Clinical trials: Post-Traumatic
PTSD
Immunological Changes Through Narrative Treatment of Post-Traumatic Stress Disorder (PTSD) in Torture Victims
Posttraumatic stress disorder (PTSD) is associated with poor health, high health care utilization, and an increased risk for a variety of somatic, inflammatory and autoimmune diseases.
- Trial name
- NCT01206790
- Testing
- NET
- Where
- Germany
- Volunteers
- 47 people
- Sponsor
- University of Konstanz
PTSD, Depression
Online and Shared Decision-Making Interventions to Engage Service Men and Women in Post-Deployment Mental Health Care
OEF/OIF/OND war Veterans have unique post-deployment care needs that the VA is striving to understand and address. Unfortunately, there is a significant disparity in utilization of mental health (MH) care and VA access as most…
- Conditions
- PTSD, Depression, Substance Use Disorder, Traumatic Brain Injury
- Trial name
- eSDM (NCT03539068)
- Testing
- WEB-ED+ Treatment Arm
- Where
- United States
- Volunteers
- 1,312 people
- Sponsor
- VA Office of Research and Development
Orbital Fractures
Intra-operative (IO) Navigation and IO-CBCT for 3D Orbital Reconstruction
Background Correction of post traumatic and post-ablative orbita defects remains a challenge for the maxillofacial surgeon. The purpose of such intervention is the restoration of both function and aesthetics by anatomical…
- Trial name
- NCT03057405
- Volunteers
- 22 people
- Sponsor
- AZ Sint-Jan AV
Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis
Gait Rehabilitation to Treat FastOA
The purpose of this study is to determine the effects of real-time gait biofeedback delivered over a 6-week period on early markers of FastOA and conduct 6-week and 6-month follow-up assessments in anterior cruciate ligament…
- Conditions
- Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Knee Osteoarthritis, Osteo Arthritis Knee
- Trial name
- NCT05848622
- Testing
- Real-time gait biofeedback
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of North Carolina, Chapel Hill
Traumatic Brain Injury, Brain Concussion
Vestibular Rehabilitation and Balance Training After Traumatic Brain Injury
The main aim of this study is to evaluate the effect of vestibular rehabilitation and balance training on patients with dizziness and balance problems after traumatic brain injury.
- Conditions
- Traumatic Brain Injury, Brain Concussion, Head Injury, Dizziness
- Trial name
- VRTBI2012 (NCT01695577)
- Testing
- Multidisciplinary evaluation and VR, Multidisciplinary evaluation
- Where
- Norway
- Volunteers
- 65 people
- Sponsor
- Oslo University Hospital
Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis
PRP in ACLR to Prevent PTOA
The purpose of our study is to examine the effect of platelet-rich-plasma (PRP) injection on the short-term resolution of post-injury inflammation (biomarkers) and improvement in joint function in patients with acute ACL injury.
- Conditions
- Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, PRP
- Trial name
- NCT05412381
- Testing
- platelet rich plasma (PRP) injection
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Hospital for Special Surgery, New York
Mental Health, Physical Health
Parental Well-being After Childbirth in Switzerland
Improving maternal and child health is a global priority, with increasing emphasis on ensuring women and their families not only survive but also thrive after childbirth.
- Conditions
- Mental Health, Physical Health, Postpartum, Parents
- Trial name
- SOCRATES (NCT06886841)
- Where
- 2 sites in Switzerland
- Volunteers
- 4,200 people
- Sponsor
- Laurent Gaucher
Borderline Personality Disorder
NEUROIMAGING OF ADOLESCENT BORDERLINE PERSONALITY DISORDER WITH AND WITHOUT POST-TRAUMATIC STRESS DISORDER
Borderline personality disorder (BPD) is a common mental disorder in adolescents with significant individual and societal repercussions, characterized over the long term by emotional hyperresponsiveness, relational instability…
- Trial name
- BorderStress (NCT04852744)
- Testing
- Brain MRI
- Where
- France
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Post Traumatic Stress Disorder
Sleep and Emotion Processing in Adolescent Post-traumatic Stress Disorder
The goal of this clinical trial is to characterize the role of sleep, emotion processing, and daily affect in post-traumatic stress disorder (PTSD) and whether improving sleep quality using slow wave activity enhancement will…
- Trial name
- NCT06341413
- Testing
- SmartSleep device
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Post-Traumatic Stress Disorder
Role of Substance P in Post-Traumatic Stress Disorder
This study will examine the role of substance P, a chemical messenger in the brain, in post-traumatic stress disorder (PTSD), a chronic anxiety disorder.
- Trial name
- NCT00102102
- Testing
- [18F]SPA-RQ
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Traumatic Cataract
Long-term Visual and Refractive Outcomes After Traumatic Cataract Surgery in Children
This prospective multicenter observational study aims to evaluate long-term visual and ocular biometric outcomes in pediatric patients aged 0-16 years who were diagnosed with traumatic cataract and underwent cataract extraction…
- Trial name
- NCT07087275
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Jin Yang
PTSD
IPT-A for Adolescents With PTSD Symptoms
In the present study, the investigators propose to 1) adapt Interpersonal Psychotherapy for Adolescents (IPT-A) as an intervention for adolescents who report elevated symptoms of posttraumatic stress disorder (PTSD) and/or meet…
- Trial name
- NCT03795818
- Testing
- Interpersonal Psychotherapy for Adolescents
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- New York State Psychiatric Institute
Mild Traumatic Brain Injury, Headaches Posttraumatic
SMART Concussion Trial: Symptom Management vs Alternative Randomized Treatment of Concussion Trial
Given the rising rates of concussion in youth ages 10-19 and the significant proportion of young people who remain symptomatic for months following concussion, research evaluating the efficacy of multifaceted treatment options…
- Conditions
- Mild Traumatic Brain Injury, Headaches Posttraumatic, Neck Pain, Dizziness
- Trial name
- SMART (NCT05446597)
- Testing
- Symptom-specific Headache Treatment, Symptom-specific Dizziness &/or Neck Pain Treatment, Multimodal Concussion Treatment
- Where
- Canada
- Volunteers
- 62 people
- Sponsor
- University of Calgary
Posttraumatic Growth, Posttraumatic Stress Disorder
Stress, Adjustment And Growth In Children With Cancer And Their Parents
This proposal examines trauma and growth responses in the childhood cancer experience. It addresses a number of gaps and unanswered questions in the literature, while integrating several distinct but related lines of research.
- Trial name
- NCT01044160
- Where
- United States
- Volunteers
- 663 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Concussion, Mild
Mindfulness-Based Intervention for Mild Traumatic Brain Injury
Mindfulness is a promising tool which may foster adaptative interpersonal qualities to reduce the risk of persistent post-concussion symptoms.
- Trial name
- MBI-4-mTBI (NCT05105802)
- Testing
- Mindfulness-Based Intervention
- Where
- Canada
- Volunteers
- 99 people
- Sponsor
- Children's Hospital of Eastern Ontario
Post Traumatic Skin Loss
Negative Pressure Wound Therapy in Traumatic Skin Loss
Assessment of the effectiveness of negative pressure wound therapy on post-traumatic wounds, as regard to : The period of granulation tissue formation. The infection rate in NPWT in comparison to conventional dressing.
- Trial name
- NCT05653297
- Testing
- Vacuum-Assisted Closure
- Volunteers
- 50 people
- Sponsor
- Assiut University
Opioid Use, Traumatic Injury
Opioid Use After Traumatic Injury in Adolescents
Currently, 1 in 8 adolescents continue to receive prescription opioids a year or more after injury. By longitudinally surveying patients, we can identify risk factors and pathways to nonmedical opioid use.
- Conditions
- Opioid Use, Traumatic Injury, Adolescent Behavior, Substance Abuse Disorder
- Trial name
- NCT03628846
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Indiana University
HIV Prevention, PTSD and Substance Use Disorder
Preventing HIV Among Native Americans Through the Treatment PTSD & Substance Use
Investigators will conduct a two-arm, comparative effectiveness randomized controlled trial of two culturally adapted, empirically based programs (EBP) - Narrative Exposure Therapy (NET) vs.
- Trial name
- NCT03112369
- Testing
- Narrative Exposure Therapy (NET), Motivational Interviewing w/Skills Training (MIST)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Washington
Post-Traumatic Stress Disorder in Children
Validation of the Turkish Version of PTSD-RI-5
The aim of this study is to investigate the adaptation and validity of the DSM-5 PTSD-RI -5 scale in patients who have been exposed to traumatic events.
- Trial name
- NCT06077474
- Testing
- Testing the the DSM-5 UCLA Posttraumatic Stress Disorder Reaction Index Self-Report Scale for Children and Adolescents (PTSD-RI-5)
- Where
- Turkey (Türkiye)
- Volunteers
- 157 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Drug Use, Drug Abuse
Prevention of Post Sexual Assault Stress
The purpose of this study is to evaluate whether a brief intervention in video format, that includes education about reactions to assault and modeling of adaptive coping strategies, designed to reduce post assault drug use or…
- Conditions
- Drug Use, Drug Abuse, Posttraumatic Stress Disorder
- Trial name
- NCT01430624
- Testing
- PPRS, PIRI
- Where
- 2 sites in United States
- Volunteers
- 245 people
- Sponsor
- Medical University of South Carolina