Clinical trials: Pregnancy Outcome
Neurodevelopmental Disorders, Congenital Heart Disease
Altered Cerebral Growth and Development in Infants With Congenital Heart Disease
Background: Congenital heart disease (CHD) is the most frequent inborn defect with an incidence of 1 in 100 newborns per year, i.e. 800 children born in Switzerland per year.
- Conditions
- Neurodevelopmental Disorders, Congenital Heart Disease, Brain Injuries, Fetal Growth Retardation
- Trial name
- NCT04233775
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Anterior Urethral Stricture, Male
Anatomical and Functional Outcome of PSG Vs BMG for Urethral Substitution in Long Segment Anterior Urethral Strictures
This study aims to compare the penile skin graft and buccal mucosal graft for substitution of long anterior urethral strictures using one-sided dorsal perineal approach.
- Trial name
- NCT06056856
- Testing
- Penile skin graft substituttion urethroplasty, Buccal Mucosal Graft substitution urethroplasty
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Kidney Transplantation
Noninvasive Methods to Monitor Graft Survival in Kidney Transplant Patients
The purpose of this study is to test noninvasive methods to monitor the health and condition of new kidneys in people who have received kidney transplants.
- Trial name
- NCT00308802
- Testing
- Kidney transplantation
- Where
- 9 sites in United States, Canada
- Volunteers
- 280 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Preterm Birth, Early Intervention
Movement Imitation Therapy for Preterm Babies (MIT-PB) - A Pilot Study
Background: Very preterm babies are at high risk for developmental disorders. Prechtl's General Movements (GMs) Assessment is a valuable and reliable tool in infants until three months corrected age for predicting their further…
- Conditions
- Preterm Birth, Early Intervention, General Movements
- Trial name
- NCT07449312
- Testing
- Movement Imitation Therapy for Preterm Babies (MIT-PB), Usual care Physiotherapy
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- University of Zurich
Preeclampsia
Prediction of Adverse Perinatal Outcome for Preeclampsia in Sichuan Province of China
The purpose of this study is to build a model for the prediction of adverse perinatal outcome for preeclampsia in china
- Trial name
- NCT01804751
- Sponsor
- West China Second University Hospital
Nephrotic Syndrome Steroid-Dependent
Efficacy of Anti-CD20 Antibodies (Rituximab Biosimilar) in the Treatment of Childhood Steroid-dependent Nephrotic Syndrome
Anti-CD20 monoclonal antibodies are emerging as the steroid-sparing therapy of choice for nephrotic syndrome. This Randomized Clinical Trial seeks to evaluate whether Rituximab biosimilar maintains drug-free disease remission in…
- Trial name
- NCT04402580
- Testing
- Rituximab Biosimilar, Mycophenolate Mofetil
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto Giannina Gaslini
Acute Kidney Injury
Regional and Long Term Outcomes of Acute Kidney Injury in England From 2000 to 2015 - A National Database Study
Acute kidney injury requiring dialysis (AKI-D) has increased considerably over last 15 years. The national rise in incidence of acute kidney injury has several ramifications in terms of cost to the health services resulting not…
- Trial name
- NCT02675296
- Where
- United Kingdom
- Volunteers
- 54,680 people
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Anemia, Low Birth Weight
Dietary Diversity is Associated With Maternal Anemia and Key Prenatal Outcomes in Ethiopia
Background: Maternal and child under-nutrition is the underlying cause of death for millions across the globe. Anemia during pregnancy is among the leading nutritional disorders with serious short and long term consequences to…
- Conditions
- Anemia, Low Birth Weight, Pre-Term Birth, Still Birth
- Trial name
- NCT02620943
- Where
- Ethiopia
- Volunteers
- 374 people
- Sponsor
- Dilla University
Maternal Mortality, Perinatal Mortality
Evaluation of a Smartphone Application to Reduce Adverse Pregnancy Outcomes in Ethiopia
The purpose of this trial is to determine if the safe delivery smartphone application distributed to health workers in Ethiopia will decrease perinatal mortality and the incidence of postpartum haemorrhage.
- Trial name
- NCT01945931
- Testing
- Safe Delivery Smartphone Application
- Where
- Denmark
- Volunteers
- 3,601 people
- Sponsor
- University of Copenhagen
Zika Virus, Pregnancy Related
ZIKAlliance Pregnant Women Cohort
The aim of this proposal is to evaluate the causal relationship between Zika virus (ZIKV) infections in pregnancy and congenital malformations.
- Trial name
- ZIKAlliancePW (NCT03188731)
- Where
- 14 sites in Bolivia, Brazil and 5 more
- Volunteers
- 3,852 people, healthy volunteers welcome
- Sponsor
- University of Heidelberg Medical Center
Cirrhosis
Study Of Bacterial/Fungal Infections in Hospitalized Patients With Liver Cirrhosis in China
This is a national, investigator-initiated, multicenter, prospective, observational, web-based registry in hospitalized patients with cirrhosis across China.
- Trial name
- SONIC (NCT03676777)
- Where
- 23 sites in China
- Volunteers
- 1,232 people
- Sponsor
- Ruijin Hospital
Labor Pain, Pregnancy Outcomes
The Association Between Epidural Labor Analgesia and Pregnancy Outcomes
Labor analgesia can alleviate intrapartum pain, in the importance of the delivery is very obvious.But some researches think labor analgesia may affect the progress of labor, increase the cesarean section rate.This research adopts…
- Conditions
- Labor Pain, Pregnancy Outcomes, Psychological Disorder
- Trial name
- NCT03381495
- Testing
- Ropivacaine Hydrochloride, Sufentanil
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Deng Dongrui
Maternal Health, Pregnancy Outcomes
Antenatal and Postnatal Care Research Collective - Household Survey (ARCH)
The overarching goal of the ARCH Survey is to establish a prospective longitudinal pregnancy surveillance study in Lusaka, Zambia, to precisely characterize the pregnancy rate and outcomes of women of reproductive age prior to…
- Trial name
- ARCH (NCT05154331)
- Where
- Zambia
- Volunteers
- 5,500 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Asthma
WEUSRTP4850: Phase II: ICS/LABA Use in Pregnancy and Outcomes
Asthma is reported to affect between 3-14% of pregnancies making asthma medicines one of the most commonly used classes of medicines during pregnancy.
- Trial name
- NCT01681979
- Testing
- Fluticasone propionate (with and without concurrent salmeterol)
- Volunteers
- 1 people
- Sponsor
- GlaxoSmithKline
Pregnancy, Malaria in Pregnancy
Improving PRegnancy Outcomes With Intermittent preVEntive Treatment in Africa
This study evaluates the efficacy and safety of monthly intermittent preventive treatment using dihydroartemisinin piperaquine (DP) alone or in combination with azithromycin (AZ) compared to sulphadoxine-pyrimethamine (SP) for…
- Conditions
- Pregnancy, Malaria in Pregnancy, Malaria
- Trial name
- IMPROVE (NCT03208179)
- Testing
- dihydroartemisinin-piperaquine, sulphadoxine-pyrimethamine, dihydroartemisinin-piperaquine plus azithromycin
- Where
- 7 sites in Kenya, Malawi and 1 more
- Volunteers
- 4,680 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
Pregnancy, Epidural Analgesia, Obstetric
Intelligence and Neurodevelopmental Outcome After Prenatal Exposure to Labour Epidural Analgesia: a Sibling Matched Clinical Ambidirectional Cohort Study
In Belgium, labour epidural analgesia (LEA) has been used for decades in the vast majority of vaginal deliveries (up to 83% of deliveries).
- Trial name
- NCT07014956
- Testing
- Labour epidural analgesia
- Where
- Belgium
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Intrauterine Growth Retardation, Low Birth Weight
Effect of Prenatal Nutritional Supplementation on Birth Outcome in Hounde District, Burkina Faso
Low birth weight (LBW; birth weight<2,500g) is the most important determinant of mortality and morbidity in the neonatal period.
- Trial name
- MISAME2 (NCT00909974)
- Testing
- UNIMMAP - multiple micronutrients, Food supplement enriched with multiple micronutrients
- Where
- Burkina Faso
- Volunteers
- 1,302 people
- Sponsor
- Institute of Tropical Medicine, Belgium
Leiden Factor V Deficiency,Preeclampsia, Doppler Examination
Prediction of Outcome in Severe Preeclampsia
this summary studied the predictive values of factor V Leiden mutation , doppler indices , placental pathology to unfavorable fetal and maternal outcomes
- Conditions
- Leiden Factor V Deficiency,Preeclampsia, Doppler Examination, Palental Pathology
- Trial name
- NCT03871764
- Testing
- blood sample , doppler of uterine vessel and placenta
- Volunteers
- 100 people
- Sponsor
- Cairo University
Fetal Growth Retardation
Antenatal Allopurinol in Intrauterine Growth Restriction
Growth retardation in utero may be caused by uteroplacental vascular insufficiency. When Doppler ultrasound studies of the umbilical artery are abnormal pathological intrauterine growth restriction (IUGR) can be diagnosed.
- Trial name
- NCT00346463
- Testing
- Allopurinol
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- UMC Utrecht
Male Infertility, Unexplained Infertility
Impact of Sperm DNA Integrity on In Vitro Cycles
Sperm DNA integrity will be measured via the Toluidine Blue Assay (TBA) for patients undergoing In Vitro Fertilization (IVF); the study will determine correlations, if any, between IVF success and sperm DNA integrity.
- Conditions
- Male Infertility, Unexplained Infertility, Abortion, Habitual
- Trial name
- TBA on IVF (NCT01232465)
- Where
- United States
- Volunteers
- 420 people
- Sponsor
- Northwell Health