Clinical trials: Positive End Expiratory Pressure
Craniotomy Surgery, Pediatric Patient Safety
The Effect Of Positive End-Expiratory Pressure on Optic Nerve Sheath Diameter In Pediatric Patients Undergoing Craniotomy in Supine Position
This study evaluated the effect of positive end-expiratory pressure (PEEP) on optic nerve sheath diameter (ONSD), an indicator of intracranial pressure, in pediatric patients undergoing craniotomy in the supine position.
- Conditions
- Craniotomy Surgery, Pediatric Patient Safety, Pediatric Patient, Positive End-expiratory Pressure (PEEP)
- Trial name
- NCT07370779
- Testing
- General Anesthesia, Anesthetic Agents, mechanical ventilation (MV)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Critically Ill Severe Bronchiolitis
Helmet Continuous Positive Airway Pressure Support for Severe Bronchiolitis in PICUs
Binary randomized peep level of Helmet CPAP (1-0). The first patient enrolled will be assign to treatment 1 (10 cmH2O peep level), independently from its BSS.
- Trial name
- NCT02977585
- Testing
- 10 cmH2O peep
- Where
- Italy
- Volunteers
- 126 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Pediatric Acute Respiratory Distress Syndrome
Pediatric Positive End Expiratory Pressure (PEEP) Titration Using Electrical Impedence Tomography (EIT)
The goal of this clinical trial is to perform a PEEP titration protocol and use EIT to identify the optimal PEEP at which lung overdistention and collapse are most effectively balanced.
- Trial name
- NCT06684119
- Testing
- Electrical Impedance Tomography positive end-expiratory pressure titration
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Hospital Los Angeles
PreTerm Neonate, Positive End Expiratory Pressure (PEEP)
PEEP FOR LUNG RECRUITMENT IN PRETERM INFANTS-EIT STUDY
Babies born early (under 32 weeks) are at risk of developing lung problems after birth. A major reason for this is that the lungs are not fully developed.
- Conditions
- PreTerm Neonate, Positive End Expiratory Pressure (PEEP), Lung Recruitment, Electrical Impedance Tomography (EIT)
- Trial name
- [PEOPLE] (NCT06705257)
- Testing
- Studying the effects of varying levels of PEEP using Electrical impedance tomography
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- South Tees Hospitals NHS Foundation Trust
General Anesthesia
Determination of Optimal Positive End-expiratory Pressure Using Electrical Impedance Tomography in Children Under General Anesthesia: Comparison Between Supine and Prone Positions
The purpose of this study was to determine the appropriate positive end-expiratory pressure (PEEP) using electrical impedance tomography (EIT) in children under general anesthesia and to investigate whether there is a difference…
- Trial name
- NCT05275309
- Testing
- Exploration of optimal PEEP in supine and prone position
- Where
- South Korea
- Volunteers
- 33 people
- Sponsor
- Seoul National University Hospital
Respiratory Compliance
Exploration of the Appropriate Combination of Positive End Expiratory Pressure and Tidal Volume Using the Intratidal Compliance Volume Profile in Children
In children under 6 years of age undergoing regular surgery during general anesthesia, the intratidal compliance profile is evaluated when different tidal volumes are applied at different positive end expiratory pressures.
- Trial name
- NCT04633720
- Testing
- Changes in positive end-expiratory pressure and tidal volume
- Where
- South Korea
- Volunteers
- 43 people
- Sponsor
- Seoul National University Hospital
Ventilation Therapy; Complications
Optimal PEEP in Pediatric Patients Under 17 Years of Age.
This study aimed to investigate the differences in positive end-expiratory pressure titration in the supine and prone positions by age in pediatric patients under 17 years of age who received general anesthesia and then evaluate…
- Trial name
- NCT05726877
- Testing
- ventilation strategy
- Where
- South Korea
- Volunteers
- 51 people
- Sponsor
- Seoul National University Hospital
Acute Respiratory Distress Syndrome
PEEP Recruitment-comparison Between Ultrasonographic Assessment and LIP Assessment
The purpose of this study is to compare lung recruitment in acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) based on lower inflection point with transthoracic ultrasonographic assessment of lung recruitment.
- Trial name
- NCT01478217
- Where
- Croatia
- Volunteers
- 17 people
- Sponsor
- Sisters of Mercy University Hospital
Pediatric Surgery
Determination of Best PEEP (Positive End-expiratory Pressure) in Anesthetized Infants in Terms of Prevention of Atelectasis
Purpose of research; to determine the appropriate positive end-expiratory pressure to minimize atelectasis during general anesthesia in infants.
- Trial name
- NCT03969173
- Testing
- applying PEEP3, applying PEEP6, applying PEEP9
- Where
- South Korea
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Acute Respiratory Distress Syndrome
PEEP Test and Gas Exchange in ALI/ARDS Patients
The investigators aim to study the effect of different levels of PEEP in ALI/ARDS patients on gas exchange.
- Trial name
- NCT00284102
- Testing
- Mechanical ventilation
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Policlinico Hospital
Positive End Expiratory Pressure
Efficacy Evaluation of Positive End-expiratory Pressure in Children Undergoing Mechanical Ventilation Using Supraglottic Airway Device
The aim of this study is to determine whether application of positive end-expiratory pressure (PEEP) improves respiratory data including respiratory compliance in children who receive positive pressure ventilation using…
- Trial name
- NCT05275283
- Testing
- PEEP
- Where
- South Korea
- Volunteers
- 94 people
- Sponsor
- Seoul National University Hospital
Infant, Newborn, Infant, Low Birth Weight
Delivery Room CPAP in Extremely Low Birth Weight Infants
This pilot study was designed to determine the feasibility of randomizing extremely low birth weight (ELBW) infants <28 weeks' gestation who required resuscitation to one of two resuscitation methods, either: (a) 100% oxygen by…
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- DR-CPAP (NCT01223274)
- Testing
- CPAP/PEEP, Standard management practices
- Where
- 6 sites in United States
- Volunteers
- 104 people
- Sponsor
- NICHD Neonatal Research Network
Transient Tachypnea of the Newborn
Positive End Expiratory Pressure With A T-piece Resuscitator For Near-Term and Term Infants With Respiratory Distress
Evaluating the effect of early application of Continuous positive airway pressure (CPAP) via Neopuff in cases of transient tachypnea of the newborn(TTN) and its role in decreasing the duration and complication of TTN.
- Trial name
- NCT01859533
- Testing
- Neopuff
- Volunteers
- 64 people
- Sponsor
- Ain Shams University
Respiratory Insufficiency Syndrome of Newborn, Infant, Premature, Diseases
PEEP and V/Q Mismatch in Premature Infants
Positive end-expiratory pressure (PEEP) is used in premature infants receiving mechanical ventilation to maintain lungs open and facilitate gas exchange.
- Trial name
- NCT03109613
- Testing
- Positive end-expiratory pressure (PEEP)
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- Children's Hospital of Philadelphia
Tricuspid Regurgitation, Mechanical Ventilation Pressure High
Effect of PEEP on TRJV in Mechanically Intubated Pediatric Patients
Prospective observational cohort study within the Pediatric Intensive Care Unit (PICU). We will perform point-of-care-ultrasound (POCUS) to quantify tricuspid regurgitant jet velocity (TRJV) on mechanically ventilated (MV)…
- Conditions
- Tricuspid Regurgitation, Mechanical Ventilation Pressure High, Pediatric Respiratory Diseases
- Trial name
- NCT06229886
- Testing
- Application of positive-end-expiratory pressure
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Positive Expiratory Pressure, Acute Respiratory Distress Syndrome
Determination of the Best Positive End-expiratory Pressure (PEEP)
Determination of the best positive end-expiratory pressure (PEEP) based on oxygenation or driving pressure in patients with acute respiratory distress syndrome (ARDS) after cardiothoracic surgery The use of a positive…
- Trial name
- DROP (NCT03969407)
- Where
- France
- Volunteers
- 118 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Apnea
Fraction of Oxygen on Induction of Anesthesia in Infants
Invesetigators evaluated the effect of positive end-expiratory pressure during anaesthesia induction on nonhypoxic apnoea time in infants.
- Trial name
- PEEP (NCT04722276)
- Testing
- positive end expiratory pressure, fraction of inspired oxygen 80%
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Seoul National University Hospital
Pediatric Anesthesia
PEEP During Induction of Anesthesia in Small Children
Positive end-expiratory pressure (PEEP) applied during induction of anesthesia prevents atelectasis formation and increases the duration of nonhypoxic apnea in obese and nonobese patients.
- Trial name
- NCT03540940
- Testing
- PEEP, ZEEP
- Where
- 2 sites in South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Mechanical Ventilation Pressure High, Bariatric Surgery Candidate
Effect of Individualized PEEP on Postoperative Pulmonary Complication in Bariatrics
Ventilation with low tidal volume and high PEEP (positive end expiratory pressure) has been shown to improve oxygenation in patients with ARDS (acute respiratory distress syndrome).
- Trial name
- NCT06168162
- Testing
- titated PEEP to best static compliance
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Oxygen Toxicity, Anesthesia; Adverse Effect
Lung Ultrasound Guided Choice of Best Positive End-Expiratory Pressure in Neonatal Anesthesia
The goal of this RCT is to demonstrate that, in neonatal anesthesia, the use of Lung Ultrasound (LUS) to guide choice of best Positive End-Expiratory Pressure (Peep) - the one that efficiently avoids lung atelectasis - leads to…
- Trial name
- NCT05737407
- Testing
- LUS-guided choice of Peep, Standard choice of Peep
- Where
- Italy
- Volunteers
- 280 people
- Sponsor
- Vittore Buzzi Children's Hospital