Clinical trials: Preterm
Ventilation
Haemodynamic Changes With Different Noninvasive Respiratory Modes for Primary Respiratory Support in Preterm Neonates
to evaluate the efficacy of Nasal high frequency oscillatory ventilation (NHFOV) and Vapotherm in comparison to nasal Continuous positive airway pressure (CPAP) as a primary noninvasive respiratory support in preterm neonates
- Trial name
- RDS (NCT06737003)
- Testing
- Nasal high frequency oscillatory ventilation, Vapotherm Group, Nasal CPAP Group
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Premature Birth
Human Milk Fortifier - Growth Evaluation
It it is hypothesized that the growth of preterm infants receiving a new human milk fortifier will be equal or superior to the growth of preterm infants receiving a currently marketed human milk fortifier with a lower protein…
- Trial name
- NCT01771588
- Testing
- Human milk fortifier
- Where
- 11 sites in Belgium, France and 3 more
- Volunteers
- 186 people
- Sponsor
- Société des Produits Nestlé (SPN)
Retinopathy of Prematurity
The Incidence of Treatment-requiring Retinopathy of Prematurity in Greece
A prospective observational study of the incidence of treatment-requiring ROP (TR-ROP), at a national level, in Greece.
- Trial name
- GR-ROP (NCT05099588)
- Testing
- Other: observational study
- Where
- Greece
- Volunteers
- 43 people
- Sponsor
- Aristotle University Of Thessaloniki
Osteopenia Prematurity
Effect of Assisted Exercise on Musculoskeletal System and Growth in Preterm Infants
The primary aim of this study is to assess whether physical activity programs in preterm infants improve bone mineralization as well as growth and reduce the risk of fractures.
- Trial name
- NCT03354988
- Testing
- Physical exercise group, Control group
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Premature Birth
Family Nurture Intervention in the CHoNJ NICU
The purpose of this proposal is to conduct a replication study of Family Nurture Intervention (FNI) at CHoNJ. FNI facilitates mother-infant interactions that are vital to early development.
- Trial name
- NCT02352142
- Testing
- Full Term EEG, Facilitated Infant Care
- Where
- 2 sites in United States
- Volunteers
- 54 people
- Sponsor
- Columbia University
Infection, Bacterial, Infection Prevention
Optimising Kangaroo Care to Reduce Neonatal Severe Infection/Sepsis and Resistant Bacterial Colonisation Among High-risk Infants in NICU.
NeoDeco is a pragmatic, multicenter, parallel-group, cluster-randomised hybrid effectiveness-implementation trial designed to evaluate the impact of implementing optimised Kangaroo Care (KC) at the unit level compared to standard…
- Trial name
- NeoDeco (NCT05993442)
- Testing
- Optimised kangaroo care
- Where
- 24 sites in Greece, Italy and 3 more
- Volunteers
- 3,080 people
- Sponsor
- PENTA Foundation
Infant, Premature
Nasogastric Tube in Premature Babies - Pain and Treatment
Does sucrose or pacifier influence pain in premature babies when a nasogastric tube is inserted?
- Trial name
- NCT00218946
- Testing
- Sucrose, Pacifier, sterile water
- Where
- Norway
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Immature Infant, Essential Fatty Acid Deficiency
Nutrition Therapy in the Immature Infant (ImNuT)
The primary objective of this double-blind randomized study is to assess the effects of an early, enhanced supply of the essential fatty acids (FAs) arachidonic acid (ARA) and docosahexaenoic acid (DHA) on brain maturation…
- Trial name
- ImNuT (NCT03555019)
- Testing
- Formulaid, MCT-oil
- Where
- Norway
- Volunteers
- 121 people
- Sponsor
- Oslo University Hospital
Ultrasound, Newborn Infant
Ultrasound Imaging of Subarachnoidal Space in Newborn Infants
Based on the ultrasound measurement of CSF/spinal cord ratio in neonates the investigators plan to define a normal range of CSF volume for 0-7 day old newborns.
- Trial name
- NCT04004130
- Testing
- Ultrasound imaging
- Where
- Hungary
- Volunteers
- 2,000 people
- Sponsor
- Szeged University
Prolonged Apnea, Prolonged Bradycardia
DTaP and Apnea/Bradycardia in Preterm Infants
The purpose of this study is to examine the relationship between receipt of DTaP and the occurrence of prolonged episodes of apnea and bradycardia in preterm infants, while employing a random control study design and an objective…
- Trial name
- PIA (NCT00482781)
- Testing
- Infanrix, Pediatrix
- Where
- 10 sites in United States
- Volunteers
- 191 people
- Sponsor
- American SIDS Institute
Feeding Intolerance in Preterm, NEC
Non-Invasive Prediction of Necrotizing Enterocolitis in Preterm Neonates with Feeding Intolerance Using Fecal Lipocalin-2 and Electrical Cardiometry
Prospective observational study to evaluate the efficiency of using electrical cardiometry in combination with fecal lipocalin-2 for prediction of NEC in preterm neonates with feeding intolerance
- Conditions
- Feeding Intolerance in Preterm, NEC, Electrical Cardiometry, PreTerm Neonate
- Trial name
- NCT06874153
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Ain Shams University
Breastfeeding, Exclusive, Breastfeeding
Donor Breast Milk and Breastfeeding Rates
The purpose of this pilot study is to determine if a randomized controlled study comparing a human milk diet versus a formula supplemented diet in late preterm and term infants in the neonatal intensive care unit (NICU) is…
- Trial name
- NCT04572581
- Testing
- Donor Breast Milk
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- University of California, Los Angeles
Infant Growth, Mothers' Parental Competence
Nursing and Nurturing Premature Infants
The purpose of this study is to determine whether systematic use of the Newborn Individualized Developmental Care Assessment Program (NIDCAP®) improves the neurologic development of children and the parental competence of mothers.
- Trial name
- NCT00388141
- Testing
- NIDCAP
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- University of Aarhus
Infant, Extremely Premature, Brain Injuries
Safeguarding the Brain of Our Smallest Infants Phase III
the SafeBoosC-III trial investigates the benefit and harms of treatment based on near-infrared spectroscopy monitoring compared with treatment as usual.
- Conditions
- Infant, Extremely Premature, Brain Injuries, Death, Brain, Death; Neonatal
- Trial name
- SafeBoosC (NCT03770741)
- Testing
- Modify cardio-respiratory support to avoid cerebral hypoxia, Treatment as usual
- Where
- Denmark
- Volunteers
- 1,601 people
- Sponsor
- Gorm Greisen
Immune System Diseases, Premature Infant Disease
Oral Colostrum and Its Effect on Immune System
The purpose of this project is to increase the serum immunological defenses of premature infants less then 32 weeks of gestation by administrating colostrum in the oropharyngeal mucosa versus placebo
- Conditions
- Immune System Diseases, Premature Infant Disease, Immunoglobulin Deficiency
- Trial name
- NCT03578341
- Testing
- Orally Colostrum
- Where
- 2 sites in Mexico
- Volunteers
- 96 people
- Sponsor
- Instituto Nacional de Perinatologia Isidro Espinosa de los Reyes
Feeding Intolerance
Preterm Neonatal Feeding Protocol Comparing Feed Administration Time
Doctors have tried many different methods of feeding to try to decrease feeding intolerance in preterm babies so that they spend less time receiving liquid nutrition and have fewer problems with feeding intolerance.
- Trial name
- NCT00997854
- Testing
- Length of time for feed administration
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Respiratory Distress Syndrome in Premature Infants
Stress Assessment With and Without Analgesia During Surfactant Therapy in Preterm Infants.
This study will compare stress, changes in oxygenation and oxidative damage in preterm infants with respiratory distress syndrome (RDS) randomized to receive or not remifentanil as an analgesic drug during the administration of…
- Trial name
- NCT04073173
- Testing
- INSURE, LISA, Analgesic, Opioid
- Volunteers
- 80 people
- Sponsor
- Virgilio Paolo Carnielli
Intraventricular Hemorrhage of Prematurity
Erythropoietin for the Repair of Cerebral Injury in Very Preterm Infants
The purpose of this randomized and placebo-controlled EpoRepair trial is to evaluate the effect of intravenously administered recombinant human erythropoietin (Epo) as compared to placebo in preterm infants with brain damage on…
- Trial name
- EpoRepair (NCT02076373)
- Testing
- recombinant human Erythropoietin
- Where
- 8 sites in Austria, Switzerland
- Volunteers
- 120 people
- Sponsor
- University of Zurich
Episodic Hypoxemia in Mechanically Ventilated Preterm Infants
Volume Guarantee Ventilation in Preterm Infants With Frequent Episodes of Hypoxemia
Preterm infants undergoing mechanical ventilation often present with respiratory instability which leads to fluctuations in ventilation and oxygenation.
- Trial name
- NCT01727505
- Testing
- Sequence A: Conventional-Volume Guarantee, Sequence B: Volume Guarantee-Conventional
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Miami
Acute Kidney Injury, Chronic Kidney Disease
Outcomes of Neonatal Acute Kidney Injury In Premature Infants
The objective of this protocol is to investigate the impact of prematurity, with or without associated acute kidney injury (AKI), on the future risk of chronic kidney disease (CKD) by establishing a patient registry and…
- Trial name
- NCT02375854
- Testing
- Observation
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.