Clinical trials: Poisoning
Complex Congenital Heart Defect, Dysfunctional RVOT Conduit
COMPASSION S3 Post-Approval Study
This study will monitor device performance and outcomes of the SAPIEN 3 Transcatheter Heart Valve (THV) System in subjects with a dysfunctional right ventricular outflow tract (RVOT) conduit or previously implanted surgical valve…
- Conditions
- Complex Congenital Heart Defect, Dysfunctional RVOT Conduit, Pulmonary Valve Insufficiency, Pulmonary Valve Degeneration
- Trial name
- NCT04860765
- Testing
- SAPIEN 3 THV
- Where
- 19 sites in United States
- Volunteers
- 150 people
- Sponsor
- Edwards Lifesciences
Poisoning by Scorpion Sting
A Trial of Equine F (ab')2 Antivenom for Treatment of Scorpion Envenomation in Morocco
This study has the objective to demonstrate the effectiveness of Alacramyn NAMO in the treatment of North Africa and Middle East scorpions envenomation by reducing the severity of envenomation.
- Trial name
- NCT01336660
- Testing
- Equine F(ab')2 antivenom
- Where
- 2 sites in Morocco
- Volunteers
- 56 people
- Sponsor
- Instituto Bioclon S.A. de C.V.
Scorpion Sting
Open Label Clinical Trial of Anascorp® in Pediatric Patients With Scorpion Sting Envenomation
There is no FDA approved therapy for the treatment of scorpion envenomation. Centruroides scorpion envenomation produces a pattern of neurotoxicity with a spectrum of severity ranging from trivial to life threatening.
- Trial name
- NCT01599936
- Testing
- Anascorp
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Instituto Bioclon S.A. de C.V.
Obstruction; Airway, With Asthma
Impedance Pneumography Measurement During Acute Airway Obstruction and Recovery Phase in Young Children
The purpose of this study is to evaluate the association of signals recorded and analysed with Ventica® LFTS in infants and preschoolers during acute airway obstruction/asthma exacerbation and recovery thereof for changes in the…
- Trial name
- NCT03488303
- Where
- Croatia
- Volunteers
- 30 people
- Sponsor
- Revenio Research
Mechanical Ventilation, Pneumonia
Removal of Endotracheal Tube Secretions Comprehensively Until Extubation
The purpose of this study is to measure secretion accumulation within endotracheal tubes of mechanically ventilated patients and test the efficacy, safety and clinical impact of removing the secretions using novel airway…
- Trial name
- RESCUE (NCT00663637)
- Testing
- CAM (Complete Airway Management) Catheters
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- O. M. Neotech, Inc.
Scorpion Sting Envenomation
Establishment of Natural History of Scorpion Envenomation
This retrospective study was conducted to collect data from approximately 100 patients from 6 months to 18 years of age who were stung by a scorpion but were not treated with antivenom.
- Trial name
- NCT00696683
- Testing
- None, this is an observational study
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Instituto Bioclon S.A. de C.V.
Parkinson Disease, Dyskinesia, Drug-Induced
Open Label, Safety, Tolerability and Efficacy of AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesias
The purpose of this study is to generate long-term safety, tolerability and efficacy data for AFQ056 in patients who have participated in and completed any AFQ056 phase II study in PD-LID (Parkinson's disease, L-dopa induced…
- Conditions
- Parkinson Disease, Dyskinesia, Drug-Induced, Levodopa
- Trial name
- NCT01173731
- Testing
- AFQ056
- Where
- 22 sites in United States, Australia and 4 more
- Volunteers
- 66 people
- Sponsor
- Novartis Pharmaceuticals
Snake Bite
Study to Evaluate the Efficacy of Two Treatment Schemes With Antivipmyn ® for the Treatment of Snake Bite Envenomation
The purpose of this study is to compare whether a same total dose given up front as a single dose is more effective and as safe as the same dose given as a fractioned dose.
- Trial name
- NCT00639951
- Testing
- A, Antivipmyn ®
- Where
- 5 sites in Mexico
- Volunteers
- 10 people
- Sponsor
- Instituto Bioclon S.A. de C.V.
Botulism
BT-011 Pharmacokinetics of Botulism Antitoxin Heptavalent in Pediatric Patients
The purpose of this study is to verify the pediatric dosing recommendations for BAT product in pediatric patients that are treated with BAT product due to a confirmed or suspected case of botulism.
- Trial name
- NCT02051062
- Testing
- Blood sample collection
- Volunteers
- 10 people
- Sponsor
- Emergent BioSolutions
Fluorosis, Oral Deseases
12 Month Follow up in Vivo Icon Study on Fluorotic Teeth
Clinical trial to investigate the clinical efficiency of resin infiltration compared to microabrasion in the improvement of dental fluorosis.
- Trial name
- NCT02925780
- Testing
- Resin infiltration, Microabrasion
- Sponsor
- DMG Dental Material Gesellschaft mbH
Mercury Poisoning
NBMI Treatment in Patients With Mercury Toxicity
NBMI (N1, N3-Bis-(2-Mercaptoethyl) Isophthalamide) is a new metal chelator drug proposed as an alternative to the current chelators, and it is widely different; compared to the current chelators, consisting of two cysteamine…
- Trial name
- NBMI-Hg-COL (NCT04183595)
- Testing
- (N1, N3-bis(2- mercaptoethyl)isophthalamide), Excipients microcrystalline cellulose, silica and magnesium stearate
- Where
- Colombia
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- EmeraMed
Ethylene Glycol Poisoning, Methanol Poisoning
Specified Drug-use Survey of Fomepizole Intravenous Infusion (All-case Surveillance)
The objective of this survey is to evaluate the safety and efficacy of fomepizole intravenous infusion in Japanese patients with ethylene glycol and methanol poisonings in daily medical practice.
- Trial name
- NCT02415712
- Testing
- Fomepizole
- Where
- 2 sites in Japan
- Volunteers
- 147 people
- Sponsor
- Takeda
Lead Poisoning
Plan for Testing Fingerstick Bloods on Magellan Systems
This study is to supplement our internal data that demonstrates the continued performance of capillary blood samples on Magellan's lead testing systems: LeadCare II, LeadCare Ultra (which have been cleared previously by FDA), and…
- Trial name
- NCT03256383
- Testing
- Lead testing
- Where
- 3 sites in United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Magellan Diagnostics
Scorpion Envenomation
AScVS and/ or Prazosin for Scorpion Envenomation
The data available for the efficacy of AScVS and prazosin is generated through different trials done in different clinical setting.
- Trial name
- NCT00753064
- Testing
- Antiscorpion venom serum(AScVS)., T.Prazosin, AScVS + Prazosin
- Where
- 5 sites in India
- Volunteers
- 81 people
- Sponsor
- Haffkine Bio-Pharmaceutical Corporation Ltd.
Arachnidism, Latrodectism
The Efficacy and Safety of Aracmyn in Patients With Systemic Latrodectism
The purpose of this study is to compare the safety and effectiveness of an investigational antivenom and the current standard of care (pain management with opioid analgesics) for treating patients with a widow spider bite.
- Trial name
- NCT00247078
- Testing
- widow spider antivenom
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Instituto Bioclon S.A. de C.V.
Snake Bite
Phase 3 Multicenter Comparative Study to Confirm Safety and Effectiveness of the F(ab)2 Antivenom Anavip.
The purpose of this study is to establish if F(ab)2 antivenom (Anavip) is safe for crotalinae envenomation. Confirm its effectiveness in preventing the occurrence of delayed coagulopathies and compare the safety and efficacy with…
- Trial name
- NCT00636116
- Testing
- Crotalinae (pit viper) equine immune F(ab)2, Crotalidae Polyvalent Immune Fab, ovine
- Where
- 18 sites in United States
- Volunteers
- 121 people
- Sponsor
- Instituto Bioclon S.A. de C.V.
Snake Bites, Antivenins
Evaluation of Anti-venoms Serum in Africa
There is little or no assessment under real-use conditions of the efficacy and the tolerance in the short, medium and long term of the antivenoms currently on the market and used in the treatment of snake bites.
- Conditions
- Snake Bites, Antivenins, Snake Venoms
- Trial name
- ESAA (NCT03326492)
- Testing
- Antivenom serum Inoserp Pan-Africa® injection
- Where
- 13 sites in Cameroon
- Volunteers
- 474 people
- Sponsor
- Institut Pasteur
Opioid-related Disorders, Opioid Addiction
ER/LA Opioid Surveillance for Emergency Department Visits and Hospitalizations for Overdose and Poisoning
Study to evaluate the impact of the ER/LA opioid REMS program on the incidence of Emergency Department visits and hospitalizations for overdose/poisoning and death among patients prescribed ER/LA opioid analgesics.
- Conditions
- Opioid-related Disorders, Opioid Addiction, Narcotic Abuse, Drug Abuse
- Trial name
- NCT02866266
- Testing
- Retrospective database review
- Volunteers
- 183,452 people
- Sponsor
- ER/LA Opioid REMS Program Companies (RPC)
Carbon Monoxide Poisoning, Anemia
Utility of Non-invasive Carboxyhemoglobin and Total Hemoglobin Measurement in the Emergency Department
The purpose of this study is to determine the clinical utility of triage screening for anemia and carbon monoxide poisoning (COP) in the ED setting.This is a prospective, nonrandomized, multi-center study of the performance of…
- Trial name
- NCT03017742
- Testing
- Pulse Oximeter
- Where
- Turkey (Türkiye)
- Volunteers
- 813 people
- Sponsor
- Masimo Corporation
Scorpion Sting Envenomation
Double-Blind, Alacramyn® vs. Placebo in Pediatric Patients
There is no FDA approved therapy for the treatment of scorpion envenomation, Centruroides scorpion envenomation produces a pattern of neurotoxicity with a spectrum of severity ranging from trivial to life threatening.
- Trial name
- NCT00685230
- Testing
- Antivenin Centruroides (scorpion) equine immune F(ab)2
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Instituto Bioclon S.A. de C.V.