Clinical trials: Poor Nutrition
Faltering Growth, Failure to Thrive
Leveraging Optimal Tolerance in Undernourished Infants to Support Growth
The goal of this study is to learn if InfaCore (IC) an energy and nutrient dense formulation (ENDF) can improve growth and tolerance in infants with or at risk of growth faltering when fed IC.
- Trial name
- LOTUS (NCT07549360)
- Testing
- Infant Formula
- Where
- Thailand
- Volunteers
- 35 people
- Sponsor
- Dutch Medical Food
Postmenopausal Osteoporosis, Postmenopause
Frequency of Hyperparathyroidism in Postmenopausal Osteoporosis and Its Treatment
Recently, an increase in the prevalence of hyperparathyroidism and hypovitaminosis D in postmenopause women has been occurring in Mexico and the world.
- Conditions
- Postmenopausal Osteoporosis, Postmenopause, Hyperparathyroidism, Secondary, Hypovitaminosis D
- Trial name
- NCT05347082
- Testing
- Cholecalciferol
- Where
- Mexico
- Volunteers
- 47 people
- Sponsor
- Hospital Regional 1o de Octubre
Knee Osteoarthritis, Vitamin D Deficiency
Prospective, Assessment of Vitamin D and Calcium Supplementation, Improvement of Nutritional Status and Preoperative Rehabilitation in Patients Before Knee Arthroplasty.
Prospective randomized study of 150 patients qualified for knee arthroplasty between 2015 and 2017. Patients were randomized into 3 groups receiving vitamin D and calcium supplementation, increased protein supply and preoperative…
- Conditions
- Knee Osteoarthritis, Vitamin D Deficiency, Pain, Postoperative, Arthropathy of Knee
- Trial name
- NCT04291833
- Testing
- Intervention group 1, Intervention group 2, Control group 0
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Jagiellonian University
X-Linked Hypophosphatemia
Study of the Safety, Pharmacodynamics (PD) and Efficacy of KRN23 in Children From 1 to 4 Years Old With X-linked Hypophosphatemia (XLH)
The primary objectives of the study are to: Establish the safety profile of KRN23 for the treatment of XLH in children between 1 and 4 years old Determine the PD effects of KRN23 treatment on serum phosphorus and other PD markers…
- Trial name
- NCT02750618
- Testing
- Burosumab
- Where
- 3 sites in United States
- Volunteers
- 13 people
- Sponsor
- Kyowa Kirin, Inc.
Appetite Loss
Effectiveness of Cyproheptadine Hydrochloride Against Appetite to Improve Children's Nutritional Status
The goal of this clinical trial is to learn about the benefits of Cyproheptadine hydrochloride in increasing appetite as well as its effect on weight gain in children aged 1-5 years who have difficulty eating.
- Trial name
- NCT07006181
- Testing
- cyproheptadine hydrochloride
- Where
- Indonesia
- Volunteers
- 44 people
- Sponsor
- Universitas Indonesia
Pregnancy, Moderate Malnutrition
Interventions for Moderate Malnutrition in Pregnancy
Malnutrition during pregnancy is more common in poor women in the developing world due to inadequate dietary intake combined with increased nutrient requirements; pregnancy risk is more consequential than among other demographic…
- Trial name
- Mamachiponde (NCT02120599)
- Testing
- ready-to-use supplementary food, corn-soy blend, iron
- Where
- 2 sites in Malawi
- Volunteers
- 1,867 people
- Sponsor
- Washington University School of Medicine
Down Syndrome, Vitamin D Deficiency
Effect of Exercise Intensity on Vitamin D
Children with Down's syndrome (DS) are more liable to vitamin D deficiency. Treating this deficiency with supplements is associated with the risk of intoxication due to increased intestinal absorption or decreased vitamin D…
- Trial name
- NCT05024110
- Testing
- High intensity treamill exercise training., Moderate intensity treamill exercise training.
- Where
- Saudi Arabia
- Volunteers
- 44 people
- Sponsor
- Taif University
Severe Acute Malnutrition
Evaluating RISQ System Implementation in Acutely Malnourished Children in Chad (CRIMSON)
The purpose of this study is to evaluate the effect of the Responses to Illness Severity Quantification (RISQ) system implementation on mortality and processes of care in a nutritional program treating children 6 to 59 months of…
- Trial name
- CRIMSON (NCT06123390)
- Testing
- The Responses to Illness Severity Quantification (RISQ) System
- Where
- Chad
- Volunteers
- 14,671 people
- Sponsor
- The Hospital for Sick Children
Executive Function Disorder, Emotional Regulation
Evaluation of Executive Function and Emotional Regulation in Children in Bangladesh
The study explores the impact of malnutrition at enrollment on executive function (EF) and emotional regulation (ER) in malnourished 1-year-old children and whether specially designed brain directed therapeutic feeds improve…
- Conditions
- Executive Function Disorder, Emotional Regulation, Malnutrition, Child
- Trial name
- NCT05629624
- Testing
- Chickpea based RUSF, E-RUSF, Outcome reference group/RUSF
- Where
- Bangladesh
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Healthy, Deficiency Disease
Effects of Dietary Carbohydrate and Fat on Hormones
This study will try to determine if intake of dietary fats or carbohydrates influences the tendency to gain weight or accumulate body fat.
- Trial name
- NCT00016848
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Nutrition Disorder, Child, Nutrition Disorders in Adolescence
Health and Nutrition Survey on Shenzhen Children
1. Master and analyze the nutritional health, growth and development status of primary and secondary school students in Shenzhen, and discover the main nutritional health, growth and development problems and influencing factors.
- Conditions
- Nutrition Disorder, Child, Nutrition Disorders in Adolescence, Nutritional Deficiency, Nutrition, Healthy
- Trial name
- NCT05244785
- Where
- China
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Shenzhen Center for Chronic Disease Control
Arrest of Bone Development or Growth, Constitutional Delay of Growth and Puberty
YoUng Adolescents' behaViour, musculoskeletAl heAlth, Growth & Nutrition
More children will survive to adulthood today than at any other point in human history, as evidenced by the proportion of live births and absolute numbers.
- Conditions
- Arrest of Bone Development or Growth, Constitutional Delay of Growth and Puberty, Malnutrition, Child, Gestational Diabetes
- Trial name
- YUVAAN (NCT05603793)
- Testing
- Knowledge, Attitude & Practices
- Where
- India
- Volunteers
- 1,304 people, healthy volunteers welcome
- Sponsor
- Hirabai Cowasji Jehangir Medical Research Institute
Undernutrition
Nutritional Support for Lactating Women and Azithromycin to Infants - Mumta Lactating Women Trial
A community-based, randomized control, assessor blinded trial in peri-urban settings of Karachi, Pakistan to study the impact of Lipid-based Nutritional Supplement for Pregnant and Lactating women which is balanced energy-protein…
- Trial name
- MumtaLW (NCT03564652)
- Testing
- Balanced energy-protein (BEP), Azithromycin
- Where
- Pakistan
- Volunteers
- 957 people, healthy volunteers welcome
- Sponsor
- Vital Pakistan Trust
Vitamin D Deficiency, Thoracic Surgery
Prevention of Vitamin D Deficiency Following Pediatric CHD Surgery: a Phase II Dose Evaluation Randomized Controlled Trial Comparing Usual Care With a High Dose Pre-operative Supplementation Regimen Based on the Institute of Medicine Daily Upper Tolerable Intake Level
Our research group has shown that almost all children with congenital heart disease (CHD) are vitamin D deficient following heart surgery.
- Conditions
- Vitamin D Deficiency, Thoracic Surgery, Pediatric Disorders, Heart Defects, Congenital
- Trial name
- HICCUPS 2 (NCT01838447)
- Testing
- Cholecalciferol
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- Children's Hospital of Eastern Ontario
Undernutrition
Effects of Oral Nutritional Supplementation in Children at Risk of Undernutrition
This prospective, randomized, controlled study will evaluate the effects of oral nutritional supplementation plus dietary counseling versus dietary counseling alone in children at nutritional risk.
- Trial name
- NCT05239208
- Testing
- Oral Nutrition Supplement (ONS) Group, Control Group
- Where
- Vietnam
- Volunteers
- 330 people
- Sponsor
- Abbott Nutrition
Child Malnutrition
Parental Misperceptions on Child Nutrition in India: Implications for Child Feeding Practices and Growth
The goal of this randomized controlled trial is to examine the role of parental misperceptions and information gaps in contributing to poor child dietary practices and high child undernutrition rates in India.
- Trial name
- NCT06473025
- Testing
- Information on Relative Nutritional Status, Information on Returns to Child Nutrition
- Where
- India
- Volunteers
- 1,542 people
- Sponsor
- University of Southern California
Obesity
Reducing Health Disparities in Childhood Obesity
In this study, we will address cost barriers to participating in summer programs and hypothesize this will lead to marked improvements in children's obesogenic behaviors and a reduction in excessive, unhealthy weight gain over…
- Trial name
- NCT04072549
- Testing
- Free Summer Programming
- Where
- 2 sites in United States
- Volunteers
- 651 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Mild Cognitive Impairment, Alzheimers Disease
Multiple Nutritional Deficiencies Causing Dementia of the Alzheimer Type
The purpose of the study is to compare the concentrations of Vitamin B1 (thiamine), Vitamin B6 (pyridoxal-5-phosphate), folate, Vitamin B12 (cobalamin), Vitamin C (ascorbic acid), Vitamin A (retinol), Vitamin E (alfa-tocopherol)…
- Trial name
- ALZ-vit (NCT01479855)
- Where
- Norway
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Underweight, Wasting
Preventing Infant Malnutrition With Early Supplementation
Background: Worldwide, more than 50 million children under 5 years of age are wasted (weight-for-length/height Z-score (WLZ) <-2) and over 150 million children under 5 are stunted (length/height-for-age Z-score (LAZ) <-2); such…
- Conditions
- Underweight, Wasting, Stunting, Breastfeeding
- Trial name
- PRIMES (NCT04704076)
- Testing
- ESVS, Exclusive breastfeeding
- Where
- 2 sites in Guinea-Bissau, Uganda
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Vitamin B12 Deficiency
Vitamin Deficiencies and Suppletion in Morbid Obesity
The purpose of this study is to evaluate the most effective treatment for patients who underwent a Roux-en-Y gastric bypass and developed postoperatively a vitamin B12 deficiency.
- Trial name
- NCT02270749
- Testing
- Hydroxocobalamin, FitForMe vitamin B12
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Rijnstate Hospital
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