Clinical trials: Post Cardiac Surgery
Postoperative Chylothorax, Congenital Heart Disease
Propranolol Treatment for Postoperative Chylothorax
Postoperative chylothorax is a serious complication after open heart surgery for pediatric patients with congenital heart disease (CHD).
- Conditions
- Postoperative Chylothorax, Congenital Heart Disease, Open Heart Surgery, Chylothorax
- Trial name
- NCT06833320
- Testing
- Propranolol Hydrochloride
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- June Wu
Respiratory, Postoperative Pain
The Effect of Pranayama on Pain and Respiration After Coronary Bypass Surgery
After CABG surgery, patients tend to breathe superficially because they experience pain while breathing. By restricting deep inspiration and cough; There is a decrease in lung tidal volume, vital capacity, and functional residual…
- Conditions
- Respiratory, Postoperative Pain, Nursing
- Trial name
- NCT06485531
- Testing
- Pranamaya, Pursed Lips Breathing
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Oliceridine, Postoperative Cardiac Surgery
1.Comparison of the Analgesic Effect of Remifentanil Group and Different Dose Groups of Oliceridine in Postoperative Patients Undergoing Cardiac Surgery 2.Exploring the Hemodynamic Effects of Analgesic Regimens With Different Doses of Oliceridine After Cardiac Surgery
Cardiac surgery has the characteristics of long duration and large amount of intraoperative bleeding, easy to involve multiple organs and severe tissue injury, which is one of the most serious surgical procedures with…
- Trial name
- NCT06619145
- Testing
- Low dose Oliceridine, High dose Oliceridine
- Where
- 2 sites in China
- Volunteers
- 270 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Coronary Artery Bypass
Neurocognitive Outcome After Coronary Artery Bypass Surgery Using Minimal Versus Conventional Extracorporeal Circulation
The aim of this study is to assess the effect of minimal (MECC) versus conventional (CECC) extracorporeal circulation on neurocognitive function after elective coronary bypass grafting (CABG) as well as whether this can be…
- Trial name
- NCT01213511
- Testing
- Coronary artery bypass grafting with the use of minimal extracorporeal circulation, Coronary artery bypass grafting under conventional extracorporeal circulation
- Where
- Greece
- Volunteers
- 64 people
- Sponsor
- AHEPA University Hospital
Complex Congenital Heart Disease, Enhanced Recovery After Surgery
The Application of Enhanced Recovery After Surgery (ERAS) for Cardiovascular Surgery in the Correction of Complex Congenital Heart Disease
This study is a multicenter, stepwise design, cluster randomized controlled trial. Random sequence is generated by computer, and each center enters the intervention expectation (Phase I) in random order to implement ERAS…
- Trial name
- NCT05914103
- Testing
- ERAS
- Where
- 2 sites in China
- Volunteers
- 3,030 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Malnutrition
Pilot Study of the Safety and Efficacy of Oxandrolone in the Prevention and Treatment of Malnutrition in Infants
Oxandrolone is an anabolic steroid, marketed in the United States as an adjunctive therapy to combat weight loss resulting from chronic infection, extensive surgery, severe trauma, protein catabolism associated with prolonged…
- Trial name
- NCT01048632
- Testing
- Oxandrolone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Utah
Deglutition Disorders in Children, Congenital Heart Disease
Speech Therapy Online Approach for Children With Congenital Heart Desease in Pre and Post Surgical Period
The goal of this clinical trial is to test the results of a protocoled speech therapy online intervention in children with congenital heart disease aged between 0 and 12 months old, who feeds tube only.
- Trial name
- NCT07481565
- Testing
- Oral motor intervention
- Where
- 2 sites in Brazil
- Volunteers
- 20 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Congenital Heart Disease
Improving Motor Skill Development in Infants After Cardiac Surgery
The purpose of this study is to learn more about developmental behaviors and to examine changes in developmental progress related to motor activities among a group of infants who received open heart surgery within the first three…
- Trial name
- DAISY (NCT02700646)
- Testing
- Developmental recommendations, Standard care
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Michigan
Prone posıtıon
Extruded the effectıveness of Prone posıtıon ın ınfants evaluatıon
The aim of this study was to determine the effect of prone position on vital signs, arterial blood gases and blood values in 0-1 year old infants extubated after congenital heart surgery.
- Trial name
- NCT06493058
- Testing
- Prone positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Acute Kidney Injury
An Observational Case Control Study to Identify the Role of MV and MV Derived Micro-RNA in Post CArdiac Surgery AKI
Acute kidney injury (AKI) complicates over 25% of cardiac surgical procedures where it increases mortality up to fourfold. The incidence of AKI is increasing, the pathogenesis is poorly understood, current diagnostic tests lack…
- Trial name
- MaRACAS (NCT02315183)
- Testing
- This is an observational Study
- Where
- United Kingdom
- Volunteers
- 96 people
- Sponsor
- University of Leicester
Acute Kidney Injury, Congenital Heart Disease
Acute Kidney Injury After Cardiac Surgery on CPB
The purpose of this retrospective study is to determine the incidence and severity of acute kidney injuries (AKI) after heart surgery on cardiopulmonary bypass (CPB) in the pediatric intensive care unit (PICU) in Lausanne…
- Conditions
- Acute Kidney Injury, Congenital Heart Disease, Surgery, CBP
- Trial name
- NCT03513718
- Where
- Switzerland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Children, Cardiac Surgery
Diagnosis Of Pulmonary Complications After Cardiac Surgery In Children
Pulmonary complications are frequent in cardiac surgery, representing an important cause of morbidity, prolongation of hospital stay and need for repeated examinations.Chest X-rays are done routinely and even multiple times to…
- Conditions
- Children, Cardiac Surgery, Ultrasound
- Trial name
- NCT03563196
- Testing
- Chest Radiograph, Lung Ultrasound
- Where
- Nepal
- Volunteers
- 141 people
- Sponsor
- Shahid Gangalal National Heart Centre
Pediatric Patients, Congenital Heart Surgery
Pain Management of Pecto-intercostal Fascial Block Versus Intravenous Fentanyl After Pediatric Cardiac Surgery
Cardiac surgical patients often experience significant postoperative pain at the median sternotomy site. In pediatric cardiac surgery, the recommended pre bypass dose of fentanyl to blunt the hemodynamic and metabolic stress…
- Trial name
- NCT04945694
- Testing
- Ultrasound-guided bilateral pecto-intercostal fascial block, Intravenous fentanyl, Propofol
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Heart Valve Replacement
The German Plug - Registry
In approximately 10-15% of all patients after surgical or interventional heart valve replacement, flapping defects appear as complications in the long-term course, so-called paravalvular / paraprothetic leaks (PVL).
- Trial name
- PLUG (NCT03179969)
- Testing
- paravalvular leak
- Where
- Germany
- Volunteers
- 49 people
- Sponsor
- Stiftung Institut fuer Herzinfarktforschung
Low Cardiac Output Syndrome Bypass Children
Performance of Carbon Dioxide (CO2)-Derived Parameters in Predicting Low Cardiac Output Syndrome
In congenital cardiac intensive care, low cardiac output syndrome (LCOS) after surgery is defined by a decrease in cardiac output due to cardiac dysfunction.
- Trial name
- GAP-CO2 (NCT07770386)
- Where
- France
- Volunteers
- 306 people
- Sponsor
- University Hospital, Lille
Atrial Fibrillation
Atrial Fibrillation After Cardiac Surgery-comparing Conventional and Miniaturized Bypass Systems
Atrial fibrillation (AF) is the most common arrhythmia after cardiac surgery. The incidence of AF varies between 20 - 45 % after (coronary artery bypass grafting) CABG.
- Trial name
- NCT01160393
- Testing
- Miniaturized bypass system
- Where
- Finland
- Volunteers
- 240 people
- Sponsor
- Kuopio University Hospital
Heart Defects, Congenital, Surgery
Feasibility Study Over the NAVA Mode in Noninvasive Ventilation After Cardiac Surgery in Infants.
Neonates who underwent cardiac surgery with cardiopulmonary bypass almost always require non-invasive respiratory support (NIV) in relay to conventional ventilation.
- Trial name
- NIVNAVA (NCT01570933)
- Testing
- NivNava, Cpap
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Cardiac Defect, Cardiac Anomaly
Post Market Observational Retrospective Study of Glycar Bovine Pericardial Patch (CIP-003)
The overall purpose of this observational Post Market Clinical Follow Up (PMCF) study is to ensure continued acceptability of the benefit risk ratio by assessment of safety and performance, in patients undergoing cardiovascular…
- Conditions
- Cardiac Defect, Cardiac Anomaly, Pericardial Defect
- Trial name
- NCT06088680
- Testing
- Glycar Pericardial Patch
- Where
- South Africa
- Volunteers
- 50 people
- Sponsor
- GLYCAR SA (Pty) Ltd
Ventricular Septal Defect
Immune Heterogeneity Before and After Cardiopulmonary Bypass in Children
The goal of this observational study is to learn about functional heterogeneity of immune cells before and after cardiopulmonary bypass (CPB) in children with congenital heart disease (CHD).
- Trial name
- NCT06214182
- Where
- China
- Volunteers
- 3 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Laryngeal Injury, Swallowing Disorder
Laryngeal Disorders After Childhood Cardiac Surgery
Laryngeal disorders after childhood cardiac surgery is a complication well described in the literature. However, the long term progression of the affected children has never been studied (all the studies stopped before 2 years of…
- Conditions
- Laryngeal Injury, Swallowing Disorder, Voice Disorders in Children, Surgery--Complications
- Trial name
- RECUP-TML (NCT04638361)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Hospices Civils de Lyon