Clinical trials: Post Discharge
Maternal Sepsis, Neonatal Sepsis
Smart Discharges for Mom & Baby
This study aims to build a predictive algorithm that identifies mother-newborn dyads most at risk of death or complications in the 6 weeks after birth.
- Trial name
- NCT05730387
- Testing
- Observational only
- Where
- Canada
- Volunteers
- 7,182 people
- Sponsor
- University of British Columbia
Pancreatic Fistula
Closed Suction Drainage and Natural Drainage of the Pancreatic Duct in Pancreaticojejunostomy
Pancreaticojejunal anastomosis leakage is a major complication after pancreatoduodenectomy and various technical methods have been examined to improve the situation.However, none of methods have been successful at improving…
- Trial name
- NCT00679952
- Testing
- closed suction drainage of pancreatic duct, natural drainage of pancreatic duct
- Where
- South Korea
- Volunteers
- 168 people
- Sponsor
- Seoul National University Hospital
Postoperative Bile Leak, Focal Liver Lesions
Prevention of Bile Leakage After Liver Resection in Children
Bile leakage is a clinically important complication after liver resection in children and may require prolonged drainage, additional radiological or endoscopic procedures, or repeat surgery.
- Trial name
- NCT07867522
- Testing
- prophylactic extrahepatic biliary drainage during liver resection
- Where
- Russia
- Volunteers
- 12 people
- Sponsor
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Post COVID-19
Special Chinese Medicine Out-patient Programme for Discharged COVID-19 Patients
According to the ongoing observational studies and the Chinese Medicine practice guideline for COVID-19 patients, the discharged patients with COVID-19 still exhibits certain clinical symptoms such as fatigue, poor appetite…
- Trial name
- NCT04544605
- Testing
- Individualized-Chinese herbal medicine
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Hong Kong Baptist University
Abscess
Management of Skin and Soft Tissue Abscesses in Pediatric Patients After Incision and Drainage
The purpose of the study is to compare rates of cure of abscesses with and without antibiotic treatment after incision and drainage.
- Trial name
- NCT00691600
- Testing
- oral trimethoprim/sulfamethoxazole
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Baylor College of Medicine
Arthrosis
Changes in Physical Activity, Sleep and Knee Function After Same-Day Discharge Knee Arthroplasty
The goal of this observational study is to examine changes in physical activity, sleep quality, knee extension and flexion strength, knee range of motion, and patient-reported outcomes before and after same-day discharge knee…
- Trial name
- ORTOMOVE (NCT07840391)
- Testing
- Medial unicompartmental knee arthroplasty (UKA), Total knee arthroplasty (TKA)
- Where
- 2 sites in Finland
- Volunteers
- 120 people
- Sponsor
- Turku University Hospital
Emergency Delirium, Postoperative Delirium (POD)
Comparison of IV Dexmedetomidine Versus Clonidine Versus no Alpha 2 Agonist on Emergency Delirium, PACU Length of Stay and Time to Hospital Discharge in Children Undergoing (Adeno)Tonsillectomy: a Prospective Observational Study
Emergence delirium (ED) is a frequent complication in children undergoing general anesthesia, particularly following ENT procedures such as adenotonsillectomy.
- Conditions
- Emergency Delirium, Postoperative Delirium (POD), Adenotonsillectomy, Tonsillectomy
- Trial name
- CLONIDEX (NCT07913308)
- Testing
- Intravenous dexmedetomidine, Intravenous clonidine, Standard Anesthetic Care Without Alpha-2 Agonist
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Universitair Ziekenhuis Brussel
Post-traumatic Stress Disorder (PTSD), Current Significant Sleep Disturbances
Sleep Disturbances in Children and Adolescents With Post-traumatic Stress Disorder (PTSD): a Randomized Double-blind Placebo-controlled Trial to Investigate the Efficacy of Pediatric Prolonged-release Melatonin
Among the most sensitive and persistent symptoms of post-traumatic stress disorder (PTSD) in children are sleep disturbances in the insomnia spectrum (sleep onset disturbances, fragmented sleep with multiple nocturnal awakening…
- Trial name
- MelatoSomKids (NCT07418554)
- Testing
- pediatric, prolonged released melatonin
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Strasbourg, France
Patients Above 18 Years, Patient Discharge
One Year Pacing Dependency After TAVR
Pace maker implantation after the procedure of TAVR can be estimated at 15% of patients. However, some studies have shown that the conduction disturbances after TAVR could resolve over time, and that roughly between one- and…
- Conditions
- Patients Above 18 Years, Patient Discharge, Pacing Therapy, Aortic Stenosis (Treated With TAVI)
- Trial name
- PACETAVI (NCT06756282)
- Testing
- Pacemaker and defibrillator
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Montpellier
Fracture
Adequacy of Pain Management for Upper Extremity Fracture After Discharge From a Pediatric Emergency Depart
Pain is a common cause for children seeking care in the Emergency Department (ED). Children with orthopedic injuries often require pain control when seeking emergency care.
- Trial name
- NCT01514097
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Pancreaticoduodenectomy, Distal Pancreatectomy
Randomized Trial of Early Versus Standard Drainage Removal After Pancreatic Resections
Despite a substantial decrease in postoperative mortality, morbidity after pancreatic resections is still high, even at high-volume centers.
- Conditions
- Pancreaticoduodenectomy, Distal Pancreatectomy, Pancreatic Fistula, Abdominal Abscess
- Trial name
- NCT00931554
- Testing
- Postoperative drain removal
- Where
- Italy
- Volunteers
- 114 people
- Sponsor
- Universita di Verona
Mental Disorder in Childhood
DigiPuR: Digitally Supported Psychotherapy and Reintegration
The study "DigiPuR" (Digitally Supported Psychotherapy and Reintegration) examines the effectiveness of a new, digital aftercare program for children and adolescents after a psychiatric hospitalization in the intervention group…
- Trial name
- DigiPuR (NCT04986228)
- Testing
- Digital aftercare, TAU
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Tuebingen
Orthopaedic Surgery
The Effect of Digital Team-based Communication on Patient-initiated Telephone Contacts to Hospital After Discharge
The aim of this study is to investigate the effects of eDialogue versus standard communication pathways on patient-initiated telephone contacts to the hospital following discharge.
- Trial name
- NCT05601765
- Testing
- Standard communication pathways after discharge, Digital team-based communication after discharge
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Aalborg University Hospital
Malaria, Severe Anemia
Post-discharge Malaria Chemoprevention(PMC) Study
This study evaluates the efficacy and safety of 3 months of malaria chemoprevention post-discharge using dihydroartemisinin piperaquine (DHA-P) in children under 5 years of age admitted with severe anemia.
- Trial name
- PMC (NCT02671175)
- Testing
- dihydroartemisinin-piperaquine
- Where
- 9 sites in Kenya, Uganda
- Volunteers
- 1,049 people
- Sponsor
- Liverpool School of Tropical Medicine
Morbidity;Perinatal, Pregnancy Complications
Postpartum Outcomes in BC
For every case of maternal death, many more women experience life-threatening complications during pregnancy and childbirth. Yet, severe maternal morbidity (SMM) cases are often overlooked post-delivery.
- Conditions
- Morbidity;Perinatal, Pregnancy Complications, Pregnancy Related
- Trial name
- NCT05461183
- Testing
- Retrospective database analysis
- Volunteers
- 15,000 people
- Sponsor
- University of British Columbia
Sepsis
Smart Discharges to Improve Post-discharge Health Outcomes in Children
In Uganda, about 5% of children discharged after hospitalization for a serious infection will die in the weeks after returning home.
- Trial name
- NCT05730452
- Testing
- Risk-stratified discharge and post-discharge care
- Where
- Canada
- Volunteers
- 11,700 people
- Sponsor
- University of British Columbia
Severe Malaria, Severe Anemia
PDMC Implementation Trial in Kenya
The goal of this implementation trial is to evaluate at least two alternative delivery strategies and adherence support for malaria chemoprevention with dihydroartemisinin-piperaquine in the post-discharge management of children…
- Trial name
- PDMC-SL (NCT06624631)
- Testing
- SMS reminders; adherence support strategy a, Community Health Promoters (CHP) home visits; adherence support strategy b, No reminders; adherence support strategy c
- Where
- Kenya
- Volunteers
- 600 people
- Sponsor
- Liverpool School of Tropical Medicine
Low; Birthweight, Breast Feeding, Exclusive
Indonesia After Discharge LBW Infant HMF Supplementation Study
Low birth weight (LBW) infant (1800-2449 gram) will be given the new human milk fortifier (HMF) which contains protein, lipid, carbohydrate and micronutrients after discharge.
- Conditions
- Low; Birthweight, Breast Feeding, Exclusive, Gestational Age and Weight Conditions
- Trial name
- DAHLIA (NCT04954807)
- Testing
- human milk fortified
- Where
- 4 sites in Indonesia
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Central Nervous System Tumor, Pediatric, Fatigue
Methylphenidate HCl or Modafinil in Treating Young Patients With Excessive Daytime Sleepiness After Cancer Therapy
RATIONALE: Methylphenidate hydrochloride or modafinil may help reduce daytime sleepiness and improve the quality of life of patients with excessive daytime sleepiness after cancer therapy.
- Conditions
- Central Nervous System Tumor, Pediatric, Fatigue, Specific Disorders of Sleep
- Trial name
- NCT01348607
- Testing
- methylphenidate hydrochloride, modafinil
- Volunteers
- 1 people
- Sponsor
- University of South Florida
Pediatric Kidney Disease
Pharmacokinetics, Effectiveness and Tolerability of Prolonged-release Tacrolimus After Paediatric Kidney Transplantation
Recently, a new prolonged-release tablet version of tacrolimus (Envarsus®) using the so-called MeltDose™ (US Patent No. 7,217,431) drug-delivery technology has been approved as immunosuppressive medication for patients after…
- Trial name
- Pro-Tac (NCT06057545)
- Testing
- Envarsus®, Prograf
- Where
- 4 sites in Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital, Essen