Clinical trials: Pregnancy Trimester, Second
Labor Induction
Factors Influencing the Abortion Interval of Second-trimester Termination of Pregnancy Using Misoprostol
This study aims to analyze the factors influencing the abortion interval of second-trimester termination of pregnancy using misoprostol.
- Trial name
- NCT01927822
- Where
- Taiwan
- Volunteers
- 101 people
- Sponsor
- Far Eastern Memorial Hospital
Preterm Birth, Pregnancy Trimester, Second
Progesterone for Prevention of Preterm Birth in Women With Short Cervix: Randomized Controlled Trial
The aim of our study is to evaluate the effect of use of prophylactic vaginal progesterone on the incidence of severe preterm delivery, defined as delivery before 33+6 weeks in women with a short cervical length of 15mm.
- Trial name
- NCT00422526
- Testing
- Micronised progesterone (Utrogestan)
- Where
- 8 sites in Brazil, Chile and 2 more
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Multiple Sclerosis (MS)
An Observational Study to Learn About the Interferon-beta Exposure of Pregnant Women During the Second and Third Trimester in Finland and Sweden
Observational data have suggested no increased risk of adverse pregnancy outcomes associated with exposure to interferon-beta (IFNB) before or during pregnancy.
- Trial name
- INFORM (NCT06053749)
- Testing
- Avonex (IFNβ-1-a, Biogen Netherlands B.V), Rebif (IFNβ-1-a, Merck Europe B.V.), Extavia (IFNβ-1-b, Novartis Europharm Limited)
- Where
- 2 sites in Finland, Sweden
- Volunteers
- 4 people
- Sponsor
- Bayer
Pre-Eclampsia
Predictors of Intrauterine Growth Restriction
The main objectives of modern antenatal care programs are to identify high risk pregnancies then to predict any possibility of adverse pregnancy outcome as early as possible.
- Trial name
- NCT03349671
- Testing
- ultrasound
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Assiut University
Pain Alleviation, Dilatation and Evacuation
Use of Nitrous Oxide for Pain Alleviation in Women Undergoing Osmotic Dilator Insertion for Dilatation and Evacuation
A randomised control study aiming to examine whether inhaled N2O/O2 during cervical preparation for second trimester dilatation and evacuation with osmotic dilators (laminaria) alleviates pain and is superior to placebo.
- Conditions
- Pain Alleviation, Dilatation and Evacuation, Laminaria Placement, Nitrous Oxide
- Trial name
- NCT05579288
- Testing
- Nitrous oxide (N2O/O2), Oxygen (O2)
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Abortion in Second Trimester
Mifepristone and Misoprostol for Midtrimester Termination of Pregnancy in Uzbekistan
The primary goal is to examine the efficacy and feasibility of a mifepristone-misoprostol medical abortion regimen in terminating pregnancies 13-22 weeks in Uzbekistan.
- Trial name
- NCT02235155
- Where
- 3 sites in Uzbekistan
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Labor Induction
A Randomized Trial of Two Regimens of Misoprostol for Second Trimester Termination for Intrauterine Fetal Death
Misoprostol (Cytotec®) is a synthetic prostaglandin E1 analog that has been marketed in the United States since 1988 as a gastric cytoprotective agent.
- Trial name
- NCT00141895
- Testing
- Misoprostol
- Where
- Lebanon
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Down Syndrome, Chromosome Abnormalities
Down Syndrome - Comparison of Screening Methods in the 1st and 2nd Trimesters
Too much or too little genetic information (chromosome material) can cause abnormal development of the fetus or death. Each year approximately 2.5 million pregnant women are screened for Down Syndrome using invasive screening…
- Trial name
- NCT00006445
- Testing
- Ultrasound, Serum screen
- Where
- 10 sites in United States
- Volunteers
- 38,000 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Congenital Heart Defects
Use of Color Doppler in Routine Examination of Fetal Heart in Second Trimester
To evaluate the percentage of severe heart defect diagnosed with the use of color Doppler at a routine fetal scan in the second trimester of pregnancy
- Trial name
- NCT01201486
- Where
- Norway
- Volunteers
- 6,781 people
- Sponsor
- Helse Stavanger HF
Induction of Second Trimester Abortion
Use of Ulipristal Acetate in Induction of Second Trimester Missed Abortion
The aim of this work is to assess the effectiveness and safety of Ulipristal Acetate in the management of 2nd trimester missed abortion along with misoprostol in pregnant women with previous caesarean section versus the use of…
- Trial name
- NCT04989400
- Testing
- Ulipristal Acetate, Misoprostol
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Abortion, Induced
Mifepristone and Misoprostol Versus Misoprostol Alone for Mid-trimester Termination of Pregnancy (14 - 21 Weeks LMP): A Randomized-controlled Double-blinded Trial
The primary goal of this study is to determine the clinical advantage of pre-treatment with mifepristone in second trimester misoprostol induction abortion.
- Trial name
- NCT00784186
- Testing
- mifepristone+misoprostol, misoprostol
- Where
- 2 sites in Vietnam
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Placenta, Retained, Postpartum Hemorrhage
Optimisation of the Management of Placental Delivery in Second Trimester Pregnancy Interruption
Interruption of a pregnancy after 14 weeks gestation may be required when the fetus is dead, severely malformed or in cases of maternal illness.
- Trial name
- NCT00120042
- Testing
- Misoprostol, Oxytocin
- Where
- Australia
- Volunteers
- 251 people
- Sponsor
- The University of Western Australia
Pregnancy Related
Effects of Snakehead Fish on IUGR and LBW Among Second and Third Trimester Women
This study uses a Randomized Controlled Trial (RCT) design, conducted on pregnant women in Yogyakarta Province, Indonesia. This study aims to observe the effects of snakehead fish prepared-meal intervention on fetal growth…
- Trial name
- NCT07005609
- Testing
- Snakehead fish meal
- Where
- Indonesia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Gadjah Mada University
Induced Abortion
Comparison of Two Regimens of Misoprostol for Second Trimester Medical Termination of Pregnancy
The hypothesis of the study is that the induction abortion interval time will be significantly shorter in the group receiving vaginal misoprostol every six hours in comparison to the group who are receiving vaginal misoprostol…
- Trial name
- NCT00401440
- Testing
- Misoprostol
- Where
- India
- Volunteers
- 185 people
- Sponsor
- Nilratan Sircar Medical College
Abortion, Induced
Mifepristone and Misoprostol Versus Misoprostol Alone for Mid-trimester Termination of Pregnancy (14-21 Weeks LMP)
The primary goal of this study is to determine the clinical advantage of pre-treatment with mifepristone in second trimester misoprostol induction abortion.
- Trial name
- NCT00957346
- Testing
- Mifepristone+misoprostol
- Where
- Puerto Rico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Uterine Artery Flow
Uterine Artery Doppler Changes
In uncomplicated pregnancies, the uterine spiral arteries undergo a series of structural changes that result in a low resistance in the uterine arteries as pregnancy progresses.
- Trial name
- NCT03064698
- Testing
- Post-partum Doppler ultrasound
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Placenta Previa Complete Centralis
Accuracy of Rail Sign at Detection of PAS
Accuracy OF Rail Sign at Detection Of Placenta Accreta At The second And the Third Trimester Of Pregnancy By Ultrasound Scanning
- Trial name
- NCT07159997
- Testing
- Accuracy of rail sign by ultrasound st diagnosis placent previa
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Sohag University
Abortion, Induced, Labor Stage, Third/Drug Effects
Oxytocin Infusion vs. Spontaneous Follow-up for Third-stage of Labor After Second-trimester Abortion
This study compares oxytocin infusion to spontaneous follow-up for third-stage of labor at induced mid-trimester abortions. Patients will be randomized to oxytocin infusion or observation with no pharmacologic intervention.
- Conditions
- Abortion, Induced, Labor Stage, Third/Drug Effects, Pregnancy Trimester, Second, Oxytocin/Administration & Dosage
- Trial name
- NCT02485444
- Testing
- Oxytocin
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Ataturk University
Abortion, Induced, Abortion, Second Trimester
Mifepristone and Mid-Trimester Termination of Pregnancy
Mid-second trimester medical terminations of pregnancy require admission to the hospital for the length of time it takes a woman to abort.
- Trial name
- NCT00382538
- Testing
- Addition of mifepristone 200 mg 24 hours before induction
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Boston University
Second Trimester Abortion
Second Trimester Pregnancy Termination in Women With Previous Caesarean Sections
it is a randomized controlled trial comparing the safety and efficacy of Vaginal Misoprostol versus combined Intracervical Foley's Catheter and Oxytocin Infusion for Second Trimester Pregnancy Termination.
- Trial name
- NCT04501809
- Testing
- compare misoprostol with combined oxytocin and cervical foly catheter
- Where
- 2 sites in Egypt
- Volunteers
- 158 people
- Sponsor
- Zagazig University