Clinical trials: Post Operative Patients
Acute Brain Injury, Post-neurosurgical Status
High-Flow Nasal Cannula After Extubation in Acute Brain Injury
Patients with acute brain injury after neurosurgery are at increased risk of extubation failure after removal of the endotracheal tube.
- Conditions
- Acute Brain Injury, Post-neurosurgical Status, Extubation Failure, Postoperative Respiratory Complications
- Trial name
- NCT07664085
- Where
- Vietnam
- Volunteers
- 285 people
- Sponsor
- Bach Mai Hospital
Hemoglobins, Albumins
Association Between Preoperative HALP and Immediate Postoperative Outcomes
Multiple inflammation-based prognostic scores have been developed for the prediction of perioperative morbidity and mortality following pancreaticoduodenectomy (PD).
- Conditions
- Hemoglobins, Albumins, Platelets, Lymphocytes
- Trial name
- NCT05506748
- Testing
- pantients undergoing pancreaticoduodenectomy
- Where
- Nepal
- Volunteers
- 22 people
- Sponsor
- Chitwan Medical College
Cleft Palate, Cleft Lip
Perioperative Respiratory Adverse Events in Cleft Lip and Palate Surgery: Incidence, Risk Factors, and Clinical Scoring
Cleft lip and palate surgeries present unique anesthetic challenges due to shared airway access with the surgical field, frequent anatomical abnormalities, and a predominantly infant and toddler population.
- Conditions
- Cleft Palate, Cleft Lip, Laryngospasm, Bronchospasm
- Trial name
- NCT07651904
- Testing
- Standard General Anesthesia per Institutional Protocol
- Volunteers
- 150 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Benign Prostatic Hyperplasia, Post-Op Complication
Artery Embolization vs Operation of Benign Prostate Hyperplasia
Aim of the study is to compare prostate artery embolization (PAE) to the established surgical treatment for patient acceptance, morbidity, complications, and the functional outcomes.
- Conditions
- Benign Prostatic Hyperplasia, Post-Op Complication, Embolization Therapeutic, Transurethral Resection of Prostate Syndrome
- Trial name
- NORTAPE (NCT04084938)
- Testing
- Prostate operation or prostate artery embolization
- Where
- Norway
- Volunteers
- 140 people
- Sponsor
- Oslo University Hospital
Critical Illness, Pediatrics
Effect of Giving Reduced Fluid in Children After Trauma
This study is designed to help decide how much intravenous (IV) fluid should be given to pediatric trauma patients. No standard currently exists for managing fluids in critically ill pediatric trauma patients, and many fluid…
- Conditions
- Critical Illness, Pediatrics, General Surgery, Fluid Therapy
- Trial name
- NCT04201704
- Testing
- Balanced crystalloid solution volume administration, Packed Erythrocytes Units, Blood Product Unit volume, Plasma volume
- Where
- 4 sites in United States
- Volunteers
- 250 people
- Sponsor
- Columbia University
ERAS, Gall Bladder Disease
ERAS After Cholecystectomy in Kigali, Rwanda
Enhanced Recovery After Surgery (ERAS) pathway represents a peri-operative multimodal management aiming at a decrease in surgical aggression and an improved patient rehabilitation, in order to reduce postoperative morbidity…
- Trial name
- NCT05516056
- Testing
- ERAS clinical pathway
- Where
- Rwanda
- Volunteers
- 50 people
- Sponsor
- Olivier Detry MD PhD
Tracheal Stenosis
Investigation of the Effect of Systemic Steroids on Treatment and Prevention of Recurrent Tracheal Stenosis in Postoperative Patients
tracheal stenosis is the result of abnormal wound-healing processes leading to hypertrophic scar formation and obstruction of the airway lumen by excess granulation tissue.
- Trial name
- NCT02855502
- Testing
- Prednisolone
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- National Research Institute of Tuberculosis and Lung Disease, Iran
Adenotonsillectomy, Children
Intranasal Dexmedetomidine-esketamine Administration and Postoperative Pain in Pediatric Patients
Postoperative pain after adenoid and tonsil surgery is significant, with approximately 75% of pediatric patients experiencing severe postoperative pain.
- Conditions
- Adenotonsillectomy, Children, Intranasal Administration, Dexmedetomidine
- Trial name
- NCT07479602
- Testing
- Intranasal dexmedetomidine-esketamine
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Peking University First Hospital
Emergency General Surgery Laparotomy
Surgical Apgar Score for Identifying Patients Who May Need Intensive Care After Emergency Abdominal Surgery
This prospective observational study will evaluate whether the Surgical Apgar Score can help identify patients who require direct admission to the intensive care unit after emergency abdominal surgery.
- Trial name
- SAS-ICU (NCT07814131)
- Where
- Pakistan
- Volunteers
- 77 people
- Sponsor
- King Edward Medical University
Bladder Cancer, Urethral Cancer
Combination Chemotherapy in Treating Patients With Bladder Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00003701
- Testing
- carboplatin, cisplatin, doxorubicin hydrochloride
- Where
- 13 sites in United States
- Volunteers
- 490 people
- Sponsor
- Eastern Cooperative Oncology Group
Myocardial Infarction, Reperfusion Injury
Pilot Study of Edaravone to Treat Acute Myocardial Infarction
Early reperfusion therapy has improved the clinical outcomes of patients with acute myocardial infarction (AMI), but these benefits are limited in some patients by reperfusion injuries.
- Trial name
- NCT00265239
- Testing
- edaravone
- Where
- Japan
- Volunteers
- 104 people
- Sponsor
- Kumamoto University
Surgical Site Infection
Neutrophil Phenotypic Profiling and Surgical Site Infections in Surgical Patients
Surgical site infections (SSIs) are one of the major hospital acquired infections and responsible for the most cost among the hospital acquired infections.
- Trial name
- NCT04773457
- Testing
- Surgical Site Infection
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Boston Children's Hospital
Lung Injury, Postoperative Complications
Ventilation During Cardiopulmonary Bypass
Postoperative pulmonary dysfunction (PPD) is a widely reported complication of cardiopulmonary bypass (CPB) although there is improvement in perioperative management, that leads to increased morbidity and mortality in cardiac…
- Conditions
- Lung Injury, Postoperative Complications, Pulmonary Collapse
- Trial name
- NCT04962542
- Testing
- ventilation
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Gastrointestinal Stromal Tumors
Preoperative and Postoperative Imatinib Mesylate Study in Patients With c-Kit Positive GIST
Primary objectives 1. To determine whether induction of apoptosis or inhibition of angiogenesis are involved in the antitumor activity of (Gleevec, Formerly STI-571) in patients with gastrointestinal stromal tumors (GIST) as…
- Trial name
- NCT00500188
- Testing
- Imatinib Mesylate (Gleevec)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- M.D. Anderson Cancer Center
Complete Contact, Incomplete Contact
Comparison of Post-operative Knee Range of Motion and Functions Between Intraoperative Complete and Incomplete Patellofemoral Articular Contacts in Patients Undergoing Total Knee Arthroplasty
The purpose of this study is to compare clinical outcome in knee range of motion and functions between intraoperative complete and incomplete patellofemoral articular contacts
- Trial name
- NCT05349461
- Testing
- Complete patellofemoral articular contact, Incomplete patellofemoral articular contact
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Navamindradhiraj University
Pain
Intravenous Lidocaine for Post-Tonsillectomy Pain in Pediatric Patients
The purpose of this study is to determine whether giving lidocaine intravenously during and after a tonsillectomy surgery is effective in decreasing postoperative pain.
- Trial name
- NCT02595463
- Testing
- Lidocaine, Saline
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Postoperative Pain
Perfusion Index as an Objective Measure for Postoperative Pain Assessment in Pediatric Patients.
It has been demonstrated that infants and children experience pain in a similar manner to adults, however it used to be undertreated when compared to adult.
- Trial name
- NCT03854604
- Testing
- postoperative pain assessment
- Where
- 3 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Atelectasis, Block
Effect Posterior QLB on Atelectasis
We aimed to investigate the effect of posterior quadratus lumborum block on postoperative atelectasis in inguinal hernia surgery in pediatric patients.
- Conditions
- Atelectasis, Block, Pediatrics, Quadratus Lumborum Block
- Trial name
- NCT04830280
- Testing
- posterior quadratus lumborum block
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Lower Lip Tissue Loss, Cancer
Functional and Aesthetic Outcomes Following Lower Lip Reconstruction
This retrospective study, aims to evaluate the functional and aesthetic results of lower lip reconstructions, incorporating both patient experiences and the analysis of physicians and surgeons working on facial issues (plastic…
- Trial name
- REFEPLI (NCT07298070)
- Testing
- Patient-Reported Outcome Questionnaire (post-operative)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hôpital NOVO
Emergence Agitation
Efficacy of Low Dose Propofol Given at the End of Sevoflurane Anesthesia for Prevention of Emergence Agitation in Pediatric Patient Undergoing MRI Scan
The goal of this clinical trial is to compare Efficacy of low dose propofol(0.5 mg/kg) vs placebo given at the end of sevoflurane anesthesia for prevention of emergence agitation in pediatric patient undergoing MRI scan.
- Trial name
- NCT06218680
- Testing
- Propofol, Normal saline
- Where
- Thailand
- Volunteers
- 134 people
- Sponsor
- Khon Kaen University