Clinical trials: Polyunsaturated Fatty Acids
Type 2 Diabetes Mellitus
Lipid, Glycemic, and Insulin Responses to Meals Rich in Different Fatty Acids
A meal rich in very-long chain omega-3 fatty acids or oleic acid may lower postprandial insulin levels in comparison to a meal rich in linoleic acid or palmitic acid.
- Trial name
- NCT00479791
- Testing
- Test meals rich in different fatty acids
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Texas Southwestern Medical Center
Severe Acute Malnutrition
Feeding Malnourished Children Different Types of Fatty Acids to Promote Neurocognitive Development
An appropriate balance of omega-6 and omega-3 fatty acids is important for support of neurocognitive development in healthy infants and toddlers.
- Trial name
- NCT03094247
- Testing
- Amoxicillin, HO-RUTF, D-HO-RUTF
- Where
- Malawi
- Volunteers
- 2,897 people
- Sponsor
- Washington University School of Medicine
Allergies
Does Omega-3 Fatty Acid Supplementation in Pregnancy and During Lactation Protect the Child From Allergic Disease?
The incidence of allergic diseases has increased and a relation between allergy and dietary fatty acids has been proposed. Modulation of the maternal immune function during pregnancy may have an impact on future clinical outcomes…
- Trial name
- NCT00892684
- Testing
- Omega-3 long chain polyunsaturated fatty acids
- Where
- Sweden
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Acute Lymphoblastic Leukemia, Malnutrition
Effect of Enteral Docosahexaenoic Acid Administration in Children With Acute Lymphoblastic Leukemia
The purpose of this study is to evaluate if enteral docosahexaenoic acid (DHA) administration during the first three months of treatment reduces the deterioration of nutritional status, treatment toxicity and early mortality in…
- Trial name
- DHA-ALL (NCT01051154)
- Testing
- Docosahexaenoic acid (DHA)
- Where
- Mexico
- Volunteers
- 72 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
22q11 Deletion Syndrome
Indicated Prevention With Long-chain Polyunsaturated Omega-3 Fatty Acids in Patients With 22q11 Microdeletion Syndrome.
The purpose of the present trial is to investigate the effects of omega-3 PUFAs in individuals aged 12-26 years with 22q11DS at ultra-high risk for developing a first episode of psychosis.
- Trial name
- NCT02070211
- Testing
- omega-3 PUFAs, Standard care
- Where
- Holy See
- Volunteers
- 80 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Microbial Colonization, Infant Development
The Effects of Omega-3 PUFAs on the Infant Microbiome and Immunity
Prenatal supplementation with fish oil, rich in omega-3 polyunsaturated fatty acids, is widely recommended in Canada. The aim of this observational, prospective cohort study is to determine the effects of maternal fish oil…
- Trial name
- NCT03297801
- Testing
- Fish oil supplements
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Migraine
Omega-3 Supplementation for Pediatric Migraine
The purpose of the study is to assess the biochemical and clinical effects of omega-3 polyunsaturated fatty acid (PUFA) supplementation in youth suffering from migraine, including its effects on migraine disability, psychological…
- Trial name
- NCT06899074
- Testing
- Omega 3 Polyunsaturated Fats
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of North Carolina, Chapel Hill
Fatty Acid Status
Polyunsaturated Fatty Acids in Child Nutrition
Primary objective of this study is to examine the effects of 2 different approaches of dietary strategies to optimise fatty acid composition in complementary food on infant's fatty acid status and its consequences on cognitive…
- Trial name
- PINGU (NCT01487889)
- Testing
- Fatty acid composition of complementary food
- Where
- Germany
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Research Institute of Child Nutrition, Dortmund
Preterm Birth, Child Development
Omega Tots: A Randomized, Controlled Trial of Long-chain Polyunsaturated Fatty Acid Supplementation of Toddler Diets and Developmental Outcomes
The purpose of this study is to examine whether supplementation with certain polyunsaturated fatty acids can help the cognitive development of children born preterm.
- Trial name
- NCT01576783
- Testing
- Docosahexaenoic Acid + Arachidonic Acid (DHA+AA)
- Where
- United States
- Volunteers
- 377 people
- Sponsor
- Sarah Keim
Severe Acute Malnutrition
A Trial of n-3 PUFA-Enriched Ready to Use Therapeutic Food for Childhood Severe Malnutrition
The investigators will perform a randomised controlled trial of the provision of food designed for rehabilitation of malnourished children that is supplemented with n-3 fatty acids compared to usual composition.
- Trial name
- Njugu Plus (NCT01593969)
- Testing
- RUTF/Flax Oil, RUTF/Flax Oil plus additional Fish Oil, Standard RUTF
- Where
- Kenya
- Volunteers
- 60 people
- Sponsor
- University of Oxford
Infant Development
Effect of Long-Chain Polyunsaturated Fatty Acid Supplementation on Toddler Cognition
The hypothesis to be examined is that dietary LCP-supplementation in the second and third years of life will improve cognitive and visual maturation in early childhood.
- Trial name
- NCT00982462
- Testing
- Docosahexaenoic acid (DHA) and arachidonic acid (ARA)
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Retina Foundation of the Southwest
Healthy
The Effect of Long-Chain Polyunsaturated Fatty Acids on Cognitive Performance and Mood
The study investigates whether dietary intake of omega-3 long-chain polyunsaturated fatty acids affects learning and mood of healthy young adults.
- Trial name
- NCT00615277
- Testing
- Omega-3 fatty acids
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Attention-Deficit/Hyperactivity Disorder
Supplementation of Phosphatidylserine (PS) and n-3 Long Chain Fatty Acids (EPA, DHA) in Children With ADHD
To determine whether supplementation of omega-3 long-chain polyunsaturated fatty acid conjugated to phosphatidylserine rather than triglycerides (fish oil) could affect Attention-deficit/hyperactivity disorder symptoms in…
- Trial name
- NCT00382616
- Testing
- Phosphatidylserine-Omega3
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Acute Lymphoblastic Leukemia, Vitamin d Deficiency
Effect of Supplementation With ω-3 Fatty Acids, Vitamin D and Calcium in Patients With Acute Lymphoblastic Leukemia.
The purpose of this study is to evaluate the efficacy of supplementation with Omega 3, Vitamin D and Calcium, in a cohort of children with ALL undergoing treatment and compare changes in the concentrations of biomarkers of bone…
- Trial name
- NCT05950204
- Testing
- ω-3 polyunsaturated fatty acids (DHA and EPA), Vitamin D (cholecalciferol), Calcium (calcium carbonate)
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Cystic Fibrosis
Omega 3 Supplementation in Cystic Fibrosis Patients
Essential fatty acids (EFA) deficiency has been often reported in patients with cystic fibrosis (CF), particularly in those homozygous for the DF508 mutation.
- Trial name
- NCT00959010
- Testing
- omega-3 triglycerides
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Queen Fabiola Children's University Hospital
Healthy First Degree Relatives of Crohn's Disease Patients
Prebiotics and Diet to Reduce "Leaky" Gut in First Degree Relatives of Crohn's Disease Patients
Crohn's disease (CD) is a recurring inflammation of the intestines. The etiology is unknown; however evidence suggests that it could be a combination of gut microbes, environmental factors and genetics.
- Trial name
- NCT03950336
- Testing
- Prebiotics, Low n-6 PUFA Diet, Maltodextrin
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- University of Alberta
Attention Deficit Disorder With Hyperactivity, ADHD Inattention or Mixed Type
Efficacy of Phosphatidylserine Enriched With n-3 PUFA Supplementation on ADHD in Children With Epilepsy
Our project aims to develop a new therapeutic approach in epilepsy-associated attention disorders in children, through evaluation of the clinical impact of dietary n-3 fatty acids, containing eicosapentaenoic acid (EPA) and…
- Conditions
- Attention Deficit Disorder With Hyperactivity, ADHD Inattention or Mixed Type, Epilepsy, Child
- Trial name
- AGPIn3 (NCT02348073)
- Testing
- Vayarin®, supplementation of n-3 PUFA
- Where
- 13 sites in France
- Volunteers
- 77 people
- Sponsor
- Hospices Civils de Lyon
ADHD
Supplementation of Polyunsaturated Fatty Acids in Children With Attention Deficit/Hyperactivity Disorder (ADHD)
The purpose of the study is assessing the efficacy of Omega - 3 and Omega - 6 treatment in boys with Attention-Deficit/Hyperactivity Disorder (ADHD) compared with control group healthy boys.
- Trial name
- NCT02114632
- Testing
- Eye Q
- Where
- Poland
- Volunteers
- 89 people
- Sponsor
- Medical University of Warsaw
Food Allergy, Eczema
Treatment of IgE Associated Eczema With Omega-3 Long Chain Polyunsaturated Fatty Acids in Infancy and the Development of Bronchial Asthma in Childhood
Although some causal factors in allergy development such as allergen exposure and environmental pollution have decreased during recent years, the incidence of the allergic diseases has increased in the Western world.
- Conditions
- Food Allergy, Eczema, Sensitisation
- Trial name
- Omega-Treat (NCT01473823)
- Testing
- Omega-3 LCPUFA
- Where
- Sweden
- Volunteers
- 160 people
- Sponsor
- Ostergotland County Council, Sweden
Attention Deficit Hyperactivity Disorder
Effect of Long Chain Polyunsaturated Fatty Acids on Behavior and Cognition in Children With Attention Deficit Hyperactivity Disorder
The study investigates whether eicosapentaenoic/docosahexaenoic acid supplementation affects behavior and cognition in children with attention deficit hyperactivity disorder.
- Trial name
- EFA (NCT01055119)
- Testing
- Omega-3 fatty acids
- Where
- 2 sites in Germany
- Volunteers
- 95 people
- Sponsor
- University of Ulm