Clinical trials: Prenatal; Postnatal
Neonatal Abstinence Syndrome
Non-Opiate Treatment After Prenatal Opiate Exposure to Prevent Postnatal Injury to the Young Brain
The long term goals of our research are to establish the best pharmacological treatment for NAS and determine how pharmacologic treatment of NAS affects long-term developmental outcomes.
- Trial name
- No-POPPY (NCT03396588)
- Testing
- Clonidine, Morphine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Henrietta Bada
Vitamin D Deficiency, Osteoporosis
Does Vitamin D Alter Bone's Response to Vibration?
Fractures in children are common and the incidence is increasing. They are more common in children who have small, narrow and weak bones.
- Trial name
- NCT02743559
- Testing
- Mechanical Stimulation using whole body vibration
- Where
- United Kingdom
- Sponsor
- Sheffield Children's NHS Foundation Trust
Supportive Care
The Effect of Transtheoretical Model-Based Motivational Interviewing on Postpartum Contraception
The goal of this clinical trial is to evaluate the effect of transtheoretical model-based antenatal and postnatal motivational interviewing on contraceptive self-efficacy, contraceptive attitude, and postpartum contraception use.
- Trial name
- NCT06521138
- Testing
- Motivational interviewing group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Gazi University
Hygiene
Reducing Visitors- and Personnel-associated Infection Risk on Perinatal Care Station
The rate of infectious diseases (amnioninfection syndrome (AIS), fetal inflammatory response syndrome (FIRS), early-onset neonatal sepsis (EONS)) in perinatal care / neonatology is steadily rising in Germany.
- Trial name
- NCT03032887
- Testing
- voice prompts, agitation
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
High Perinatal Mortality, High Neonatal Mortality
Measuring the Impact of a Mobile Health System to Support Healthy Pregnancies and Improve Newborn Survival
The purpose of this community-based randomized controlled trial is to test whether the mCARE-II intervention package, delivered by the existing Government of Bangladesh community health workforce, will improve neonatal and…
- Conditions
- High Perinatal Mortality, High Neonatal Mortality, Low Antenatal Care Service Utilization, Low Postnatal Care Service Utilization
- Trial name
- mCARE-II (NCT02909179)
- Testing
- mCARE-II
- Where
- Bangladesh
- Volunteers
- 113,539 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Fetal Alcohol Spectrum Disorders, Fetal Alcohol Syndrome
Postnatal Choline Supplementation in Children With Prenatal Alcohol Exposure
The purpose of this study is to determine if choline bitartrate can be administered daily to children with prenatal alcohol exposure, ages 2.5 to 5, as a potential treatment for brain development and cognitive functioning.
- Conditions
- Fetal Alcohol Spectrum Disorders, Fetal Alcohol Syndrome, Partial Fetal Alcohol Syndrome, Alcohol Related Neurodevelopmental Disorder
- Trial name
- NCT01149538
- Testing
- Choline bitartrate
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Minnesota
Metabolic Disease, Neurological and Mental Health Conditions
Singapore PREconception Study of Long-Term Maternal and Child Outcomes
We aim to test the following primary hypothesis that nutrition, lifestyle, and maternal emotional health prior to pregnancy and/or during the first trimester alter the expression of metabolic or neurodevelopmental endophenotypes…
- Conditions
- Metabolic Disease, Neurological and Mental Health Conditions, Genetics Predisposition, Skin Condition
- Trial name
- S-PRESTO (NCT03531658)
- Where
- Singapore
- Volunteers
- 1,054 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Anorectal Malformations
Study of Antenatal and Postnatal Data of Anorectal Malformations Diagnosed at Montpellier University Hospital Over a 10-year Period (2010-2020)
Objective : Anorectal malformations (ARMs) are part of a spectrum of malformations due to an abnormal separation between the urogenital and digestive tracts during embryonic life.
- Trial name
- NCT05045560
- Where
- France
- Volunteers
- 98 people
- Sponsor
- University Hospital, Montpellier
Intestinal Obstruction
Neonatal Intestinal Obstruction: Prenatal Factors and Postnatal Outcomes
Neonatal intestinal obstruction is one of the most common surgical emergencies in newborns. In some cases, signs of possible intestinal obstruction can already be detected during pregnancy through prenatal ultrasound.
- Trial name
- OIN (NCT07434596)
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Meyer Children's Hospital IRCCS
Congenital Heart Disease, Coarctation of Aorta
An Integrated Prenatal and Postnatal Treatment Model for the Treatment of Newborns With Critical Congenital Heart Disease
The purpose of this two-way cohort study was to explore whether an integrated prenatal and postnatal treatment model for neonates with critical congenital heart disease (CCHD) could be effective in avoiding preoperative…
- Conditions
- Congenital Heart Disease, Coarctation of Aorta, Aortic Stenosis, Pulmonary Atresia
- Trial name
- NCT06768008
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Beijing Anzhen Hospital
Prenatal; Postnatal
Navigation Study: Durham
The purpose of this RCT is to evaluate the implementation and impact of a new, community-wide prevention program, "Community Navigation", on maternal and child health and well-being.
- Trial name
- NCT04438031
- Testing
- Navigation Intervention Version 1.0 (discontinued, modified to Version 2.0. Data will not be used), Control Intervention, Navigation Intervention Version 2.0
- Where
- United States
- Volunteers
- 815 people
- Sponsor
- Duke University
Prematurity Complications, Neurodevelopment Outcome
Antenatal vs Postnatal Transport Team Positioning in Extremely Preterm Outborn Infants
The extremely preterm outborn births (delivered in maternity units without on-site neonatal intensive care) are associated with lower survival and increased risk of severe neurodevelopmental impairment compared with inborn births…
- Conditions
- Prematurity Complications, Neurodevelopment Outcome, Prematurity
- Trial name
- OutbornTRANSF (NCT07580859)
- Testing
- Usual Care
- Where
- France
- Volunteers
- 627 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Maternal Mortality, Maternal Morbidity
An Implementation Study of Interventions to Promote Safe Motherhood in Jimma Zone Ethiopia
Ethiopia has one of the highest rates of maternal mortality among all countries in Africa and indeed worldwide, with a maternal mortality ratio of 676 per 100,000 live births in 2011 (UNFPA, 2012).
- Trial name
- NCT03299491
- Testing
- MWA intervention, IEC intervention
- Volunteers
- 3,784 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Prematurity of Fetus, Postnatal Growth Disorder
Early Versus Late Initiation of Feeding in Premature Growth Restricted Newborns With Absent or Reversed End Diastolic Flow On Umbilical Artery Doppler (AREDF)
The purpose of the study is to compare early versus late initiation of enteral feeding in premature growth restricted babies below the gestational age of 35 weeks born to mothers with prenatal absent or reversal of end diastolic…
- Trial name
- AREDF (NCT01367015)
- Testing
- Early Feeding, Late Feeding
- Where
- India
- Volunteers
- 60 people
- Sponsor
- All India Institute of Medical Sciences
Prenatal Community Program, Vulnerable Population
Parkdale Infant Nutrition Security Targeted Evaluation Project: Chart Review
In Toronto Ontario, the Parkdale Community Health Centre operates a community outreach program entitled Parkdale Parents' Primary Prevention Project (5P's).
- Conditions
- Prenatal Community Program, Vulnerable Population, Postnatal Community Program
- Trial name
- PINSTEP-1 (NCT03372408)
- Testing
- Chart review
- Where
- Canada
- Volunteers
- 338 people
- Sponsor
- University of Toronto
Pregnancy Complications, Preterm Birth
Group Antenatal/Postnatal Care in Rwanda
The focus of this work is to improve antenatal care (ANC) and postnatal care (PNC) at the health center level in five districts in Rwanda (Bugesera, Burera, Nyamasheke, Nyarugenge, and Rubavu).
- Conditions
- Pregnancy Complications, Preterm Birth, Preterm Labor, Stillbirth
- Trial name
- PTBi Rwanda (NCT03154177)
- Testing
- Group ANC/PNC, Ultrasound+Pregnancy Testing
- Where
- 2 sites in Rwanda
- Volunteers
- 26,381 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Fear of Childbirth, Pregnancy
Fear of Childbirth - Comparison of Two Treatments
Childbirth related fear is a public health issue strongly related to subsequent reproduction, a request for caesarean section and women's and children's health.
- Trial name
- NCT02306434
- Testing
- Therapy by iCBT, Standard care-counselling
- Where
- Sweden
- Volunteers
- 258 people
- Sponsor
- Uppsala University
Myelomeningocele
Prenatal and Postnatal Ultrasonographic Evaluation of Myelomeningocele to Predict Post-Surgical Outcomes
Myelomeningocele (MMC), also known as open spina bifida, is a serious congenital condition in which the cord and meninges protrude through the spinal column's defective bony encasement due to a defective closure of the posterior…
- Trial name
- NCT07048691
- Testing
- G.E HEALTHCARE ultrasound machine with high-resolution convex probe
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Superior University
HIV Infections, Pregnancy Complications, Infectious
Prenatal and Postnatal Studies of Interventions for Prevention of Mother-To-Child Transmission
The purpose of this study is to collect and study clinical and laboratory information about a pregnant or new mother and her medical care that will increase our knowledge of the best care for HIV-infected pregnant women and their…
- Trial name
- NCT00028145
- Testing
- Adherence assessment
- Where
- 77 sites in United States, Puerto Rico
- Volunteers
- 3,090 people
- Sponsor
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Newborn Health, Multiple Micronutrient Deficiencies During Pregnancy
The MOM-CARE Trial : Evaluating Antenatal and Postnatal MMSPlus for Improved Infant Birth and Growth Outcomes
This clinical trial aims to learn if MMS Plus improves infant health compared to standard MMS during pregnancy and the postnatal period in women living in peri-urban areas of Karachi, Pakistan.
- Conditions
- Newborn Health, Multiple Micronutrient Deficiencies During Pregnancy, Nutrition During Pregnancy, Adaptive Trial
- Trial name
- MOM-CARE (NCT07029282)
- Testing
- MMS, MMS Plus, IFA
- Where
- Pakistan
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University