Clinical trials: Pleural Cavity Effusion
Other Acute Illnesses Presenting to the Hospital, Heart Failure
Evaluation of Implementation of a National Point-of-Care Ultrasound Training Program
This VA QUERI Partnered Evaluation Initiative will evaluate the impact of an immersive Point-of-care Ultrasound (POCUS) Training Course on provider skill acquisition and retention; the frequency of POCUS use by trained providers…
- Conditions
- Other Acute Illnesses Presenting to the Hospital, Heart Failure, Pneumonia, Deep Venous Thrombosis
- Trial name
- NCT03296280
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Bronchiolitis Acute
Use of Lung Ultrasound in Children With Acute Bronchiolitis
Bronchiolitis is the leading cause of hospitalization in infants. The diagnosis is clinical and chest x-ray (CXR) should be reserved for severe cases in which signs of pulmonary complications are present.
- Trial name
- NCT03280732
- Testing
- Lung Ultrasound
- Where
- Italy
- Volunteers
- 87 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Pneumonia, Pleural Effusion
Physiotherapy Technique Decreases Respiratory Complications After Cardiac Operation
The objective of this study is to assess whether there is a difference between a care protocol with the use of incentive spirometry (Voldyne ®) and another with the application of NIV (non invasive ventilation with single-level…
- Conditions
- Pneumonia, Pleural Effusion, Atelectasis
- Trial name
- NCT01416519
- Testing
- Continuous Positive Airway Pressure (CPAP) facial mask, Assisted deep inspiration technique
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Santa Casa de Votuporanga
Malignant Pleural Effusion, Thoracic Cancer
Video Assisted Thoracoscopic Surgery (VATS) - Surgical Pleurodesis vs Tube Drainage in Management of Malignant Pleural Effusion (MPE)
Malignant Pleural Effusion (MPE) is considered to be a common presentation at malignant tumors representing 15% of all cancer cases. It carries a burden on our patients with dyspnea being the most common symptom in most of cases.
- Trial name
- NCT05872126
- Testing
- VATS-Surgical pleurodesis, Tube Drainage
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Parapneumonic Pleural Effusion, Empyema
Clinical Trial Corticoids For Empyema And Pleural Effusion In Children
STUDY JUSTIFICATION 1. Scientific evidence of the usefulness of corticosteroid use for infectious diseases: Corticosteroids along with antibiotic use improve survival in some infectious processes provide long term benefits and…
- Trial name
- CORTEEC (NCT01261546)
- Testing
- Dexamethasone
- Where
- 8 sites in Spain
- Volunteers
- 60 people
- Sponsor
- Hospital Infanta Sofia
Peritoneum Cancer, Peritoneum Neoplasm
International Registry of Patients Treated With Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC)
Multicentric, international, web-based prospective documentation of the indications and results of Pressurized Aerosol Chemotherapy (so-called PIPAC or PITAC) for treating malignant pleural and peritoneal diseases.
- Conditions
- Peritoneum Cancer, Peritoneum Neoplasm, Pleural Cancer, Pleural Effusion
- Trial name
- PIPACRegis (NCT03210298)
- Testing
- PIPAC
- Where
- 16 sites in Argentina, Australia and 11 more
- Volunteers
- 1,000 people
- Sponsor
- Sabine Rhode
Pleural Effusion
Effect of Bubble Positive Expiratory Pressure and Segmental Breathing Versus Incentive Spirometry in Pleural Effusion
Conducted as a randomized clinical trial, this study will include 40 pediatric participants aged 5-16, recruited from Gulab Devi Chest Hospital and Children's Hospital, Lahore.
- Trial name
- NCT07248774
- Testing
- Bubble PEP, Incentive Spirometery
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Pleural Effusion, Coronary Artery Bypass
Pleural Effusion Following Cardiac Surgery: Prevalence, Risk Factors and Clinical Features
Pleural effusion is a common complication of cardiac surgery. The aim of this study was to determine the prevalence, characteristics and determinants of clinically significant pleural effusions, defined as those requiring…
- Trial name
- NCT00665015
- Where
- Canada
- Volunteers
- 2,892 people
- Sponsor
- Laval University
Pleural Effusion, Malignant
The Value of PET-CT in Pleural Effusions
The investigators aim is to asses the diagnostic power of 18F-FDG PET-CT in discriminating malignant from nonmalignant causes in patients with a recurrent unilateral pleural effusion of unknown origin.
- Trial name
- NCT03272997
- Where
- Denmark
- Volunteers
- 112 people
- Sponsor
- Naestved Hospital
Critically Ill, Acute Lung Injury
Respiratory Mechanics and Pleural Effusion
The investigators aim to compare the respiratory mechanics in acute lung injury (ALI)/acute respiratory diseases syndrome (ARDS) patients with and without pleural effusion.
- Conditions
- Critically Ill, Acute Lung Injury, ARDS
- Trial name
- NCT00258518
- Testing
- mechanical ventilation/CT Scan
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Policlinico Hospital
Chylous Pleural Effusion Following Cardiothoracic Surgery
Fortified Skimmed Mother's Milk in the Management of Chylothorax
The purpose of this study is to determine if the use of fortified skimmed mother's milk is a safe alternative to specialized formula in the treatment of chylothorax following cardiothoracic surgery.
- Trial name
- NCT01673165
- Testing
- Skimmed mother's milk, Specialized Formula
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Oregon Health and Science University
Pleural Effusion
Comparison of Thoracoscopic Talc Pleurodesis by Thoracic Epidural or General Anesthesia
Video-assisted thoracoscopic surgery (VATS) talc pleurodesis is often carried out in patients with malignant recurrent pleural effusion to relieve symptoms and prevent recurrence.
- Trial name
- NCT01469728
- Testing
- Non-awake VATS talc pleurodesis, Awake VATS talc pleurodesis
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Rome Tor Vergata
Tuberculosis, Pleural Effusion
Efficacy Study of Thrice Weekly Directly Observed Treatment Short-Course Regimen in Tubercular Pleural Effusion
Tubercular pleural effusion is the second most common form of extrapulmonary tuberculosis (EPTB) seen in clinical practice after tuberculosis (TB) lymphadenitis.
- Trial name
- NCT01560078
- Where
- India
- Volunteers
- 360 people
- Sponsor
- All India Institute of Medical Sciences
Empyema, Pleural
Comparison of Intrapleural Urokinase and Video-Assisted Thorascopic Surgery in the Treatment of Parapneumonic Pleural Effusion in Children
Despite the improvement in the technology available for diagnosing and treating empyema, the management of empyema in children remains controversial.
- Trial name
- UROVATS (NCT02165891)
- Testing
- insertion of a chest drain with urokinase instillation, primary video-assisted thorascopic surgery
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Queen Fabiola Children's University Hospital
Lung Neoplasm, Lung Diseases, Interstitial
Respiratory Endoscopy: Diagnostic Yield, Technical Factors and Complications
Background: Respiratory endoscopy comprises flexible bronchoscopy and medical thoracoscopy. The diagnostic yield, technical factors and complications for all patient sub-populations is still not clearly defined.
- Conditions
- Lung Neoplasm, Lung Diseases, Interstitial, Respiratory Tract Infections, Pleural Effusions
- Trial name
- NCT01374542
- Testing
- Respiratory endoscopy
- Where
- Singapore
- Volunteers
- 4,000 people
- Sponsor
- Singapore General Hospital
Complicated Pleural Effusion/ Empyema
Efficacy of Fibrinolytic Agents in Complicated Pleural Effusion
Intrapleural administration of fibrinolytic therapy, urokinase in parapneumonic effusion and empyema has been shown to decrease the need for surgical intervention and length of hospital stay.
- Trial name
- NCT03716375
- Testing
- Intrapleural Medications
- Volunteers
- 80 people
- Sponsor
- Beijing Children's Hospital
Pleural Effusion Due to Another Disorder (Disorder)
Natural History of Nonspecific Pleuritis Diagnosed After Video-assisted-thoracoscopic-surgery
The investigators want to determine the incidence of malignant disease, type of malignant disease and overall survival in patients diagnosed with NSP after VATS.
- Trial name
- NCT03270228
- Testing
- Nonspecific pleuritis after VATS thoracoscopy
- Where
- Denmark
- Volunteers
- 10,000 people
- Sponsor
- Naestved Hospital
Pleural Effusion
Normal Saline Flushing With And Without Heparin Lock In Maintaining Small Bore Intercostal Chest Catheter (ICC) Patency
Pleural diseases are among the most common clinical problems encountered in healthcare settings in Malaysia and even worldwide. Most patients presented in a hospital setting with pleural diseases will need pleural aspirations or…
- Trial name
- SENSHIP (NCT06314620)
- Testing
- Heparin saline lock, Without heparin saline lock
- Where
- Malaysia
- Volunteers
- 40 people
- Sponsor
- National University of Malaysia
Pleural Effusion, Pleurisy
Yield of Cryoprobe vs Flexible Forceps Pleural Biopsy
This is a prospective study to assess the yield of pleural biopsy obtained with the routine flexible thoracoscopic biopsy forceps versus that obtained with a flexible cryoprobe during semirigid thoracoscopy
- Conditions
- Pleural Effusion, Pleurisy, Tuberculosis, Metastatic Malignancy
- Trial name
- COFFEE (NCT02500277)
- Testing
- Cryoprobe pleural biopsy first, Flexible forceps biopsy first
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Pulmonary Nodules, Solitary, Pulmonary Nodules, Multiple
AI Assisted Detection of Chest X-Rays
This study has been added as a sub study to the Simulation Training for Emergency Department Imaging 2 study (ClinicalTrials.gov ID NCT05427838).
- Conditions
- Pulmonary Nodules, Solitary, Pulmonary Nodules, Multiple, Pulmonary Consolidation, Pneumothorax
- Trial name
- AID-CXR (NCT06075836)
- Testing
- Cases reading, Ground truthing
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust