Clinical trials: Post Partum Depression, open to volunteers
High-risk Pregnancy, Hospitalization
LLM-Generated Medical Summaries During Hospitalization to Improve Patient Activation in High-Risk Pregnancies
The goal of this clinical trial is to learn if AI-generated medical summaries help hospitalized pregnant participants better understand and actively participate in their own care.
- Conditions
- High-risk Pregnancy, Hospitalization, Patient Activation, Artificial Intelligence (AI)
- Trial name
- NCT07823517
- Testing
- LLM-Generated Medical Summaries
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Sheba Medical Center
Depression, Postpartum, Postpartum Depression (PPD)
Brexanolone Lifting Outcomes Of Moms
The purpose of this research study is to test the study drug, LPCN 1154A, as a possible treatment for postpartum depression (PPD).
- Conditions
- Depression, Postpartum, Postpartum Depression (PPD), Post-partum Depression, Postnatal Depression
- Trial name
- BLOOM (NCT07822321)
- Testing
- LPCN 1154A
- Where
- 16 sites in United States
- Volunteers
- 120 people
- Sponsor
- Lipocine Inc.
Depression, Anxiety, Antenatal Depression
Integration of Stepped Care for Perinatal Mood and Anxiety Disorders Among Women Attending MCH Clinics
Perinatal mood and anxiety disorders (PMAD), defined as depression and anxiety during pregnancy or up to 1 year postpartum, account for substantial morbidity and mortality among birthing people globally especially in low- and…
- Conditions
- Depression, Anxiety, Antenatal Depression, Postnatal Depression
- Trial name
- IPMH (NCT06456307)
- Testing
- Integrated Perinatal Mental health program (systematic screening for PMAD, PM+ and tele-psychiatry)
- Where
- 2 sites in Kenya
- Volunteers
- 2,970 people, healthy volunteers welcome
- Sponsor
- Kenyatta National Hospital
Depression - Major Depressive Disorder
Development of Attentional Biases for Affective Cues in Infants of Mothers With Depression
The goal of this study is to examine attentional biases for facial displays of emotion as a mechanism of risk in infants of mothers with postpartum major depression, and the potential role of infant arousal in the development of…
- Trial name
- NCT06835855
- Testing
- Passive Viewing Task, Interaction Task
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Binghamton University
Prenatal Depression, Mental Health Related Quality of Life
Technology Supported Mindfulness for Prenatal Depression and Mental Health-related Quality of Life in a Resource-Limited Environment
The goal of this clinical trial is to learn if a video-guided mindfulness intervention can improve prenatal depression symptoms, improve mental health-related quality of life, reduce the risk of maternal postpartum depression and…
- Conditions
- Prenatal Depression, Mental Health Related Quality of Life, Maternal Postpartum Depression, Paternal Postpartum Depression
- Trial name
- NCT07151781
- Testing
- Video-guided Mindfulness Exercise
- Where
- Ethiopia
- Volunteers
- 120 people
- Sponsor
- Bekelu Teka Worku
Perinatal Mental Health, Gestational Weight Gain
Healthy Adaptation to Pregnancy, Postpartum and Parenthood
Healthy Adaptation to Pregnancy, Postpartum and Parenthood (HAP3) The HAP3 study is evaluating a new digital support program for pregnant women and their partners.
- Conditions
- Perinatal Mental Health, Gestational Weight Gain, Postpartum Weight Retention, Child Development
- Trial name
- HAP3 (NCT07837193)
- Testing
- HAP3 Family App
- Where
- Belgium
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Low Birth Weight, Kangaroo Mother Care
Admission to Kangaroo Mother Care (KMC) Ward and Maternal Postpartum Depression
The goal of this clinical trial is to learn if extended admission to the Kangaroo Mother Care (KMC) ward helps to prevent postpartum depression in mothers of low birthweight infants in a low-resource setting whose newborns were…
- Conditions
- Low Birth Weight, Kangaroo Mother Care, Postpartum Depression, Neurodevelopmental Outcome
- Trial name
- KMC PPD (NCT06545760)
- Testing
- Kangaroo mother care (KMC) support for > 2 days, Kangaroo mother care (KMC) support for < 2 days
- Where
- Zambia
- Volunteers
- 1,908 people
- Sponsor
- University of Alabama at Birmingham
Depression, Posttraumatic Stress Disorder
Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa
Pregnant women in South Africa (SA) are at high risk of HIV acquisition. Pre-exposure prophylaxis (PrEP) use during pregnancy is both safe and effective in preventing HIV.
- Conditions
- Depression, Posttraumatic Stress Disorder, Pregnancy Related, Medication Adherence
- Trial name
- NCT05624931
- Testing
- Brief CBT-Based Intervention, Enhanced Treatment as Usual
- Where
- 2 sites in United States, South Africa
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Mental Health, Physical Health
Parental Well-being After Childbirth in Switzerland
Improving maternal and child health is a global priority, with increasing emphasis on ensuring women and their families not only survive but also thrive after childbirth.
- Conditions
- Mental Health, Physical Health, Postpartum, Parents
- Trial name
- SOCRATES (NCT06886841)
- Where
- 2 sites in Switzerland
- Volunteers
- 4,200 people
- Sponsor
- Laurent Gaucher
Postpartum Depression
Engage & Connect: A Psychotherapy for Postpartum Depression
This randomized controlled trial compares a novel psychotherapy, Engage \& Connect, with a Symptom Review and Psychoeducation intervention, tailored to reduce postpartum depression.
- Trial name
- NCT05585164
- Testing
- Engage & Connect (E&C), Symptom Review and Psychoeducation (SRP)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Weill Medical College of Cornell University
Development and Health, Nutrition
Effects of Light Exposure for Postpartum Depression on Infant Development
About 11% of women develop depression and anxiety after giving birth. These symptoms can reduce a mother's quality of life and daily functioning and may negatively affect her child's growth and development.
- Trial name
- Chrono_Baby (NCT07440355)
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
HIV, HIV - Human Immunodeficiency Virus
Intervention to Reduce HIV Related Stigma Among Pregnant and Postpartum Women
Purpose of this Study: The main purpose of this study is to adapt an existing evidence-based intervention, Project Accept Post-Test Support Services (PTSS) Module 3, specifically for pregnant and postpartum women living with HIV…
- Conditions
- HIV, HIV - Human Immunodeficiency Virus, Postpartum, Pregnancy
- Trial name
- WAT (NCT07064928)
- Testing
- Adapted Project Accept's Post-Test Support Services (PTSS) Module 3
- Where
- Ghana
- Volunteers
- 163 people
- Sponsor
- University of California, San Francisco
Perinatal Depression
Early Detection of Perinatal Depression With Wearable Technology
The goal of this feasibility study is to learn whether wearable devices and self-report surveys can help researchers better understand changes in mood during pregnancy and after birth in young pregnant individuals with a history…
- Trial name
- BLUESMAPPED (NCT07784244)
- Testing
- Oura Ring (Photoplethysmography-based wearable ring), EmbracePlus Watch (Electrodermal activity wristband sensor)
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Women's College Hospital
Neurodevelopmental Disorders
5-Year Follow-up of Children and Mother After Expectant Management Versus Induction of Labor in Low-risk Nulliparous Women at 39 Weeks of Gestation
In France, the rate of labor induction has markedly increased in recent years, partly following the ARRIVE trial suggesting short-term benefits of elective induction at 39 weeks in low-risk nulliparous women.
- Trial name
- FAMILY-FA (NCT07330336)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 4,200 people
- Sponsor
- University Hospital, Bordeaux
Stress Disorders, Post-Traumatic, Premature Birth
Postpartum Care in the NICU (PeliCaN) Transitions
This is a randomized controlled trial of a dyad-centered, doula support and healthcare coordination model of care in a large urban neonatal intensive care unit (NICU), which serves a high-risk, low-income, majority Black…
- Conditions
- Stress Disorders, Post-Traumatic, Premature Birth, Postpartum Depression, Postpartum Anxiety
- Trial name
- PeliCaN (NCT06521398)
- Testing
- Doula Support
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania
Postpartum Depression, Postpartum Anxiety
The Mom and Infant Outcomes (MOMI) Study
The investigator's long-term goal is to mitigate pregnancy-related mortality (PRM) risk by systematically delivering scalable integrated clinical and supportive care that is effective for all.
- Conditions
- Postpartum Depression, Postpartum Anxiety, Cardiometabolic Syndrome
- Trial name
- NCT06277661
- Testing
- MOMI PODS, Enhanced Usual Care (EUC)
- Where
- United States
- Volunteers
- 384 people
- Sponsor
- Ohio State University
Pregnancy, Post Partum
Deconstructing Maternal Burdens: Doulas and the Community Unite for Health
This study is a randomized controlled trial comparing two models of doula support for pregnant individuals enrolled in Medicaid: an enhanced doula support model, in which support starts earlier in pregnancy, occurs more…
- Conditions
- Pregnancy, Post Partum, Doula Care, Postpartum Depression (PPD)
- Trial name
- UNITE (NCT07799805)
- Testing
- Doula, Standard (non-enhanced) Medicaid doula support
- Where
- United States
- Volunteers
- 516 people
- Sponsor
- University of Florida
Postpartum Depression (PPD)
Salutogenesis and Self-efficacy-based Childbirth Education Programme for Preventing Postpartum Depression
Although the transition to motherhood is often a joyful experience, there is evidence that teenage motherhood can present many stressful challenges, potentially leading to the development of postpartum depression.
- Trial name
- NCT06698107
- Testing
- Childbirth education programme, Usual Care
- Where
- 4 sites in Ethiopia
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Post Partum, Maternal Depression
Pilot Feasibility Study With Doulas
The purpose of this study is to determine whether an existing evidence-based intervention, You Matter, can be delivered with fidelity by doulas at their community clinic, MAAME, Inc.
- Conditions
- Post Partum, Maternal Depression, Maternal Depression and Parent Practices, Postpartum
- Trial name
- NCT07614789
- Testing
- YouMatter
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Infant Admitted to Neonatal Intensive Care Unit (NICU)
The Effects of a Caregiver-initiated Reading Intervention to Their Infant in the Neonatal Intensive Care Unit
The purpose of this study is to investigate the impact of a caregiver-initiated reading intervention to their infant, in the Neonatal Intensive Care Unit (NICU), on the caregiver-infant dyad, both during hospitalization and…
- Trial name
- NCT07789145
- Testing
- Reading Intervention
- Volunteers
- 120 people
- Sponsor
- University of Texas Southwestern Medical Center