Clinical trials: Population Medicine
Acne Vulgaris
Generic Tazarotene Cream, 0.1% in the Treatment of Acne Vulgaris
To compare the safety and efficacy profiles of Tazarotene Cream, 0.1 % to the reference listed drug Tazorac® (tazarotene) Cream, 0.1 % in order to demonstrate bioequivalence, and to demonstrate superiority of the 2 active creams…
- Trial name
- NCT02160678
- Testing
- Vehicle, Tazarotene Cream, 0.1 %, Tazorac Cream, 0.1%
- Where
- United States
- Volunteers
- 1,741 people, healthy volunteers welcome
- Sponsor
- G & W Laboratories Inc.
pH
The Impact of Anti- Asthmatic Medications on Salivary pH and Dental Caries Pattern in a Group of Egyptian Children With Bronchial Asthma
The impact of Anti- Asthmatic medications on salivary pH and dental caries pattern in a Group of Egyptian Children with Bronchial Asthma.
- Trial name
- NCT03877874
- Testing
- Aironyl syrup(Terbutaline sulfate) + Epidrone syrup(Dexamethone)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Cairo University
SARS-CoV Infection
Comparison of Strategies Based on RT-PCR or Antigenic Test for the Screening of SARS-CoV-2 Infection (COVID-19).
The virological diagnosis of SARS-CoV-2 infection is pivotal for the control of the outbreak by large screening of a- or pauci-symptomatic subjects.
- Trial name
- AutoCoV (NCT04859023)
- Testing
- saliva sample combined to an anterior nare self-swabbing (Self-samples), saliva sample (Self-sample), Survey of SARS-COV-19 knowledge
- Where
- France
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Acupuncture Therapy, Sports Medicine
Acupuncture in Adolescent Football Players
Is it feasible to perform acupuncture in the training field after sport performance in adolescent football players? Does acupuncture provide a decrease in muscle soreness and improvement in overall sense of well-being in the…
- Trial name
- NCT03478800
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Atrial Fibrillation, Coronary Heart Disease
EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality
Health inequality and genetic disparity are a significant issue in the United Kingdom (UK). This study focuses on diseases that are associated with significant morbidity and mortality in the UK, and specifically examines the…
- Conditions
- Atrial Fibrillation, Coronary Heart Disease, Cardiovascular Diseases, Heart Failure
- Trial name
- EMPOWER (NCT03987633)
- Where
- United Kingdom
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Future Genetics Limited
Preventive Medicine
Clinical Trial of Anaferon for Children Efficacy in Prevention of Influenza and Other ARVI
The objective of this study is to obtain additional data on the efficacy and safety of 12-week course of therapy with Anaferon for children for prevention of influenza and other acute respiratory viral infections in children…
- Trial name
- NCT03301155
- Testing
- Anaferon for children
- Where
- 33 sites in Russia, Uzbekistan
- Volunteers
- 1,036 people, healthy volunteers welcome
- Sponsor
- Materia Medica Holding
HIV/AIDS, Adolescent Behavior
Youth Power Action Feasibility Study of Online Support Group Intervention Among Adolescents Living With HIV in Nigeria
This study will examine the feasibility and acceptability of an intervention designed to improve retention in HIV care services and improve anti-retroviral therapy (ART) adherence among adolescents ages 15-19 years living with…
- Conditions
- HIV/AIDS, Adolescent Behavior, Medication Adherence, Health Behavior
- Trial name
- NCT03076996
- Testing
- Online support group
- Where
- Nigeria
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- FHI 360
Pemphigus, Bullous Pemphigoid
Human Leukocyte Antigen Class II (DRB1 and DQB1) Alleles and Haplotypes Frequencies in Patients With Pemphigus Vulgaris Among the Russian Population
Pemphigus is a rare autoimmune life-threatening blistering condition affecting skin and mucous membranes. Pemphigus belongs to a family of polygenic disorders.
- Conditions
- Pemphigus, Bullous Pemphigoid, Stevens-Johnson Syndrome, Toxic Epidermal Necrolyses
- Trial name
- NCT05284929
- Testing
- A single blood sample for HLA typing
- Where
- Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sechenov University
Adult Cancer Survivors, Adult Cancer Patients
Holistic Evaluation of Approaches to Long-term Health & Survivorship
This study aims at investigating behaviors of cancer patient regarding complementary and alternative medicine (CAM) with mixed methodology.
- Trial name
- HEALTHS (NCT07745205)
- Testing
- Interventional mixed-methods evaluation of cancer patient's behaviour regarding CAMs (focus groups), Quantitative evaluation of cancer patient's use of CAM's
- Where
- Belgium
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Jules Bordet Institute
Malaria
Monitoring Pregnant Women for Antimalarial Drug Resistance
Annually, malaria affects an estimated 229 million people, causing 409,000 deaths (WHO 2019) mostly in Africa. Despite a substantial decline in malaria-related maternal and child deaths in recent years, progress in controlling…
- Trial name
- MIRANDA (NCT05072613)
- Testing
- Malaria screening
- Where
- Democratic Republic of the Congo
- Volunteers
- 6,833 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Prematurity
Effect of Osteopathic Manipulative Treatment on Length of Stay in Preterms
The use of osteopathic manipulative treatment (OMT) in preterm infants has been documented and results from previous studies suggest the association between OMT and length of stay (LOS) reduction, as well as significant…
- Trial name
- NCT01544257
- Testing
- osteopathic manipulative treatment, Usual care
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- European Institute for Evidence Based Osteopathic Medicine
Cell Physiology Education
RGE-Based Cell Physiology Education for International Medical Students
This study evaluated an integrated active-learning approach for teaching cell physiology to international medical students at Tehran University of Medical Sciences.
- Trial name
- NCT07885553
- Testing
- RGE-Based Cell Physiology Education
- Where
- Iran
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Plasmodium Falciparum Malaria, Plasmodium Vivax Malaria
Targeting High Risk Populations With Enhanced Reactive Focal Mass Drug Administration in Thailand
This study assesses the effectiveness of reactive focal mass drug administration (rfMDA), targeting both village and forest working populations, compared to control for reducing the health promotion hospital-level (sub-district)…
- Trial name
- COMBAT (NCT05052502)
- Testing
- Case Management and Follow-up, Reactive focal mass drug administration (rfMDA)
- Where
- Thailand
- Volunteers
- 14,977 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pain, Drug Effect
Development of a Morphine Pharmacokinetic and Pharmacodynamic Model for the Neonatal Population
This research aims to study what the baby's body does with morphine and how morphine works in the baby's body. One hundred newborn babies will be enrolled in this study.
- Trial name
- NCT03035578
- Testing
- Morphine
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Anxiety
Intranasal Dexmedetomidine Versus Oral Paracetamol as a Pre-anaesthetic Medication in Pediatric Age Group
Pre-operative anxiety is a major problem in children because it produces undesired results on induction and postoperative outcome. Dexmedetomidine is a highly specific alpha 2 adrenergic receptor agonist.
- Trial name
- NCT04949477
- Testing
- Dexmedetomidine, paracetamol
- Where
- Egypt
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Benha University
For New York State Registered Family Practitioners and Internal Medicine Physicians
Community Primary Care Providers to Implement and Disseminate Cancer Prevention Interventions for Latino Populations
The purpose of this study is to understand primary care provider's knowledge, attitudes, and barriers to promoting evidence-based cancer screening and prevention practices for physicians with large Latino patient populations.
- Trial name
- NCT01803750
- Testing
- in-depth, semi-structured interviews
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Other Conditions That May Be A Focus of Clinical Attention
Effectiveness of Buddhist Intergrated Group Intervention on Minefulness in Adolescents
The pupose of the study is to determine the effectiveness of the Buddhist integrated group intervention improve the mindfulness in adolescents by a randomized controlled trial.The study divede the adolescents in two groups group…
- Trial name
- NCT01605604
- Testing
- buddhist mind fullness
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Laceration of Skin, Anxiety
IN Midazolam vs IN Dexmedetomidine vs IN Ketamine During Minimal Procedures in Pediatric ED
Pain in young children has been universally under-recognized due to their inability to describe or localize pain. Improvements in pharmacological interventions are necessary to optimize patient and family experience and allow for…
- Conditions
- Laceration of Skin, Anxiety, Discharge Time
- Trial name
- NCT05934669
- Testing
- Intranasal Midazolam, Intranasal Dexmedetomidine, Intranasal Ketamine
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Acne Vulgaris
A Study Comparing Tretinoin Gel Microsphere, 0.1% and RETIN-A MICRO ® Gel Microsphere, 0.1% in the Treatment of Acne Vulgaris
To demonstrate the therapeutic equivalence and safety of Tretinoin Gel Microsphere, 0.1% (Taro Pharmaceuticals U.S.A, Inc.) and RETIN-A MICRO® (Tretinoin) Gel Microsphere, 0.1% (Valeant) in the treatment of acne vulgaris.
- Trial name
- NCT04883736
- Testing
- Tretinoin Gel Microsphere, 0.1%, RETIN-A MICRO® (Tretinoin) Gel Microsphere, 0.1%
- Where
- United States
- Volunteers
- 973 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Acne Vulgaris
A Study Comparing Tretinoin Gel Microsphere, 0.04% and RETIN-A MICRO ® Gel Microsphere, 0.04% in the Treatment of Acne Vulgaris
To demonstrate the efficacy, therapeutic equivalence and safety of tretinoin gel microsphere, 0.04% (Sun Pharmaceutical Industries, Inc.) and RETIN-A MICRO ® (tretinoin) gel microsphere, 0.04% (Reference Listed Drug) in the…
- Trial name
- NCT07469228
- Testing
- Tretinoin Gel Microsphere, 0.04%, RETIN-A MICRO® (Tretinoin) Gel Microsphere, 0.04%
- Where
- United States
- Volunteers
- 1,043 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.