Clinical trials: Post-operative Nausea
Tonsillectomy, Pain
Betamethasone (Betapred®) as Premedication for Reducing Postoperative Vomiting and Pain After Tonsillectomy
Betamethasone is currently given routinely in conjunction with tonsillectomy surgery at the majority of Ear, Nose \& Throat clinics in Sweden.
- Conditions
- Tonsillectomy, Pain, PONV, Bleeding
- Trial name
- NCT03783182
- Testing
- Betamethason Sodium Phosphate, 10% glucose solution
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Umeå University
Postoperative Nausea and Vomiting
Aprepitant PO vs Ondansetron IV for Prevention of Postoperative Nausea and Vomiting
Postoperative nausea and vomiting (PONV) persists as one of the more common complications of surgery. Although rarely life-threatening, it is the postoperative outcome that is most unfavorable to patients, even more undesirable…
- Trial name
- NCT00699894
- Testing
- aprepitant 40 mg, ondansetron 4 mg
- Where
- United States
- Sponsor
- Northwell Health
Postoperative Nausea and Vomiting
Famotidine Versus Placebo in Emergency Pediatric Surgery As a Risk to Postoperative Nausea and Vomiting
The aim of this study is to evaluate the difference of the gastric volume by quantitative measurements of gastric antrum preoperatively and postoperatively by using 5mg famotidine versus placebo as a risk factor of PONV.
- Trial name
- NCT06211088
- Testing
- famotidine plus10ml normal saline, 10ml normal saline
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aswan University Hospital
Postoperative Nausea
Postoperative Nausea/Vomiting and Acupressure
Postoperative nausea and vomiting (PONV) remain a significant challenge in our practice. However, pharmaceutical prophylaxis can confer unpleasant adverse effects.
- Trial name
- Acunausea (NCT01389570)
- Testing
- Acupressure wrist band
- Where
- Norway
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Research Centre of Complementary and Alternative Medicine, Norway
Tonsillectomy
Here's the Buzz: Evaluating Pediatric Post Op Pain and Nausea Following Tonsillectomy Surgery
Tonsillectomy is one of the most common surgeries performed in the United States, with over half a million performed annually in children younger than 15 years of age.
- Trial name
- NCT04910919
- Testing
- Honey, Standard of Care
- Where
- United States
- Sponsor
- Vanderbilt University Medical Center
Penehyclidine, Postoperative Nausea and Vomiting
Penehyclidine and Postoperative Nausea and Vomiting After Bimaxillary Surgery
Postoperative nausea and vomiting (PONV) are common complications after surgery. Patients undergoing orthognathic surgery are reported to have a high rate of PONV, especially those undergoing bimaxillary surgery.
- Conditions
- Penehyclidine, Postoperative Nausea and Vomiting, Bimaxillar Surgery
- Trial name
- NCT04112771
- Testing
- Penehyclidine hydrochloride, No penehyclidine hydrochloride
- Where
- 2 sites in China
- Volunteers
- 243 people
- Sponsor
- Peking University First Hospital
Post Operative Nausea and Vomiting (PONV), Adenotonsillectomy
Gabapentin Premedication and Adenotonsillectomy in Pediatric Patients
The frequent incidence of postoperative vomiting and severe pain in children undergoing adenotonsillectomy, may delay postoperative oral intake and increase the risk of dehydration.
- Trial name
- NCT02384187
- Testing
- Gabapentin as premedication
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Cairo University
Emergence Delirium
The PREVENT AGITATION Trial II - Children ≤1 Year
Emergence agitation is a clinical condition in which the child experiences a variety of behavioural disturbances including crying, thrashing, and disorientation during early awakening from anaesthesia.
- Trial name
- NCT05091242
- Testing
- Clonidine, Sodium chloride
- Where
- 2 sites in Australia, Denmark
- Volunteers
- 336 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Postoperative Nausea and Vomiting
Late Onset Postoperative Nausea and Vomiting
The purpose of this trial is to study the effects of different combinations of antiemetics on the incidence of late onset postoperative nausea and vomiting.
- Trial name
- NCT00918190
- Testing
- Ondansetron, Dexamethasone, Midazolam, dexamethasone
- Where
- Saudi Arabia
- Volunteers
- 75 people
- Sponsor
- King Khaled Eye Specialist Hospital
Postoperative Nausea and Vomiting
Comp Granisetron Midazolam Comb in Lap Children
Postoperative nausea and vomiting (PONV) is one of the most common complications of general anesthesia in pediatrics. Pediatric rates of nausea and vomiting are approximately double those of adult patients.
- Trial name
- NCT03483350
- Testing
- Granisetron, Midazolam
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Ondansetron Lozenge, Postoperative Nausea and Vomiting
Preoperative Ondansetron Lozenge for Prevention of Postoperative Nausea and Vomiting in Pediatrics Undergoing Squint Surgeries
The aim of this study is to evaluate the role of ondansetron lozenge on prevention of postoperative nausea and vomiting (PONV) in pediatrics undergoing squint surgeries.
- Conditions
- Ondansetron Lozenge, Postoperative Nausea and Vomiting, Pediatrics, Squint
- Trial name
- NCT06423820
- Testing
- Ondansetron lozenge
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Postoperative Vomiting
Effect of Intravenous Fluid Therapy on Postoperative Vomiting in Children Undergoing Otorhinolaryngological Surgery
The purpose of this randomized clinical trial is to evaluate the interaction of intravenous fluid therapy during otorhinolaryngological surgery, on postoperative vomiting.
- Trial name
- NCT01575600
- Testing
- Intraoperative lactated Ringer's solution
- Where
- Chile
- Volunteers
- 100 people
- Sponsor
- Ignacio Cortínez F.
POSTOP NAUSEA VOMITING, Tonsillectomy
SNAKES Trial: Jelly Snakes to Prevent PONV in Kids After ENT Surgery
Postoperative nausea and vomiting in children is a common phenomenon, particularly after ear nose and throat (ENT) surgery. While it affects up to 80% of patients who do not receive preventative medication during their operation…
- Conditions
- POSTOP NAUSEA VOMITING, Tonsillectomy, Adenoidectomy
- Trial name
- NCT03879681
- Testing
- Jelly confectionary Snakes
- Volunteers
- 240 people
- Sponsor
- Prof. Thomas Engelhardt
Scoliosis, Spinal Deformity
Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal Deformations
Improving the anesthesiology management for surgical correction of spinal deformations with introducing the diagnostic methods and treatment strategy of acute pain, preventing the evolution of chronic pain.
- Conditions
- Scoliosis, Spinal Deformity, Acute Pain, Chronic Pain
- Trial name
- BBESPB (NCT04697498)
- Testing
- Bilateral bi-level Erector spine plane block, General anaesthesia
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Lviv National Medical University
Postoperative Nausea and Vomiting, Sore-throat
Do Throat Pack Used in Dental Treatments Under General Anesthesia of Patients Have an Effect on PONV and Sore Throat?
The aim of this study is to investigate the effect of throat packs on PONV in dental treatments under general anesthesia in special health care needs.
- Conditions
- Postoperative Nausea and Vomiting, Sore-throat, Dental Caries
- Trial name
- NCT06169306
- Testing
- throat pack
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Postoperative Pain, Postoperative Vomiting
Efficacy of Dexmedetomidine for Postoperative Analgesia in Infantile Cataract Surgery
The purpose of the present study was to evaluate the efficacy and safety of subtenon block (SB)anesthesia with dexmedetomidine in combination with bupivacaine versus intravenous dexmedetomidine for postoperative analgesia and…
- Trial name
- NCT02495220
- Testing
- SB dexmedetomidine bupivacaine block, intravenous dexmedetomidine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Postoperative Nausea and Vomiting (PONV)
Dexamethasone for Prevention of Postoperative Vomiting After Laparoscopic Gynecologic Surgery
Postoperative nausea and vomiting (PONV) are common and distressing complications following laparoscopic gynecologic surgery. This randomized controlled trial evaluated whether a single preoperative intravenous dose of…
- Trial name
- PONV-DEX-GYN (NCT07421817)
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Rawalpindi Medical College
Pain, Postoperative, Pruritus
Enhanced Recovery After Cesarean Section With Low Dose Intrathecal Morphine.
This study is designed to see the effect of low dose intrathecal morphine on promting enhanced recovery after cesarean delivery with early ambulation and reduction of hospital stay.
- Conditions
- Pain, Postoperative, Pruritus, Nausea, Postoperative, Vomiting, Postoperative
- Trial name
- NCT04618146
- Testing
- Morphine Sulfate, Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Minia University
Adolescent Idiopathic Scoliosis, Postoperative Pain, Acute
The Use of a Comfort Tote to Improve Recovery in Pediatric and Adolescent Patients After Surgery
The goal of this clinical trial is to learn if the use of Comfort Tote can treat pain and anxiety in adolescents with idiopathic scoliosis undergoing posterior spinal fusion. The study aims to answer two questions: 1.
- Conditions
- Adolescent Idiopathic Scoliosis, Postoperative Pain, Acute, Postoperative Nausea and Vomiting, Anxiety
- Trial name
- NCT07632833
- Testing
- The Therapeutic Comfort Tote, The Modified Comfort Tote
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Columbia University
Patient-Controlled Analgesia
Nausea and Vomiting in Postoperative Paediatric Patients With Patient-Controlled Analgesia (PCA): Morphine vs Oxycodone
POPCORN trial will compare the side effects and effectiveness of Morphine versus Oxycodone medication when prescribed for use as patient controlled analgesia (PCA) for pain relief for paediatric patients after-surgery.
- Trial name
- POPCORN (NCT06186141)
- Testing
- Morphine, Oxycodone
- Where
- Australia
- Volunteers
- 690 people
- Sponsor
- Murdoch Childrens Research Institute