Clinical trials: Post-Traumatic
Post-Traumatic Stress Disorder
Lending a Hand to Our Future: PTSD in Refugee Children and Youth
Immigrant and refugee children and youth are the fastest growing segment of Canadian society, but their mental health is too often overlooked even though their high rates of symptoms are increasingly of concern.
- Trial name
- LHOF (NCT02334566)
- Testing
- NET TX
- Volunteers
- 588 people
- Sponsor
- Unity Health Toronto
Post-Traumatic Stress Disorder
Assessing PTSD After Earthquake in Turkey
Assessing the prevalence and natural course of PTSD after the 1999 Turkish earthquake
- Trial name
- NCT00269451
- Sponsor
- Sheba Medical Center
Aortic Aneurysm, Thoracic, Descending Thoracic Aortic Dissection
Valiant Thoracic Stent Graft With the Captivia Delivery System in the Treatment of Descending Thoracic Aortic Diseases (VALIANT CAPTIVIA France)
The objective of this study is to assess the benefits of endovascular technique in terms of efficacy and safety of Valiant Thoracic Stent Graft with the Captivia Delivery System in the treatment of thoracic aortic disease, in a…
- Conditions
- Aortic Aneurysm, Thoracic, Descending Thoracic Aortic Dissection, Penetrating Ulcer, Aorta Thoracic; Traumatic Rupture
- Trial name
- NCT01775046
- Testing
- DTA patients (Valiant)
- Where
- 17 sites in France
- Volunteers
- 160 people
- Sponsor
- Medtronic Cardiovascular
PTSD - Post Traumatic Stress Disorder, PTSD-Related Functional Impairment in Children and Adolescents
Development of the PTSD-iMPACT to Measure PTSD-Related Functional Impairment in Children and Adolescents - A Validation Study in Switzerland and Germany
Population-based and clinical studies indicate that a substantial proportion of children and adolescents are exposed to one or more potentially traumatic events (PTEs) Approximately 16 % of those affected by childhood trauma go…
- Trial name
- PTSD-iMPACT (NCT07368166)
- Where
- 11 sites in Germany, Switzerland
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Psychiatric Diagnosis, Schizophrenia Disorders
The Key to Integrated Trauma Treatment in Psychosis Trial
Schizophrenia spectrum disorders (SSDs) have a significant trauma etiology: trauma has been reported in 65 - 80% in this patient group and have a negative impact on prognosis.
- Conditions
- Psychiatric Diagnosis, Schizophrenia Disorders, Psychological Trauma, Historical
- Trial name
- KIT (NCT06608706)
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR) for psychosis
- Where
- 11 sites in Norway
- Volunteers
- 187 people
- Sponsor
- Haukeland University Hospital
Grief
Adolescent Suicide Loss Survivors Grief Intervention Group
This study will provide evidence-based recommendations for designing interventions tailored to adolescents dealing with suicide loss.
- Trial name
- NCT07151092
- Testing
- Adolescent Grief Group
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Best Tissue Constituent for Plantar Surface
Functional Outcome of Free Muscle Flaps Versus Free Skin Flaps for Post-traumatic Foot Plantar Surface Reconstruction
the investigators are trying to detect what is the best tissue constituent suitable for reconstruction of large post traumatic sof tissue defects of foot plantar surface
- Trial name
- NCT03152812
- Testing
- plantar surface reconstruction by free flaps
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- alhussein Ahmed Mahmoud El-Dahshan
Trauma, Posttraumatic Stress Disorder
Increasing Treatment Access in Trauma Exposed Children: Developing an Adapted Step One Intervention (RCT)
One of the most common and widely disseminated trauma treatments is Trauma Focused Cognitive Behavioral Therapy (TF-CBT). TF-CBT is a therapist-led, structured and sequential intervention, with treatment organized around…
- Trial name
- NCT07396974
- Testing
- Personalized Stepped Care Cognitive Behavioral Therapy for Children after Trauma (pSC-CBT-CT), Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Vicarious Trauma, Psychological Distress
Efficacy of Vicarious Post-Traumatic Growth Intervention for Nurses in Emergency Units
This randomized controlled trial aims to evaluate the efficacy of a Vicarious Post-Traumatic Growth (VPTG) Intervention among nurses working in emergency units.
- Conditions
- Vicarious Trauma, Psychological Distress, Post-Traumatic Growth, Psychological, Psychological Well-being
- Trial name
- VPTG-RCT (NCT07677527)
- Testing
- Psychoeducational Vicarious Post-Traumatic Growth Intervention
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fatima Jinnah Women University
Post-Traumatic Stress Disorder
Brain Receptor Function in Post-Traumatic Stress Disorder
The purpose of this study is to examine the function of cortisol receptors in post-traumatic stress disorder (PTSD). Patients with PTSD have neurobiological dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis function.
- Trial name
- NCT00046553
- Testing
- RU-486 (Mifepristone)
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Post-traumatic Stress Disorder
Feasibility of an Intervention for Somatic Flashbacks in PTSD
This trial will explore the feasibility and acceptability of an intervention for Somatic flashbacks in Post-Traumatic Stress Disorder (PTSD). Imagery Rescripting (ImRs) will form a central part of the intervention.
- Trial name
- NCT05996913
- Testing
- Imagery rescripting
- Where
- 2 sites in United Kingdom
- Volunteers
- 15 people
- Sponsor
- University College, London
Female Genital Mutilation, Sexual Dysfunctions, Psychological
Sexual Health of Women With Genital Mutilation Seen at the Saint-Denis Women's Center
This study looks at the sexual health of women who have experienced female genital mutilation (FGM) and who are receiving care at the Women's Center at Saint-Denis Hospital.
- Conditions
- Female Genital Mutilation, Sexual Dysfunctions, Psychological, Sexual Health, Violence Against Women
- Trial name
- NCT07027696
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Risk Reduction Through Family Therapy, Usual Care
Risk Reduction for Drug Use and Sexual Revictimization
The investigator proposes to evaluate Risk Reduction through Family Therapy (RRFT), which integrates: 1) an ecologically-based intervention for treatment of substance abuse behaviors in high risk adolescents, 2) exposure-based…
- Trial name
- RRFT (NCT00998153)
- Testing
- Risk Reduction through Family Therapy
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Medical University of South Carolina
Depression, Post Traumatic Stress Disorder
The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Registry
While effective interventions for depression exist, their success rates are unsatisfactory and their provision is haphazard. The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Depression Hub will improve…
- Conditions
- Depression, Post Traumatic Stress Disorder, Bipolar Disorder, Mood Disorder
- Trial name
- NCT02443636
- Where
- Canada
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Trauma, Injury Traumatic
Trauma Follow-Up Prediction (Project 2: Aim 1)
Traumatic injury and inadequate follow-up care are a significant cause of morbidity and 10% of all deaths in sub-Saharan Africa (SSA).
- Conditions
- Trauma, Injury Traumatic, Injuries
- Trial name
- NCT05430165
- Testing
- Standard mHealth screening (triage) tool
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Mefire Alain Chichom
Degenerative Joint Disease of Knee, Osteoarthritis
A Randomized Controlled Trial for Partial Knee Arthroplasty
This is a prospective, multi-center, two-arm, randomized, controlled post-market study to evaluate and compare the clinical accuracy of component placement in robotic-assisted UKA and that of traditional methods.
- Conditions
- Degenerative Joint Disease of Knee, Osteoarthritis, Traumatic Arthritis, Varus Deformity
- Trial name
- NCT05037734
- Testing
- Persona Partial Knee System
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Osteoarthritis, Rheumatoid Arthritis
Minimally Invasive Versus Conventional Approaches in Navigated Total Knee Arthroplasty (TKA)
50 patients are randomized to two groups who receive a navigated knee prosthesis. Aim of the study is a comparison between a minimally invasive and a conventional approach.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis
- Trial name
- NCT00839020
- Testing
- Navigated TKA with a minimally invasive approach, Navigated TKA with a conventional approach
- Where
- Germany
- Volunteers
- 26 people
- Sponsor
- Aesculap AG
Brain Concussion, Post-Concussion Syndrome
Early Intervention Programme for Young Patients (Aged 15 - 30 Years) With Symptoms Following Concussion.
Background: Five - 15 % of patients with concussion continue to experience impairing physical, cognitive and emotional symptoms longer than 3 months post-injury.
- Trial name
- NCT02337101
- Testing
- Enhanced Usual Care (EUC), EUC + Early intervention programme
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- University of Aarhus
Intimate Partner Violence (IPV), Depression
Multi-component Family Intervention to Lower Depression and Address Intimate Partner Violence in Nepal
Intimate Partner Violence (IPV) is a major public health problem in low- and middle-income countries (LMICs). Globally, an estimated 30% of women report physical or sexual violence by an intimate partner in their lifetime.
- Conditions
- Intimate Partner Violence (IPV), Depression, PTSD - Post Traumatic Stress Disorder
- Trial name
- MILAP (NCT06834867)
- Testing
- MILAP intervention
- Where
- Nepal
- Volunteers
- 900 people
- Sponsor
- Possible
Posttraumatic Stress Disorder, Aggressive Behavior
Adressing PTSD Symptoms and Aggressive Behavior in Vulnerable Children in Burundi
Children either living in the streets of Bujumbara or that are similarly affected by extreme poverty or violence are regularly exposed to traumatic events.
- Trial name
- NCT03498482
- Testing
- Narrative Exposure Therapy for Forensic Offender Rehabilitation (FORNET)
- Where
- Burundi
- Volunteers
- 19 people
- Sponsor
- University of Konstanz