Clinical trials: Post-Traumatic Stress Disorders
Post-traumatic Stress Disorder (PTSD), Current Significant Sleep Disturbances
Sleep Disturbances in Children and Adolescents With Post-traumatic Stress Disorder (PTSD): a Randomized Double-blind Placebo-controlled Trial to Investigate the Efficacy of Pediatric Prolonged-release Melatonin
Among the most sensitive and persistent symptoms of post-traumatic stress disorder (PTSD) in children are sleep disturbances in the insomnia spectrum (sleep onset disturbances, fragmented sleep with multiple nocturnal awakening…
- Trial name
- MelatoSomKids (NCT07418554)
- Testing
- pediatric, prolonged released melatonin
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Strasbourg, France
Post Traumatic Stress Disorder
Short-term Intervention and Health Trajectories After Mass Trauma
This study has two aims. The first is to understand more of what may be typical health trajectories after mass trauma for children and adults and what predicts these trajectories.
- Trial name
- NCT05042323
- Testing
- TF-CBT-Short
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Stress, Trauma
Exploring PTSD Symptoms, Barriers and Facilitators to Mindfulness
The purpose of this study is to investigate justice-involved Black/African American female adolescents' (JI BAFAs; N=35) self-reported outcomes: stress, posttraumatic stress disorder (PTSD), recidivism, etc., as well as their…
- Conditions
- Stress, Trauma, PTSD, HPA
- Trial name
- NCT06311188
- Testing
- ITR Healing intervention
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Emotions, Memory Deficits
Brain Response to Treatment for Pediatric PTSD
This study will examine how brain activation changes as a result of behavioral treatment for posttraumatic stress disorder (PTSD) in adolescents.
- Conditions
- Emotions, Memory Deficits, Post-traumatic Syndrome
- Trial name
- NCT01806701
- Testing
- Trauma-focused cognitive behavioral therapy
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Stanford University
Stress Disorders, Traumatic, Acute
Propranolol for the Treatment of Acute Stress Disorder
This 10-week study will examine whether propranolol, a medication that blocks the activity of the stress hormones adrenaline and noradrenaline, can relieve acute stress disorder (ASD) and symptoms from persisting long-term.
- Trial name
- NCT00069355
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Mental Health (NIMH)
Psychological Trauma, Depression
PCORI-1306-02918 Evaluation of Parent-based Programs to Support Children After Traumatic Injury
Children presenting to the University of Iowa Health Care System (UIHC), Blank Children's Hospital (Blank), Children's Hospital of Minneapolis, and Kansas City Mercy Children's Hospital with an injury resulting in admission will…
- Conditions
- Psychological Trauma, Depression, Coping
- Trial name
- NCT02323204
- Testing
- Link for Injured Kids, So you've been in an accident
- Where
- 4 sites in United States
- Volunteers
- 628 people
- Sponsor
- Marizen Ramirez
Posttraumatic Stress Disorder
Mind-Body Skills Groups for the Treatment of War-Related Trauma in Children in Gaza
The objective of this study is to determine whether participation in a mind-body skills program by war-traumatized children in Gaza will result in improvement of posttraumatic stress symptoms, depression, and decreased…
- Trial name
- NCT01595477
- Testing
- Mind-Body Skills Group
- Where
- Israel
- Volunteers
- 114 people
- Sponsor
- The Center for Mind-Body Medicine
CPTSD, Compelx Post-traumatic Stress Disorder
The Effectiveness of Guided Written Exposure Therapy for Complex PTSD in Adolescents
This study aims to examine the effectiveness of group Guided Written Exposure Therapy for Complex Post-Traumatic Stress Disorder (GWE-C) among Chinese adolescents through a randomized controlled trial.
- Trial name
- NCT07325734
- Testing
- Group Guided Written Exposure Therapy for CPTSD (GWE-C), Supportive Group
- Where
- 4 sites in China
- Volunteers
- 130 people
- Sponsor
- Peking University
Substance Use Disorders, Post-Traumatic Stress Disorder
Evaluating the Integration of Indigenous Healing With Principals of Seeking Safety for Treatment of Indigenous Patients With a History of Trauma and Active Substance Use Disorder.
Background: The negative health outcomes experienced by Indigenous peoples may be understood as direct consequences of colonization.
- Conditions
- Substance Use Disorders, Post-Traumatic Stress Disorder, Intergenerational Trauma
- Trial name
- NCT04604574
- Testing
- Indigenous Healing and Seeking Safety
- Where
- Canada
- Volunteers
- 550 people
- Sponsor
- Health Sciences North Research Institute
Anxiety, Stress Disorder, Posttraumatic
BLOOM: Boldly Living outdOOrs for Mental Health
In 2019, the Office of the California Surgeon General launched the ACEs Aware Initiative in collaboration with the California Department of Health Care Services.
- Conditions
- Anxiety, Stress Disorder, Posttraumatic, Loneliness, Adverse Childhood Experiences
- Trial name
- BLOOM (NCT05973123)
- Testing
- Group Nature Outings, Family Outings
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Stress Disorders, Post-Traumatic
Brain Structure and Function Before and After Treatment for Post-Traumatic Stress Disorder
This study, conducted at the University of Pennsylvania and at the National Institutes of Health in Bethesda, Maryland, will examine deficits in brain structure and function in people exposed to trauma who developed…
- Trial name
- NCT00069225
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
ADHD, PTSD
Trauma-adapted Yoga in Child & Adolescent Psychiatry.
The goal of this randomized clinical trial is to evaluate the efficacy of trauma-adapted yoga as a complementary intervention to care as usual in child and adolescents psychiatry clinics, in the population of adolescents with the…
- Conditions
- ADHD, PTSD, Quality of Life, Self-Control
- Trial name
- TAY-CAP (NCT06330779)
- Testing
- Trauma-adapted yoga
- Where
- Sweden
- Volunteers
- 180 people
- Sponsor
- University West, Sweden
Posttraumatic Stress Disorders
Ifenprodil Tartrate Treatment of Adolescents With Post-traumatic Stress Disorder: a Double-blind, Placebo-controlled Trial
Accumulating evidence suggests a key role of the N-methyl-D-aspartate (NMDA) receptor in the pathophysiology of post-traumatic stress disorder (PTSD).
- Trial name
- NCT01896388
- Testing
- Ifenprodil Tartrate
- Where
- Japan
- Volunteers
- 10 people
- Sponsor
- Chiba University
Post-traumatic Stress Disorder, Depression
Randomized Control Trial of Group Intervention With Former War-affected Boys in the Democratic Republic of Congo
The purpose of this study is to evaluate, in a randomised control trial (RCT), the effectiveness of group-based, trauma-focused Cognitive Behaviour Therapy (TF-CBT) in reducing psychological distress in former child soldiers and…
- Conditions
- Post-traumatic Stress Disorder, Depression, Conduct Disorder
- Trial name
- NCT01494831
- Testing
- TF-CBT
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Post Traumatic Stress Disorder (PTSD), Depressive Symptoms
The Norwegian Stepped-Care TF-CBT Study
Every day, a significant number of children and young people in Norway experience violence, abuse, or other potentially traumatizing events.
- Conditions
- Post Traumatic Stress Disorder (PTSD), Depressive Symptoms, Parental Stress, Health Related Quality of Life
- Trial name
- NCT04073862
- Testing
- Stepped-Care TF-CBT
- Where
- Norway
- Volunteers
- 82 people
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Traumatic Injury, Technology
Evaluation of Trauma Center-Based Intervention for Adolescent Traumatic Injury Survivors
Pediatric traumatic injury (i.e., injury of sudden onset and severity requiring immediate attention) is the leading cause of death and morbidity among US adolescents and are associated with mental health and health risk outcomes…
- Conditions
- Traumatic Injury, Technology, Posttraumatic Stress Disorder, Adolescents
- Trial name
- NCT05086757
- Testing
- TRRP, Enhanced Usual Care
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Severe Trauma, General Anaesthesia
Association Between a Peri-traumatic Dissociation State and the Occurrence of Post-traumatic Stress Syndrome
Patients will be selected after studying clinical records.Patients who had general anesthesia due to an injury related to severe trauma within 6 to 12 months prior to inclusion will be included.
- Trial name
- DIStress-AG (NCT03930966)
- Testing
- PDEQ, PCL-5 and demographic survey
- Where
- France
- Volunteers
- 148 people
- Sponsor
- University Hospital, Brest
Human Papilloma Virus
A Cohort Study of Hyperthermia and Imiquimod for the Treatment of Flat Warts
flat warts are a superficial viral skin disease, extremely common in childhood.Treatment of warts is often difficult and involves different destructive procedures.Although several pharmacological and physical topical treatments…
- Trial name
- NCT05146895
- Testing
- Imiquimod treatment, Local Hyperthermia at 44℃
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- First Hospital of China Medical University
Trauma
Psycho-education Program BLAME-LESS and It's Effect on Traumarelated Shame and Guilt
The primary objective of the BLAME-LESS study is to examine the effectiveness of an online psychoeducation program in reducing trauma-related feelings of shame and guilt in adolescents who experienced sexual or physical abuse .
- Trial name
- BLAME-LESS (NCT05987735)
- Testing
- BLAME-LESS
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- Karakter Kinder- en Jeugdpsychiatrie
Perinatal Depression
Perinatal Mental Health for Refugee Women
Since February 24th, 2022, the beginning of Russia's aggression against Ukraine, more than 80,000 women were expected to give birth.
- Trial name
- PMH-RW (NCT05654987)
- Where
- 2 sites in Poland, Ukraine
- Volunteers
- 600 people
- Sponsor
- Universidad Nacional de Educación a Distancia