Clinical trials: Positive End-expiratory Pressure (PEEP)
Transient Tachypnea of the Newborn
Positive End Expiratory Pressure With A T-piece Resuscitator For Near-Term and Term Infants With Respiratory Distress
Evaluating the effect of early application of Continuous positive airway pressure (CPAP) via Neopuff in cases of transient tachypnea of the newborn(TTN) and its role in decreasing the duration and complication of TTN.
- Trial name
- NCT01859533
- Testing
- Neopuff
- Volunteers
- 64 people
- Sponsor
- Ain Shams University
Craniotomy Surgery, Pediatric Patient Safety
The Effect Of Positive End-Expiratory Pressure on Optic Nerve Sheath Diameter In Pediatric Patients Undergoing Craniotomy in Supine Position
This study evaluated the effect of positive end-expiratory pressure (PEEP) on optic nerve sheath diameter (ONSD), an indicator of intracranial pressure, in pediatric patients undergoing craniotomy in the supine position.
- Conditions
- Craniotomy Surgery, Pediatric Patient Safety, Pediatric Patient, Positive End-expiratory Pressure (PEEP)
- Trial name
- NCT07370779
- Testing
- General Anesthesia, Anesthetic Agents, mechanical ventilation (MV)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Prostate Cancer
Effects of PEEP on Intracranial and Intraocular Pressure in Robot-assisted Laparoscopic Radical Prostatectomy
To investigate the effects of positive end-expiratory pressure (PEEP) on the intracerebral pressure (ICP) and intraocular pressure (IOP) in patients undergoing robot assisted laparoscopic radical prostatectomy (RALRP)
- Trial name
- NCT03031613
- Testing
- PEEP group, ZEEP group
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Newborn Resuscitation
PEEP Resuscitation Trial
Each year, almost 3 million newborn babies die within their first month of life, often as a consequence of labour complications. Approximately 5% of newborns will not start breathing at birth and need immediate help.
- Trial name
- PEEPrest (NCT02971553)
- Testing
- Upright Resuscitator with PEEP, Upright Resuscitator
- Where
- Tanzania
- Volunteers
- 330 people
- Sponsor
- Helse Stavanger HF
Infant, Newborn, Infant, Low Birth Weight
Delivery Room CPAP in Extremely Low Birth Weight Infants
This pilot study was designed to determine the feasibility of randomizing extremely low birth weight (ELBW) infants <28 weeks' gestation who required resuscitation to one of two resuscitation methods, either: (a) 100% oxygen by…
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- DR-CPAP (NCT01223274)
- Testing
- CPAP/PEEP, Standard management practices
- Where
- 6 sites in United States
- Volunteers
- 104 people
- Sponsor
- NICHD Neonatal Research Network
General Anesthesia
Determination of Optimal Positive End-expiratory Pressure Using Electrical Impedance Tomography in Children Under General Anesthesia: Comparison Between Supine and Prone Positions
The purpose of this study was to determine the appropriate positive end-expiratory pressure (PEEP) using electrical impedance tomography (EIT) in children under general anesthesia and to investigate whether there is a difference…
- Trial name
- NCT05275309
- Testing
- Exploration of optimal PEEP in supine and prone position
- Where
- South Korea
- Volunteers
- 33 people
- Sponsor
- Seoul National University Hospital
Preoxygenation
Physiological Effects of Different Preoxygenation Strategies
The goal of this clinical trial is to evaluate the performance and physiological effects of different preoxygenation devices in healthy adult and pediatric volunteers (children aged 5-12 years).
- Trial name
- PREOXY II (NCT07564050)
- Testing
- Nasal cannula (NC), Non-rebreather mask (NRM), Non-rebreather mask (NRM) plus Nasal cannula (NC)
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Institute of Mountain Emergency Medicine
Acute Respiratory Distress Syndrome
PEEP Test and Gas Exchange in ALI/ARDS Patients
The investigators aim to study the effect of different levels of PEEP in ALI/ARDS patients on gas exchange.
- Trial name
- NCT00284102
- Testing
- Mechanical ventilation
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Policlinico Hospital
PreTerm Neonate, Positive End Expiratory Pressure (PEEP)
PEEP FOR LUNG RECRUITMENT IN PRETERM INFANTS-EIT STUDY
Babies born early (under 32 weeks) are at risk of developing lung problems after birth. A major reason for this is that the lungs are not fully developed.
- Conditions
- PreTerm Neonate, Positive End Expiratory Pressure (PEEP), Lung Recruitment, Electrical Impedance Tomography (EIT)
- Trial name
- [PEOPLE] (NCT06705257)
- Testing
- Studying the effects of varying levels of PEEP using Electrical impedance tomography
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- South Tees Hospitals NHS Foundation Trust
Ultrasound Guided Recruitment Manauvere, End Expiratory Pressure
Ultrasound Guided Recruitment Manauvere Versus Individualized Positive End Expiratory Pressure in Pediatric Patients Undergoing Laparoscopic Abdominal Surgery
The aim of this prospective randomized controlled study is to compare the effect of US-guided Recruitment Manauvere (RM) versus individualized positive end-expiratory pressure (PEEP) on oxygenation and preventing respiratory…
- Conditions
- Ultrasound Guided Recruitment Manauvere, End Expiratory Pressure, Pediatric Patients, Laparoscopic Abdominal Surgery
- Trial name
- NCT06306820
- Testing
- Fixed PEEP, Ultrasound-guided lung recruitment, Individualized PEEP
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University
Anesthesia Induced Atelectasis
Evaluation of the Effect of Lung Recruitment and Positive End- Expiratory Pressure (PEEP) on Anesthesia Induced Atelectasis Using Lung Ultrasound
Atelectasis is a side effect of general anesthesia which can be found in all types of interventions and patients of all ages.1-3 The reported incidence of anesthesia- induced atelectasis in children varies, ranging from 12 to 42%…
- Trial name
- NCT03069157
- Testing
- lung recruitment maneuver
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Acute Respiratory Distress Syndrome
PEEP Recruitment-comparison Between Ultrasonographic Assessment and LIP Assessment
The purpose of this study is to compare lung recruitment in acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) based on lower inflection point with transthoracic ultrasonographic assessment of lung recruitment.
- Trial name
- NCT01478217
- Where
- Croatia
- Volunteers
- 17 people
- Sponsor
- Sisters of Mercy University Hospital
Apnea
Fraction of Oxygen on Induction of Anesthesia in Infants
Invesetigators evaluated the effect of positive end-expiratory pressure during anaesthesia induction on nonhypoxic apnoea time in infants.
- Trial name
- PEEP (NCT04722276)
- Testing
- positive end expiratory pressure, fraction of inspired oxygen 80%
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Seoul National University Hospital
Lung Compliance
Individualized Positive End-expiratory Pressure Evaluation Using the Intratidal Compliance-volume Profile in Children
The investigators assess the changes in respiratory compliance according to different levels of positive end expiratory pressure (PEEP) in children under general anesthesia.
- Trial name
- NCT03533296
- Testing
- Positive end expiratory pressure (PEEP)
- Where
- South Korea
- Volunteers
- 47 people
- Sponsor
- Seoul National University Hospital
Pediatric Acute Respiratory Distress Syndrome
Pediatric Positive End Expiratory Pressure (PEEP) Titration Using Electrical Impedence Tomography (EIT)
The goal of this clinical trial is to perform a PEEP titration protocol and use EIT to identify the optimal PEEP at which lung overdistention and collapse are most effectively balanced.
- Trial name
- NCT06684119
- Testing
- Electrical Impedance Tomography positive end-expiratory pressure titration
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Hospital Los Angeles
Respiratory Compliance
Exploration of the Appropriate Combination of Positive End Expiratory Pressure and Tidal Volume Using the Intratidal Compliance Volume Profile in Children
In children under 6 years of age undergoing regular surgery during general anesthesia, the intratidal compliance profile is evaluated when different tidal volumes are applied at different positive end expiratory pressures.
- Trial name
- NCT04633720
- Testing
- Changes in positive end-expiratory pressure and tidal volume
- Where
- South Korea
- Volunteers
- 43 people
- Sponsor
- Seoul National University Hospital
Pediatric Anesthesia
PEEP During Induction of Anesthesia in Small Children
Positive end-expiratory pressure (PEEP) applied during induction of anesthesia prevents atelectasis formation and increases the duration of nonhypoxic apnea in obese and nonobese patients.
- Trial name
- NCT03540940
- Testing
- PEEP, ZEEP
- Where
- 2 sites in South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Mechanical Ventilation Pressure High, Bariatric Surgery Candidate
Effect of Individualized PEEP on Postoperative Pulmonary Complication in Bariatrics
Ventilation with low tidal volume and high PEEP (positive end expiratory pressure) has been shown to improve oxygenation in patients with ARDS (acute respiratory distress syndrome).
- Trial name
- NCT06168162
- Testing
- titated PEEP to best static compliance
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Ventilation Therapy; Complications, Congenital Heart Disease
Influence of Positive-End-Expiratory-Pressure (PEEP) on Cardiac Output in Mechanically Ventilated Children
Interventional Trial to determine the Effect of different PEEP levels on Cardiac output and right-ventricular function in mechanically ventilated children < 5 years of age with congenital heart disease.
- Conditions
- Ventilation Therapy; Complications, Congenital Heart Disease, Children, Only, Hemodynamic Instability
- Trial name
- IPCOM (NCT06270485)
- Testing
- PEEP
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 58 people
- Sponsor
- Charite University, Berlin, Germany
Anesthesia, Child
Effect of PEEP on Gastric Insufflation During Face Mask Induction of General Anesthesia in Children
The aim of our study is first to assess the effect of different PEEP levels on gastric volume using ultrasonography during induction of general anesthesia in children undergoing elective surgery
- Trial name
- NCT06127173
- Testing
- Positive End Expiratory Pressure PEEP
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Kasr El Aini Hospital