Clinical trials: Primary Neoplasm
Congenital Heart Disease
Multi-micronutrient Supplementation During Peri-conception and Congenital Heart Disease
The purpose of this study is to determine whether daily oral supplements of vitamin B complex along with folic acid or supplements of iron plus folic acid given to women during peri-conception can reduce the risk of congenital…
- Trial name
- NCT02537392
- Testing
- Vitamin B Complex and Folic Acid, Iron and Folic Acid, Folic Acid
- Where
- China
- Volunteers
- 7,315 people
- Sponsor
- Xi'an Jiaotong University
Stroke, Ischemic Attack, Transient
Home Blood Pressure Monitoring Trial
Design: Community based randomised trial with follow up after 12 months Participants: 360 patients admitted with stroke or TIA within the past 9 months will be recruited from the wards or outpatients and randomly allocated into…
- Trial name
- NCT00514800
- Testing
- Intervention - a validated home BP monitor and support from the specialist nurse, Control - usual care (BP monitoring by their practice)
- Where
- 3 sites in United Kingdom
- Volunteers
- 360 people
- Sponsor
- St George's, University of London
Long QT Syndrome
Low Cost QTc Meter for Long QT Syndrome Screening in Primary Care
The purpose of this study is to further develop and evaluate a diagnostic procedure suitable for use in an inexpensive diagnostic instrument suitable for screening for Long QT Syndrome (LQTS) in the primary care environment.
- Trial name
- NCT04441892
- Testing
- QTc Meter
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Mayo Clinic
Meningococcal Disease
Phase 2, Observer-Blind, Placebo-Controlled, Randomized, Multi-Center Extension Study to Evaluate the Safety and Immunogenicity of a Booster Dose of a MenABCWY Vaccine Administered 24 Months Following the Primary Series to Adolescents and Young Adults Who Participated in V102_03 (NCT01272180)
The purpose of this extension study is to evaluate the immunogenicity and safety of a booster dose of a MenABCWY vaccine, administered 24 months after completion of the primary vaccination series, in subjects who previously…
- Trial name
- NCT01992536
- Testing
- MenABCWY+OMV, MenABCWY+¼OMV
- Where
- 13 sites in United States, Poland
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Breast Cancer, Pregnancy
Primary Breast Cancer Occurring Concomitant With Pregnancy
The goal of this clinical research study is to learn the results of multimodality (chemotherapy, surgery and radiation therapy) treatment of primary breast cancer that occurs at the same time as pregnancy.
- Trial name
- NCT00510367
- Testing
- 5-Fluorouracil, Cyclophosphamide, Doxorubicin
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- M.D. Anderson Cancer Center
Primary Nephrotic Syndrome
The Clinical Application Study of Obinutuzumab in Pediatric Refractory Nephrotic Syndrome
Primary nephrotic syndrome (PNS) in children is a clinical syndrome characterized by massive proteinuria, hypoalbuminemia, edema, and hyperlipidemia.
- Trial name
- Obinutuzumab (NCT07612592)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Children's Hospital of Chongqing Medical University
Cytopenia
Autoimmune Cytopenias as a Sign of Primary Immunodeficiency.
Autoimmune cytopenias resistant to treatment are among the most common clinical manifestations observed in patients with congenital alterations of the immune system, such as primary immunodeficiencies (PI).
- Trial name
- NCT06276036
- Testing
- Identification of specific markers
- Where
- 6 sites in United States, Belgium and 1 more
- Volunteers
- 53 people
- Sponsor
- Meyer Children's Hospital IRCCS
Dentin Caries
Comparison Of Clinical And Radiological Success Of Pulpotomy Treatments Performed With Proroot MTA, NeoPUTTY MTA, TheraCal PT In Primary Teeth
The goal of this randomized clinical trial is to compare clinical and radiological success rates of NeoPutty MTA, ProRoot MTA and TheraCal PT pulpotomy in 4-10 years old healthy pediatric patients.
- Trial name
- NCT07260357
- Testing
- ProRoot MTA Pulpotomy, NeoPUTTY MTA Pulpotomy, TheraCal PT Pulpotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Neonatal Abstinence Syndrome
Treatment of Neonatal Abstinence Syndrome With Clonidine Versus Morphine as Primary Therapy
The purpose of this study is to show non-inferiority between two medications used for medical treatment of withdrawal seen in Neonatal Abstinence Syndrome (NAS), Clonidine and Morphine Sulfate (used in routine care) on length of…
- Trial name
- NCT03092011
- Testing
- Clonidine, Morphine Sulfate
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- The Cooper Health System
Primary Hypertension
The Effect of Lavender Inhalation on Anxiety, Sleep, and Blood Pressure
This study aims to determine the effects of lavender oil inhalation on anxiety, sleep quality, and blood pressure in patients with primary hypertension. The study is designed as a double-blind randomized controlled trial.
- Trial name
- NCT07192783
- Testing
- Lavender
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ardahan University
Primary Monosymptomatic Nocturnal Enuresis
Posterior Tibial Nerve Stimulation Vs Desmopressin In Children With Primary Monosymptomatic Nocturnal Enuresis
Nocturnal enuresis is a worldwide health problem frequently encountered in childhood . It affects 18 % of younger school- age children in Egypt.
- Trial name
- PTNS (NCT04545931)
- Testing
- Posterior tibial nerve stimulation, Desmopressin Acetate
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Bloom Syndrome
Biological Significance of the Bloom's Syndrome Protein
Since 1960, persons with the very rare disorder Bloom's syndrome (BS) have been followed clinically, documenting clinical matters as obtained from their doctors.
- Trial name
- NCT00021437
- Where
- United States
- Sponsor
- National Center for Research Resources (NCRR)
Familial Hemiplegic Migraine
Calcitonin Gene Related Peptide-Induced Headache in Patients With Familial Hemiplegic Migraine Type 1 and 2.
The aim of the present study is to explore functional consequences of migraine gene mutations on their responses to Calcitonin Gene Related Peptide (CGRP)infusion.
- Trial name
- NCT00358839
- Testing
- CGRP
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Depression
Study of Whether Educational Visits to Primary Care Professionals Improves the Quality of Care They Provide.
The purpose of this study is to find out whether educational visits by Pharmacists, who are already employed as advisers in health organisations, improve the prescribing habits of primary care doctors.
- Trial name
- NCT00393536
- Testing
- Educational outreach visiting
- Where
- United Kingdom
- Volunteers
- 73 people
- Sponsor
- Newcastle University
Human Papillomavirus
Human Papilloma Virus (HPV) Vaccination Among Rural African American Primary Caregivers and Daughters
African American women living in the rural South are twice as likely as Caucasian women to develop cervical cancer and die of invasive cervical cancer at a higher rate than any other racial/ethnic group in the US (1).
- Trial name
- NCT00937287
- Testing
- There is no intervention in this study.
- Where
- United States
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Physiological Root Resorption of Primary Teeth
The Effect of Physiological Root Resorption in Primary Teeth on the Success of Pulpotomy Treatment
The aim of our study was to evaluate the effect of physiological root resorption on the success of pulpotomy treatment performed using a calcium silicate-based material on primary second molars with deep dentin caries.
- Trial name
- NCT07834814
- Testing
- Pulpotomy treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Aydin Adnan Menderes University
Acute Rhinosinusitis
Effectiveness and Safety of Once or Twice Daily Mometasone Nasal Spray Versus Amoxicillin Versus Placebo for Treatment of Acute Rhinosinusitis (Phase 3 Study)(Study P02692)
This study was conducted to compare the effectiveness and safety of mometasone nasal spray once daily or twice daily with amoxicillin or with placebo in treating the signs and symptoms of acute rhinosinusitis.
- Trial name
- NCT00751075
- Testing
- mometasone furoate nasal spray (MFNS), MFNS, Amoxicillin
- Volunteers
- 981 people
- Sponsor
- Organon and Co
Enuresis
A Study to Determine if Ibuprofen in Combination With Pseudoephedrine HCl is More Effective Than Each Drug Alone in the Treatment of Nighttime Bedwetting
The purpose of the study is to determine if ibuprofen in combination with pseudoephedrine HCl in the treatment of nightime bedwetting in children is more effective than each drug alone and if the individual drugs are more…
- Trial name
- NCT00240812
- Testing
- ibuprofen; pseudoephedrine HCl
- Volunteers
- 318 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Cancer of Unknown Primary Site
Carcinoma of Unknown Primary (CUP): a Comparison Across Tissue and Liquid Biomarkers
Patients with Carcinoma of Unknown Primary (CUP) have widespread cancer at diagnosis however the specific site of origin cannot be found, despite significant testing, making it difficult to treat.
- Trial name
- CUP-COMP (NCT04750109)
- Where
- 7 sites in United Kingdom
- Volunteers
- 117 people
- Sponsor
- The Christie NHS Foundation Trust
Japanese Encephalitis
Immunogenicity of a JE-CV as a Booster Dose After a Primary Vaccination With SA14-14-2 Vaccine
The objective of this study is to measured the Geometric mean titer (GMT) of Japanese Encephalitis neutralizing antibody and proportion of seroprotection among the children who received a booster dose of JE-CV after the first…
- Trial name
- NCT02602652
- Testing
- a live attenuated chimeric JE vaccine
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
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