Clinical trials: Premedication
Respiratory Distress Syndrome
Premedication for Non-Emergency Endotracheal Intubation In the NICU
Those infants who received the muscle relaxation in combination with the vagolytic (reduce vagus nerve impulses) and pain medication will have reduced time to successful intubation (placement of tube into the lungs), a decrease…
- Trial name
- NCT01749501
- Testing
- Rocuronium
- Volunteers
- 45 people
- Sponsor
- Martin Espinosa, MD
Lactium, Premedication
Lactium Premedication to Prevent Emergence Agitation
This biased coin sequential allocation, dose finding study will be conducted to determine the effective dose of oral lactium in 90% of children (ED90) for prevention of emergence agitation during recovery from adenotonsillectomy.
- Conditions
- Lactium, Premedication, Emergence Agitation, Adenotonsillectomy
- Trial name
- NCT07894484
- Testing
- Lactium
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Dexmedetomidine, Adenotonsillectomy
Nebulized Dexmedetomidine, Ketamine, or Midazolam in Children Undergoing Adenotonsillectomy
The aim of this study is to compare between nebulized dexmedetomidine, ketamine, or midazolam for premedication in children undergoing adenotonsillectomy.
- Conditions
- Dexmedetomidine, Adenotonsillectomy, Midazolam, Children
- Trial name
- NCT07564037
- Testing
- Group K:nebulized ketamine group, Group D:dexmedetomidine group, Group M: midazolam group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Postoperative Respiratory Complication
Nebulized Lidocaine vs 3% Sodium Chloride in Pediatric Adenoid/Tonsil Surgery
This prospective, randomized clinical trial aims to evaluate the effect of preoperative nebulized lidocaine and nebulized 3% hypertonic sodium chloride (NaCl) on the incidence of postoperative respiratory complications in…
- Trial name
- NCT07267897
- Testing
- Nebulize Lidocaine, Nebulize %3 Sodium Chloride
- Volunteers
- 90 people
- Sponsor
- Sakarya University
Oncological Children
Premedication With Nebulized Ketamine,Dexmedetomidine Versus Midazolam in Oncologic Preschool Children
Evaluate the efficacy of nebulized dexmedetomidine, nebulized ketamine, and nebulized midazolam a premedication prior to general anesthesia (GA) in oncologic preschool children undergo bone marrow aspirate and biopsy.
- Trial name
- NCT02935959
- Testing
- nebulized ketamine, nebulized Dexmedetomidine, nebulized midazolam
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Inhalational Anesthetics Adverse Reaction, Delirium on Emergence
Effects of Dexmedetomidine Premedication on Emergence Agitation After Strabismus Surgery in Children
Sevoflurane is frequently used for pediatric anesthesia because it has low pungency and rapid onset and offset of action.The reported incidence of emergence agitation (EA) following sevoflurane anesthesia varies from 10-80%.
- Conditions
- Inhalational Anesthetics Adverse Reaction, Delirium on Emergence, Strabismus Following Ocular Surgery
- Trial name
- NCT01895023
- Testing
- Dexmedetomidine, Midazolam, Saline
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Yao Yusheng
Asthma
Pharmacological Modulations of Allergen-Specific Immunotherapy
There is mounting evidence that successful allergen immunotherapy (SIT) functions through the induction of different subset of Treg including Foxp3 positive cells, therefore additional strategies to enhance this property are…
- Trial name
- NCT00504946
- Testing
- prednisone, lactose, prednisone, colecalciferol, lactose, lactose
- Where
- Poland
- Volunteers
- 85 people
- Sponsor
- Medical University of Lodz
Tonsillectomy, Adenoidectomy
Effect of Intranasal Midazolam Versus Ketamine Midazolam Combination as a Premedication on the Occurrence of Postoperative Respiratory Adverse Events
The aim of this study is to investigate the effect of addition of intranasal ketamine to midazolam compared to midazolam alone as a premedication on the occurrence of PRAEs
- Conditions
- Tonsillectomy, Adenoidectomy, Drug-Related Side Effects and Adverse Reaction
- Trial name
- NCT06122948
- Testing
- The midazolam group, The midazolam ketamine group
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Kasr El Aini Hospital
Pediatric Anesthesia, Preoperative Anxiety
Intranasal Dexmedetomidine vs Oral Midazolam for Premedication in Pediatric Surgery
This study aims to compare the effects of intranasal dexmedetomidine and oral midazolam as premedication in pediatric patients undergoing elective inguinal and urological surgery under general anesthesia.
- Conditions
- Pediatric Anesthesia, Preoperative Anxiety, Emergence Agitation
- Trial name
- NCT07565116
- Testing
- Dexmedetomidine, Midazolam
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Anesthesia
Effect of Oral Dexmedetomidine, Ketamine, Or Midazolam as Preioperative Medications.
Anxiety preceding surgery results in hemodynamic instability, metabolic side effects, increased post-operative pain, and agitation during emergence.
- Trial name
- NCT05874245
- Testing
- oral Dexmedetomidine, oral ketamine, oral Midazolam
- Where
- Egypt
- Volunteers
- 222 people
- Sponsor
- Menoufia University
Neonatal Respiratory Distress
Study of PREMEdication Before Laryngoscopy in Neonates in France
This study is a national prospective survey on practices of premedication before laryngoscopy in neonates. The survey will evaluate adequation to the French best practice guidelines to improve their dissemination and to identify…
- Trial name
- SUPREMEneo (NCT06356909)
- Testing
- Survey of sedo-analgesia practices before laryngoscopy
- Where
- France
- Volunteers
- 741 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil