Clinical trials: Post Cardiac Surgery
Congenital Heart Disease (CHD)
Biventricular Pacing in Children After Surgery for Congenital Heart Disease
Surgery with cardiopulmonary bypass (CPB) for congenital heart disease (CHD) causes low cardiac index (CI). With the increasing success of surgery for CHD, mortality has decreased and emphasis has shifted to post-operative…
- Trial name
- NCT02806245
- Testing
- Biventricular pacing
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- The Hospital for Sick Children
Cardiac Toxicity, Sarcoma
Combination Chemotherapy Before and After Surgery in Treating Patients With Osteosarcoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving chemotherapy before surgery may shrink the tumor so that it can be removed during surgery.
- Trial name
- NCT00019864
- Testing
- filgrastim, cisplatin, dexrazoxane hydrochloride
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- National Cancer Institute (NCI)
Congenital Heart Disease in Children
How to Report Postoperative Outcomes After a Paediatric Cardiac Surgery ?
Congenital heart disease is a common abnormality in newborns. The marked improvement in the surgical management of congenital heart disease has led to a reduction in postoperative mortality, historically a quality criterion for…
- Trial name
- Pedia-Card (NCT05546983)
- Where
- France
- Volunteers
- 189 people
- Sponsor
- University Hospital, Strasbourg, France
Congenital Heart Disease (CHD), Postoperative Sleep
Starry-Sky Projection and Maternal Voice for Sleep After Pediatric Cardiac Surgery
The goal of this clinical trial is to determine whether a starry-sky projection affects sleep during the early period after cardiac surgery in young children.
- Trial name
- NCT07854145
- Testing
- Starry-Sky Projection, Conventional Lighting, Maternal Voice
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Opioid Use, Post-thoracotomy Pain Syndrome
Serratus Anterior Plane Block for Management of Post Thoracotomy Pain
This is a single-center, randomized, prospective study evaluating the effect of serratus anterior plane block performed after induction of anesthesia, but before the start of surgery on postoperative opioid requirements.
- Conditions
- Opioid Use, Post-thoracotomy Pain Syndrome, Local Anaesthetic Agent Overdose, Local Anesthetic Complication
- Trial name
- SAPB (NCT04258436)
- Testing
- Serratus anterior block
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Indiana University
Respiratory Distress Syndrome, Adult, Thoracic Surgery
Risk Factors and Prediction Score of ARDS After Cardiac Surgery
Acute respiratory distress syndrome following cardiac surgery severely affects the prognosis of patients; the mortality is up to 40%.
- Conditions
- Respiratory Distress Syndrome, Adult, Thoracic Surgery, Risk Factors
- Trial name
- NCT02759770
- Testing
- no intervention
- Where
- China
- Volunteers
- 1,333 people
- Sponsor
- Beijing Anzhen Hospital
Heart Surgery Via Sternotomy, Post-operative Analgesia
Advantage of Tramadol in Local Analgesia Post-Sternotomy
Sternotomy, the reference approach for heart surgery, may induce profound and intense post-operative pain. One method of analgesia used is patient-controlled intravenous morphine.
- Trial name
- ATLAS (NCT02851394)
- Testing
- Levobupivacaine, tramadol
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Inflammation, Cardiac Surgical Procedures
Inflammatory Responses to Lipid Emulsions in Children Before and After Open Heart Surgery
This study is a blinded, randomized, controlled prospective trial comparing immune response (sepsis, inflammatory response, pulmonary vasoconstriction) in 2 groups of infants less than 3-month old receiving pre and post…
- Trial name
- NCT00336908
- Testing
- a combination of MCT, LCT , and Fish Oil
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of Alberta
Coronary Artery Bypass Surgery
Pre- and Postoperative Cardiopulmonary Rehabilitation Reduces Complications After Coronary Artery Bypass Surgery: A Randomized Trial
Pre- and postoperative cardiopulmonary rehabilitation reduces complications after coronary artery bypass surgery. This study was conducted as a randomized trial to verify this hypothesis in our institution. ICSC
- Trial name
- NCT00670176
- Testing
- REHAB (Pre- and postoperative cardiopulmonary rehabilitation)
- Volunteers
- 56 people
- Sponsor
- Universidade do Sul de Santa Catarina
Hemostasis
In Vivo Effects of Fibrinogen Concentrate (FC) Versus Cryoprecipitate on the Neonatal Fibrin Network Structure After Cardiopulmonary Bypass (CPB)
This primary aim of this study is to compare the in vivo effects of fibrinogen concentrate and cryoprecipitate on the neonatal fibrin network after surgery with cardiopulmonary bypass to develop effective and safe strategies for…
- Trial name
- NCT03932240
- Testing
- Fibrinogen Concentrate (FC), Cryoprecipitate
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Emory University
Acute Kidney Injury
Preoperative Prediction of Acute Kidney Injury After Cardiac Surgery
Although acute kidney injury (AKI) frequently complicates cardiac surgery, methods to determine AKI risk are lacking. Renal functional reserve (RFR), the capacity of the intact nephron mass to increase glomerular filtration rate…
- Trial name
- RFR (NCT03092947)
- Testing
- No intervention
- Volunteers
- 110 people
- Sponsor
- University of Giessen
Heart Defects, Congenital
The Use of Music for Neonates Post-Cardiac Surgery
The purpose of this study is to explore the feasibility of implementing nurse-led music therapy in a cohort of neonates admitted to the Cardiac Intensive Care Unit (CICU) post congenital heart surgery.
- Trial name
- NCT03925584
- Testing
- Music Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Boston Children's Hospital
Infant ALL, Congenital Heart Disease
Determining the Effect of Two Different Methods in Children to Maintain Drain Patency After Cardiac Surgery
In this study, it was aimed to determine the effect of the use of milking and sucking methods on bleeding amount, vital signs and oxygen saturation in children with chest and mediastinal drains after cardiac surgery.
- Trial name
- NCT04454294
- Testing
- Control, Experimental Group (Absorption Group), Experimental Group (Milking Group)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Acibadem University
Neonatal Disease, Post-Surgical Complication
Cardiac Surgery Recovery in Infants Assessed Using Neoneur Feeding System
A prospective non-randomized longitudinal design of 30-40 infants from initiation of oral feeding until discharge to track feeding changes as a potential indicator of surgical recovery.
- Conditions
- Neonatal Disease, Post-Surgical Complication, Cardiac Disease
- Trial name
- NCT06569641
- Testing
- Neoneur Feeding System
- Volunteers
- 35 people
- Sponsor
- Neoneur LLC
Complex Congenital Heart Disease
Noninvasive Measurement of the Cerebral Autoregulation in Neonates and Infants With Complex Congenital Heart Disease
Feasibility of non-invasive cerebral autoregulation measurement at the PICU and impact of changes in oxygen supply
- Trial name
- NCT04810013
- Testing
- non-invasive measurement of cerebral autoregulation
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University Hospital Tuebingen
Pediatric Patients, Congenital Heart Surgery
Pain Management of Pecto-intercostal Fascial Block Versus Intravenous Fentanyl After Pediatric Cardiac Surgery
Cardiac surgical patients often experience significant postoperative pain at the median sternotomy site. In pediatric cardiac surgery, the recommended pre bypass dose of fentanyl to blunt the hemodynamic and metabolic stress…
- Trial name
- NCT04945694
- Testing
- Ultrasound-guided bilateral pecto-intercostal fascial block, Intravenous fentanyl, Propofol
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Cardiac; Dysrhythmia, Postoperative, Congenital Heart Surgery
Prevention of Post-Operative Cardiac Arrhythmias
Aim 1: Primary Prevention of Post-operative Cardiac Arrhythmias 1. To evaluate the efficacy of dexmedetomidine vs. the combination of Magnesium Sulfate and dexmedetomidine for the prevention of post-operative cardiac arrhythmias…
- Trial name
- POCA (NCT04234906)
- Testing
- Dexmedetomidine, Magnesium Sulfate, Amiodarone
- Volunteers
- 870 people, healthy volunteers welcome
- Sponsor
- Jeffrey Moak
Aortic Valve Disease
Long-Term Follow-up After the Autograft Aortic Valve Procedure (Ross Operation)
With the current knowledge of aortic valve replacement modalities, no specific recommendations can be given and the decision for a particular prosthesis or procedure is rather arbitrarily.
- Trial name
- NCT00708409
- Testing
- Cardiac valve surgery
- Where
- Germany
- Volunteers
- 1,800 people
- Sponsor
- University of Luebeck
Congenital Heart Defects
Model-based Versus Traditional Warfarin Dosing in Children
This study compares the clinical effectiveness of a new algorithm (model-based warfarin dosing) with standard practice (doctor's own judgement and intuition) designed to determine the most appropriate anticoagulant dose of…
- Trial name
- WATCH (NCT02475863)
- Testing
- Warfarin Dosing Aid, Standard Practice
- Volunteers
- 45 people
- Sponsor
- De Montfort University
Coronary Disease
Obtain Additional Information on Use of CorMatrix ECM (Extracellular Matrix)
The objective of the study is to actively gather additional information on the use of CorMatrix ECM for pericardial reconstruction.
- Trial name
- RECON (NCT02073331)
- Where
- 43 sites in United States
- Volunteers
- 1,420 people
- Sponsor
- Elutia Inc.