Clinical trials: Post Partum Haemorrhage
Post Partum Hemorrhage
Sublingual Misoprostol in Reduction of Caesarean Blood Loss
Caesarean delivery is inevitably associated with a higher amount of blood loss vis-à-vis primary postpartum haemorrhage, when compared to vaginal delivery.
- Trial name
- SUMIROCBLOL (NCT05532215)
- Testing
- Misoprostol, Oxytocin
- Where
- Nigeria
- Volunteers
- 152 people
- Sponsor
- OZORI EBIOGBO STANLEY
Uterine Atony, Postpartum Hemorrhage
Oxytocin Regimen to Prevent Atony and Postpartum Hemorrhage During Vaginal Delivery: 3-arm RCT
This is a double-blind 3-arm randomized clinical trial to determine whether higher dose oxytocin regimens (compared to the standard regimen) reduce the frequency of uterine atony and postpartum hemorrhage after vaginal delivery.
- Trial name
- NCT00790062
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 1,798 people
- Sponsor
- University of Alabama at Birmingham
Postpartum Hemorrhage, Cesarean Section Complications
The Impact of Mechanical Methods on the Postpartum Haemorrhage Prophylaxis During Caesarean Section
The rate of heavy blood loss is higher in Cesarean delivery compared to vaginal deliveries. Since postpartum hemorrhage is a life threatening situation to decrease the maternal mortality and morbidity rates, precautions should be…
- Trial name
- NCT05948436
- Testing
- Clamping the uterine artery bilaterally during Cesarean section
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Teaching Innovation, Midwifery Students Education
Flipped Learning in PPH Education: Impact on Midwifery Students' Knowledge, Skills, Self-Efficacy, and Satisfaction
Maternal death refers to a woman's death due to direct or indirect causes during pregnancy, childbirth, or within 42 days postpartum.
- Conditions
- Teaching Innovation, Midwifery Students Education, Postpartum Hemorrhage, Flipped Classroom Model in Teaching
- Trial name
- NCT06861296
- Testing
- Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Postpartum Hemorrhage
The Efficacy of Tranexamic Acid in Preventing Postpartum Haemorrhage After Caesarean Section
This study seeks to determine if the using tranexamic acid prophylactically at caesarean section will prevent postpartum haemorrhage which is a major cause of maternal mortality in Zimbabwe and globally.
- Trial name
- ETAPPH (NCT04733157)
- Testing
- Tranexamic acid injection
- Where
- 2 sites in Zimbabwe
- Volunteers
- 1,226 people
- Sponsor
- University of Zimbabwe
Postpartum Hemorrhage
Effect of Prophylactic Administration of Oxytocin in Uniject™ on Postpartum Hemorrhage at Home Births in Ghana
This study is designed to test the hypothesis that the intramuscular administration of 10 IU of oxytocin in Uniject™ during the third stage of labor by a Community Health Officer (CHO) at home births in Ghana will reduce the risk…
- Trial name
- NCT01108289
- Testing
- Oxytocin in Uniject
- Where
- Ghana
- Volunteers
- 1,586 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Post Partum Hemorrhage
Bilateral Uterine Artery Ligation in Reducing Incidence of Postpartum Hemorrhage in Cesarean Section
The patients were recruited from women attending labor ward to undergo cesarean section.
- Trial name
- NCT03591679
- Testing
- Oxytocin, bilateral uterine artery ligation
- Where
- Egypt
- Volunteers
- 1,070 people
- Sponsor
- Assiut University
Obstetric and Perinatal Complications, Postpartum Hemorrhage
A Skills and Drills Intervention for Emergency Obstetrics and Neonatal Care at First Referral Units of North Karnataka
To evaluate the effectiveness of a First Referral Unit (FRU) Emergency Obstetric and Newborn Care (EmONC) skills and drills intervention, to estimate the appropriateness and effectiveness of referrals in intervention arm compared…
- Conditions
- Obstetric and Perinatal Complications, Postpartum Hemorrhage, Preeclampsia/Eclampsia, Obstructed/Prolonged Labor
- Trial name
- NCT01865656
- Testing
- Skills training, Emergency obstetric drills, Revised Case Sheets
- Volunteers
- 15,018 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Postpartum Hemorrhage
Feasibility Trial of the Circumferential Abdominal Pelvic Pressure Device (CAPP)
A group of midwives and obstetric nurses have been trained to use circumferential abdominal pelvic pressure (CAPP) to treat postpartum hemorrhage.
- Trial name
- NCT01497756
- Testing
- CAPP use
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of New Mexico
Postpartum Hemorrhage \(PPH\)
Comparison of the Effect of Carbetocin Versus Oxytocin in the Prevention of Postpartum Hemorrhage After Emergency Caesarean Section in Antenatal Low-risk Patients
This study will be conducted to compare the effects of pabal and oxytocin administered to prevent postpartum hemorrhage in patients who were followed in the delivery room due to vaginal labor but underwent cesarean section due to…
- Trial name
- EMERGE-CS (NCT07380529)
- Testing
- Carbetocin, Oxytocin
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Postpartum Hemorrhage
Misoprostol and Oxytocin in Uniject® for Postpartum Hemorrhage Prevention in Communities
This community-based cluster Randomised Control Trial will assess the feasibility, cost, risks and benefits of use of oral Misoprostol and parenteral Oxytocin in Uniject® as prophylaxis for postpartum hemorrhage (PPH) in…
- Trial name
- NCT01710566
- Testing
- Misoprostol, Oxytocin
- Sponsor
- Gynuity Health Projects
Nurse Education, Nursing Students
The Effectiveness of Serious Game-Based Training for Nursing Students in Postpartum Haemorrhage Management
This randomized controlled trial evaluated the incremental effect of adding a web-based serious game to standard theoretical instruction on third-year nursing students' postpartum hemorrhage management knowledge, task-specific…
- Conditions
- Nurse Education, Nursing Students, Postpartum Hemorrhage, Nursing Care
- Trial name
- NCT07229573
- Testing
- Web-Based Serious Game
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Umbilical Cord
Timing of Umbilical Cord Clamping: One to Three Minutes vs. After Cessation of Cord Pulsation
The timing of umbilical cord clamping has been widely discussed in the scientific community. As part of the worldwide strategies to reduce childhood iron deficiency anemia, the incorporation of late clamping (at least one minute…
- Trial name
- CORD (NCT03844490)
- Testing
- CESSATION OF CORD PULSE, CONTROL
- Where
- Brazil
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Postpartum Hemorrhage
The Association Between Shock Index and Severity of Postpartum Blood Loss
The present study aims to determine the relationship between postpartum changes in the shock index and the severity of blood loss and other PPH results.
- Trial name
- NCT03135158
- Testing
- Exposure to vaginal delivery
- Where
- Colombia
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Postpartum Hemorrhage
RUBY Post-Market Registry on the Jada® System
The RUBY Study is a multicenter, observational, post-market registry designed to collect observational data on patients treated with the Jada System in the post-market setting.
- Trial name
- RUBY (NCT04995887)
- Testing
- Jada® System
- Where
- 16 sites in United States
- Volunteers
- 809 people
- Sponsor
- Alydia Health
Postpartum Hemorrhage, Anemia
Misoprostol for the Prevention of Postpartum Hemorrhage in Rural Pakistan
This community-based trial will study misoprostol for the prevention of postpartum hemorrhage in rural Pakistan. Traditional birth attendants assisting home deliveries will administer study tablets (600 mcg oral misoprostol or…
- Trial name
- NCT00120237
- Testing
- Misoprostol
- Where
- Pakistan
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Pregnancy Hemorrhage, Postpartum Hemorrhage
Implementation of the NPMS Obstetric Hemorrhage Bundle at a Tertiary Center: Utilization of the Delphi Method
The National Partnership for Maternal Safety (NPMS) developed an obstetric hemorrhage consensus bundle to provide every United States birthing facility consistent, validated practice guidelines.
- Trial name
- NCT03018119
- Testing
- Survey
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Sepsis, Pneumonia
Improved Accessibility of EmONC Services for Maternal and Newborn Health: a Community Based Project
The purpose of this study is to determine whether an integrated EmONC package (community mobilization, training of community-based health care providers and a maternal and neonatal health pack) reduce perinatal and neonatal…
- Conditions
- Sepsis, Pneumonia, Omphalitis, Birth Asphyxia
- Trial name
- EmONC (NCT01751945)
- Testing
- EmONC package
- Where
- Pakistan
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Postpartum Hemorrhage
IV vs IM Oxytocin in the Third Stage of Labor for Prevention of Postpartum Hemorrhage
The study will evaluate whether prophylactic oxytocin administered in the third stage of labor via IV infusion results in a lower mean blood loss compared to IM injection.
- Trial name
- NCT01608958
- Testing
- Oxytocin
- Where
- 3 sites in Ecuador, Turkey (Türkiye) and 1 more
- Volunteers
- 653 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Postpartum Hemorrhage, Venous Thromboembolism
Timing of Thromboprophylaxis After Postpartum Hemorrhage
Postpartum hemorrhage is a leading cause of maternal morbidity and mortality worldwide. Women who experience severe postpartum hemorrhage are at increased risk of both recurrent bleeding and venous thromboembolism.
- Conditions
- Postpartum Hemorrhage, Venous Thromboembolism, Pulmonary Embolism, Deep Vein Thrombosis
- Trial name
- NCT07689136
- Testing
- Pharmacologic Thromboprophylaxis
- Where
- Tunisia
- Volunteers
- 236 people
- Sponsor
- University Tunis El Manar