Clinical trials: Primary Headache Disorder
Tension Headache
Suboccipital Inhibition in Tension Headache
The researchers will carry out a randomized experimental study. Participants in the experimental group will receive a treatment based on suboccipital inhibition technique in addition to conventional treatment.
- Trial name
- NCT04376125
- Testing
- Suboccipital inhibition in tension headache
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de León
Migraine, Tension Type Headache
Effectiveness of a Cognitive and Physical Intervention to Reduce Head and Muscle Pain in a Large Population
This study is an interventional trial to evaluate the effectiveness of a cognitive and physical program (Intervention), in reducing the frequency of head and neck pain in the population of an extensive territory of Italy.
- Conditions
- Migraine, Tension Type Headache, Cervical Pain
- Trial name
- NCT01050972
- Testing
- Behavioral: Cognitive, Relaxation, Exercise Therapy
- Where
- Italy
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Migraine
Intranasal Lidocaine to Treat Pediatric Migraine in the Emergency Department
The purpose of the study is to determine the effect of intranasal lidocaine on pain score in pediatric patients with migraine. Patients with significant pain after oral analgesics and plan for intravenous (IV) abortive therapy…
- Trial name
- NCT03576820
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- New York City Health and Hospitals Corporation
Migraine Disorders
A Pharmacokinetic Study to Evaluate TREXIMET in Adolescents With Migraine and Healthy Subjects Administered at Three Doses.
This is a pharmacokinetic (PK) study designed to investigate a combination product containing sumatriptan succinate and naproxen sodium administered at 3 single doses (10mg sumatriptan/60mg naproxen sodium, 30mg sumatriptan/180mg…
- Trial name
- NCT00989625
- Testing
- This is a pharmacokinetic study (Treximet)
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Migraine, Magnesium, Pediatric
Serum Magnesium Level and Pediatric Migraine
Aim: The purpose of this study is to compare serum magnesium levels between patients with migraine and a control group and to examine the relationship between the frequency and duration of attacks in patients with migraine and…
- Trial name
- Migraine (NCT06274255)
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mersin University
Migraine
Puberty, Sex Hormones and Pain Sensitivity in Adolescents With Migraine
The purpose of this research study is to investigate the relationships between sex hormone levels and experimental pain sensitivity and migraine severity will be examined.
- Trial name
- IHS (NCT05738213)
- Testing
- Thermal stimuli, Pressure stimuli, Pain ratings
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Migraine in Children
Uric Acid Levels and Migraine in Children
Migraine is recognized as one of the most prevalent neurological disorders. The exact pathophysiological mechanisms underlying migraine have not yet been fully elucidated.
- Trial name
- NCT06966037
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Aysen Orman
Migraine, Allergic Rhinitis
Is There a Comorbidity Between Migraine and Allergic Rhinitis?
The researchers investigated the relationship between migraine and allergy. For this purpose, the researchers designed a controlled study to evaluate nasal symptoms and signs; and to perform Specific Immunoglobulin E (IgE)…
- Trial name
- NCT01845051
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Baskent University
Migraine, Tension Type Headache
The Efficacy of a Cognitive and Physical Intervention to Reduce Head and Muscle Pain in a Working Community
This study is a controlled, cluster randomised, interventional trial to evaluate the effectiveness of a workplace cognitive and physical program (Intervention), in reducing the frequency of head and neck pain in an extensive…
- Conditions
- Migraine, Tension Type Headache, Cervical Pain
- Trial name
- NCT00551980
- Testing
- Cognitive, Relaxation, Exercise Therapy
- Where
- Italy
- Volunteers
- 2,895 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Migraine, Endometriosis
Endometriosis and Migraine
This study aims to determine differences in experimental pain and sex hormone levels between patients with migraine, patients with endometriosis, patients with migraine and endometriosis, and healthy controls.
- Trial name
- EMC (NCT06785129)
- Testing
- Thermal stimuli, Pressure stimuli, Pain ratings
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Migraine, Musculoskeletal Pain
Overlapping Pain Trajectory Study
The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1.
- Conditions
- Migraine, Musculoskeletal Pain, Functional Abdominal Pain Disorders, Chronic Pain
- Trial name
- COPC (NCT05752396)
- Testing
- Conditioned Pain Modulation, Offset Analgesia, Spatial Summation
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Migraine Disorders
Testing myWHI: Online Self-help Programs for Headaches
This randomized controlled trial will compare the effectiveness of two online self-guided programs for youth and young adults with migraine against usual care.
- Trial name
- NCT03504150
- Testing
- SPHERE, PRISM
- Where
- Canada
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Tension-Type Headache
Effect Of Extracorporeal Shockwave Therapy on Tension-Type Headache in Adolescent Females
Chronic headaches in adolescents can have consequences such as absence from school, inability to maintain social activities, and additional disorders such as anxiety, depression, problems sleeping, and reduced quality of life to…
- Trial name
- NCT06482736
- Testing
- Extracorporeal Shockwave Therapy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- October 6 University
Headaches
RCT Evaluating Intranasal Fentanyl in the Pain Management of Children With Headaches
Background : Headaches are a common presentation for children consulting to the Emergency Department (ED). However, only few studies have evaluated the rapid pain improvement provided by medications in the acute management of…
- Trial name
- NCT02638506
- Testing
- Fentanyl, Salinex
- Where
- Canada
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Migraine
Influence of a Dietary Supplement as Treatment of Migraine in Children and Adolescents
Migraine in children and adolescents can be associated with low serum levels of coenzyme q10, the key-enzyme of mitochondrial energy production.During migraine attacks inflammation is an important issue.
- Trial name
- NCT01010711
- Testing
- Migra 3
- Where
- 2 sites in Germany
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Complen Health GmbH
Headache, Migraine
Adolescent Lifestyle Medicine Headache Study
The goal of this pilot clinical trial is to assess the implementation of a 7-week Lifestyle Medicine intervention for adolescents with headache.
- Trial name
- NCT07373275
- Testing
- Lifestyle Medicine Group Medical Visits
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- MaineHealth
Familial Hemiplegic Migraine
Calcitonin Gene Related Peptide-Induced Headache in Patients With Familial Hemiplegic Migraine Type 1 and 2.
The aim of the present study is to explore functional consequences of migraine gene mutations on their responses to Calcitonin Gene Related Peptide (CGRP)infusion.
- Trial name
- NCT00358839
- Testing
- CGRP
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Migraine, Pediatric Migraine
PEDİATRİC MİGRAİNE PATİENTS İN FİNDİNGS
Migraine is a common neurological disease in the pediatric population. However, studies investigating the clinical symptoms associated with the different phases of migraine attacks (prodrome, aura, postdrome), particularly in…
- Trial name
- NCT07593287
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Mersin University
Migraine, Migraine in Children
Intravenous Fluids in Pediatric Migraine
The goal of this clinical trial is to compare intravenous (IV) fluids in pediatric patients with migraine. The main questions it aims to answer are: Does a large amount of fluids (bolus) improve pain Does a large amount of fluids…
- Trial name
- NCT06182098
- Testing
- 1/2 maintenance fluids, Ketorolac, Diphenhydramine
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Dayton Children's Hospital