Clinical trials: Primary Closure
Ischemic Stroke, Patent Foramen Ovale
Patent Foramen Ovale Closure or Anticoagulants Versus Antiplatelet Therapy to Prevent Stroke Recurrence
A patent foramen ovale (PFO) is found more frequently in patients with an ischemic stroke than in control subjects. Therapeutic options to prevent stroke recurrence include antiplatelet drugs, oral anticoagulants, and…
- Conditions
- Ischemic Stroke, Patent Foramen Ovale, Atrial Septal Aneurysm, Migraine
- Trial name
- CLOSE (NCT00562289)
- Testing
- aspirin, Antivitamins K or rivaroxaban or dabigatran or apixaban, Devices for PFO closure
- Where
- France
- Volunteers
- 664 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Glaucoma, Closed-Angle
Cataract Surgery Combined With Endoscopic Goniosynechialysis for Advanced Primary Angle Closure Glaucoma
In this prospective study, consecutive patients with advanced PACG and cataract who underwent Phaco-IOL-EGSL were invited to participate.
- Trial name
- NCT03686072
- Testing
- Cataract surgery with endoscopic goniosynechialysis
- Volunteers
- 19 people
- Sponsor
- Wenzhou Medical University
Bladder Exstrophy
Early Versus Delayed Closure of Bladder Exstrophy in Female Patients
This study compared two timings for primary single-stage surgery in female newborns with classic bladder exstrophy. Participants were randomly assigned to surgery within 72 hours of birth or at 6 to 12 weeks of age.
- Trial name
- NCT07794540
- Testing
- Early Primary Single-Stage Closure, Delayed Primary Single-Stage Closure
- Where
- Pakistan
- Volunteers
- 124 people
- Sponsor
- Khyber Teaching Hospital
Primary Angle-Closure Glaucoma
Predicting the Risk of Partial Ciliary Block After Cataract and Goniosynechialysis Surgery in Primary Angle-Closure Disease
Primary angle-closure disease (PACD) is a major cause of vision loss, often treated with a combined surgery that removes the eye's natural lens (cataract surgery) and physically opens the eye's drainage system…
- Trial name
- PCB-Risk (NCT07549438)
- Volunteers
- 1,150 people
- Sponsor
- Peking University People's Hospital
Evaluate and Compare Between Excision and Primary Closure Procedure and Rhomboid Flap Technique for the Treatment of Pilonidal Sinus, Duration of Operation,
Rhomboid Flap Versus Primary Closure After Excision of Sacrococcygeal Pilonidal Sinus. (A Prospective Randomized Study)
To evaluate and compare between excision with primary closure of wound and excision with Rhomboid flap reconstruction in the treatment of pilonidal sinus as regard duration of operation, healing time, hospital stay, complications…
- Trial name
- non (NCT01223599)
- Volunteers
- 140 people
- Sponsor
- Mansoura University
Tongue Squamous Cell Carcinoma
Oncological Outcome of Contralateral Submental Artery Island Flap Versus Primary Closure in Tongue Squamous Cell Carcinoma
The purpose of this study is to compare the oncological and functional results of the contralateral submental flap with primary closure for reconstruction of tongue squamous cell carcinoma.
- Trial name
- NCT03440151
- Testing
- contralateral submental flap for tongue cancer defect, primary closure for tongue cancer defect
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Cairo University
Glaucoma
The Genetic Study of Primary Angle-Closure Glaucoma
The purpose of this study is to evaluate the possible candidate gene of Primary Angle-Closure Glaucoma.
- Trial name
- NCT00155857
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Peritonitis, Primary Closure
Outcome of Primary vs Delayed Primary Closure of Laparotomy in Dirty Abdominal Wounds
This randomized controlled trial is designed to evaluate and compare two different wound management strategies-primary closure (PC) and delayed primary closure (DPC)-in patients undergoing emergency laparotomy for peritonitis The…
- Conditions
- Peritonitis, Primary Closure, Delayed Primary Closure
- Trial name
- NCT07531576
- Testing
- Delayed Primary Laparotomy wound Closure, Primary Abdominal Closure
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Ayub Teaching Hospital
Pilonidal Sinus
GLUtEus Maximus Fascia Plasty Flap for Pilonidal Sinus
Surgical treatment is still gold standard for pilonidal sinus disease. Several surgical techniques have been proposed to treat this disease in the last two decades.
- Trial name
- GLUE (NCT03914729)
- Testing
- Primary Closure, Gluteus Maximus Fascia Plasty Flap
- Where
- Russia
- Volunteers
- 84 people
- Sponsor
- Russian Society of Colorectal Surgeons
Total Anomalous Pulmonary Venous Connection, Pulmonary Venous Stenosis
Sutureless Closure for Primary Total Anomalous Pulmonary Venous Connection
The purpose of this study is to assess the percentage of pulmonary venous stenosis after TAPVC repair with sutureless closure.
- Conditions
- Total Anomalous Pulmonary Venous Connection, Pulmonary Venous Stenosis, Sutureless Closure
- Trial name
- TAPVC (NCT04938921)
- Where
- Vietnam
- Volunteers
- 30 people
- Sponsor
- Children's Hospital 1
Appendicitis, Surgical Wound Infection
Primary Versus Delayed Wound Closure in Complicated Appendectomy (The HIEDI-Yemen Trial)
The goal of this clinical trial is to compare primary wound closure (PC) versus delayed primary closure (DPC) after standardized wound decontamination using the High-Efficiency Incision and Drainage with Irrigation (HIEDI)…
- Conditions
- Appendicitis, Surgical Wound Infection, Postoperative Complications, Wound Healing
- Trial name
- HIEDI-Yemen (NCT07688109)
- Testing
- Primary Closure with HIEDI, Delayed Primary Closure with HIEDI
- Where
- 3 sites in Yemen
- Volunteers
- 200 people
- Sponsor
- Sana'a University
Cleft Palates
Preventing Complications in Cleft Palate Repair With Antibiotics
The primary objective of this study is to determine the efficacy of administering a single dose of preoperative antibiotics to prevent complications in patients undergoing primary closure of a cleft secondary palate.
- Trial name
- NCT00760006
- Testing
- Unasyn, saline solution
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- Joseph Losee
Management of CBD Stones
Laparoscopic Cholodochotomy in Management of CBD Stones
The aim of this study is to compare the outcomes of primary closure of cholodochotomy incision versus T-tube drainage in laparoscopic common bile duct exploration for management of CBD stones and provide evidence-based guidance…
- Trial name
- NCT06514911
- Testing
- primary closure following Laparoscopic cholodochotomy in management of CBD stones, T-tube drainage following Laparoscopic cholodochotomy in management of CBD stones
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Breast Neoplasms
New Formula to Predict the Need for Reconstructive Coverage Following Mastectomy
Mastectomy is a cornerstone operative procedure in breast cancer treatment leaving a raw area behind with possibility of failure of primary closure sometimes with unavailability of facilities of reconstruction.
- Trial name
- NCT04677075
- Testing
- mastectomy
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Zagazig University
Gastroschisis
Silo Versus Primary Closure for Gastroschisis
The objective of this study is to scientifically evaluate two different closure strategies for gastroschisis to determine if there is a difference in the two approaches.
- Trial name
- NCT01506531
- Testing
- silo for gastroschisis, Primary closure of gastroschisis
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Children's Mercy Hospital Kansas City
Wound Infection
Primary Versus Secondary Closure of Stoma-Reversal Skin Wound
to compare infection rate stoma reversal skin wound after primary or secondary closure
- Trial name
- NCT04785404
- Testing
- primary skin closure
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Ayub Teaching Hospital
Nasoalveolar Fistula (Defect)
Clinical Assessment of Usage of Cleft Margin Flap With Anterior Palatal Closure in Closure of Naso-alveolar Defect.
During primary cleft lip repair in patients who were born with cleft lip and palate, usage of cleft margin flap with anterior palatal closure will be done in an attempt to close the Naso-alveolar fistula (defect) that usually…
- Trial name
- NCT03922438
- Testing
- usage of cleft margin flap with anterior palatal closure during primary cleft lip repair.
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Narrow-Angle Glaucoma
Combined VCST With Phacoemulsification Versus Phacoemulsification in Primary Angle Closure Glaucoma
As ab externo metal probe trabeculotomy cannot achieve 360-degree circumferential angle surgery, prolene suture can be used to achieve this without the need for an illuminated microcatheter.
- Trial name
- NCT06120621
- Testing
- Arm 1 : VCST-phaco group , Arm 2 : phaco group.
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Migraine, Patent Foramen Ovale
Patent Foramen Ovale Closure in Migraine
The goal of this observational study is to retrospectively observe the effect of PFO closure and medication on migraine. The main questions it aims to answer are: Whether PFO closure is more effective in the treatment of migraine…
- Trial name
- NCT06192173
- Testing
- Percutaneous PFO closure
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Haiyan Wang
Infection Rates Between Primary Wound-closure (Allgower) and Secondary Wound Healing After Removal of an External Fixator
Wound Closure (Allgower) Versus Secondary Open Wound Healing After Removal of the External Fixator
In this prospective randomized controlled single-center trial, based on a non-inferiority design, the outcome of the treatment of patients are analyzed, whereas in half of the cases the wounds are left open and the other ones are…
- Trial name
- Pinsides (NCT03842956)
- Testing
- Primary wound closure in Allgower Technique vs. secondary open wound healing of pin-sides after removal of the fixated-externe
- Where
- Switzerland
- Volunteers
- 241 people
- Sponsor
- Luzerner Kantonsspital