Clinical trials: Polyp of Large Intestine
Colorectal Cancer
Real-Time Characterizations of Diminutive Colorectal Polyps Using Narrow Band Imaging
Colorectal cancer is the second leading cause of cancer related death in the United States. Colonoscopy is the most commonly performed screening procedure and diminutive polyps (<5mm) are the most commonly found polyps during…
- Trial name
- NCT02441998
- Testing
- Education intervention: Training in Narrow Band Imaging
- Volunteers
- 26 people
- Sponsor
- University of Michigan
Colorectal Adenoma, Colorectal Cancer Control and Prevention
6-year Follow-up Data After the Berberine Intervention Trial
Colorectal cancer (CRC) is a common malignancy of the digestive tract, which constitutes a major public health burden. Almost 90% of CRC cases progress from precursor adenomatous polyps through adenoma-carcinoma sequence.
- Conditions
- Colorectal Adenoma, Colorectal Cancer Control and Prevention, Colorectal Polyps
- Trial name
- NCT06629051
- Testing
- Berberine Hydrochloride
- Where
- China
- Volunteers
- 891 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Colorectal Cancer
Aspirin and/or Folic Acid in Preventing Recurrent Colorectal Polyps
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of aspirin and/or folic acid may be effective in preventing recurrent polyps in patients who have…
- Trial name
- NCT00033319
- Testing
- folic acid, acetylsalicylic acid
- Where
- 32 sites in United Kingdom
- Sponsor
- Queen's Medical Center
Colorectal Neoplasms
Artificial Intelligence for Diminutive Polyp Characterization
Artificial intelligence is a promising tool that may have a role in characterizing colon epithelial lesions (CADx), helping to get a reliable optical diagnosis regardless of the endoscopist experience.
- Trial name
- NCT05391477
- Testing
- GI-Genius artificial intelligence
- Where
- Spain
- Volunteers
- 643 people
- Sponsor
- Hospital Universitario La Fe
Colorectal Adenoma, Colorectal Polyp
EndoRings Colonoscopy vs Standard Colonoscopy
The study aims to compare the results between a standard colonoscopy to a colonoscopy with an attachment on the distal end of the colonoscope.
- Conditions
- Colorectal Adenoma, Colorectal Polyp, Colon Cancer
- Trial name
- NCT03418662
- Testing
- EndoRings device
- Where
- United States
- Volunteers
- 592 people, healthy volunteers welcome
- Sponsor
- Indiana University
Colorectal Polyposis
Multicenter Study on the Pathogenic Germline Gene Variants of Colorectal Polyposis in China
Patients suspected of adenomatous polyposis were included. The criteria used were more than 10 polyps observed under colonoscopy, and pathological confirmation of adenoma. Clinical data and pedigree information were collected.
- Trial name
- NCT04961125
- Testing
- germline variants
- Where
- 5 sites in China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Colorectal Polyp, Colorectal Neoplasms
Real-time AI-assisted Endocyroscopy for the Diagnosis of Colorectal Lesions
Colorectal cancer (CRC) is the third most common malignancy and the second leading cause of cancer-related death worldwide. Colonoscopy is considered the preferred method of screening for colorectal cancer, and early and…
- Trial name
- NCT06791395
- Testing
- Computer-aided diagnosis (CADx) support tool
- Where
- 3 sites in China
- Volunteers
- 570 people
- Sponsor
- The First Hospital of Jilin University
Colon Cancer, Diverticulitis
General Surgical Outcomes Quality Improvement Database (UH-SOCRATES)
A database has been established to track the outcomes of all cases performed in the University Hospitals Department of Surgery in an effort to improve quality of surgical performance and case management.
- Conditions
- Colon Cancer, Diverticulitis, Colorectal Polyps, Crohn's Disease
- Trial name
- SOCRATES (NCT00622557)
- Where
- United States
- Volunteers
- 200,000 people
- Sponsor
- University Hospitals Cleveland Medical Center
Colorectal Polyp
The Accuracy of Human Endoscopic Detection of Submucosal Invasive Cancer in Colorectal Polyps
Colorectal cancer (CRC) is a leading cause of death in the Western world. It can be effectively prevented by removal of pre-malignant polyps (polypectomy) during colonoscopy.
- Trial name
- NCT05191095
- Where
- Belgium
- Volunteers
- 82 people
- Sponsor
- University Hospital, Ghent
Colorectal Polyp
Prediction of Diminutive/Small Polyp Histology: Didactic vs. Computer-based Training
Bowel cancer is one of the most common cancers and the best method of diagnosing it is through endoscopic examination of the bowel (colonoscopy).
- Trial name
- NCT03843567
- Testing
- Endoscopic characterisation training
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Colorectal Polyp, Linked Color Imaging
Computer-assisted Diagnosis System Based on Linked Colour Imaging
Linked color imaging (LCI)，a new endoscopy modality, creates clear and bright images by using short wavelength narrow band laser light. LCI can make red area appear redder and white areas appear whiter.
- Conditions
- Colorectal Polyp, Linked Color Imaging, Computer-aided Diagnosis
- Trial name
- NCT03359343
- Where
- 2 sites in China
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Colon Polyp
NBI-NearFocus Assisted Cold Snare Polypectomy Improves the Complete Resection Rate of Small Colorectal Polyps: a Prospective Single-arm Observational Study
NBI-NearFocus can assist cold snare polypectomy (CSP) to remove small colorectal polyps, but its specific efficacy is not clear.The aim of this study was to assess the efficacy of CSP with NBI-NearFocus evaluation of polypectomy…
- Trial name
- NCT06601426
- Testing
- CSP
- Where
- China
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Qianfoshan Hospital
Colorectal Polyp, Colonic Neoplasms
Online Education Module to Accurately Classify Polyp Size
Investigators developed an online educational module (ESTIMATE) to teach Gastroenterology (GI) trainees how to estimate polyp size using a snare.
- Trial name
- ESTIMATE (NCT05846295)
- Testing
- ESTIMATE
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Colorado, Denver
Colon Polyps
Prospective Study of Colonoscopic Resection of Large Polyps and Flat Lesions
With this study, the investigators plan to review the performance of colonoscopic resection of large (> 1 cm) and flat lesions in the colon.
- Trial name
- NCT02332772
- Testing
- Data Collection
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Adenoma of Large Intestine
Folic Acid in Preventing Colorectal Polyps in Patients With Previous Colorectal Polyps
RATIONALE: Chemoprevention is the use of certain substances to keep cancer from forming. The use of folic acid may prevent colorectal cancer.
- Trial name
- NCT00512850
- Testing
- Folic acid
- Volunteers
- 672 people
- Sponsor
- Brigham and Women's Hospital
Colorectal Polyp
Clinical Study on the Accuracy of Real-time AI-assisted Endocytoscopy in the Diagnosis of Colorectal Diminutive Polyps
Colorectal cancer (CRC) is the third most common malignant tumor in the world and the second largest cause of cancer-related death [1].
- Trial name
- NCT06791408
- Where
- China
- Volunteers
- 600 people
- Sponsor
- The First Hospital of Jilin University