Clinical trials: Post Operative Analgesia
Surgical Procedure, Unspecified
TFPB vs QLB III in Infra-umbilical Pediatric Surgeries
Regional anesthetic techniques; they reduce postoperative morbidity, provide early mobilization and provide great advantages by significantly reducing the need for narcotic analgesics.
- Trial name
- NCT05671484
- Testing
- Transversalis Fascial Plane Block, Quadratus Lumborum Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Namik Kemal University
Cognitive Function
Effect of Acetaminophen Preemptive Analgesia on Postoperative Cognitive Function
Patients undergoing gastrointestinal tumor surgery are prone to delayed recovery and postoperative cognitive dysfunction due to greater trauma and longer operation time.
- Trial name
- NCT06004687
- Testing
- acetaminophen mannitol, Normal saline
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Affiliated Hospital of Nantong University
Analgesia
Laparoscopic Guided Transversus Abdominis Plane Block for Postoperative Analgesia After Pediatric Laparoscopic Surgery.
The aim of this study will be to investigate the safety and analgesic efficacy of Transversus Abdominis Plane (TAB) Block versus psoas block blockade.
- Trial name
- TAB (NCT03388671)
- Testing
- TAB Block, Psoas Block, Bupivacaine
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Assiut University
Knee Arthropathy, Postoperative Pain
IPACK Block After Total Knee Arthroplasty
Adductor canal block (ACB) is a peripheral nerve blockade technique that provides good pain control in patients undergoing total knee arthroplasty (TKA) which however does not relieve posterior knee pain.
- Trial name
- NCT04295421
- Testing
- adductor canal block, IPACK block
- Where
- Tunisia
- Volunteers
- 88 people
- Sponsor
- University Tunis El Manar
Postoperative Pain Management
Escalating Ketamine Doses and Pre-emption
Ketamine affects postoperative pain when administered intravenously immediately before, during or at the end of surgical procedures.
- Trial name
- NCT01070108
- Testing
- Ketamine
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Medial Patellofemoral Ligament (MPFL) Reconstruction, Sports Injuries in Children
Evaluation of Pain Management After Surgery When Using Exparel in the Pediatric Population
The goal of this randomized clinical trial is to determine if administration of Exparel via local infiltration for medial patellofemoral ligament (MPFL) reconstruction procedures in pediatric orthopaedic sports medicine patients…
- Conditions
- Medial Patellofemoral Ligament (MPFL) Reconstruction, Sports Injuries in Children, Analgesia, Pain, Postoperative
- Trial name
- NCT06559215
- Testing
- Exparel
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Texas Scottish Rite Hospital for Children
Pain, Postoperative
Pain Control in Pediatric Posterior Spine Fusion Patients: The Effect of Gabapentin
The purpose of this study is to evaluate the patient experience when using gabapentin with other pain control medications after posterior spinal fusion surgery for scoliosis in adolescents.
- Trial name
- NCT01977937
- Testing
- Gabapentin 250mg/5mL NDC:59762-5025-01, Simple Syrup
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Oregon Health and Science University
Pain
Ultrasound-guided Rectus Sheath Block for Post-operative Pain Control Following Umbilical Hernia Repair
The purpose of this study is to compare the effectiveness of local infiltration to an ultrasound guided nerve block placed by the anesthesiologist for children undergoing umbilical hernia repair.
- Trial name
- NCT00836134
- Testing
- rectus sheath block, local anesthetic infiltration
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Seattle Children's Hospital
Opioid Analgesia
Pharmacokinetics and Safety of ORF Tablets in Pediatric Patients
The purpose of this study is to characterize the pharmacokinetics (PK) of single-dose ORF tablets in pediatric patients aged 6 to 16 years, inclusive.
- Trial name
- NCT01160614
- Testing
- Oxycodone hydrochloride controlled-release (ORF) tablets
- Where
- 17 sites in United States, Australia and 2 more
- Volunteers
- 30 people
- Sponsor
- Purdue Pharma LP
Postoperative Pain
Paravertebral Block for Postoperative Analgesia in Children Undergoing Lateral Incision Cardiac Surgery With CBP
This study aims to compare the effect of paravertebral block and local infiltration anesthesia on postoperative analgesia in children undergoing lateral incision cardiac surgery with cardiopulmonary bypass.
- Trial name
- NCT06312904
- Testing
- paravertebral block, Local infiltration anesthesia
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Scoliosis; Adolescence, Pain After Surgery
Tegileridine for Postoperative Pain After Adolescent Scoliosis Surgery
The goal of this clinical trial is to see if a new pain medicine called Tegileridine is at least as effective as morphine (the standard treatment) for pain relief after spinal surgery in teenagers with scoliosis.
- Conditions
- Scoliosis; Adolescence, Pain After Surgery, Analgesia, Patient-controlled
- Trial name
- NCT07229495
- Testing
- Tegileridine, morphine
- Where
- 6 sites in China
- Volunteers
- 171 people
- Sponsor
- Peking Union Medical College Hospital
Emergence Delirium, Extubation Time
Dexmedetomidine Reduces Emergence Delirium in Children Undergoing Tonsillectomy With Propofol Anesthesia
Dexmedetomidine (DEX) is safe and effective in reducing ED following sevoflurane anesthesia. The investigators intend to study the efficacy of DEX in reducing ED in children undergoing tonsillectomy with and without adenoidectomy…
- Conditions
- Emergence Delirium, Extubation Time, Heart Rate, Postoperative Analgesia
- Trial name
- NCT03131375
- Testing
- Dexmedetomidine, Normal saline, Bispectral index
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Athens General Children's Hospital "Pan. & Aglaia Kyriakou"
Postoperative Pain, Cerebral Palsy
Postoperative Pain in Children With Cerebral Palsy After Pelvic and Femoral Osteotomies
This study is a comparison of postoperative pain in children with cerebral palsy after surgery on the hip or femur. One group is treated with p.o.
- Trial name
- NCT00964639
- Testing
- Ropivacaine, Saline
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University of Aarhus
Congenital Hip Dysplasia
Erector Spinae Plane Block for Congenital Hip Dislocation Surgery
Developmental dysplasia of the hip (DDH) is one of the major disorder of the pediatric population with an incidence of 3 to 5 per 1000 children.
- Trial name
- NCT03949686
- Testing
- Saline Solution, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Postoperative Analgesia, Morphine and Dexmedetomidine
Compare Morphine and Dexmedetomidine as Adjuvants to Bupivacaine in Ultrasound-guided ACB for Postoperative Analgesia After Knee Surgeries
This study aims to compare morphine and dexmedetomidine as adjuvants to bupivacaine in ultrasound-guided ACB for postoperative analgesia after knee surgeries
- Trial name
- NCT07240402
- Testing
- Adductor Canal Block (ACB) Only
- Volunteers
- 15 people
- Sponsor
- Kafrelsheikh University
Bilateral Inguinal Hernia Repair, Open Upper Abdominal Surgeries
Ultrasound-guided Quadratus Lumborum Block Versus Erector Spinae Plane Block for Postoperative Analgesia in Children Undergoing Elective Open Lower Abdominal Surgeries
To compare the postoperative analgesic efficacy of ultrasound-guided Quadratus Lumborum Block (anterior approach) versus Erector Spinae Plane Block (T10-T12 level), both performed bilaterally with 0.25% bupivacaine (0.5 mL/kg per…
- Trial name
- NCT07853586
- Testing
- ultrasound guided anterior oudratus lumborum block, Ultrasound guided erector spinae plane block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University
Regional Anesthesia, Postoperative Pain, Acute
Caudal Block and Transversus Abdominis Plane Block in Pediatric Inguinal Hernia Repair
Pediatric inguinal hernia repair (IHR) candidates experiences ordinarily mild to moderate pain, rarely severe pain in the postoperative period.
- Trial name
- NCT05286190
- Testing
- Bupivacaine 0.25% Injectable Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Analgesia
Post Tonsillectomy Analgesia Comparison After Surgery Site Spray of Local Anesthesics
Check analgesia after tonsillectomy in adults
- Trial name
- NCT04325113
- Testing
- levobupivacaine
- Where
- Belgium
- Volunteers
- 44 people
- Sponsor
- University of Liege
Acute Post-operative Pain Following Caesarean Section
Opioid-free Analgesia for the Management of Acute Post-operative Pain Following Caesarean Section
Background: Multimodal analgesia; a combination of opioid and non-opioid analgesics, for management of acute post-operative pain significantly reduces the incidence of adverse effects associated with liberal post-operative opioid…
- Trial name
- OFAAPPCS (NCT04539249)
- Testing
- Magnesium sulphate, Pentazocine
- Where
- Nigeria
- Volunteers
- 324 people
- Sponsor
- Olakunle Ifeoluwa Makinde
Postoperative Nausea and Vomiting
Antiemetic Effect of the Addition of Ondansetron to the Morphine Solution in Patient-Controlled Analgesia (PCA)
PCA morphine always introduces nausea and vomiting during the postoperative period. Ondansetron can reduce PONV (postoperative nausea vomiting).
- Trial name
- NCT00199329
- Testing
- ondansetron adding in PCA
- Where
- Thailand
- Volunteers
- 160 people
- Sponsor
- Khon Kaen University