Clinical trials: Post Operative Wound Infection
Appendicitis
Role of Wound Irrigation After Appendectomy
Surgical site infection is a common problem after open appendectomy. Irrigation of the surgical wound by topical antibiotics has been devised as a measure to reduce the incidence of wound infection.
- Trial name
- NCT03773224
- Testing
- Irrigation
- Where
- Egypt
- Volunteers
- 179 people
- Sponsor
- Mansoura University
Incisional Surgical Site Infections
Total Occlusive Ionic Silver-containing Dressing vs Mupirocin Ointment Application vs Conventional Dressing in Elective Colorectal Surgery: Effect on Incisional Surgical Site Infection
The patients were randomized into 3 groups: those patients undergoing a ionic silver-containing dressing (ISD) (Group 1), those undergoing a Mupirocin ointment application (MOA) (Group 2) and those using a conventional dressing…
- Trial name
- NCT02267122
- Testing
- ionic silver-containing dressing, Mupirocin ointment application
- Volunteers
- 147 people
- Sponsor
- Hospital General Universitario Elche
Acute Appendicitis, Acute Cholecystitis
Web-based International Register of Emergency Surgery and Trauma
The WIRES-T project (Web-based International Registry of Emergency General Surgery and Trauma) has been set up to allow to all the EGS (Emergency General Surgery) and Trauma surgeons to register their activity and to obtain a…
- Conditions
- Acute Appendicitis, Acute Cholecystitis, Acute Diverticulitis, Post-operative Complications
- Trial name
- WIRES-T (NCT03643718)
- Testing
- Emergency General Surgery
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Surgical Site Infection, Post-Op Infection
Analysis of Risk Factors for Surgical Site Infections in Patients With Acute Abdomen at Hospital of State University of Haiti
The purpose of this study is to identify the risk factors associated with surgical site infection.
- Trial name
- NCT06480344
- Where
- Haiti
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Haiti
Wound Infection, Wound Dehiscence
Honey Dressing - A Preventive Procedure for Post-Surgical Site Infection.
The goal of this clinical trial is to compare the wound healing in the participants who underwent the clean surgical procedure, by applying honey dressing and common Iodine solution dressing, participants will have no other…
- Conditions
- Wound Infection, Wound Dehiscence, Wound Bleeding, Wound Surgical
- Trial name
- NCT06220344
- Testing
- Honey Dressing, Iodine Dressing
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- HITEC-Institute of Medical Sciences
Surgical Site Infection
Study of the Incidence of Surgical Site Infections Developed by Patients Hospitalized in the Wards of a Large Teaching Hospital in Rome, Italy
The surgical departments of the hospital were included in the study on a rotational basis over a period of 5 months. All patients undergoing surgery during this period were enrolled in the study.
- Trial name
- NCT05788575
- Testing
- surgery
- Where
- Italy
- Volunteers
- 5,424 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Surgical Site Infection (SSI), Spine Diseases
Efficacy of Intrawound Vancomycin in Spine Surgery
"This multicenter, prospective, time-cluster randomized controlled trial with blinded endpoint assessment (PROBE design) evaluated the efficacy of intrawound vancomycin powder (2 g) in preventing surgical site infections (SSI)…
- Trial name
- NCT07866157
- Testing
- vancomycin, Standard surgical closure
- Where
- Egypt
- Volunteers
- 416 people
- Sponsor
- Ain Shams University
Inguinal Hernia, Hydroceles
Prevention of Surgical Site Infection in Open Paediatric Groin Surgeries Using Intravenous Prophylactic Antibiotics and Antimicrobial-coated Sutures
The goal of this clinical trial is to learn if the use of prophylactic antibiotics and antimicrobial-coated sutures can prevent surgical site infection in children undergoing open groin surgeries.
- Conditions
- Inguinal Hernia, Hydroceles, Surgical Site Infection
- Trial name
- NCT07346742
- Testing
- Antimicrobial-coated sutures, Intravenous Cefuroxime
- Where
- Nigeria
- Volunteers
- 174 people
- Sponsor
- Olawumi Olajide
Ceserean Section, Lower Limb Fractures
Infection Prevention for "Bellwether" Surgery in Ethiopia
The study examines surgical site infections and antimicrobial resistance following life-saving surgeries like C-sections and leg fracture repairs in Ethiopia.
- Conditions
- Ceserean Section, Lower Limb Fractures, Surgical Site Infection (SSI)
- Trial name
- NCT07647796
- Testing
- Surgical Site Infection Prevention and Control (IPC) Bundle
- Where
- Ethiopia
- Volunteers
- 1,000 people
- Sponsor
- Karolinska Institutet
Surgical Site Infection
Subcutaneous Tissue Irrigation With Povidone Iodine in Decreasing the Rate of Surgical Site Infection Following Cesarean Section
This study aims to assess the efficacy of Povidone Iodine (Betadine®) irrigation of subcutaneous tissue prior to skin closure in reducing the incidence of surgical site infection after elective caesarean section and post…
- Trial name
- NCT03549702
- Testing
- Povidone iodine 1% solution
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Surgical Wound Infection
Determining the Worldwide Epidemiology of Surgical Site Infections After Gastrointestinal Surgery
Surgical site infection (SSI) is the most common complication following major gastrointestinal surgery, affecting between 25-40% of patients.
- Trial name
- GlobalSurg 2 (NCT02662231)
- Testing
- Emergency, or elective gastrointestinal resection
- Where
- 2 sites in United Kingdom
- Volunteers
- 12,539 people
- Sponsor
- University of Edinburgh
Surgical Site Infections, Hypothermia
Feedback on Perioperative Temperature Management and Patient Outcomes: Three-arm Trial to Compare Feedback
The investigators aim to assess the impact of benchmarked and ranked feedback on anesthesiologists' perioperative temperature management and subsequent patient outcomes.
- Trial name
- NCT02414191
- Testing
- Benchmarked Feedback, Ranked Feedback
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Surgical Site Infection, Colorectal Cancer
Prophylatic Effect Preoperative Antibiotics With Mechanical Bowel Preparation in SSIs: A Propensity Analysis
Surgical site infections (SSIs) are a major postoperative complication after colorectal surgery. Current study aims to evaluate prophylactic function of oral antibiotic intake (OA) in combination with mechanical bowel preparation…
- Trial name
- NCT04258098
- Testing
- Oral antibiotics ( Streptomycin ,metronidazole )
- Volunteers
- 806 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Surgical Site Infection, Closed Suction Drains
Bacterial Colonization of Suction Drains Following Spine Surgery
Closed suction drains are commonly used following surgery, if the wound is expected to discharge significant amounts of fluid. To this date, no evidence base exists as to the exact post operative time period or discharge volume…
- Trial name
- NCT01803490
- Where
- Israel
- Volunteers
- 224 people
- Sponsor
- Western Galilee Hospital-Nahariya
Cardiac Surgery, Bone Wax, NU-KNIT, Median Sternotomy, Deep Sternal Wound Infection, Surgical Site Infection
Surgicel NU-KNIT Vs Bone Wax on Median Sternotomy
Bone wax is traditionally used as part of surgical procedures to prevent bleeding from exposed spongy bone. It is an effective hemostatic device which creates a physical barrier.
- Trial name
- NBCS (NCT06869772)
- Testing
- Closure of sternotomy
- Where
- Qatar
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Endometritis, Wound Infection
Study of Effectiveness and Safety of Azithromycin-based Extended-spectrum Prophylaxis to Prevent Post Cesarean Infection
The Cesarean Section Optimal Antibiotic Prophylaxis (C/SOAP) study is a large pragmatic multi-center randomized clinical trial designed to evaluate the comparative effectiveness and safety of azithromycin-based extended-spectrum…
- Conditions
- Endometritis, Wound Infection, Abscess, Surgical Site Infection
- Trial name
- C/SOAP (NCT01235546)
- Testing
- Azithromycin and standard of care
- Where
- 9 sites in United States
- Volunteers
- 2,013 people
- Sponsor
- Alan Tita
Abdominal Hernia
Light vs Heavy Weighted Mesh Repair in Primary Abdominal Hernia in Terms of Surgical Site Infection
This study compares the incidence of surgical site infections (SSI) in patients undergoing abdominal hernia repair using either light or heavy-weighted polypropylene mesh.
- Trial name
- NCT06644612
- Testing
- Light Weight Mesh, Heavy Weight Mesh
- Where
- Pakistan
- Volunteers
- 106 people
- Sponsor
- Khyber Medical University Peshawar
Surgical Site Infection
Gaps Between Evidence and Practice in Prevention of Surgical Site Infection in Spain
Web-based survey to members of 10 Spanish Associations of surgical nurses and surgeons of different specialities to know the application of preventative measures for surgical site infection.
- Trial name
- SurveyOIC (NCT04310878)
- Testing
- Survey among perioperative nurses and surgeons
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Hospital de Granollers
Surgical Scrubbing, Surgical Site Infection
Surgical Hand Scrubbing Methods and the Duration of Scrubbing Time
Surgical hand scrubbing is the removal of transient flora and reduction of permanent flora as much as possible before any sterile gloves are worn before any surgical intervention.
- Trial name
- NCT04579705
- Testing
- Using a brush
- Where
- Turkey (Türkiye)
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Surgical Site Infection, Sternal Wound Infection
Sternal Wound and Aortic Graft (SWAG), an Observational Cohort Study.
The aim of this study is to systematically explore the perioperative presence of P acnes in all layers of sternal wound incision as well as contamination of graft material and prosthetic valves during primary operation.
- Trial name
- SWAG (NCT04592328)
- Testing
- Bacterial cultures taken during surgery.
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Örebro County