Clinical trials: Practice
Prostate Cancer, Hormone Sensitive Prostate Cancer
Evaluation of Clinical Outcomes of Chemotherapy or Androgen-receptor Targeting Agent (Alone or Combined) or Radiotherapy on Primary Tumor in Addition to Androgen Deprivation Therapy in HOrmone-Sensitive Metastatic Prostate Cancer Patients
The aim of this observational study is to evaluate the clinical outcomes of treatment with docetaxel, ARTA (alone or in combination) or with radiotherapy on the primary tumor for mCSPC, in an unselected population, in clinical…
- Conditions
- Prostate Cancer, Hormone Sensitive Prostate Cancer, Metastatic Tumor
- Trial name
- ECHOS (NCT06473259)
- Testing
- Docetaxel, Apalutamide Oral Tablet, Enzalutamide Oral Tablet
- Where
- 3 sites in Italy
- Volunteers
- 3,000 people
- Sponsor
- Santa Chiara Hospital
Thyroid Cancer, Mediastinal Diseases
Lateral Approach for Mediastinal Lymph Node Dissection in Thyroid Cancer
Despite the numerous surgical approaches available for superior mediastinal lymph node dissection in thyroid cancer, many of these methods still have significant limitations.
- Conditions
- Thyroid Cancer, Mediastinal Diseases, Lymph Node Metastasis
- Trial name
- NCT06793579
- Where
- China
- Volunteers
- 21 people
- Sponsor
- Chongqing General Hospital
Congenital Heart Defects, Heart Valve Diseases
Cardiac Operation Under Totally Endoscope and Cardiopulmonary Bypass (CPB)
Conventional cardiac operations are performed with median sternotomy, which is related to great wound, morbidities, longer duration in hospital and most significantly, cosmetic problems.
- Trial name
- CPB (NCT00921596)
- Testing
- cardiac operation with totally endoscopic method
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Xijing Hospital
Human Papilloma Virus (HPV) Vaccine
Knowledge, Attitude &Practice on Human Papilloma Virus Vaccination Among Healthcare Providers and General Population
Cervical cancer is caused by persistent infection with certain strains of the human papillomavirus (HPV), which is a very common virus transmitted through sexual activity.
- Trial name
- NCT06743880
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- Assiut University
Parenting Practices, Self Efficacy
Talk Parenting Education Program II
The goal of this clinical trial is to learn whether Talk Parenting, a voice-based program delivered through an Amazon Echo Dot (Alexa), can help parents and caregivers of children ages 3-5 years improve challenging bedtime and…
- Conditions
- Parenting Practices, Self Efficacy, Stress, Child Behavior
- Trial name
- TP2 (NCT07462052)
- Testing
- The Talk Parenting Program
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Dementia
Implementation Study of Dementia Guidelines in Primary Care
The purpose of this study is to determine whether a specially developed Dementia Training Program for duos of general practitioners and primary care nurses is able to increase the number dementia diagnoses in elderly people…
- Trial name
- NCT00459784
- Testing
- Dementia Training Program
- Where
- Netherlands
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Pediatric Growth Hormone Deficiency
A Study to Compare the Experiences of Taking Daily Growth Hormone Injections to Weekly Ngenla in Children With Low Levels of Growth Hormone
The purpose of this study is to learn about: how children stick to taking their injections their experience with the study medicines (Ngenla and daily growth hormone) prescribed to children with low levels of growth hormone.
- Trial name
- NCT06113952
- Testing
- Sharps bin to collect used needles/injections
- Sponsor
- Pfizer
Lung Cancer
Treatment Patterns, Outcomes and Testing in EGFRm NSCLC Patients With EGFR TKI 1L Across Europe (REFLECT)
Multinational, multi-center medical record review to describe the treatment patterns, clinical outcomes, and EGFR / T790M testing practices in EGFR-mutated advanced NSCLC patients receiving first-line EGFR TKI therapy in Europe.
- Trial name
- REFLECT (NCT04031898)
- Testing
- Non Interventional
- Where
- Bulgaria
- Volunteers
- 896 people
- Sponsor
- AstraZeneca
Breast Feeding, Postpartum Breast Disorders
Nursing Education Intervention for Maternal Breastfeeding
An antenatal education intervention in primiparous women improves breastfeeding duration and reduces post-natal complications.
- Trial name
- NCT02106026
- Testing
- Preventive education
- Volunteers
- 314 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Anxiety, Pain
Comfort Talk for Pediatric Cardiac Catheterization
Background: Pre anaesthesia anxiety in children is a strong predictor of postoperative behavior challenges and outcomes. In addition, intra-operative stress can precipitate post-traumatic stress symptomatology.
- Conditions
- Anxiety, Pain, Adaptation, Psychological, Stress, Psychological
- Trial name
- NCT02347748
- Testing
- Reading pre-procedure script, Reading pre-extubation script, Reading 2 scripts
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- The Hospital for Sick Children
Asthma
Device Mixing in Asthma, a General Practice Research Database Study
This study will compare the absolute and relative effectiveness of asthma management in patients on inhaled corticosteroid (ICS) maintenance therapy as Easi-breathe® (EB) - beclometasone dipropionate (BDP) breath-actuated inhaler…
- Trial name
- EBsalbutamol (NCT01313585)
- Testing
- Initiation of beclometasone via the Easibreathe device plus salbutamol via the Easibreathe device, Initiation of beclometasone via the Easibreathe device plus salbutamol via and MDI device, Increase of beclometasone via the Easibreathe device plus salbutamol via the Easibreathe device
- Where
- United Kingdom
- Volunteers
- 815,377 people
- Sponsor
- Research in Real-Life Ltd
Covid19
Response of Korean Medicine Hospital to COVID-19
The objectives of this study are to report the response strategy to prevent COVID-19 spread implemented at a Korean medicine hospital, and the satisfaction survey results regarding its preventive measures.
- Trial name
- NCT04529447
- Testing
- Survey
- Where
- South Korea
- Volunteers
- 485 people, healthy volunteers welcome
- Sponsor
- Jaseng Hospital of Korean Medicine
Psychological Distress
Practice-Based Evidence in Psychotherapy: A Multicentric Study From Ecuador
The goal of this observational study is to learn about the progress and outcomes of clients receiving psychotherapy for common mental health problems in Ecuador.
- Trial name
- CLIP_Ecuador (NCT07257848)
- Testing
- Psychological Intervention
- Where
- 11 sites in Ecuador
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Universidad de las Americas - Quito
HIV-1-infection, Breastfeeding
Understanding Practices of Lactation and Infant Feeding Together With Women With HIV in the United States
IMPAACT 2046/UPLIFT (Understanding Practices of Lactation and Infant Feeding decisions Together with women with HIV) is a multi-site, mixed-methods, observational cohort study.
- Conditions
- HIV-1-infection, Breastfeeding, Pregnancy Related
- Trial name
- UPLIFT (NCT07293559)
- Testing
- No intervention provided in this study
- Where
- 11 sites in United States
- Volunteers
- 1,150 people, healthy volunteers welcome
- Sponsor
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Bronchiolitis
Utility of Severity Scales in Clinical Practice in Children Hospitalized Due to Bronchiolitis.
Prospective observational study of patients hospitalized with bronchiolitis. The objective of our study is to compare the accuracy of commonly used clinical scales for bronchiolitis to predict relevant outcomes.
- Trial name
- NCT06737159
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Szpital im. Św. Jadwigi Śląskiej
Emergencies
Effect of Covid-19 Pandemic on Emergency Surgery Practice
A retrospective study at a tertiary university hospital to determine the effect of the COVID-19 pandemic on the emergency surgery practice in the hospital.
- Trial name
- NCT04815135
- Testing
- Observational study
- Where
- Jordan
- Volunteers
- 344 people
- Sponsor
- Ibrahim Khrais
Failure to Thrive, Nutritional Deficiency
Nasogastric Tube Securement Comparison Study
This study evaluates the use of tape to secure nasogastric tubes compared to securement with a nasal bridle device.
- Conditions
- Failure to Thrive, Nutritional Deficiency, Constipation, Bowel Obstruction
- Trial name
- NTSNB (NCT03202576)
- Testing
- Nasal Bridle
- Volunteers
- 43 people
- Sponsor
- University of Colorado, Denver
Urinary Tract Infections
Implementation Study With Decision Support Based on Data
This study evaluates the implementation of a machine learning based clinical decision support system for treatment of patients presenting with an urinary tract infection in general practice.
- Trial name
- NCT04408976
- Where
- Netherlands
- Volunteers
- 16,824 people
- Sponsor
- Leiden University Medical Center
Critical Illness, Respiratory Failure
PRactice of VENTilation in Critically Ill PEDiatric Patients
The goal of this worldwide observational study is to investigate ventilation practice in critically ill pediatric patients. The main questions it aims to answer are: 1.
- Trial name
- PRoVent-PED (NCT06220825)
- Where
- Netherlands
- Volunteers
- 2,500 people
- Sponsor
- University Medical Center Groningen
Colorectal Cancer
Translation of Colorectal Cancer Screening Guidelines to Practice: A System Intervention
Colorectal cancer (CRC) is the second leading cause of cancer-related deaths in the United States. Results from randomized clinical trials and intervention studies have suggested that implementation of a CRC screening program for…
- Trial name
- NCT00122187
- Testing
- Electronic Consult System
- Where
- 9 sites in United States
- Volunteers
- 8 people
- Sponsor
- US Department of Veterans Affairs
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