Clinical trials: Prefrontal Cortex
Healthy Participants
Effects of Continuous Theta Burst Stimulation on Emotional Attention
The goal of this clinical trial is to examine the differential effect of continuous TBS (cTBS) over the left and right dorsolateral prefrontal cortex (DLPFC) on the facilitation of attention towards emotional (i.e., pleasant and…
- Trial name
- NCT07268001
- Testing
- Continuous theta burst stimulation
- Where
- Cyprus
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Cyprus
Healthy
Hippocampal and Frontoparietal Development and Inference
The goal of this clinical trial is to test if an intervention used to manipulate memory and inference can improve our understanding of how brain development supports these abilities in healthy adolescent and adult volunteers.
- Trial name
- NCT07199907
- Testing
- Associative Inference, Probabilistic Inference
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Attention Deficit Hyperactivity Disorders
Low-dose vs. Normal-dose Psychostimulants on Executive Functions in Individuals With ADHD
This double-blind crossover study aims to compare cognitive performance (e.g., working memory, selective attention and cognitive flexibility) of children ages 6-18 years diagnosed with ADHD of the combined type (ADHD-C) or…
- Trial name
- NCT02167048
- Testing
- Psychostimulants
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Blindness
Brain Plasticity of Verbal Memory in the Blind
This study will examine whether blind people develop changes in the brain that improve memory function. Previous studies have shown that blind people, on average, perform better in memory tasks than sighted people.
- Trial name
- NCT00059189
- Testing
- Magstim Rapid Magnetic Stimulator
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Developmental Coordination Disorder
Effects of Acute Exercise on Motor Learning and Brain Activity in Children With DCD
The aim of this study is to investigate the impact of an acute intense physical exercise bout on the learning ability of children with typical motor development (TD) and children with developmental coordination disorder (DCD).
- Trial name
- ExLeBrainDCD (NCT05936372)
- Testing
- Acute intense aerobic exercise
- Where
- 3 sites in Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Institut Nacional d'Educacio Fisica de Catalunya
Central Nervous System Disease, Cerebrovascular Accident
Brain Processing of Language Meanings
This research trial will study discourse processing-that is, how the brain processes the meaning of language. It will examine, for example, how words and sentences are interpreted in cases where more than one meaning is possible.
- Conditions
- Central Nervous System Disease, Cerebrovascular Accident, Craniocerebral Trauma, Head Injury
- Trial name
- NCT00005004
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Healthy Children, Preterm Birth
Executive Training and Brain in Children
The purpose of this study is to determine whether a daily executive training to cognitive inhibition, working memory or mindfulness as compared to an active control condition has a near- and far-transfer impact on brain and…
- Trial name
- APEX (NCT02989116)
- Testing
- Inhibition training, Working memory training, Mindfulness training
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Healthy
Magnetic Resonance Imaging of the Brain in Emotional Processing
This study will use magnetic resonance imaging (MRI) to identify brain regions involved in performing certain tasks, especially those involving emotions.
- Trial name
- NCT00061204
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Aggressive Behavior
Brain Changes in Adolescents While Imagining and Observing Aggressive Behavior
This study will use functional magnetic resonance imaging (fMRI) to examine what happens in the brains of adolescents when they are exposed to violent media and how imagining aggressive behavior affects brain function.
- Trial name
- NCT00267891
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Autism Spectrum Disorder
The Therapeutic Effects of Continuous Theta Burst Stimulation in Autism Spectrum Disorder
The investigator would like to investigate the impact of theta burst stimulation over left dorsolateral prefrontal cortex in autism spectrum disorder
- Trial name
- NCT04993144
- Testing
- continuous theta burst stimulation
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Healthy
Brain Encoding for Memory
This two-part study will use transcranial magnetic stimulation, or TMS (see below), to explore how the brain forms memories. People remember only some of the events they experience every day, such as faces they perceive, words…
- Trial name
- NCT00051870
- Testing
- Magstim Rapid Magnetic Stimulator
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Intracranial Central Nervous System Disorder, Mental Disorder
Test of A Model of Representational Knowledge Stored in the Human Prefrontal Cortex
This study will examine the underlying mental processes that determine how people understand social behavior, remember information, and think.
- Conditions
- Intracranial Central Nervous System Disorder, Mental Disorder, Healthy
- Trial name
- NCT00024908
- Where
- United States
- Volunteers
- 949 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Healthy
Magnetic Resonance Imaging of Calculus Problem Solving
This study will use magnetic resonance imaging (MRI) to identify brain regions involved in solving algebraic math problems. It will examine brain activation according to the level of difficulty and the number of steps required to…
- Trial name
- NCT00060658
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Healthy
Positron Emission Tomography Imaging of Dopamine Receptors Using the Tracer [11C]NNC-112
This study will investigate the use of [11C]NNC-112 in positron emission tomography (PET) scanning. PET is a technique that uses radioactive isotopes called tracers to provide images of the brain.
- Trial name
- NCT00088517
- Testing
- [11C]NNC-112
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Major Depressive Disorder, Major Depressive Disorder, Recurrent
Glutamate Probes in Adolescent Depression
The purpose of this study is to learn if measures of brain chemicals from a brain scan called Magnetic Resonance Imaging and Spectroscopy (MRI/MRS) and brain activity (known as cortical excitability and inhibition) collected by…
- Conditions
- Major Depressive Disorder, Major Depressive Disorder, Recurrent, Major Depressive Disorder, Remitted
- Trial name
- GPII (NCT02307617)
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Healthy
Magnetic Resonance Imaging of the Brain in Social and Emotional Reasoning
This study will use magnetic resonance imaging (MRI) to identify brain regions involved in social and emotional reasoning. It will identify differences in brain activity during task performance between people who have a nervous…
- Trial name
- NCT00060853
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)