Clinical trials: Postoperative Pain Relief
Lower Abdominal Surgery
Erector Spinae Plane Block for Peroperative Analgesia and Intraabdominal Tissue Oxygenation
Brief summary: Regional anesthesia decreases the need for intravenous analgesia in the peri-operative period. Erector spinae plane (ESP) is a regional anesthesia technique shown to be effective at the dorsal and ventral rami of…
- Trial name
- ESPB (NCT03808129)
- Testing
- Bupivacaine and Lidocaine
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Caudal Block for Postoperative Analgesia
Effect of Adding Different Concentrations of Dexmedetomidine to Bupivacaine in Caudal Block for Pediatrics
Pain is one of the medical problems frequently misdiagnosed, undertreated, and poorly under-stood, particularly in children.Poor pain management during childhood may have long-term deleterious impacts, including damaging…
- Trial name
- NCT06668220
- Testing
- Dexmedetomidine, Bupivacain
- Volunteers
- 50 people
- Sponsor
- Assiut University
Analgesia
Postoperative Analgesia by Epidural vs IV Ketamine Concurrent With Caudal Anesthesia in Pediatric Orthopedic Surgery
Preemptive analgesia can improve postoperative pain management. Ketamine may prevent central sensitization during surgery and result in preemptive analgesia.
- Trial name
- NCT00532662
- Testing
- S(+)-ketamine
- Where
- 2 sites in Iran
- Volunteers
- 40 people
- Sponsor
- Tehran University of Medical Sciences
Pertrochanteric Fracture, Pain, Postoperative
Pericapsular Nerve Group Block for Positional Pain and Postoperative Analgesia in Hip Fractures
The aims of this study are: Evaluate the effectiveness of the pericapsulare blockade of the femoral nerve, the accessory obturator nerve and the obturator nerve in patients with pertrochanteric fractures of the femur, during the…
- Trial name
- NCT05079087
- Testing
- Pericapsular nerve group blockade, Midazolam Ketamine arm
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Azienda Sanitaria dell'Alto Adige
Efficacy of Erector Spinae Plane Block in Lower Limb Surgery in Pediatric
Erector Spinae Plane Block in Pediatric Lower Limb Surgery
Anesthesia will be induced in all patients using Fentanyl 1µg,propofol 2mg/kg and cisatracurium 0.15 mg/kg IV to facilitate endotracheal intubation, maintenance of anaesthesia afterward will be achieved by isoflurane1.5-2% in…
- Trial name
- NCT05369455
- Testing
- erector spinae plane block, ultrasound guided caudal block
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tanta University
Coarctation of Aorta
The Effect of Paravertebral Block With Dexamethasone on Intraoperative and Postoperative Analgesia in Children Undergoing Surgery for Coarctation of Aorta
Anesthetic management for surgery of aortic coarctation needs special care due to severe pain during lateral thoracotomy incision, the intraoperative hemodynamic instability related to skin incision at lateral thoracotomy…
- Trial name
- NCT03074773
- Testing
- Dexamethasone, ultrasound, paravertebral block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Postoperative Pain
Intravenous Dexmedetomidin on Postoperative Pain After Hypospadias Repair in Children
This study aimed to evaluate the efficacy of intravenous ketorolac versus dexmedetomidine as analgesia after Hypospadias repair surgery to determine the optimal procedure for pain control and postoperative reduction of analgesic…
- Trial name
- NCT05194904
- Testing
- Dexmedetomidine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Post Operative Pain
Ultrasound-Guided Lumbar Erector Spinae Plane Block Versus Caudal Block for Postoperative Analgesia in Hip and Proximal Femur Surgery in Pediatric Patients
The study will compare Ultrasound-Guided Lumbar Erector Spinae Plane Block and caudal block for Postoperative Analgesia in Hip and Proximal Femur Surgery in pediatric patients
- Trial name
- NCT05157516
- Testing
- erector spinea block, Caudal epidural block
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Cairo University
Anesthesia, Oxycodone
Evaluating the Analgesic Efficacy of Oxycodone Hydrochloride in Pediatric Laparoscopic Cryptorchidism Surgery
Cryptorchidism surgery is a common pediatric procedure, often performed laparoscopically to reposition undescended testes into the scrotum.
- Conditions
- Anesthesia, Oxycodone, Analgesia, Postoperative
- Trial name
- Anesthesia (NCT06665048)
- Testing
- Oxycodone HCl
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Shantou University Medical College
Laparoscopic Cholecystectomy, Post Operative Analgesia
Postoperative Pain After Instillation Of Bupivacaine During Laparoscopic Cholecystectomy
This study aims to compare the level of postoperative pain experienced by patients undergoing laparoscopic cholecystectomy with and without the use of intraperitoneal bupivacaine.
- Conditions
- Laparoscopic Cholecystectomy, Post Operative Analgesia, Bupivacaine
- Trial name
- BUPA-LC (NCT07098429)
- Testing
- Bupivacain (Postoperative), Normal (0.9%) saline
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan Hospital Pakistan - Muzaffargarh
Pain, Postoperative, Knee Arthroscopy
Postoperative Pain Between ACB and FNB After ACLR
The aim of this study is to compare the efficacy in pain relief within 24 hours between adductor canal block and femoral nerve block after anterior cruciate ligament reconstruction with hamstring graft.
- Conditions
- Pain, Postoperative, Knee Arthroscopy, Anterior Cruciate Ligament/Surgery
- Trial name
- NCT02411890
- Testing
- Adductor canal block (active), Femoral nerve block (active)
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Thammasat University
Anesthesia, Opioid Use
Opioid-Free Anesthetic for Tonsillectomy
Prospective randomized controlled trial to determine if opioid-free anesthetic for tonsillectomy is non-inferior to standard opioid-containing anesthetic
- Conditions
- Anesthesia, Opioid Use, Tonsillitis, Sleep Disorder
- Trial name
- NCT04528173
- Testing
- Ketorolac, Dexmedetomidine, Morphine
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Cholelithiasis, Postoperative Pain, Laparoscopic Cholecystectomy
ESP vs Subcostal TAP Block for Analgesia After Laparoscopic Cholecystectomy
This prospective, randomized, double-blind study compares the analgesic efficacy of ultrasound-guided erector spinae plane (ESP) block and subcostal transversus abdominis plane (TAP) block in patients undergoing laparoscopic…
- Trial name
- ESP TAP (NCT07661693)
- Testing
- Erector Spinae Plane Block, Subcostal Transversus Abdominis Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Gaziantep City Hospital
Knee Arthropathy, Anesthesia, Local
Modified TIPS Block for Total Knee Arthroplasty
The is carried out to compare triple injection peri-sartorial block to a modified block including an extra local anesthetic injection deep to the adductor longs muscle via a medial to lateral approach regarding the peri-operative…
- Trial name
- NCT06539910
- Testing
- General Anesthesia, TIPS block, Modified TIPS block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Alexandria University
Post Operative Pain, Stress Response
Effects of Erector Spinae Plane and Caudal Block on Postoperative Stress Response
Inguinal hernia surgery is the most common practice of pediatric surgeons in their clinical practice. As these operations are usually day case procedures, maintaining adequate analgesia is an important component of perioperative…
- Conditions
- Post Operative Pain, Stress Response, Erector Spinae Plane Block, Caudal Block
- Trial name
- NCT05633173
- Testing
- Ultrasound-guided erector spinae plan block, Ultrasound-guided caudal block
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Post-operative Pain, Quadriceps Muscle Strength
Ultrasound Guided Adductor Canal Versus Femoral Nerve Blocks for Anterior Cruciate Ligament Reconstruction in Pediatrics
Both Ultrasound guided Adductor Canal Block ( ACB) and Femoral Nerve Block (FNB) has been used to provide postoperative analgesia for knee surgeries.
- Trial name
- NCT03053401
- Testing
- Adductor Canal Block, Femoral Nerve Block, Ultrasound
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Akron Children's Hospital
Pain
Parasternal Nerve Block Using Bupivacaine for Postoperative Analgesia in Children Undergoing Cardiac Surgery
All pediatric patients who undergo cardiac surgery require analgesic medications for postoperative pain control and many require sedation to facilitate comfort with cares.
- Trial name
- NCT02512861
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Postoperative Analgesia
Comparison of the Effects of Sacral Erector Spinae Plane Block and Dorsal Penile Block on Postoperative Pain in Circumcision Procedures
Egypt performed circumcision in 2300 BC, although its origin is unknown. Some societies use circumcision for health, whereas others do it for religious and cultural reasons .
- Trial name
- NCT06843070
- Testing
- PENILE BLOCK ARM, SACRAL ESP BLOCK ARM
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Anesthesia, Abdominoplasty
Efficacy of Postoperative Epidural Anesthesia Following Abdominoplasty
Effective postoperative pain management is essential for patient satisfaction and therefore intraoperative regional nerve blocks have become more and more popular in abdominoplasties.
- Trial name
- EDA (NCT05822882)
- Testing
- Epidural anesthesia
- Where
- Germany
- Volunteers
- 112 people
- Sponsor
- Klinik Bogenhausen
Postoperative Analgesia, Morphine and Dexmedetomidine
Compare Morphine and Dexmedetomidine as Adjuvants to Bupivacaine in Ultrasound-guided ACB for Postoperative Analgesia After Knee Surgeries
This study aims to compare morphine and dexmedetomidine as adjuvants to bupivacaine in ultrasound-guided ACB for postoperative analgesia after knee surgeries
- Trial name
- NCT07240402
- Testing
- Adductor Canal Block (ACB) Only
- Volunteers
- 15 people
- Sponsor
- Kafrelsheikh University