Clinical trials: Postmenopausal Symptoms
Postmenopausal Symptoms, Telerehabilitation
Relaxation Training Via Tele-Rehabilitation in Postmenopausal Women
Menopause is associated with various physiological and psychological changes that may adversely affect women's quality of life. Menopausal symptoms, sleep disturbances, and fatigue are among the most common complaints during the…
- Conditions
- Postmenopausal Symptoms, Telerehabilitation, Relaxation Training, Menopause
- Trial name
- NCT07737691
- Testing
- Relaxation Training Delivered via Tele-Rehabilitation
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marmara University
Postmenopause
Use of the Synthetic Hormone CDB-2914 in Treating Symptoms of Menopause
This study will examine the safety and effectiveness of a synthetic hormone, CDB-2914, for treating symptoms of menopause. It will compare the effects of estrogen and CDB-2914 with those of estrogen and progesterone in…
- Trial name
- NCT00009659
- Testing
- CDB 2914
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Menopause
The Effect of Emotional Freedom Technique on Depressive and Menopausal Symptoms in Postmenopausal Women
The aim of this study is to determine the effect of EFT (Emotional Freedom Technique), a nonpharmacological method, on menopausal symptoms and depression in postmenopausal women.
- Trial name
- NCT06338085
- Testing
- emotional liberation technique
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Meryem Vural Şahin
Hypercholesterolemia, Postmenopause
Vascular and Metabolic Effects of Hormone Therapy Combined With L-Arginine in Postmenopausal Women
Estrogen therapy has been associated with reduced risk of coronary heart disease events in observational studies of postmenopausal women.
- Trial name
- NCT00001752
- Testing
- L-arginine, Estrogen
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Postmenopausal Osteoporosis
Pravastatin Reduces Acute Phase Response of Zoledronic Acid
Acute phase response (APR) is one of the most common adverse events in osteoporosis with zoledronic acid treatment. It's reported that this reaction is related to the blockade of the mevalonate pathway, leading to isopentenyl…
- Trial name
- NCT04719481
- Testing
- Pravastatin Sodium 80 MG
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Weak; Pelvic Floor, Weak; Muscle
Effect of the Pelvic Floor Training in Postmenopausal Women With or Without Hormonal Therapy
The purpose of this study is to evaluate the effect of pelvic floor muscle training (PFMT) on muscle function of postmenopausal women using or not using hormonal therapy replacement (HTR).
- Conditions
- Weak; Pelvic Floor, Weak; Muscle, Urinary Incontinence
- Trial name
- NCT02549729
- Testing
- pelvic floor muscle training
- Where
- Brazil
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Type 2 Diabetes, Inflammation
Effect of Alcohol on Cephalic Phase Reflex and Gene Expression
Moderate alcohol consumption has consistently been associated with lowered risk of developing type two diabetes mellitus compared to abstainers and heavy drinkers.
- Conditions
- Type 2 Diabetes, Inflammation, Carbohydrate&Lipid Metabolism, Oral Processing
- Trial name
- AR22 (NCT00652405)
- Testing
- alcohol
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- TNO
Hypertension, Dyslipidemia
Effect of Pumpkin Seed Oil or Pumpkin Seeds on Blood Pressure and Menopausal Symptoms in Postmenopausal Women
The purpose of this randomized control trial is to compare the effect of pumpkin seed oil 2g/day with pumpkin seeds given as a dose of 1½ teaspoons/ 4.1 grams a day to provide 2g of lipid (equivalent to 2 grams of oil) on BP…
- Trial name
- NCT02727036
- Testing
- Pumpkin seed oil, Pumpkin seeds
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Texas Woman's University
Cardiovascular Disease, Skin Health
Effects of Anthocyanin on Skin Health and Markers of Cardiovascular Disease Risk
The purpose of this study is to determine whether short-term exposure to a compound found in some fruits and vegetables (anthocyanin), is effective in improving skin health and reducing the levels of various markers of…
- Conditions
- Cardiovascular Disease, Skin Health, Postmenopause
- Trial name
- NCT00574574
- Testing
- anthocyanin
- Where
- United Kingdom
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Urinary Incontinence (UI), Postmenopause
The Effect of Sujok Therapy on Urinary Incontinence and Quality of Life in Postmenopausal Women
This study aims to investigate the effect of Su Jok therapy, a complementary medicine practice, on urinary incontinence and quality of life among postmenopausal women.
- Trial name
- NCT06951022
- Testing
- Sujok therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Inonu University
Sarcopenia
Protein Timing, Lean Mass, Strength and Functional Capacity Gains in Postmenopausal Women
This study evaluated the effect of protein intake immediately after resistance exercise on lean mass, strength, and functional capacity gains in postmenopausal women.
- Trial name
- NCT03372876
- Testing
- Protein and carbohydrate supplementation
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Sarcopenia
High vs Normal Protein Diets, Resistance Exercise, Lean Mass and Strength Gains
This study evaluates the effect of different types of diets (high and normal protein) on lean and fat mass, and strength in postmenopausal women practitioners of resistance exercise.
- Trial name
- NCT03024125
- Testing
- High protein, Normal protein, Training
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Menopause
The Effect of Soya Foods on Cognitive Function and Menopausal Symptoms in Postmenopausal Women.
Participants will be randomly assigned to one of three treatment groups to receive soyafoods (Alpro drinks) providing a low (<10 mg), medium (35mg) or high-dose (60 mg) of isoflavones daily for a period of 12 weeks.
- Trial name
- NCT03561662
- Testing
- Alpro soya drinks
- Where
- United Kingdom
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Postmenopausal Symptoms, Hot Flashes
WHAT (Women, Hot-flashes, Activity, Trial) - Physical Activity for Treatment of Hot Flushes Among Postmenopausal Women
More than 60 % of women experience hot-flashes during postmenopausal and 20 % have serious symptoms. Use of combined estrogen/progesterone therapy reduces hot-flashes effectively.
- Trial name
- WHAT (NCT01282320)
- Testing
- Physical activity intervention program
- Where
- Norway
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Vulvovaginal Atrophy, Vasomotor Symptoms
Study of DARE-HRT1 Over 12 Weeks in Healthy PostMenopausal Women
Randomized, Open-label 2-arm, parallel group study in approximately 20 healthy postmenopausal women to assess the safety of DARE-HRT1 Intravaginal Rings in two different dose strengths and the PK of progesterone and estradiol…
- Trial name
- DARE-HRT1 (NCT05367973)
- Testing
- IVR Dose 1, IVR Dose 2
- Where
- 2 sites in Australia
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Daré Bioscience, Inc.
Hot Flashes
Amino Acid Therapy for Hot Flashes in Postmenopausal Women
The purpose of this study is to determine the safety, tolerability, and effectiveness of the amino acid L-isoleucine in the treatment of hot flashes in postmenopausal women.
- Trial name
- NCT00081952
- Testing
- L-norleucine
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Dyslipidemias, Hypertriglyceridemia
Effects of Phytoestrogen From Pueraria Mirifica in Improvement of Serum Lipid Parameters in Postmenopausal Women
The goal of this clinical trial is to learn about the effects of phytoestrogen from Pueraria Mirifica in improvement of serum lipid parameters.
- Conditions
- Dyslipidemias, Hypertriglyceridemia, Hypercholesterolemia, Hyper-LDL-cholesterolemia
- Trial name
- NCT06220266
- Testing
- Phytoestrogen, Diet control & life style modification
- Where
- Thailand
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Dhurakij Pundit University
Obesity
Diet Composition - Metabolic Regulation and Long-term Compliance
This study will compare a high-protein/low-carbohydrate diet (modified paleolithic diet, MPD) with a diet high in slow carbohydrates (Nordic Nutrition Recommendations, NNR).
- Trial name
- KNOTA (NCT00692536)
- Testing
- NNR (Nordic Nutrition Recommendations), MPD (Modified paleolithic diet)
- Where
- Sweden
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Umeå University
Vulvovaginal Atrophy, Vasomotor Symptoms
A Phase 1, Open-Label, Parallel Group Study to Evaluate the Pharmacokinetics and Safety of DARE-HRT1 in Healthy PostMenopausal Women
An open-label study to assess the PK of estradiol, estrone and progesterone from the DARE-HRT1 intravaginal rings at two different dose strengths.
- Trial name
- NCT05418426
- Testing
- IVR Dose 1, IVR Dose 2, Oral Reference
- Where
- 2 sites in Australia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Daré Bioscience, Inc.
Obesity, Postmenopausal Women
Tocotrienols for Obesity of Postmenopausal Women
Postmenopausal women are at a risk of excessive weight gain, bone loss, hypertension, and metabolic syndrome. Obesity-induced chronic low-grade inflammation is initiated by excess nutrients in metabolic cells.
- Trial name
- VitE-obesity (NCT03705845)
- Testing
- DeltaGold® Tocotrienol 70%
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center