Clinical trials: Primary Arthrosis
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Primary Arthrosis, Post Traumatic Arthritis
2-Year Post-Approval Study to Investigate the Scandinavian Total Ankle Replacement System (STAR) Ankle Under Actual Conditions of Use
This post-approval study is being conducted to examine the performance of the STAR Ankle under actual conditions of use.
- Conditions
- Primary Arthrosis, Post Traumatic Arthritis, Rheumatoid Arthritis, Osteoarthritis
- Trial name
- STAR 2 PAS (NCT01284283)
- Testing
- Scandinavian Total Ankle Replacement System (STAR Ankle)
- Where
- 9 sites in United States
- Volunteers
- 102 people
- Sponsor
- Encore Medical, L.P.
Sjogren's Syndrome
The Functioning of Immune and Hormonal Systems in Patients With Sjogren's Syndrome and in Healthy Volunteers
This study aims to learn more about how the immune and hormonal systems function in patients with Sjogren's syndrome, a disease in which the immune system does not function properly.
- Trial name
- NCT00001953
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Epstein-Barr Virus (EBV) Infections, Lymphoproliferative Disorders
Expanded Access Protocol for Tabelecleucel for Patients With Epstein-Barr Virus-Associated Viremia or Malignancies
The primary objective of this protocol is to provide expanded access to tabelecleucel to participants with Epstein-Barr virus-associated diseases and malignancies for whom there are no other appropriate therapeutic options, and…
- Conditions
- Epstein-Barr Virus (EBV) Infections, Lymphoproliferative Disorders, EBV+ Associated Lymphoma, EBV+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD)
- Trial name
- NCT02822495
- Testing
- tabelecleucel
- Sponsor
- Atara Biotherapeutics
Knee Osteoarthrosis, Total Knee Arthroplasty
Patients' Experiences of Information After Total Knee Arthroplasty - A Qualitative Interview Study
The aim of this qualitative interview study is to gain new and in-depth knowledge about patients' experiences of information following total knee arthroplasty. Participants will be interviewed in the recovery phase after surgery.
- Trial name
- NCT06994884
- Where
- 2 sites in Sweden
- Volunteers
- 16 people
- Sponsor
- Vastra Gotaland Region
Patient Satisfaction, Hip Osteoarthritis
Dual Mobility Cup: Does it Improve Patient's Satisfaction After Total Hip Arthroplastry?
Although the success of total hip arthroplasty, many patients were dissatisfied postoperatively. Patient's reported outcome measures become of a great importance in assessment of the results after joint replacement.
- Trial name
- NCT04333316
- Testing
- large head, dual mobility cup
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Tanta University
Juvenile Idiopathic Arthritis, Systemic Lupus Erythematosus
The CARRA Registry
This CARRA Registry study will create a foundational database for rheumatic diseases of childhood using a novel informatics infrastructure developed as part of the larger clinical project.
- Conditions
- Juvenile Idiopathic Arthritis, Systemic Lupus Erythematosus, Mixed Connective Tissue Disease, Juvenile Ankylosing Spondylitis
- Trial name
- CARRA Registry (NCT01697254)
- Where
- United States
- Volunteers
- 9,587 people
- Sponsor
- Duke University
Osteoarthritis
Comparison of Anesthetic Techniques on Total Hip Arthroplasty
To compare analgesia and orthopedic rehabilitation milestones in patients receiving either spinal anesthesia (local anesthetic plus opioid) or general endotracheal anesthesia with lumbar plexus block.
- Trial name
- NCT01359865
- Testing
- Lumbar Plexus Block
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Disorder of Shoulder, Other Musculoskeletal Disorder
The Acute Effect of a Mobilization With Movement Technique to Improve Internal Rotation of the Shoulder
For many years researchers have been documented that the shoulder of the throwing athlete acquires a increase in external rotation of the dominant limb compared to the contralateral side.This fact is followed with a loss of the…
- Conditions
- Disorder of Shoulder, Other Musculoskeletal Disorder, Contracture
- Trial name
- NCT01639651
- Testing
- Posterior capsule stretching, Mobilization with movement
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Primary Osteoarthritis, Unspecified Shoulder
Effective Pain Management of Interscalene Blocks During Shoulder Surgery
Shoulder replacement surgery is recognized as having the potential to cause a considerable amount of postoperative pain. Adequate management of pain after surgery is necessary not only to improve the patient's wellbeing but also…
- Trial name
- NCT02267044
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- TriHealth Inc.
Mobile Application Actuated Rehabilitation Exercise Guidance, Routine Rehabilitation Exercise Guidance
Comparison of the Accuracy in Rehabilitation Exercise Between Mobile Application Actuated Rehabilitation Exercise Guidance and Routine Rehabilitation Exercise Guidance for the Primary Osteoarthritis Knee Patients
Evaluate the accuracy of physical therapy in various positions after 4 weeks of training, comparison of the accuracy in rehabilitation exercise between mobile application actuated rehabilitation exercise guidance and routine…
- Trial name
- NCT03666585
- Testing
- mobile application actuated rehabilitation exercise guidance, routine rehabilitation exercise guidance
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Navamindradhiraj University
Osteoarthritis in the Hip, Knee and Hand
Effect of an Education Programme for Patients With Osteoarthritis in Primary Care - a Randomized Controlled Trial
Osteoarthritis is a common disease. The core treatment is often patient education. The aim of this study is therefore to study the effect of a patient education programme for patients with osteoarthritis in primary health care.
- Trial name
- NCT00979914
- Testing
- Patient education programme
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Lund University
Knee Osteoarthritis, Hip Osteoarthritis
Mepivacaine Versus Low-Dose Bupivacaine For Primary Total Hip and Knee Arthroplasty
This research is being done to see if there is a difference between two different spinal anesthetics (Mepivacaine vs. Bupivacaine) as it relates to reducing post-operative complications and the time it takes for subjects to…
- Trial name
- NCT03838874
- Testing
- Low-Dose Bupivacaine, Mepivacaine
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Mayo Clinic
Hip Arthropathy Associated With Other Conditions
Long-term Aseptic Revision & Advanced Hip Arthroplasty Database
Total hip arthroplasty (THA) volumes continue to rise each year as the population ages and indications broaden. Increasingly, younger patients require hip replacement for conditions beyond primary osteoarthritis or fractures.
- Trial name
- LARA (NCT07481448)
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Primary Osteoarthritis, Secondary Osteoarthritis
Anthology Hip Replacement System - Orthopaedic Data Evolution Panel (ODEP) Surveillance Study
This clinical study will verify the clinical and radiographic performance of the prosthesis when used in human subjects over a period of 10 years. All complications will be documented.
- Conditions
- Primary Osteoarthritis, Secondary Osteoarthritis, Avascular Necrosis, Primary Total Hip Replacement (THR)
- Trial name
- NCT04425603
- Testing
- Anthology Hip Replacement System
- Where
- 4 sites in United Kingdom
- Volunteers
- 270 people
- Sponsor
- Smith & Nephew Orthopaedics AG
Autoimmune Lymphoproliferative Syndrome, Autoimmune Cytopenia
Conception of a Diagnosis, Prognosis and Therapeutic Decision Tool for Patients With Autoimmunity and Inflammation
The main objective of this study is to generate diagnosis and therapeutic-decision tools through the identification of molecular causes of PIDs with autoimmunity/inflammation and the variability in disease outcome at the…
- Conditions
- Autoimmune Lymphoproliferative Syndrome, Autoimmune Cytopenia, Autoimmune Diseases, Autoimmune Anemia
- Trial name
- ATRACTion (NCT04902807)
- Testing
- Collection of samples
- Where
- France
- Volunteers
- 325 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Shoulder Dislocation
Does Immobilization of the Shoulder in External Rotation Reduce the Recurrence Rate of Shoulder Dislocation?
Dislocation of the glenohumeral joint is the most common traumatic joint dislocation. The usual treatment of first time traumatic anterior dislocation of the shoulder is reduction followed by immobilization in a sling for a…
- Trial name
- NCT00202735
- Testing
- Arm1:Immobilization in external rotation, immobilization in internal rotation
- Volunteers
- 188 people
- Sponsor
- Sorlandet Hospital HF
Primary Sjögren's Syndrome
Study of Pharmacodynamic Effects of VAY736 in Patients With Primary Sjögren's Syndrome
This study consists of three consecutive parts. Part 1 in primary Sjögren's syndrome (pSS) patients (n=2-6) and Part 2 in healthy voluteers (n=3) are feasibility studies to assess if the selected [Zr-89]-rituximab PET/CT method…
- Trial name
- NCT02495129
- Testing
- VAY736 lower dose, VAY736 higher dose
- Sponsor
- Novartis Pharmaceuticals
Knee Osteoarthritis, Hip Osteoarthritis
The STavanger osteoARThritis Study
The START study will implement osteoarthritis (OA) treatment recommendations to increase the use of recommended treatment modalities and reduce non-desired events (e.g.
- Trial name
- START (NCT02876120)
- Testing
- Implementation
- Volunteers
- 330 people
- Sponsor
- Diakonhjemmet Hospital