Clinical trials: Plaque
Gingival Diseases
Centella Asiatica (Gotukola) Mouthwash as an Adjunct to Mechanical Plaque Control
This study evaluates the adjunctive use of Centella Asiatica (gotukola) to scaling in the reduction of plaque and gingival inflammation.
- Trial name
- NCT02827305
- Testing
- Gotukola, Scaling
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Sri Hasanamba Dental College and Hospital
Psoriasis
A Study to Evaluate the Safety of Raptiva in Adults With Plaque Psoriasis Previously Enrolled in Study ACD2600g
This is an open label, multicenter study designed to evaluate the safety and tolerability of efalizumab administered subcutaneously at weekly doses of 1.0 mg/kg in subjects with plaque psoriasis who previously participated in…
- Trial name
- NCT00096603
- Testing
- Raptiva (efalizumab)
- Volunteers
- 450 people
- Sponsor
- Genentech, Inc.
Plaque Psoriasis
Adrenal Suppression and Pharmacokinetics of Topicort® Spray, 0.25% in Pediatric Patients With Plaque Psoriasis
The objective of this study is to evaluate the potential of Topicort® (desoximetasone) Topical Spray, 0.25% to suppress hypothalmic pituitary adrenal axis function.
- Trial name
- NCT02340169
- Testing
- Topicort® (desoximetasone) Topical Spray, 0.25%
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Dental Caries
Oral Alkali Production and Caries Prevention in Children (Longitudinal)
The fact that dental caries remains a major public health problem mandates that oral-health researchers explore new strategies for assessment of caries risk, as well as for caries prevention and management.
- Trial name
- NCT02398695
- Testing
- Oral Samples
- Where
- United States
- Volunteers
- 232 people
- Sponsor
- University of Florida
Generalized Aggressive Periodontitis
Triclosan as Adjunctive Therapy in the Plaque Control in Children From Generalized Aggressive Periodontitis Families.
Generalized aggressive periodontitis (GAP) is an inflammatory disease that causes the severe and rapid destruction of periodontal tissue.
- Trial name
- NCT03642353
- Testing
- Triclosan
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Plaque Induced Gingival Disease, Oral Health
Effect of Benzydamine Hydrochloride Mouthrinse on Plaque Accumulation in Periodontally Healthy Female Subjects
The goal of this clinical trial is to evaluate the effect of a mouthrinse containing an active ingredient benzydamine hydrochloride in the absence of daily oral hygiene.
- Trial name
- BHCl-PLAQUE (NCT07565766)
- Testing
- Benzydamine hydrochloride mouthrinse
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Acute Coronary Syndrome, Myocardial Infarction
Exploring the MEchanism of Plaque Rupture in Acute Coronary Syndrome Using Coronary CT Angiography and computationaL Fluid Dynamic
The EMERALD trial is a multinational, multicenter study. The patients presented with AMI/definite evidence of plaque rupture and had underwent coronary CT angiography from 1 month to 2 year prior to the event will be…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Plaque, Atherosclerotic, Rupture, Spontaneous
- Trial name
- EMERALD (NCT02374775)
- Where
- 2 sites in South Korea
- Volunteers
- 77 people
- Sponsor
- Seoul National University Hospital
Peri-Implant Health
Plaque and Bleeding on Probing Around Implants Supporting Fixed Full-Arch Dental Prostheses
This observational study examines plaque, hard deposits (calculus), and gum bleeding around dental implants supporting fixed full-arch dental prostheses.
- Trial name
- NCT07898956
- Testing
- Prosthetic Maintenance History
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nicola Alberto Valente, DDS, MS, PhD
Plaque Removal
Comparison of New and 3-Month-Old Toothbrush in the Removal of Plaque in Children
This study aimed to validate or invalidate non-inferiority in the plaque removal efficacy of old versus new toothbrushes in the hands of 7-9 year old children.
- Trial name
- NCT00836784
- Testing
- old toothbrush, New tooth brush
- Where
- Iran
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University
Plaque Induced Gingivitis
Compare the Effect of Green Tea Mouthwash vs Chlorohexidine Mouthwash in Children With Plaque-induced Gingivitis
This study aims to assess and compare the effect of green tea mouthwash compared to chlorohexidine mouthwash in reducing gingivitis and plaque scores (in terms of plaque index and gingival index) in children with plaque-induced…
- Trial name
- NCT05803590
- Testing
- Green tea mouthwash, Chlorhexidine mouthwash
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Plaque Psoriasis
Adrenal Suppression and Absorption Study of Halobetasol Propionate Foam in Subjects 12-17 With Plaque Psoriasis
The purpose of this study is to evaluate Halobetasol Propionate (HBP) foam, 0.05% in subjects aged 12 through less than 18 years with plaque psoriasis in order to check the safety, the potential to suppress the adrenal glands and…
- Trial name
- NCT03992261
- Testing
- Halobetasol Topical Foam
- Where
- 11 sites in United States, Georgia and 2 more
- Volunteers
- 24 people
- Sponsor
- Mayne Pharma International Pty Ltd
Moderate to Severe Chronic Plaque-type Psoriasis
Study to Assess the Long-term Safety, Tolerability, Efficacy of Secukinumab in Pediatric Patients of Age 6 to <18 Years, With Moderate to Severe Plaque Psoriasis
This was an open-label, parallel-group, two-arm, multicenter study in pediatric subjects aged 6 years to less than 18 years, at randomization, with moderate to severe chronic plaque psoriasis.
- Trial name
- NCT03668613
- Testing
- secukinumab low dose, secukinumab high dose
- Where
- 23 sites in United States, Belgium and 7 more
- Volunteers
- 84 people
- Sponsor
- Novartis Pharmaceuticals
Plaque Psoriasis, Psoriatic Arthritis
A Clinical Study of Increased Dose of TA-650 in Patients With Psoriasis
The purpose of this study is to evaluate the efficacy, safety and pharmacokinetics of TA-650 at increased dose of 10 mg/kg every 8 weeks in patients with psoriasis in whom effect of the treatment was confirmed after the treatment…
- Conditions
- Plaque Psoriasis, Psoriatic Arthritis, Pustular Psoriasis (Excluding a Localized), Psoriatic Erythroderma
- Trial name
- NCT01680159
- Testing
- TA-650
- Where
- 7 sites in Japan
- Volunteers
- 51 people
- Sponsor
- Tanabe Pharma Corporation
Plaque-Induced Gingivitis, Dental Plaque Accumulation
Innovative Mouthwash in School-Aged Children With Fixed Orthodontic Appliances
Fixed metal orthodontic appliances create additional plaque-retentive areas around brackets, archwires and ligatures, making mechanical plaque control more difficult in children and adolescents.
- Conditions
- Plaque-Induced Gingivitis, Dental Plaque Accumulation, Halitosis
- Trial name
- NCT07710144
- Testing
- Test mouthwash, Chlorhexidine-containing mouthwash
- Where
- Bulgaria
- Volunteers
- 90 people
- Sponsor
- Plovdiv Medical University
Dental Plaque, Gingivitis
Mechanical Plaque Control and Gingivitis Reduction in Fixed Appliance Patients
The purpose of this study is to determine whether the use of a sonic toothbrush alone is more effective than two other toothbrushing protocols on dental plaque elimination in patients with fixed orthodontic appliances.
- Trial name
- NCT00681135
- Testing
- sonic toothbrush (Philips Sonicare® FlexCare, Typ HX6942/04), manual toothbrush / interdental toothbrush (elmex® Inter X medium toothbrush / interdental brush Curaprox®), manual toothbrush (elmex® Inter X medium toothbrush)
- Where
- Germany
- Volunteers
- 118 people
- Sponsor
- Sebastian Zingler
Plaque
Metagenomic and Metatranscriptomic Analysis of Clinical Plaque Samples
The objective of this study is to determine the metagenomic and metatranscriptomic analysis of clinical samples.
- Trial name
- NCT05138978
- Testing
- Colgate Maximum Cavity Protection plus Sugar Acid Neutralizer, Colgate Cavity Protection
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Oral Health Behavior Change
SEHAT Virtual Oral Health Promotion for School Adolescents in Pakistan
The goal of this cluster-randomized trial is to learn if the SEHAT program works to improve oral health among school adolescents in Pakistan. It will also assess how the program affects oral health behaviors and knowledge.
- Trial name
- SEHAT (NCT07536958)
- Testing
- SEHAT Virtual Oral Health Education, Conventional Oral Health Education
- Where
- Pakistan
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Shifa College of Dentistry
Black Stain, Black Plaque
Air Polishers With Erythritol in the Treatment of Dental Black Stain of Bacterial Origin
Black stains on the teeth, caused by the accumulation of chromogenic microorganisms that produce iron compounds, are more common in the pediatric population and have a negative impact on dental aesthetics and patients'…
- Trial name
- NCT06720168
- Testing
- Erythritol air polisher, Dental prophylaxis with ultrasonic treatment
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Cardenal Herrera University
Dental Plaque, Dental Prophylaxis
Effectiveness of Customized Handle Toothbrush
People with special needs suffer from many difficulties, including mental, physical or motor, which increase the difficulty of obtaining good oral health.
- Conditions
- Dental Plaque, Dental Prophylaxis, Dental Care
- Trial name
- NCT04845633
- Testing
- Evaluation of the Effectiveness of Conventional Toothbrush in Dental Plaque Control in Healthy Children, Evaluation of the Effectiveness of Customized Handle Toothbrush in Dental Plaque Control in Healthy Children, Evaluation of the Effectiveness of Conventional Toothbrush in Dental Plaque Control in Children with Down Syndrome
- Where
- Syria
- Volunteers
- 48 people
- Sponsor
- Damascus University
Orthodontic Appliance Complication
The Effect of Different Remineralizing Agents on White Spot Lesions and Dental Plaque During Orthodontic Retention
Dental caries is a decay process that breaks down the tooth. The earliest clinical signs of active dental caries is seen as 'white spot lesions' (WSLs).
- Trial name
- NCT04788550
- Testing
- Fluoridated toothpaste, fluoride varnish (5% sodium fluoride), CPP-ACP plus crème group
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Malaya