Clinical trials: Post-Tonsillectomy
Sleep-disordered Breathing, Obstructive Sleep Apnea
Comparison of Sleep Study Results After Partial Intracapsular Tonsillectomy Versus Total Tonsillectomy
The purpose of this study is to demonstrate similar improvements in sleep-disordered breathing as determined by sleep study with microdebrider-assisted partial intracapsular tonsillectomy and adenoidectomy versus total Bovie…
- Trial name
- NCT00887471
- Testing
- PITA or T&A
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- State University of New York - Downstate Medical Center
Sleep Apnea, Obstructive, Sleep Apnea Syndromes
Continuous Positive Airway Pressure (CPAP) After Adenotonsillectomy in Children
Obstructive sleep-disordered breathing (SDB) affects 2-3% of children and may lead to problems with nighttime sleep and daytime behavior, learning, sleepiness, and mood.
- Conditions
- Sleep Apnea, Obstructive, Sleep Apnea Syndromes, Child Behavior Disorders, Attention Deficit Disorder With Hyperactivity
- Trial name
- NCT01554527
- Testing
- CPAP treatment, No CPAP treatment
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Michigan
Laryngopharyngeal Reflux, Throat Pain
Anti-reflux Control to Decrease Post Tonsillectomy Pain
The study aims to determine if treating pediatric patients (age 7-17) for four weeks with omeprazole prior to tonsillectomy will decrease post tonsillectomy pain.
- Trial name
- NCT01777854
- Testing
- Omeprazole
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Ascension Health
Post-operative Hemorrhage
Evaluating Perioperative Dexamethasone and the Risk of Bleeding in Tonsillectomy
Tonsillectomy (removal of the tonsils) is a very common surgery in children. Bleeding after tonsillectomy is one of the risks of this surgery and can be more dangerous in children since they have less blood volume than adults.
- Trial name
- NCT01415583
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 314 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Tonsillectomy
Default Dosing Settings for Opioid Prescriptions to Adolescents and Young Adults After Tonsillectomy
This study will evaluate whether lowering the default number of doses for opioid prescriptions written in an electronic health record system can decrease opioid prescribing without causing unintended consequences such as worsened…
- Trial name
- NCT04066829
- Testing
- Default setting intervention
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- University of Michigan
Tonsillitis, Airway Obstruction
Acetaminophen's Efficacy For Post-operative Pain
The purpose of this study is to compare IV acetaminophen to oral acetaminophen for pain control in children undergoing tonsillectomy with or without adenoidectomy.
- Conditions
- Tonsillitis, Airway Obstruction, Difficulty Swallowing
- Trial name
- NCT01721486
- Testing
- IV acetaminophen, PO acetaminophen
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Kaveh Aslani, MD
Cheilitis, Angular, Postoperative Complications
Using Dexpanthenol Cream to Prevent Lip Corner Cracks in Children After Tonsil/Adenoid Surgery
Soreness and cracking at the corners of the mouth, a condition called angular cheilitis, can be an uncomfortable problem for children after they have surgery to remove their tonsils and adenoids.
- Conditions
- Cheilitis, Angular, Postoperative Complications, Adenotonsillar Hypertrophy
- Trial name
- PrevAC-PedAT (NCT07002632)
- Testing
- Dexpanthenol 5 % Topical Ointment
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Postoperative Pain, Postoperative Nausea and Vomiting
Effect of Steroids on Post-tonsillectomy Morbidities
This study aims to evaluate the effect of postoperative systemic rapid onset and short acting dexamethasone followed by a tapering dose of oral prednisolone on post-tonsillectomy morbidities.
- Trial name
- NCT02401529
- Testing
- IV dexamethasone, Oral prednisolone, Paracetamol
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Fahd General Hospital
Postoperative Pain, Acute Pain
Pharmacokinetic, Efficacy and Safety Study of Tapentadol Oral Solution in Children With Postoperative Pain
To find out if a drug called tapentadol administered by mouth safely relieves pain in children. Look at the amount of tapentadol in the blood after a single oral dose.
- Trial name
- NCT01729728
- Testing
- Tapentadol
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Grünenthal GmbH
Tonsillectomy
Celecoxib After Tonsillectomy
Tonsillectomy is one of the most common pediatric surgical procedures in the United States. Postoperative pain is substantial, with typical regimens employing narcotic derivatives and acetaminophen for 1-2 weeks after surgery.
- Trial name
- NCT02934191
- Testing
- Celecoxib, Acetaminophen, Oxycodone
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Children's Hospital of Philadelphia
Post-tonsillectomy Pain, Post-tonsillectomy Activity
The Effects of Reducing Stomach Acid on Post-tonsillectomy Pain
This study was designed to determine whether post-operative pain following a tonsillectomy can be reduced by adding an antacid-like medication to the medications taken after surgery.
- Conditions
- Post-tonsillectomy Pain, Post-tonsillectomy Activity, Post-tonsillectomy Hydration
- Trial name
- NCT00472186
- Testing
- Lansoprazole
- Where
- 2 sites in United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Tonsillectomy, Adenoidectomy
Postoperative Ibuprofen and the Risk of Bleeding After Tonsillectomy With or Without Adenoidectomy
Tonsillectomy (the surgical removal of the tonsils) is a commonly performed surgery in children. One risk of tonsillectomy is postoperative bleeding, and this can be more dangerous in children because their blood volume is lower…
- Trial name
- NCT01605903
- Testing
- Ibuprofen, Acetaminophen
- Where
- 5 sites in United States
- Volunteers
- 741 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Adenotonsillectomy, Post-operative Analgesia
Non-opioids for Analgesia After Adenotonsillectomy in Children
The goal of this study is to determine if non-opioid pain control is a safe way to manage pain after adenotonsillectomy surgery in children.
- Conditions
- Adenotonsillectomy, Post-operative Analgesia, Opioid Use
- Trial name
- NCT03618823
- Testing
- Oxycodone, Ibuprofen, Acetaminophen
- Where
- United States
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- David Chi, MD
Pain
Does Montelukast Decrease Post Adenotonsillectomy Pain in Children
Objective: The purpose of the present study is to evaluate the effectiveness of preoperative Montelukast as an analgesic for adenotonsillectomy Study Design: Randomized controlled double blinded clinical trial.
- Trial name
- Montelukast (NCT02793375)
- Testing
- Montelukast
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pediatric Adenotonsillectomy, Post Operative Analgesia
Dexmedetomidine in Pediatric Tonsillectomy
The hypothesis of this study is that the administration of an intra-operative dose of dexmedetomidine will result in adequate analgesia without respiratory depression thereby resulting in an early discharge from the post…
- Trial name
- NCT01057381
- Testing
- Dexmedetomidine 0.75 mcg/kg, Morphine 50 mcg/kg, Morphine 100 mcg/kg
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Sleep Apnea, Obstructive, Tonsillectomy
The Effect of Caffeine on Postextubation Adverse Respiratory Events in Children With Obstructive Sleep Apnea (OSA).
This is a research study using caffeine in children who have an obstructive sleep apnea (OSA). OSA means children who stop breathing during their sleep due to obstruction in their airway.
- Conditions
- Sleep Apnea, Obstructive, Tonsillectomy, Adenoidectomy, Postoperative Complications
- Trial name
- OSA (NCT00273754)
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- The University of Texas Health Science Center, Houston
Adenotonsillectomy, Analgesia
Post-operative Course of Dexamethasone to Reduce Tonsillectomy Morbidity
The goal of this study is determine if an oral systemic course of steroids is a safe and effective option in lowering pain and complications following adenotonsillectomy in various pediatric age groups.
- Conditions
- Adenotonsillectomy, Analgesia, Surgery
- Trial name
- NCT04879823
- Testing
- Dexamethasone, Ibuprofen, Acetaminophen
- Where
- 2 sites in United States
- Volunteers
- 222 people
- Sponsor
- David Chi, MD
Post Operative Pain Management in Children With Tonsillectomy/Adenoidectomy
Preoperative Gabapentin for Post-tonsillectomy Pain in Children
The typical post-operative course for children following surgical removal of their tonsils and adenoids can be challenging, especially for pain control.
- Trial name
- NCT01707420
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Colorado, Denver
Pain, Postoperative
Opioid & Steroid Use Following Tonsillectomy in Pediatric Patients
The purpose of this study is to determine if a post-operative course of oral dexamethasone affects opioid usage in pediatric patients undergoing tonsillectomy.
- Trial name
- NCT04541147
- Testing
- Dexamethasone, Analgesics
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Duke University
Adenotonsillectomy, Post-operative Analgesia
Non-Opioid Pain Medications After Intracapsular Adenotonsillectomy
The goal of this study is to determine if non-opioid pain control is a safe way to manage pain after intracapsular adenotonsillectomy surgery in children.
- Conditions
- Adenotonsillectomy, Post-operative Analgesia, Opioid Use
- Trial name
- NCT04791761
- Testing
- Oxycodone, Ibuprofen, Acetaminophen
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- David Chi, MD