Clinical trials: Polyethylene Glycols
Short Stature Children Born Small for Gestational Age (SGA)
A Phase II Study of PEG-rhGH Injection for Short Children Born Small for Gestational Age: Efficacy, Safety, and Pharmacokinetics
This study will take place at multiple sites and is divided into three phases:an initial 4-week getting-to-know-you phase,a 26-week main phase where participants receive medication,and a 4-week follow-up phase.Participants will…
- Trial name
- NCT07260500
- Testing
- PEG-rhGH Injection, hGH Injection
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Constipation
Efficacy of Dicopeg Junior in Comparison With Lactulose for the Treatment of Functional Constipation in Children Aged 6 Months to 6 Years.
Assessment of efficacy of Dicopeg Junior, compared to lactulose, in the treatment of functional constipation in children aged 6 months to 6 years.
- Trial name
- NCT03177434
- Testing
- polyethylene glycols (PEG) 3350, Lactulose Oral Product
- Where
- 3 sites in Poland
- Volunteers
- 102 people
- Sponsor
- Children's Memorial Health Institute, Poland
Constipation, Peritoneal Dialysis Complication
Peritoneal Dialysis Pilot Study: Evaluating Polyethylene Glycol (PEG) for Constipation
Constipation is a common condition, which occurs one in four Canadians. Maintaining regular bowel movements is imperative because constipation can affect the quality of PD dialysate flow and result in an unwanted effect on the…
- Trial name
- NCT03148002
- Testing
- Current Bowel Protocol (senna/lactulose), PEG Bowel Protocol (PEG/lactulose)
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Nova Scotia Health Authority
Constipation - Functional, Constipation
A Trial of Actazin Versus PEG 3350 for Maintenance Therapy in Children With Constipation
The goal of this pilot feasibility randomized controlled trial is to determine whether Actazin (kiwifruit extract) is a feasible and effective alternative to polyethylene glycol 3350 (PEG 3350) for maintenance therapy in children…
- Conditions
- Constipation - Functional, Constipation, Constipation Aggravated
- Trial name
- NCT06836024
- Testing
- Actazin chewable tablet, PEG 3350, Chewable Tablet
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Hamilton Health Sciences Corporation
Constipation
Maintenance Treatment for Children With Constipation
Constipation is a common problem among children. The majority of children suffering from constipation have no underlying disease.
- Trial name
- NCT01566409
- Testing
- Polyethylene glycol 3350
- Where
- Denmark
- Volunteers
- 115 people
- Sponsor
- Line Modin
Colonoscopy
The Efficacy Side Effects and the Tolerance of Polyethylene Glycol 3350 as a Bowel Prep in Children
Bowel preparation solutions containing Polyethylene Glycol is a commonly used preparation of the colon for colonoscopy in children.
- Trial name
- NCT01164410
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- The Cleveland Clinic
Chronic Constipation
To Determine the Effect of Forlax® Treatment in Children With Chronic Constipation Who May Also Suffer From Soiling/ Faecal Incontinence.
The purpose of this study is to determine whether Forlax® is more effective than placebo in relieving chronic constipation in children who may also suffer from soiling or faecal incontinence.
- Trial name
- NCT00255372
- Testing
- PEG 4000 (Forlax®)
- Where
- 2 sites in Thailand
- Volunteers
- 88 people
- Sponsor
- Ipsen
Water-Electrolyte Imbalance
Evaluation of One-day Polyethylene Glycol Powder Solution for Colonoscopy in Children
The purpose of this study is to examine the effects of current standard of care Polyethylene Gylcol powder (PEG-P)colonoscopy preparation on a patient's serum electrolytes, tolerance of the prep, and how well the bowel is…
- Trial name
- NCT01626040
- Testing
- polyethylene glycol powder
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Children's Hospital of Philadelphia
Colonoscopy Preparation
PEG Versus PEG+Bisacodyl Versus Sennosides for Colon Cleansing Before Colonoscopy
Background: Polyethylene glycol (PEG) solution has been proven to be effective for large bowel cleansing prior to colonoscopy in children.
- Trial name
- NCT01531140
- Testing
- polyethylene glycol +Bisacodyl, Polyethylene glycol, Sennosides
- Where
- 2 sites in Poland
- Volunteers
- 240 people
- Sponsor
- Medical University of Warsaw
Diabetic Complication, Covid19 Virus Infection
Suspicion of Hypoglycemic Effect of mRNA Based Covid-19 Vaccines (Polyethylene Glycol) Will Happen , Observational Study on Diabetic Patients at Saudia Arabia
vaccines for covid-19 are gold strategy and great achievement at this century for protection against complications of covid-19 , development of many vaccines with different technology represent a big challenge for this disease so…
- Conditions
- Diabetic Complication, Covid19 Virus Infection, Hypoglycemia, Polyethylene Glycol Adverse Reaction
- Trial name
- NCT05087225
- Testing
- polyethelyene glycol
- Where
- Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Saudi Arabia
Constipation
A Study to Compare the Effect of Transipeg 2.95 g or Forlax Junior 4 g in Children With Constipation
The study design combines a long-term safety and a dose range determination objective. The first 8 weeks of the study were primarily intended for the dose range determination, while the later visits were used for the comparison…
- Trial name
- NCT01810653
- Testing
- Macrogol (Transipeg, BAY81-8430), Macrogol (Forlax)
- Where
- 4 sites in Netherlands
- Volunteers
- 97 people
- Sponsor
- Bayer
Child Obesity, Bowel Preparation
Efficacy, Safety and Tolerability of Different Bowel Preparation Before Colonoscopy in Children Over 2 Years Old
Electronic colonoscopy plays an important role in the diagnosis and follow-up of intestinal diseases in children.
- Trial name
- NCT04525560
- Testing
- PEG-ELS-S, PEG-ELS-L
- Where
- China
- Volunteers
- 315 people
- Sponsor
- Children's Hospital of Fudan University
Common Variable Immunodeficiency
Randomized Study of Polyethylene-Glycol-Conjugated Interleukin 2 in Patients With Common Variable Immunodeficiency
OBJECTIVES: I. Determine whether polyethylene-glycol-conjugated interleukin 2 (PEG-IL-2) can reduce the number of infections in patients with common variable immunodeficiency. II.
- Trial name
- NCT00004695
- Testing
- PEG-interleukin-2
- Volunteers
- 48 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Bowel Cleansing Prior to Clinical Procedures
A Study to Investigate Bowel Cleansing With PLENVU® Compared to Sodium Picosulfate in Participants Aged 1 to < 18 Years of Age in Preparation for Colonoscopy
The purpose of the study is to assess the efficacy, safety and tolerability of PLENVU® by measuring its bowel cleansing success rate compared to sodium picosulfate in paediatric participants aged less than 18 years who are…
- Trial name
- CLARITY (NCT07218523)
- Testing
- PLENVU®, Sodium picosulfate
- Where
- 46 sites in Belgium, Croatia and 8 more
- Volunteers
- 212 people
- Sponsor
- Norgine
Colon Cancer
Efficacy of Morning-only Bowel Preparation for Afternoon Colonoscopy.
The study aims to study the adequacy of bowel preparation (colon cleansing) for afternoon colonoscopies. The conventional regimen of giving bowel prep on the evening prior to the day of the colonoscopy will be compared with that…
- Trial name
- CCF (NCT00687830)
- Testing
- Polyethylene Glycol afternoon, Polyethylene Glycol morning
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Cleveland Clinic Florida
Gaucher's Disease
PEG-Glucocerebrosidase for the Treatment of Gaucher Disease
Gaucher disease is a lysosomal storage disease resulting from glucocerebroside accumulation in macrophages due to a genetic deficiency of the enzyme glucocerebrosidase. It may occur in patients of all ages.
- Trial name
- NCT00001410
- Testing
- Lysodase
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- National Institute of Mental Health (NIMH)
Hemolytic Uremic Syndrome, Hemorrhagic Colitis
Study of Repetitive Intestinal Lavage in Patients With EHEC Associated Hemorrhagic Colitis
The investigators examined the outcome of patients with severe Enterohaemorrhagic E. Coli (EHEC) O104:H4 infection suffering from bloody diarrhoea that were at risk to develop hemolytic uremic syndrome and underwent repetitive…
- Conditions
- Hemolytic Uremic Syndrome, Hemorrhagic Colitis, Intestinal Infectious Disease, Intestinal Infection Due to E. Coli
- Trial name
- EHEC-PEG (NCT01561248)
- Testing
- polyethylene glycol solution for daily bowel lavage.
- Where
- Germany
- Volunteers
- 33 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Colonoscopy Preparation
Colon Cleansing Quality of Polyethylene Glycol Compared With Polyethylene Glycol Plus Ascorbic Acid.
The purpose of the study is to assess whether a low volume polyethylene glycol (PEG) plus ascorbic acid based bowel preparation for colonoscopy is not inferior to a large volume polyethylene glycol preparation in subjects with…
- Trial name
- REPREP1 (NCT02073552)
- Testing
- Polyethylene glycol 4000, Macrogol 3350 plus ascorbic acid
- Where
- Spain
- Volunteers
- 472 people
- Sponsor
- Fundación Canaria Rafael Clavijo para la Investigación Biomédica
Colonoscopy
Short Course, Single-dose PEG 3350 for Colonoscopy Prep in Children
The investigators propose to conduct a prospective study of a widely used bowel preparation regimen (polyethylene glycol 3350 + a sports drink) on pediatric patients who undergo a colonoscopy performed by the pediatric…
- Trial name
- NCT01518790
- Testing
- polyethylene glycol 3350
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Walter Reed National Military Medical Center
Constipation
Study Comparing PEG 3350 Laxative to Placebo in the Treatment of Occasional Constipation (Study CL2007-12)(P08216)
Randomized, placebo-controlled, double blind study. 203 subjects entered the study to compare the effect on occasional constipation of polyethylene glycol 3350 to placebo. Subjects took one of study treatments up to 7 days.
- Trial name
- NCT00770432
- Testing
- Polyethylene glycol 3350
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Bayer