Clinical trials: Postprandial Glucose
Diabetes Mellitus, Type 1
Joint Application of Human Insulin and Rapid Insulin Analogue in Control of Postprandial Glycemia
Postprandial glycemic control is essential for diabetes compensation. Insulin pump therapy control blood glucose released in response to both high and low glycemic index carbohydrates in a mixed diet using normal, square and…
- Trial name
- CPIT (NCT01088451)
- Testing
- Combined prandial insulin therapy (CPIT)
- Where
- Czechia
- Volunteers
- 20 people
- Sponsor
- University Hospital Hradec Kralove
Type1 Diabetes
Effect of Dual-wave Insulin Bolus on Postprandial Glycaemia
A study was conducted in adolescents with type 1 diabetes (T1D) examining the effect of different bolus types on 6-h postprandial glucose levels after the consumption of 3 standard meals with varying composition.
- Trial name
- NCT03179280
- Testing
- insulin
- Where
- Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Type 1 Diabetes
Pramlintide in Adolescents With Type 1 Diabetes
The investigators hypothesize that subcutaneous pramlintide as an adjunct to mealtime insulin immediately prior to meals can significantly reduce post-prandial glucose concentrations compared with mealtime insulin alone in…
- Trial name
- NCT00842075
- Testing
- pramlintide
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Colorado, Denver
Overweight, Obesity
Meta-analyses of the Effect of 'Catalytic' Doses of Fructose and Its Epimers on Carbohydrate Metabolism
Despite advances in the prevention and treatment of type 2 diabetes, its prevalence continues to rise worldwide. There is a need for new modalities to improve metabolic control in individuals with type 2 diabetes and those who…
- Conditions
- Overweight, Obesity, Dysglycemia, Prediabetes
- Trial name
- NCT02776722
- Testing
- fructose, allulose, tagatose, or sorbose
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Childhood Obesity, Endothelial Dysfunction
Mechanisms of Atherogenesis During Post-prandial Time in Childhood Obesity
Childhood obesity is increasing at a fast pace, together with its complications. The aim of the present study is to assess several candidate triggering agents, mechanisms and intermediate phenotypes of atherosclerosis during the…
- Conditions
- Childhood Obesity, Endothelial Dysfunction, Inflammation, Insulin Resistance
- Trial name
- NCT01502826
- Testing
- standardized mixed meal
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Polycystic Ovarian Syndrome, Obesity
Post-Prandial Liver Glucose Metabolism in PCOS
The Investigators will measure if hepatic metabolism is upregulated in obese girls with PCOS and hepatic steatosis (HS), compared to PCOS without HS and obese controls without HS.
- Conditions
- Polycystic Ovarian Syndrome, Obesity, Hepatic Steatosis
- Trial name
- PLUM (NCT03041129)
- Testing
- oral glucose tolerance test, MRI of liver
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Personalized Nutrition In Children, Glucose, High Blood
Personalizing Mediterranean Diet in Children.
Investigating glucose response to Mediterranean and regular diets in healthy children in order to develop specific pediatric machine-learning for predicting the personalized glucose response to food for individual children.
- Conditions
- Personalized Nutrition In Children, Glucose, High Blood, Diet Habit
- Trial name
- NCT03627923
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Weizmann Institute of Science
Type 1 Diabetes
Closed-loop Control of Postprandial Glucose Levels in Children and Adults With Type 1 Diabetes
Current intensive insulin therapy in T1D involves prandial insulin boluses depending on the carbohydrate content of each ingested meal.
- Trial name
- NCT02490098
- Testing
- 6-day intervention with sensor-augmented pump therapy, 6-day intervention with single-hormone closed-loop strategy, 6-day intervention with dual-hormone closed-loop strategy
- Where
- Canada
- Sponsor
- Institut de Recherches Cliniques de Montreal
Type 1 Diabetes
Extended Bolus for Meals in a Closed-loop System
This study aims to evaluate whether the use of an extended bolus will improve glucose control with high-fat high protein meals using a closed-loop system.
- Trial name
- NCT05454891
- Testing
- Tandem t:slim X2 insulin pump: Extended bolus of insulin then standard bolus of insulin, Tandem t:slim X2 insulin pump: Standard bolus of insulin then extended bolus of insulin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Type 1 Diabetes
Acceleration of Insulin Action by Hyaluronidase During Closed-Loop Therapy
"Closed loop artificial pancreas" systems have been under development for the control of blood sugars in those living with diabetes.
- Trial name
- NCT01945099
- Testing
- ePID closed loop system, hyaluronidase, Lispro-PH20
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Yale University
Type 1 Diabetes, Type 1 Diabetes Mellitus
Alleviating Carbohydrate Counting for Patients With Type 1 Diabetes Using a Novel Insulin-plus-pramlintide Artificial Pancreas
One of the main challenges in maintaining tight glucose control in a closed-loop system occurs at meal times. Amylin is a gluco-regulatory beta-cell hormone that is co-secreted with insulin in response to nutrient stimuli, and is…
- Conditions
- Type 1 Diabetes, Type 1 Diabetes Mellitus, Hyperglycemia, Postprandial
- Trial name
- NCT04163874
- Testing
- Fiasp, Pramlintide Acetate, Artificial Pancreas
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- McGill University
Type 1 Diabetes Mellitus
The Effect of Insulin Glulisine Compared With Insulin Aspart on Breakfast Post Prandial Glucose Levels in Prepubertal Children
To determine whether insulin glulisine decreases the breakfast post prandial glycemic excursion in comparison to insulin aspart.
- Trial name
- NCT00913497
- Testing
- insulin glulisine, insulin aspart
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Corewell Health West
Type 2 Diabetes Mellitus, Postprandial Hyperglycemia
Effects of Insulin Treatment on Postprandial Platelet Activation in Patients With Non-insulin-dependent Diabetes Mellitus (NIDDM)
The postprandial phase in diabetic patients is characterized by a rapid increase in blood glucose levels, increase in platelet aggregation, LDL oxidation and over production of thrombin.
- Trial name
- NCT00771693
- Testing
- Insulin aspart (Novorapid®)
- Where
- Sweden
- Volunteers
- 18 people
- Sponsor
- Karolinska Institutet
Type 2 Diabetes
The Effect of Byetta and Symlin on Post-meal Meal Blood Sugar Levels in Children With Type 2 Diabetes
The purpose of this study is to see if giving study drugs before a meal may lower blood sugars after the meal. An improvement in blood sugar control may prevent long-term problems of diabetes.
- Trial name
- T2DM (NCT00950677)
- Testing
- Byetta (exenatide), Symlin (pramlintide)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Baylor College of Medicine
Diabetes Mellitus, Type 1
Exercises on Children and Adolescents With Type 1 Diabetes Mellitus (T1DM)
This study aimed to assess the effect of aerobic and resistance exercise on postprandial blood glucose levels in children and adolescents aged 10 - 18 years, diagnosed with type 1 diabetes mellitus (T1DM) for at least 1 year…
- Trial name
- NCT06680557
- Testing
- Aerobic and resistance exercises
- Where
- Egypt
- Volunteers
- 49 people
- Sponsor
- Sohag University
Type 1 Diabetes Mellitus
Continuous Glucose Monitoring to Measure Effect of Glycemic Index
Background: Post-prandial hyperglycemia is common in people with type 1 diabetes. Objective: The aim was to determine the impact of low vs high glycemic index (GI) on post-prandial glycemia for breakfast vs lunch and to quantify…
- Trial name
- NCT01145547
- Testing
- Dexcom Seven® Plus Continuous Glucose Monitoring sensor
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Legacy Health System
Type 1 Diabetes Mellitus
Insulin Glulisine and Aspart in Postprandial Glycemic Control After High-GI Meal in Children With Type 1 Diabetes Mellitus
The aim of this study is to determine whether insulin glulisine is more effective in postprandial glycemic control than insulin aspart after the H-GI meal in children with type 1 diabetes (T1DM) treated with insulin pump (CSII).
- Trial name
- NCT01678235
- Testing
- Insulin glulisine, Insulin aspart
- Where
- Poland
- Volunteers
- 64 people
- Sponsor
- Medical University of Warsaw
Type 2 Diabetes Mellitus
Lipid, Glycemic, and Insulin Responses to Meals Rich in Different Fatty Acids
A meal rich in very-long chain omega-3 fatty acids or oleic acid may lower postprandial insulin levels in comparison to a meal rich in linoleic acid or palmitic acid.
- Trial name
- NCT00479791
- Testing
- Test meals rich in different fatty acids
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Texas Southwestern Medical Center
Diabetes Mellitus, Type 1
Super-Bolus: Effects on Postprandial Glycemia After High Glycemic Index Meal
The aim of this study is to determine whether Super-Bolus is more effective in postprandial glycemic control than Normal-Bolus after the high glycemic index (H-GI) meal in children with type 1 diabetes (T1DM) treated with insulin…
- Trial name
- NCT04019821
- Testing
- Insulin Glulisine, Insulin Aspart, Insulin Lispro
- Where
- Poland
- Volunteers
- 72 people
- Sponsor
- Medical University of Warsaw
Type 1 Diabetes
Effect of Apidra Compared to Humalog in Decreasing Post-Prandial Hyperglycemia
This study aims to compare the post-meal blood glucose values of two drugs in a "real-world" setting.
- Trial name
- NCT01621776
- Testing
- Apidra, Humalog, Novolog
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- University of Florida