Clinical trials: Preterm Neonates
Bronchopulmonary Dysplasia, Respiratory Tract Infections
Long-term Safety and Efficacy Follow-up Study of PNEUMOSTEM® in Patients Who Completed PNEUMOSTEM® Phase-I Study
This is a 5-year long-term follow-up study of open label, single-center, phase I clinical trial to evaluate the safety and efficacy of PNEUMOSTEM® in premature infants with bronchopulmonary dysplasia.
- Conditions
- Bronchopulmonary Dysplasia, Respiratory Tract Infections, Premature Birth of Newborn
- Trial name
- NCT02023788
- Testing
- PNEUMOSTEM
- Where
- South Korea
- Volunteers
- 8 people
- Sponsor
- Medipost Co Ltd.
Fertility Disorders, Turner Syndrome
The Danish TURNER Cryopreservation Study
The goal of this clinical trial is to investigate if cryopreservation of ovarian tissue in girls with Turner syndrome can improve their fertility and lead to increased number of liveborn babies of Turner syndrome mothers.
- Conditions
- Fertility Disorders, Turner Syndrome, Premature Ovarian Failure
- Trial name
- DANTE (NCT05740579)
- Testing
- laparoscopic cryopreservation of one ovary
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Motor Development, Infant, Premature, Diseases
Peabody Developmental Motor Scale-2 in 0 - 24 Months in Turkey
This study is the determination of the Turkish version of the Peabody Developmental Motor Scale-2 and its Turkish validity reliability in infants age between 0 - 24 months and to spread its use for evaluation in early…
- Trial name
- NCT04886310
- Testing
- Peabody Developmental Motor Scale II (PDMS-2)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ondokuz Mayıs University
Bronchopulmonary Dysplasia
Neonatal Intensive Care (NICU) Course and Hospital Outcome of Infants With BPD Treated Using Inhaled Nitric Oxide
This is a chart review study of neonates admitted to Primary Children's Medical Center or University of Utah NICU who had or developed a diagnosis of bronchopulmonary dysplasia (BPD) and were treated for this condition with…
- Trial name
- NCT00757146
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Utah
Intubation Complication, PreTerm Birth
NIPPV Versus Bi-level Nasal Continuous Positive Airway Pressure Following Extubation
Mechanical ventilation is important in the care of preterm infants with respiratory failure, but may be associated with lung injury. Efforts are needed to avoid or minimize the use of mechanical ventilation.
- Trial name
- NCT02842190
- Testing
- NIPPV
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Bronchopulmonary Dysplasia
IVIG Trial for the Treatment of Bronchopulmonary Dysplasia
It is intended to examine the efficacy and safety of intravenous immunoglobulin(IVIG) for the bronchopulmonary dysplasia in preterms.
- Trial name
- NCT06925360
- Testing
- intravenous immunoglobulin
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- International Peace Maternity and Child Health Hospital
Preterm Neonate, Low Birthweight Neonate
Effectiveness Trial of Thermal Jacket
Globally, over 15 million neonates are born preterm each year. They account for approximately 30% of global neonatal deaths and 19% of total neonatal deaths in Bangladesh.
- Trial name
- NCT06277869
- Testing
- Thermal Jacket, Kangaroo Mother Care
- Where
- 3 sites in Bangladesh
- Volunteers
- 300 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Preterm Birth
Hammock Positioning's Influence on the Electromyographic Activity in the Flexor Muscles in Newborn Preterm
The individual who is born premature, in addition to a CNS still in accelerated training suffers early loss of intrauterine restraint, conditions that promote hypotonia characteristic of premature birth.
- Trial name
- NCT02621996
- Testing
- hammock, containment nest
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Parenteral Nutrition-Associated Liver Disease
Low Dose Parenteral Fat for Prevention of Parenteral Nutrition Associated Cholestasis in Preterm Neonates
The goal of the study is to determine if parenteral nutrition-associated cholestasis (PNAC) is related to the amount of parenteral (intravenous) fat administered to premature babies until full enteral nutrition is achieved.
- Trial name
- NCT01050660
- Testing
- Intravenous fat emulsion, Restriction of intravenous fat emulsion to 1 gm/kg/d
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Yale University
Bronchopulmonary Dysplasia (BPD), Prematurity
Oral Vitamin A Supplementation for Prevention of Bronchopulmonary Dysplasia in Preterm Infants
Bronchopulmonary dysplasia (BPD) remains a major complication of very low birth weight (VLBW) preterm infants. Vitamin A is essential for lung development and epithelial integrity, and deficiency has been associated with an…
- Conditions
- Bronchopulmonary Dysplasia (BPD), Prematurity, Very Low Birth Weight
- Trial name
- VITA-BPD (NCT07577180)
- Testing
- Vitamin A
- Where
- Turkey (Türkiye)
- Volunteers
- 209 people
- Sponsor
- Erhan Calisici
Retinopathy of Prematurity
Erythropoietin and Early Iron Supplement and Retinopathy of Prematurity
To evaluate the possibility that erythropoietin with early iron supplementation may induce retinopathy of prematurity or worsen this disease. In addition risk factors for the development of ROP will be checked.
- Trial name
- NCT00339001
- Testing
- erythropoietin and early iron supplements
- Where
- Israel
- Volunteers
- 400 people
- Sponsor
- Sheba Medical Center
Bronchopulmonary Dysplasia
Neurally Adjusted Ventilatory Assist vs Proportional Assist Ventilation
This study aims to assess whether neurally adjusted ventilatory assist or proportional assist ventilation is more effective in infants born prematurely with evolving or established bronchopulmonary dysplasia
- Trial name
- NCT02967549
- Testing
- NAVA, PAV
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- King's College London
Preterm Labor, Preterm Contractions
Screening To Obviate Preterm Birth
Our objective is to investigate the predictive value of a panel of biomarkers associated with two biologically plausible pathways of preterm birth: membrane breakdown and cervical remodeling.
- Conditions
- Preterm Labor, Preterm Contractions, Abdominal Cramping, Back Pain
- Trial name
- STOP (NCT01868308)
- Where
- United States
- Volunteers
- 589 people
- Sponsor
- University of Pennsylvania
Seizures, Epilepsy
Pharmacokinetics of Levetiracetam (Keppra) in Neonates
The primary objective of this study is to determine the pharmacokinetic profile of a loading dose of intravenous levetiracetam, given for clinical reasons, in term and late preterm infants with seizures.
- Trial name
- NCT01261416
- Testing
- levetiracetam
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
GERD
Efficacy and Safety of Esomeprazole Once Daily for the Treatment of GERD in Neonatal Patients
The purpose of this study is to assess the difference between esomeprazole and placebo in the treatment of signs and symptoms as observed by 8-hour video and cardiorespiratory monitoring in neonatal patients.
- Trial name
- NCT00427635
- Testing
- Esomeprazole
- Where
- 3 sites in Australia, Germany and 1 more
- Volunteers
- 32 people
- Sponsor
- AstraZeneca
Bronchopulmonary Dysplasia
Human Mesenchymal Stem Cells For Moderate and Severe Bronchopulmonary Dysplasia
This study is an open-label, single-center, dose escalation study to evaluate of safety and efficacy of human umbilical cord -derived mesenchymal stem cells (hUC-MSCs) in children with moderate and severe bronchopulmonary…
- Trial name
- NCT03601416
- Testing
- Transplantation of mesenchymal stem cell, No Transplantation of Mesenchymal Stem Cell
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Children's Hospital of Chongqing Medical University
Inguinal Hernia, Premature Birth of Newborn
Timing of Inguinal Hernia Repair in Premature Infants
The purpose of this study is to determine whether early (before NICU discharge) or late (55-60 weeks post-menstrual age) inguinal hernia repair is safer for premature infants who have an inguinal hernia.
- Trial name
- NCT01678638
- Testing
- IH repair before NICU discharge, IH repair at 55-60 weeks post-menstrual age
- Where
- 40 sites in United States
- Volunteers
- 338 people
- Sponsor
- Vanderbilt University Medical Center
Preterm, General Movements
Fidgety Movements of Preterm Neonates Included in COSGOD III
The evidence on the effects of clinical care with cerebral NIRS (Near-infrared spectroscopy) monitoring on short term neurological outcome, displayed by fidgety movements between six to 20 weeks post term, are still uncertain.
- Conditions
- Preterm, General Movements, Fidgety Movements, Near Infrared Spectroscopy
- Trial name
- Figdety_Ms (NCT06105333)
- Testing
- standard care plus cerebral oxygen saturation monitoring with a dedicated treatment guideline
- Where
- 2 sites in Austria
- Volunteers
- 183 people
- Sponsor
- Medical University of Graz
Retinopathy of Prematurity
Prospective Evaluation of iCam-OCT
This is a prospective, non-significant-risk clinical study sponsored by Siloam Vision, Inc. to evaluate whether ophthalmologists can assess retinopathy of prematurity (ROP) using images from the iCam-OCT device as effectively as…
- Trial name
- NCT07839923
- Testing
- imaged with i-Cam OCT
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Siloam Vision
Infant Premature
Randomized Controlled Trial of Higher-Volume Feedings in Preterm Neonates
The primary hypothesis is that preterm infants who are less than or equal to 32 weeks gestation and weigh 1001-2500 grams at birth will have an increase in weight gain with a feeding goal of 180-200 ml/kg/day more than the…
- Trial name
- NCT02377050
- Testing
- Higher Volume Feeding Goal
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- University of Alabama at Birmingham
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.