Clinical trials: Pregnancy Testing
Preterm, Breastfeeding
Breastfeeding and Bottle Feeding: Impact on Preterm Infants' Physiology and Feeding Performance
The goal of this clinical trial is to evaluate the effect of breastfeeding on the infant's test weight and physiological characteristics (oxygen saturation and heart rate) in preterm infants in the Neonatal Intensive Care Unit…
- Conditions
- Preterm, Breastfeeding, Bottlefeeding, Premature
- Trial name
- NCT05651035
- Testing
- oral feeding
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Malaria, Sexually Transmitted Diseases
Gestational Sulfadoxine-pyrimethamine and Azithromycin Treatment to Prevent Preterm Birth
The purpose of this study is to examine whether treatment of pregnant Malawian women with repeated doses of sulfadoxine-pyrimethamine and azithromycin antibiotics will prevent preterm deliveries and result in other health…
- Conditions
- Malaria, Sexually Transmitted Diseases, Preterm Birth, Pregnancy
- Trial name
- NCT00131235
- Testing
- Sulfadoxine-pyrimethamine treatment twice during pregnancy, Sulfadoxine-pyrimethamine at 4-week intervals, Sulfadoxine-pyrimethamine every 4 weeks + azithromycin twice
- Where
- Malawi
- Volunteers
- 1,320 people, healthy volunteers welcome
- Sponsor
- Tampere University
Sexually Transmitted Infection, HIV/AIDS
Clinical Study of STI Screening to Prevent Adverse Birth and New-born Outcomes (Philani Ndiphile)
This study aims to evaluate different screening strategies to decrease the burden of Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT) and Trichomonas vaginalis (TV) among pregnant women, and reduce adverse birth outcomes.
- Conditions
- Sexually Transmitted Infection, HIV/AIDS, Cost-effectiveness, Birth Outcomes
- Trial name
- NCT04446611
- Testing
- First antenatal care + test-of-cure, First antenatal care + week 30-34 gestation (no test-of-cure)
- Where
- South Africa
- Volunteers
- 2,247 people, healthy volunteers welcome
- Sponsor
- Foundation for Professional Development (Pty) Ltd
Pregnant Women
Verification of Correlation Between Genetic Testing of Nutritional Metabolism and Clinical Biochemical Indicators
The research plan is divided into two parts. The first part is the correlation study .It is planned to include women who prepare for pregnancy or in the early stages of pregnancy to carry out the detection of 25 loci SNP of 21…
- Trial name
- NCT03651934
- Testing
- Normal iron, Weak iron, Normal selenium
- Volunteers
- 600 people
- Sponsor
- Peking Union Medical College Hospital
Methylation, Body Composition
Diet and Nutrition Pilot Study for Chinese Adolescents and Their Mothers
Background: Researchers want to collect information on diet, physical activity, and sun exposure in children and young adults. The data can provide information on the effect these factors might have on the development of cancer…
- Conditions
- Methylation, Body Composition, Physical Activity, Puberty
- Trial name
- NCT01517139
- Where
- China
- Volunteers
- 278 people
- Sponsor
- National Cancer Institute (NCI)
Pharmacogenomic Testing
VICE-MPRINT: Maternal and Pediatric Pharmacogenetics Survey
The field of pharmacogenetics has progressed from the discovery of genetic variants that cause variable function of drug metabolism enzymes to a cornerstone of clinical precision medicine.
- Trial name
- MPRINT (NCT05037305)
- Testing
- Educational video
- Where
- 2 sites in United States
- Volunteers
- 798 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Breast Cancer, Hereditary Breast/Ovarian Cancer (brca1, brca2)
Standard Genetic Counseling With or Without a Decision Guide in Improving Communication Between Mothers Undergoing BRCA1/2 Testing and Their Minor-Age Children
RATIONALE: A study that evaluates the support of a decision guide used together with genetic counseling may improve communication between mothers undergoing BRCA1/2 testing and their minor-age children.
- Trial name
- NCT00685256
- Testing
- counseling intervention, educational intervention, survey administration
- Where
- 2 sites in United States
- Volunteers
- 245 people
- Sponsor
- Georgetown University
Autosomal Dominant Polycystic Kidney Disease (ADPKD
Hypertension in Children and Young People at Risk of Autosomal Dominant Polycystic Kidney Disease
The goal of this project is to measure the prevalence of Autosomal Dominant Polycystic Kidney Disease (ADPKD) and hypertension in the general population of children and young people at risk of ADPKD, using magnetic resonance…
- Trial name
- HIYA-PKD (NCT07260071)
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- King's College London
IUGR, Fetal Growth Retardation
Cardiac Displacement From Third Trimester to Early Childhood
The aim is to increase awareness of the relationship between (IUGR) and cardiac function in the foetus, the development of cardiac function over time after delivery and what significance a possible early disturbed myocardial…
- Conditions
- IUGR, Fetal Growth Retardation, Intrauterine Growth Restriction
- Trial name
- CADETTE (NCT02583763)
- Testing
- Echocardiography, Blood sample
- Where
- 2 sites in Sweden
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Premature Rupture of Membrane
The Use of Quantitative Pregnancy Test in Amniotic Fluid as a Diagnostic Tool for Rupture of Fetal Membranes
Two groups will be recruited. The first group are pregnant ladies that have unequivocal rupture of fetal membranes that is diagnosed by seeing the amniotic fluid leakage in the vagina.
- Trial name
- NCT03106311
- Testing
- assessment of beta subunit of human chorionic gonadotropin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Gestational Diabetes Mellitus
Study of Postprandial Incretin Response in Women With Gestational Diabetes
The researchers investigated nineteen pregnant women in third trimester and again postpartum. At the experimental days we performed a mealtest and drew blood for analyses of glucagon-like peptide-1 (GLP-1), glucose-dependent…
- Trial name
- NCT01274052
- Testing
- Meal test
- Where
- Denmark
- Volunteers
- 19 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Fever Without Source
Impact of a PCT(Procalcitonin) Rapid Test -Based Approach on ATB (Antibiotics) Use in Children With Fever Without Source
Because a newly available point-of-care test may have real interest especially for children in the Emergency Department (ED) setting, by limiting painful and stressful venipunctures and decreasing the length of stay in the ED…
- Trial name
- DIAFEVER (NCT03607162)
- Testing
- DIAFEVER algorithm
- Where
- 26 sites in France, Switzerland
- Volunteers
- 4,928 people
- Sponsor
- Nantes University Hospital
Urinary Bladder, Neurogenic, Urodynamics
Measurement of Bladder Pressure With a Novel External Device, Comparison to Urodynamics Testing
The investigators have developed a novel pressure monitoring device that hooks to standard urinary catheters. The investigators will be testing how the pressure measurements recorded with this device compare to the gold standard…
- Trial name
- NCT03456089
- Testing
- Urodynamics Testing
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Christopher Cooper
Bronchopulmonary Dysplasia
The Role of Volatile Organic Compounds (VOCs), Airway Mucins and the Microbiome in the Early Prediction of Bronchopulmonary Dysplasia (BPD)
Bronchopulmonary dysplasia (BPD), the most common respiratory complication of extremely preterm birth, significantly impacts healthcare with high morbidity and mortality rates.
- Trial name
- INFANCY (NCT06342752)
- Testing
- Breath test, Throat swabs, Placental samples
- Where
- Belgium
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Preeclampsia, Eclampsia
uChek Pilot Study for Urinalysis in the Antenatal Care Setting
A prospective observational study to test the feasibility of smartphone enabled uChek urinalysis device to detect biomarkers (protein, microalbumin and protein:creatine ratio) in urine, indicative of preeclampsia/eclampsia at…
- Conditions
- Preeclampsia, Eclampsia, Pregnancy, Proteinuria
- Trial name
- uChekBangla (NCT02256995)
- Testing
- uChek
- Where
- Bangladesh
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Maternova Research
Smoking Cessation, Pregnancy Related
Effectiveness and Cost-effectiveness of a Tailored Text Message Programme (MiQuit) for Smoking Cessation in Pregnancy
The trial aims to determine whether or not MiQuit (text-message support programme) is effective when offered in addition to standard behavioural support for smoking cessation in pregnancy.
- Trial name
- NCT03231553
- Testing
- MiQuit text message support programme
- Where
- 17 sites in United Kingdom
- Volunteers
- 1,000 people
- Sponsor
- University of Nottingham
HIV Infections, Syphilis Infection
Implementation of an Opt-Out Testing and Rapid Diagnostic Strategy for Syphilis and HIV in Pregnant Patients Presenting to the Emergency Department
The purpose of this study is to evaluate infection detection and treatment initiation rates for syphilis and HIV before and after integration of the Chembio DPP® HIV-Syphilis rapid POC test into an ongoing Emergency Department…
- Trial name
- NCT07525076
- Testing
- Chembio HIV/Syphilis rapid Point of Care (POC) test, Laboratory-based HIV and syphilis testing
- Where
- United States
- Volunteers
- 1,400 people
- Sponsor
- The University of Texas Health Science Center, Houston
Unintended Pregnancy, Family Planning
Efficacy Testing of a Multi-Level Family Planning Intervention
The goal of this cluster randomized controlled trial is to learn if the multi-level, community-based family planning intervention, known as the Family Health=Family Wealth (FH=FW) program, can improve family planning outcomes in…
- Trial name
- NCT06923189
- Testing
- Family Planning Intervention, Water, Sanitation, and Hygiene (WASH) Intervention
- Where
- Uganda
- Volunteers
- 1,464 people, healthy volunteers welcome
- Sponsor
- Boston College
Tobacco Use Cessation, Pregnancy Related
Pilot Trial of Using SmokeBeat to Monitor and Increase Smoking Abstinence in Pregnant Women
Investigators will assess the feasibility of implementing a randomized control trial of a behavioral intervention that uses smartwatch technology to monitor smoking behavior with texts aimed at reducing smoking in pregnant women…
- Trial name
- NCT03209557
- Testing
- SmartWatch SmokeBeat Application
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Preterm Birth Complication, Cerebral Palsy
Validity and Reliability of Specific Test of Early Infant Motor Performance (STEP) Version 3.0
Cerebral palsy and other neuromotor disorders are more common in babies born preterm (<37 weeks of gestation), due to various biological and environmental risk factors and the risk increases as the gestational age decreases.
- Conditions
- Preterm Birth Complication, Cerebral Palsy, Infant, Premature, Diseases
- Trial name
- NCT05624541
- Testing
- Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Marmara University