Clinical trials: Postoperative Confusion
Postoperative Nausea, Postoperative Vomiting
Influence of Monitoring the Depth of General Anesthesia Upon the Incidence of PONV and Emergence Delirium in Children Undergoing Endoscopic Adenoidectomy in General Anesthesia
The study has been designed as a prospective randomized clinical trial. Due to the use of a bispectral (BIS) monitor in the interventional arm, the study will not be blinded for the anesthetist.
- Conditions
- Postoperative Nausea, Postoperative Vomiting, Emergence Delirium
- Trial name
- NCT04466579
- Testing
- BIS monitor, Standard care
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Ostrava
Delirium
Different Doses of Sevoflurane During Induction of Anesthesia on Emergence Delirium in Children
The investigators aim to reduce the incidence of emergence delirium in children aged 2-7 years old by using two different doses of sevoflurane during inhalatory induction of anesthesia.
- Trial name
- NCT02707016
- Testing
- Sevoflurane 8%, Sevoflurane 5%
- Where
- Chile
- Volunteers
- 80 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Emergency Delirium, Postoperative Delirium (POD)
Comparison of IV Dexmedetomidine Versus Clonidine Versus no Alpha 2 Agonist on Emergency Delirium, PACU Length of Stay and Time to Hospital Discharge in Children Undergoing (Adeno)Tonsillectomy: a Prospective Observational Study
Emergence delirium (ED) is a frequent complication in children undergoing general anesthesia, particularly following ENT procedures such as adenotonsillectomy.
- Conditions
- Emergency Delirium, Postoperative Delirium (POD), Adenotonsillectomy, Tonsillectomy
- Trial name
- CLONIDEX (NCT07913308)
- Testing
- Intravenous dexmedetomidine, Intravenous clonidine, Standard Anesthetic Care Without Alpha-2 Agonist
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Universitair Ziekenhuis Brussel
Emergence Agitation
Effect of Dexmedetomedine in Subtenon's Block on Emergence Agitation in Pediatric Strabismus Surgery
The study is conducted to evaluate the effects of dexmedetomedine in subtenon's block in conjunction to general anesthesia under sevoflurane anesthesia on emergence agitation, intraoperative hemodynamic stability, postoperative…
- Trial name
- NCT04485273
- Testing
- Laryngeal Mask Airway, Sevoflurane, Subtenon's Block
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sameh Fathy
Emergence Agitation
Comparison of Effect of Dexmedetomidine and Midazolam on Emergence Agitation
Since the frequency of emergence agitation (EA) is relatively high in children while undergoing nasal surgery, and there is not much data available in Pakistan regarding EA in adults undergoing functional endoscopic sinus surgery…
- Trial name
- NCT07392983
- Testing
- Dexmedetomidine, Midazolam
- Where
- 2 sites in Pakistan
- Volunteers
- 146 people
- Sponsor
- Muhammad Aamir Latif
Remimazolam, Tonsillectomy
Remimazolam for Emergence Delirium Prevention in Children Undergoing Tonsillectomy
The aim of this study is to confirm the effectiveness of remimazolam in preventing delirium during emergence from anesthesia in children who will undergo elective procedures of tonsillectomy, adenotonsillectomy or adenoidectomy…
- Conditions
- Remimazolam, Tonsillectomy, Emergence Delirium
- Trial name
- NCT07704437
- Testing
- Remimazolam 20 MG Injection [Byfavo], NaCl (0,9%)
- Where
- Croatia
- Volunteers
- 110 people
- Sponsor
- University Hospital of Split
Emergence Delirium, Anesthesia
Effect of Different Drugs on Emergency Delirium in Preschool Age Patient
Emergence delirium (ED) was first described by Eckenhoff and colleagues in the 1960s and is defined in pediatric anesthesia as 'dissociated state of consciousness in which child is irritable, uncompromising, uncooperative…
- Trial name
- NCT07057193
- Testing
- Dexmedetomidine group (D group), Ketamine group (K group), Midazolam group (M group)
- Where
- Egypt
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Delirium on Emergence
Sevoflurane/Dexmedetomidine vs. Isoflurane for Pediatric Emergence Delirium
The purpose of this study is to measure the incidences of pediatric emergence delirium between the group receiving Isoflurane and the group receiving Sevoflurane plus intravenous push dexmedetomidine.
- Trial name
- NCT06624592
- Testing
- Sevoflurane, Isoflurane
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Mayo Clinic
Lactium, Emergence Agitation
Preemptive Oral Lactium to Prevent Emergence Agitation
This prospective randomized controlled study will be conducted to evaluate the effects of preoperative lactium on the incidence and severity of emergence agitation in children undergoing adenotonsillectomy using sevoflurane…
- Conditions
- Lactium, Emergence Agitation, Adenotonsillectomy
- Trial name
- NCT07172594
- Testing
- Lactium
- Where
- Egypt
- Volunteers
- 135 people
- Sponsor
- Tanta University
Post Operative Pain Management in Children With Tonsillectomy/Adenoidectomy
Preoperative Gabapentin for Post-tonsillectomy Pain in Children
The typical post-operative course for children following surgical removal of their tonsils and adenoids can be challenging, especially for pain control.
- Trial name
- NCT01707420
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Colorado, Denver
Cerebral Oxygen Saturation, Postoperative Delirium
Association Between Local Cerebral Oxygenation Monitoring and Postoperative Delirium in Carotid Endarterectomy
Postoperative delirium (POD) is a common perioperative complication, which can lead to adverse outcomes. Patients undergoing carotid endarterectomy (CEA) were elderly, complicated with vascular risk factors, cognitive…
- Conditions
- Cerebral Oxygen Saturation, Postoperative Delirium, Carotid Endarterectomy
- Trial name
- NCT05198635
- Testing
- local cerebral oxygen saturation
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Beijing Tiantan Hospital
Delirium - Postoperative, Anxiety Acute
Pediatric Recovery Delirium in Pediatric Patients Undergoing Surgery
The primary aim of this observational study is to evaluate the effect of playing a mother's voice to a child while the patient is being awakened from anesthesia on postoperative delirium.
- Trial name
- Delirium (NCT07413289)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Enes Celik
Transient Ischemic Attack, Acute Stroke
the Research of the Cerebral Protection Effects of Electroencephalogram (SedLine) During Carotid Endarterectomy
Fragile brain is the most common phenomenon seen in the patients undergoing CEA. The patients with fragile brain have a high incidence of postoperative brain dysfunction.
- Conditions
- Transient Ischemic Attack, Acute Stroke, Postoperative Delirium, Postoperative Cognitive Dysfunction
- Trial name
- NCT03622515
- Testing
- Anesthesia level and cerebral perfusion pressure
- Where
- 2 sites in China
- Volunteers
- 220 people
- Sponsor
- Beijing Municipal Administration of Hospitals
Effect of Drug, Complication of Treatment
Dexmedetomidine as a Sole Premedication for BMT Placement
There is very little evidence or research documenting any single method of sedation/analgesia for myringotomy tube (BMT) placement as being more effective than others.
- Trial name
- BMT (NCT05903326)
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 276 people
- Sponsor
- Nemours Children's Clinic
Emergence Delirium
Effect of Fentanyl on Emergence Delirium (ED) on Children Undergoing Adeno-tonsilectomy at Kenyatta National Hospital (KNH)
This study will be a randomized double blind placebo controlled clinical trial among children undergoing adeno-tonsillectomy in KNH.
- Trial name
- NCT02753725
- Testing
- Fentanyl, Normal saline
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Nairobi
Emergence Delirium, Temperament
The Effect of Pediatric Patient Temperament on Postoperative Outcomes
The goal of this study is to determine if preoperative temperament is associated with postoperative pain, emergence agitation, emotional and behavioral changes, and overall parent satisfaction.
- Trial name
- NCT04224324
- Testing
- Tonsillectomy and Adeniodectomy
- Where
- United States
- Volunteers
- 344 people
- Sponsor
- Boston Children's Hospital
Delirium
The Delirium-CS Canada Study
Delirium is a prevalent complication following cardiac surgery that is under-recognized using current methods of delirium detection and that may be better identified through a systematic and standardized perioperative screening…
- Trial name
- DELIRIUM-CS (NCT02206880)
- Where
- 12 sites in Canada
- Volunteers
- 235 people
- Sponsor
- St. Boniface Hospital
Emergence Delirium, Delirium - Postoperative
Nebulized Dexmedetomidine for Post-Anesthesia Delirium in Preschool Children
Analyzing the effectiveness of nebulized dexmedetomidine 2 mcg/kg in reducing the incidence of post-anesthesia delirium in preschool children undergoing elective surgery with sevoflurane inhalation general anesthesia.
- Trial name
- NCT06761092
- Testing
- Nebulized Dexmedetomidine for Post-Anesthesia Delirium in Preschool Children, Nebulized 0.9% Normal Saline
- Where
- Indonesia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Udayana University
Agitation, Emergence, Post Operative Pain
Effect of Caudal Nalbuphine on Postoperative Emergence Agitation in Pediatrics Undergoing Infra-umbilical Surgeries
Effect of caudal nalbuphine on postoperative emergence agitation in pediatrics undergoing infra-umbilical surgeries and pain assessment
- Trial name
- NCT05245721
- Testing
- Nalbuphine, Bupivacain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Emergence Delirium
Emergence Agitation of Sevoflurane in Pediatric
Low dose nalbuphine versus dexmedetomidine on prevention of emergence agitation in children
- Trial name
- NCT06830564
- Testing
- we will give the patient 0.1 mg nalbuphine 15 min before the end of the procedure, we will give the patient 0.5 mg dexmedetomidine 15 min before the end of the procedure
- Where
- Egypt
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Ain Shams University