASopathy Biorepository
The RASopathies are a group of developmental disorders caused by genetic changes in the genes that compose the Ras/mitogen activated protein kinase (MAPK) pathway. New RASopathies are being diagnosed frequently.
- Conditions
- RAS Mutation, Neurofibromatosis 1, Noonan Syndrome, Noonan Syndrome With Multiple Lentigines
- Trial name
- NCT04395495
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Healthy Participants
the Effect of Different Background Color and Skin Tone on the Accuracy of Auricular Scanning
The goal of this study is to find the best miss and match background color around an ear when taking scans for it , the investigators will recruit participants of three different skin tone and will scan their ear three times; one…
- Trial name
- NCT07108946
- Testing
- Black background, White background, Participant own skin as a background
- Where
- Egypt
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- yasmine Elsherbeeny
Macular Pigmentation, Skin Pigment
Macular Pigment Measurements in Eye & Other Tissues
The purpose of this study is to understand the role of nutrition and its effects on the eye and other tissues. The investigators propose to study this by validating and correlating various non-invasive measurement methods of…
- Trial name
- NCT03022773
- Testing
- Carotenoid measurements
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Utah
Diabetic Retinopathy, DR
Epivascular Glia Regression and Macular Pigment Restoration After Faricimab in Diabetic Retinopathy
The aim of the study is to evaluate in diabetic patients affected by diabetic retinopathy epivascular glia regression and macular pigment restoration after faricimab injection in diabetic retinopathy in a 1 year follow up
- Trial name
- GLIA-MAC (NCT07526857)
- Testing
- Faricimab Injection [Vabysmo], Aflibercept (2.0 mg)
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federico II University
Hyperpigmentation, Post-inflammatory Hyperpigmentation
The Effects of Cetyl Tranexamate Mesylate on the Appearance of Acne-Related Hyperpigmentation
The purpose of this study is to assess the effects of Cetyl Tranexamate Mesylate on acne-related hyperpigmentation through a specific delivery form known as TeraCeutic TXVector.
- Conditions
- Hyperpigmentation, Post-inflammatory Hyperpigmentation, Acne
- Trial name
- NCT06080035
- Testing
- Topical Cetyl Tranexamate Mesylate
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Melanoma, Dysplastic Nevi
Family Study of Melanoma in Italy
During the course of a case-control study of melanoma conducted at the Bufalini Hospital, Cesena, Italy in the years 1994-1996, 20 families with 2 or 3 melanoma cases were identified and studied.
- Conditions
- Melanoma, Dysplastic Nevi, Melanocytic Nevi
- Trial name
- NCT00339222
- Where
- 7 sites in Italy, Spain
- Volunteers
- 1,708 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Vitiligo, Generalized
Evaluation Safety ,Efficacy Baricitinib Plus Excimer Light Versus Excimer Light Alone in Non Segmental Vitiligo
The study aims to evaluate the safety and efficacy of the combination of topical baricitinib and 308-nm monochromatic excimer light versus 308-nm monochromatic excimer light alone in treatment of non-segmental vitiligo.
- Trial name
- NCT05950542
- Testing
- Baricitinib
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Psoriasis
Levels of Pigment Epithelium-derived Factor in Patients With Psoriasis.
Psoriasis is an immune-mediated chronic inflammatory skin disease associated with increase interaction of inflammatory mediators like adipokines.
- Trial name
- NCT05252741
- Testing
- serum samples and punch skin biopsies
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Sohag University
Neonatal Hyperbilirubinemia
Study on Newborn Babies With a Yellow Skin Color (Neonatal Jaundice Study)
Background: Neonatal hyperbilirubinemia is the most common reason for admission in the neonatal period (first month of life) worldwide and at SMRU.
- Trial name
- NCT02361788
- Where
- Thailand
- Volunteers
- 1,710 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Vitiligo Vulgaris
Questionnaire and Laboratory Data on Vitiligo Vulgaris
Vitiligo vulgaris is an autoimmune disorder that causes loss of pigmentation over the skin, hair and mucous membranes (e.g. lips, nose, genitals).
- Trial name
- NCT01206374
- Where
- 2 sites in United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Vitiligo
5-fluorouracil for Treatment of Stable Vitiligo
Vitiligo, a significant dermatologic challenge affecting 0.5 to 2% of the global population. Despite various existing medical approaches, current vitiligo treatments are still far from optimal.
- Trial name
- NCT06209138
- Testing
- 5 fluorouracil, Saline
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Peutz-Jeghers Syndrome
Study of Accurate Diagnosis and Treatment of Peutz-Jeghers Syndrome
The mutation of STK11 has been regcognized to be the major cause of Peutz-Jeghers syndrome (PJS).The aim of this study was to confirm the mutation rate of gene associated with gastrointestinal malignancies,including STK11…
- Trial name
- NCT03806075
- Testing
- Second generation sequencing, 16s rRNA gene sequencing
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Yiqi Du
Vitiligo, Generalized
Gasdermin D Expression in Generalized Vitiligo Patients After Narrow-band Ultraviolet B Therapy
The aim of this study is to: 1. Evaluate the role of tissue Gasdermin D expression using immunehistochemstry techniques in patients with generalized vitiligo and compare it with healthy controls. 2.
- Trial name
- NCT06546059
- Testing
- narrow band ultraviolet-B
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- South Valley University
Healthy
Normal Human Electro-Oculogram
This study will measure the normal range of the human electro-oculogram (EOG) in people of various age groups. EOGs are recordings of electrical signals generated by the retina (the light-sensitive tissue in the back of the eye)…
- Trial name
- NCT00001610
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Sunburn, Sun Damaged Skin
Natural Sunlight Protection and Simulated Sunlight Protection Offered by Sunscreens and Fabrics
The purpose of this study is to assess how human skin reacts and how sunscreens and sun protection fabrics protect in natural sunlight compared to their labeled claims, indoor testing methods (existing or modified) and…
- Conditions
- Sunburn, Sun Damaged Skin, Overexposure to Sun Rays
- Trial name
- NCT03007589
- Testing
- otc sunscreens, sun protection fabrics, Optical Filters
- Where
- 5 sites in United States, Chile and 1 more
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sun Protection Foundation