Clinical trials: Post-Traumatic Stress Disorder
Trauma, Posttraumatic Stress Disorder
Increasing Treatment Access in Trauma Exposed Children: Developing an Adapted Step One Intervention (Pilot)
One of the most common and widely disseminated trauma treatments is Trauma Focused Cognitive Behavioral Therapy (TF-CBT). TF-CBT is a therapist-led, structured and sequential intervention, with treatment organized around…
- Trial name
- NCT07396935
- Testing
- Personalized Stepped Care Cognitive Behavioral Therapy for Children after Trauma (pSC-CBT-CT)
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Stress Disorders, Traumatic, Psychological Trauma
Effect Study of SMART Treatment for Youth
The goal of this clinical trial is to learn if Sensory motor arousal regulation treatment (SMART) works better than treatment as usual (TAU) to treat youth 7-17 years with complex trauma histories and self-regulation…
- Conditions
- Stress Disorders, Traumatic, Psychological Trauma, Sexual Trauma, Stress Disorders, Post-Traumatic; Mental Disorders
- Trial name
- UTVID (NCT07200713)
- Testing
- Treatment as usual (TAU), Sensory motor arousal regulation treatment (SMART)
- Where
- 4 sites in Norway
- Volunteers
- 120 people
- Sponsor
- Vestre Viken Hospital Trust
Depression, Anxiety
Efficacy of a Multi-level School Intervention for LGBTQ Youth
Efficacy of a Multi-level School Intervention for LGBTQ Youth
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder, Coping Behavior
- Trial name
- NCT05541406
- Testing
- Proud & Empowered, Control Group
- Where
- 23 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Acute Traumatic Stress Disorders, Post-Traumatic Stress Disorders
Evaluation of Stress Disorders
The purpose of this study is to examine the short-term consequences of trauma and to determine the effectiveness of the drug sertraline in preventing and treating post-traumatic stress disorder (PTSD) and acute stress disorder…
- Trial name
- NCT00050804
- Testing
- sertraline
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Acquired Immunodeficiency Syndrome, Stress Disorders, Post-Traumatic
HIV Prevention and Care of Psychological Trauma in Vulnerable Rwandan Youth
The investigators propose a prospective single arm pilot cohort study of 100 youth (ages 15-25) to evaluate the feasibility of this project.
- Trial name
- NCT01401335
- Testing
- Questionnaires
- Where
- 2 sites in United States, Rwanda
- Volunteers
- 120 people
- Sponsor
- Stanford University
Chronic Pain, Chronic Pain Syndrome
Outcomes Mandate National Integration With Cannabis as Medicine
This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury, Chronic Pain Due to Trauma
- Trial name
- OMNI-Can (NCT03944447)
- Testing
- Cannabis, Medical, RYAH-Medtech Inhaler
- Where
- 17 sites in United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- OMNI Medical Services, LLC
Intrusive Memories of Trauma, Symptom of Post Traumatic Stress Disorder (Criterion B1)
A Brief Cognitive Intervention After Intrusive Memories of Trauma With Young Refugees
This research study is designed to investigate the use of a simple cognitive task (a memory cue and 10 minute time gap, followed by playing the computer game "Tetris") for decreasing the number of intrusive memories of trauma…
- Trial name
- NCT03525158
- Testing
- Brief cognitive intervention
- Where
- 2 sites in Sweden
- Volunteers
- 4 people
- Sponsor
- Karolinska Institutet
Psychological Stress, Psychosocial Impairment
Evaluation of the Psychosocial Impact on Health Professionals Exposed During COVID 19 Coronavirus Pandemic
Application of a survey in electronic support to hospital professionals. This survey will include different demographics as well as questions from own elaboration about the different aspects related to the development of work…
- Conditions
- Psychological Stress, Psychosocial Impairment, Anxiety, Depression
- Trial name
- NCT04752839
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Post-Traumatic Stress Disorder in Adolescence, Post Traumatic Stress Disorder
Adaptation of the PCIP for Spanish Speaking Adolescents and Families
This study will implement a brief Post-traumatic Stress Disorder (PTSD) intervention for children, the Primary Care Intervention for PTSD (PCIP) delivered through telehealth (computer or smart phone delivery), to 10 Spanish…
- Trial name
- NCT05899322
- Testing
- Primary Care Intervention for PTSD Spanish Speaking Adolescents, Waitlist Treatment as Usual
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Stress Disorders, Post-Traumatic
Treatment of Post-Traumatic Stress Disorder (PTSD) in Sexually Abused Children
The purpose of this study is to compare the effectiveness of two psychological therapies used to treat PTSD in children who have recently been sexually abused: Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) vs Child…
- Trial name
- NCT00000383
- Testing
- Trauma-Focused CBT, Child-Centered Therapy
- Where
- 3 sites in United States
- Volunteers
- 229 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Posttraumatic Stress Disorder, PTSD
D-cycloserine Adjunctive Treatment for Posttraumatic Stress Disorder (PTSD) in Adolescents
The purpose of this study is to show whether D-cycloserine in combination with cognitive behavioral therapy (CBT) is more effective than CBT plus placebo to reduce symptoms of posttraumatic stress disorder (PTSD) in 13-18…
- Trial name
- NCT01157429
- Testing
- D-cycloserine, CBT
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Tulane University School of Medicine
Post-traumatic Stress Disorder
Effectiveness of a Brief Intensive Trauma Treatment for Adolescents With (s)PTSD: a Multi-center RCT
The primary objective of this study is to examine the effectiveness of a Brief Intensive Trauma Treatment (BITT) for adolescents with (s)PTSD.
- Trial name
- NCT06143982
- Testing
- Brief Intensive Trauma Treatment
- Where
- 3 sites in Bonaire, Saint Eustatius and Saba , Netherlands
- Volunteers
- 100 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Childhood Traumatic Grief, Post Traumatic Stress
Randomized Controlled Trial of Trauma-focused CBT in Tanzania and Kenya
The primary goal is to study the effectiveness of Trauma-focused Cognitive Behavioral Therapy (TF-CBT) in treating traumatic grief and traumatic stress for orphaned children and young adolescents in two East African sites with…
- Conditions
- Childhood Traumatic Grief, Post Traumatic Stress, Post Traumatic Stress Disorder, Depressive Symptoms
- Trial name
- NCT01822366
- Testing
- Trauma-focused Cognitive Behavioral Therapy
- Where
- 3 sites in United States, Kenya and 1 more
- Volunteers
- 1,280 people
- Sponsor
- Duke University
Borderline Personality Disorder, Posttraumatic Stress Disorder
CPT Group for DBT Clients With Co-Occurring Borderline Personality Disorder and PTSD
Even though borderline personality disorder (BPD) and posttraumatic stress disorder (PTSD) commonly co-occur, few studies have examined PTSD treatment among individuals with BPD.
- Trial name
- CPTDBT (NCT02574429)
- Testing
- Cognitive Processing Therapy
- Where
- 2 sites in Canada
- Volunteers
- 45 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Post Traumatic Stress Disorder, Technology
Improving Quality of Care in Child Mental Health Service Settings
The investigators recently completed an NIMH R34 in which they piloted a patient- and provider-informed tablet-based toolkit designed to facilitate delivery of Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) - a treatment…
- Conditions
- Post Traumatic Stress Disorder, Technology, Child Abuse
- Trial name
- NCT03305458
- Testing
- TFCBT, eTFCBT
- Where
- United States
- Volunteers
- 713 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Posttraumatic Stress Disorder
Stepped Care for Young Children After Trauma
The aim of this R34 study is to develop and test the feasibility of a Stepped Care intervention for young children with Posttraumatic Stress Disorder (PTSD).
- Trial name
- NCT01603563
- Testing
- Stepped Care TF-CBT, Standard TF-CBT
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of South Florida
Anxiety, Depression
A Mobile Health Solution for Homework During CBT
The purpose of this study is to preliminarily evaluate a web-based app to improve provider implementation and patient engagement in homework (i.e., between-session practice of skills learned during therapy) during child mental…
- Conditions
- Anxiety, Depression, Posttraumatic Stress Disorder
- Trial name
- NCT04931199
- Testing
- Cognitive Behavioral Therapy (CBT), CBT+App
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of South Florida
PTSD, Adolescent
Neural Connectivity During Therapy for Adolescent PTSD
Posttraumatic stress disorder in adolescence impairs neurobiological networks underlying cognitive, social and emotional skills.
- Conditions
- PTSD, Adolescent, Psychological Trauma
- Trial name
- NCT05423444
- Testing
- TF-CBT, TAU
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
CPTSD, Compelx Post-traumatic Stress Disorder
The Effectiveness of Guided Written Exposure Therapy for Complex PTSD in Adolescents
This study aims to examine the effectiveness of group Guided Written Exposure Therapy for Complex Post-Traumatic Stress Disorder (GWE-C) among Chinese adolescents through a randomized controlled trial.
- Trial name
- NCT07325734
- Testing
- Group Guided Written Exposure Therapy for CPTSD (GWE-C), Supportive Group
- Where
- 4 sites in China
- Volunteers
- 130 people
- Sponsor
- Peking University
Anxiety Disorders, Panic Disorder
Initial Severity and Antidepressant Efficacy for Anxiety Disorders: an Individual Patient Data Meta-analysis
Anxiety disorders are common disorders, which pose a major burden to society and the individual. An anxiety disorder may be treated with medication, in particular with antidepressants such as the selective serotonin reuptake…
- Conditions
- Anxiety Disorders, Panic Disorder, Obsessive-compulsive Disorder, Post-traumatic Stress Disorder
- Trial name
- NCT02476136
- Testing
- paroxetine, duloxetine, fluoxetine or venlafaxine
- Volunteers
- 8,800 people
- Sponsor
- prof. Peter de Jonge