Clinical trials: Polyhandicap
Polyhandicap
Intensive Psychomotor Rehabilitation on Cognitive Motor Abilities and Adaptive Capacity on Children With Polyhandicap
Primary objective of the study is to compare and evaluate the impact of intensive care of rehabilitation of psychomotor vs. the standard care on adaptive behaviour of children with polyhandicap at 12 months after randomization.
- Trial name
- REEDUC-PLH (NCT04280458)
- Testing
- Intentive rehabilitation, Routine care
- Where
- France
- Volunteers
- 62 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Respiratory Decompensation, Multiple Disabilities
Long-term Use of Intrapulmonary Percussive Ventilation for Preventing Hospitalizations Due to Respiratory Decompensation in Children With Multiple Disabilities
Chronic respiratory failure is the leading cause of morbidity and mortality in children with multiple disabilities. Musculoskeletal disorders, swallowing disorders and ventilatory control abnormalities lead to progressive…
- Trial name
- PERKINE (NCT07473856)
- Testing
- Intrapulmonary Percussive Ventilation IPV
- Where
- France
- Volunteers
- 146 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Polyhandicap
Family Impact of Polyhandicap: a Mixed Methodological Approach
Polyhandicap (PLH) is a complex disability condition corresponding to a chronic affliction occurring in an immature brain, leading to the combination of profound mental retardation and serious motor deficit, resulting in an…
- Trial name
- PolyMiMe (NCT04492761)
- Testing
- qualitative study
- Where
- France
- Volunteers
- 260 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Polyhandicap, Behavior Disorders
Impact of an Intensive Multimodal Educative Program on Behavioral Disorders of Patients With Profound Multiple Disabilities and on the Quality of Life and Feelings of Caregivers
Profound multiple disabilities also called in French polyhandicap are defined by the combination of a deep mental disability and severe motor deficit with extreme restriction of autonomy.
- Trial name
- TDCHandi (NCT02510846)
- Testing
- Intensive educative management
- Where
- France
- Volunteers
- 63 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Polyhandicap
Third Wave of the EVAL-PLH (POLYhandicap) Cohort: New Eyes
The general objective of the EVAL-PolyNE project is to improve the representativeness of the EVAL-PLH cohort by broadening participation in the John Bost Foundation, due to its geographical particularity and its private valence.
- Trial name
- EVAL-POLYNE (NCT06811441)
- Where
- 6 sites in France
- Volunteers
- 1,102 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille