Clinical trials: Post-operative
Anastomotic Leakage
Anastomotic Leakage Following Laparoscopic Resection for Rectal Cancer
Anastomotic leak (AL) is a breakdown of a suture line in a surgical anastomosis with a subsequent leakage of the luminal content.
- Trial name
- NCT02718729
- Testing
- Laparoscopic resection for rectal cancer
- Where
- 2 sites in Egypt, Italy
- Volunteers
- 59 people
- Sponsor
- Mansoura University
Pain, Postoperative
Exploring the Effects of Transcutaneous Electrical Acupoint Stimulation Therapy on Patients After Video-Assisted Thoracoscopic Surgery
Thoracic surgery is known to be one of the most painful types of surgery. If acute postoperative pain is not properly managed, there is a high risk that it may develop into clinically significant chronic pain within six months…
- Trial name
- NCT07287657
- Testing
- Standard Analgesia, Transcutaneous Electrical Nerve Stimulation (TENS), Transcutaneous Electrical Acupoint Stimulation (TEAS)
- Where
- Taiwan
- Volunteers
- 96 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Gastric and Esophagogastric Junction Adenocarcinoma
Postoperative Immunotherapy vs Standard Chemotherapy for Gastric Cancer With High Risk for Recurrence
The primary objective of the trial is to investigate if nivolumab plus ipilimumab given as adjuvant treatment improve disease free survival (DFS) in patients with stage Ib-IVa gastric and esophagogastric junction adenocarcinoma…
- Trial name
- VESTIGE (NCT03443856)
- Testing
- Nivolumab and Ipilimumab, chemotherapy
- Where
- 28 sites in Czechia, France and 7 more
- Volunteers
- 197 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Rectal Cancer, Rectal Adenocarcinoma
Factors Predicting Recurrence in Rectal Cancer After Surgery
Colorectal cancer is one of the most frequently diagnosed cancers and a major cause of cancer deaths worldwide. Recurrence after curative surgery is one of the major factors affecting the long-term survival and its frequency is…
- Trial name
- NCT03899870
- Testing
- Rectal resection, Neoadjuvant therapy, Adjuvant therapy
- Volunteers
- 188 people
- Sponsor
- ammar houssem
Adenotonsillar Hypertrophy, Postoperative Pain
Conox-Guided Anesthesia in Pediatric Adenotonsillectomy
This study aims to evaluate the effect of Conox (qCON/qNOX)-guided anesthesia on intraoperative anesthetic drug consumption and postoperative outcomes in pediatric patients undergoing adenotonsillectomy.
- Trial name
- NCT07577154
- Testing
- Conox Monitor, Standard Anesthesia Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Kayseri City Hospital
Ureteropelvic Junction Obstruction, Hypospadias
Effect of Oxybutynin on Opioid Use After Urologic Surgery in Children
The goal of this clinical trial is to determine whether giving oxybutynin before urologic reconstruction surgery reduces the amount of opioid pain medication needed in children.
- Trial name
- NCT07911137
- Testing
- Oxybutynin
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Calgary
Crohn Disease
Prediction and Close Monitoring of Postoperative Recurrence by Intestinal Ultrasound After Ileocecal Resection in Crohn's Disease Patients
Crohn's disease (CD) is an inflammatory bowel disease causing chronic transmural inflammation followed by intestinal complications including strictures and penetrating lesions such as fistulas and abscesses.
- Trial name
- INSIGHT (NCT05713409)
- Testing
- Intestinal ultrasound
- Where
- 5 sites in Germany, Italy and 2 more
- Volunteers
- 120 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Pain, Postoperative
Safety and Efficacy of Intranasal Ketamine for the Treatment of Postoperative Dental Pain
Once patients' postoperative pain intensity reaches a moderate-to-severe level, they are randomized to receive intranasal ketamine or placebo.
- Trial name
- NCT00488787
- Testing
- intranasal ketamine
- Volunteers
- 40 people
- Sponsor
- Javelin Pharmaceuticals
Postoperative Pain
Perioperative Use of Gabapentin To Decrease Narcotic Requirements in Spinal Fusion
Blinded study using oral gabapentin in load pre-operative (15mg/kg) and maintenance 5mg/kg three times a day (TID) for 5 days or discharge, Patient Controlled Analgesia (PCA) morphine and placebo group with similar pills, also…
- Trial name
- NCT00726999
- Testing
- Gabapentin, Morphine
- Volunteers
- 63 people
- Sponsor
- Medical College of Wisconsin
Malignant Hyperthermia
A Case Control Study of Patients With Diagnosis of Malignant Hyperthermia
The purpose of the study is to develop methods to identify predictors of Malignant Hyperthermia.
- Trial name
- NCT02561598
- Where
- United States
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Lung Adenocarcinoma, Surgical Procedure, Unspecified
Intraoperative Frozen Section Pathology to Diagnose the IASLC Grades for Lung Adenocarcinoma (ECTOP-1014)
This study is one of Eastern Cooperative Thoracic Oncology Projects (ECTOP-1014). The goal of this clinical trial is to confirm the concordance rate between intra-operative frozen section pathological diagnosis and post-operative…
- Conditions
- Lung Adenocarcinoma, Surgical Procedure, Unspecified, Pathology
- Trial name
- NCT05794698
- Testing
- Surgical resection
- Where
- China
- Volunteers
- 827 people
- Sponsor
- Fudan University
Patients With Traumatic Pain, Post-surgical Pain and Tooth Extract Pain
Celecoxib Japan Observational Study for the Patients With Acute Pain
This study is to assess the safety and efficacy of celecoxib on the pain relief from acute pain.
- Trial name
- NCT01876121
- Testing
- Celecoxib
- Where
- 7 sites in Japan
- Volunteers
- 784 people
- Sponsor
- Astellas Pharma Inc
Endocrine Procedural Complications, Thyroid
Intraoperative Monitoring to Predict Postoperative Complications After Thyroidectomy
The goal of this study is to evaluate the role of intraoperative continous and intermittent neuromonitoring and intraoperative parathormone (PTH) to predict postoperative nerve morbidity and hypocalcemia.
- Conditions
- Endocrine Procedural Complications, Thyroid, Parathyroid; Deficiency, Laryngeal Injury
- Trial name
- PARACAL (NCT03309384)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Central Hospital, Nancy, France
Laparoscopic Renal Surgery, Pain Management
TQLB for Postoperative Pain After Laparoscopic Partial Nephrectomy
This prospective, randomized study,control study aims to compare the analgesic effect,opioids consumption,quality of recovery,length of hospital stay，et al.
- Conditions
- Laparoscopic Renal Surgery, Pain Management, Nerve Block
- Trial name
- NCT03982784
- Testing
- single-injection TQLB(transmuscular quadratus lumborum block), Morphine given as IPCA(intravenous patient controlled analgesia)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Cui Xulei
Postoperative Nausea and Vomiting
Aprepitant PO vs Ondansetron IV for Prevention of Postoperative Nausea and Vomiting
Postoperative nausea and vomiting (PONV) persists as one of the more common complications of surgery. Although rarely life-threatening, it is the postoperative outcome that is most unfavorable to patients, even more undesirable…
- Trial name
- NCT00699894
- Testing
- aprepitant 40 mg, ondansetron 4 mg
- Where
- United States
- Sponsor
- Northwell Health
Postoperative Pain, Opioid Consumption
Comparison of TAP Block and Umbilical Paramedian Linea Semilunaris Block in Pediatric Laparoscopic Surgery
The aim of this prospective randomized controlled trial is to compare the postoperative analgesic efficacy of ultrasound-guided transversus abdominis plane (TAP) block and umbilical paramedian linea semilunaris block in pediatric…
- Trial name
- NCT07801794
- Testing
- Ultrasound-Guided Transversus Abdominis Plane Block, Ultrasound-Guided Linea Semilunaris Block
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Tracheal Stenosis
Investigation of the Effect of Systemic Steroids on Treatment and Prevention of Recurrent Tracheal Stenosis in Postoperative Patients
tracheal stenosis is the result of abnormal wound-healing processes leading to hypertrophic scar formation and obstruction of the airway lumen by excess granulation tissue.
- Trial name
- NCT02855502
- Testing
- Prednisolone
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- National Research Institute of Tuberculosis and Lung Disease, Iran
Tonsillectomy
Honey Used as Adjunct Therapy to Tylenol for Post-Op Tonsillectomy Patients
Tonsillectomies are the second most common surgery with over half a million procedures in the United States for 2006. Tonsillectomies are considered a painful surgical procedure performed on children resulting in pain and…
- Trial name
- NCT03931395
- Testing
- Honey, Standard of Care
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Esophageal Atresia, Enhanced Recovery After Surgery
Application of Enhanced Recovery After Surgery for Congenital Esophageal Atresia During Perioperative Period
The purpose of this prospective cohort study is to evaluate the safety and effectiveness of enhanced recovery after surgery (ERAS) to perform routine thoracoscopic repair for elective esophageal atresia type C
- Trial name
- ERASforCEA (NCT04072419)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Guangzhou Women and Children's Medical Center
Regional Anesthesia
Comparison of Caudal Block and Retrolaminar Block for Circumcision
Primary Outcome: Analgesic Efficiency: The primary outcome is the comparison of the analgesic efficacy of the retrolaminar block (RL) versus caudal block (CB) based on postoperative pain scores measured by the FLACC score.
- Trial name
- NCT06584292
- Testing
- caudal block, Retrolaminar block
- Where
- Turkey (Türkiye)
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
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