Clinical trials: Primary Open-angle Glaucoma and Ocular Hypertension
Glaucoma, Open-Angle, Ocular Hypertension
A Study of 0.03% Bimatoprost in the Treatment of Primary Open Angle Glaucoma and Ocular Hypertension
This study will evaluate 0.03% bimatoprost in the treatment of primary open angle glaucoma and ocular hypertension.
- Trial name
- LOTUSDI (NCT02020512)
- Testing
- 0.03% Bimatoprost
- Where
- China
- Volunteers
- 87 people
- Sponsor
- Allergan
Primary Open Angle Glaucoma
Results of Ocular Compression and Suture Release in Trabeculectomy and Combined Surgery
The use of ocular compression and suture release have helped to improve the safety and decrease the risks of glaucoma filtering surgery.
- Trial name
- NCT00327405
- Where
- United States
- Sponsor
- University of Cincinnati
Congenital Glaucoma
Genetic Testing in Primary Congenital Glaucoma Patients
Primary congenital glaucoma patients and their immediate relatives will undergo complete ophthalmic examination and an interview with a geneticist. A blood sample will be drown from all participants for DNA analysis.
- Trial name
- NCT01136460
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Primary Congenital Glaucoma
Iris Tissue in Primary Congenital Glaucoma
To present the histopathological features of the iris tissue in primary congenital glaucoma which may play a role in pathogenesis
- Trial name
- NCT04079725
- Testing
- Combined trabeculotomy-trabeculectomy with mitomycin c
- Volunteers
- 15 people
- Sponsor
- Assiut University
Primary Congenital Glaucoma
MicrocatheterTrabeculotomy in Primary Congenital Glaucoma
PURPOSE: To study circumferential trabeculotomy for congenital glaucoma using Glaucolight illuminated microcatheter. Setting: Ophthalmology department, Faculty of Medicine, Minia University, 61519, El-Minia, Egypt.
- Trial name
- NCT04116450
- Testing
- Glaucolight illuminated microcatheter.
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Minia University
Glaucoma, Glaucoma, Open-Angle
Pigment Dispersion Syndrome With and Without Glaucoma
To compare patients having PDS without and with OH or GL by documenting and following the clinical features and course of their disease and evaluating the patient's performance on a variety of diagnostic tests.
- Conditions
- Glaucoma, Glaucoma, Open-Angle, Ocular Hypertension
- Trial name
- NCT00001152
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- National Eye Institute (NEI)
Primary Congenital Glaucoma
Long Term Evaluation of Primary Congenital Glaucoma Management in Sohag University Hospital
evaluation of primary congenital glaucoma management in sohag university hospital
- Trial name
- PCG (NCT04949555)
- Testing
- Primary congenital glaucoma evaluation
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Sohag University
Glaucoma, Open-Angle
An Observational Multicenter Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System In Pseudophakic Eyes With Primary Open Angle Glaucoma (ORION 2.0)
The purpose of this study is to evaluate the safety and effectiveness of the OMNI® Surgical System in subjects who have undergone canaloplasty and trabeculotomy using OMNI® Surgical System without any concomitant surgery in…
- Trial name
- NCT04872348
- Testing
- OMNI® Surgical System
- Where
- 10 sites in United States
- Volunteers
- 28 people
- Sponsor
- Sight Sciences, Inc.
Primary Congenital Glaucoma
Evaluation of Primary Congenital Glaucoma at Asyut University Hospital
Evaluation of the management of primary congenital glaucoma regarding the results of surgical intervention at Asyut University Hospital
- Trial name
- NCT05205122
- Testing
- Combined trabeculotomy-trabeculectomy with mitomycin C
- Volunteers
- 30 people
- Sponsor
- Omar Abdelkarem Hasan
Glaucoma, Open-Angle, Ocular Hypertension
A Study of 0.15% Brimonidine Tartrate in Patients With Primary Open Angle Glaucoma and Ocular Hypertension
This study will evaluate 0.15% brimonidine tartrate in patients with primary open angle glaucoma and ocular hypertension.
- Trial name
- APOTUS (NCT02003534)
- Testing
- 0.15% Brimonidine Tartrate
- Where
- China
- Volunteers
- 376 people
- Sponsor
- Allergan
Primary Congenital Glaucoma
Surgery for Primary Congenital Glaucoma in Neonates
The current study aimed to compare between the long-term surgical outcomes of 3 surgical options (viscotrabeculotomy (VT), visco-circumferential-suture-trabeculotomy (VCST) or combined VT-Trabeculectomy with MMC (VT-Trab) in…
- Trial name
- NCT04709497
- Testing
- viscotrabeculotomy (VT), visco-circumferential-suture-trabeculotomy (VCST) ., combined VT-Trabeculectomy with MMC (VT-Trab).
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Ocular Hypertension, Primary Open Angle Glaucoma
A Study of Ganfort Versus Duotrav in Patients With Primary Open Angle Glaucoma or Ocular Hypertension
This is a single-center, cross-over comparison parallel group randomized trial designed to evaluate the efficacy and safety of Ganfort compared to Duotrav for a treatment period of 8 weeks each.
- Trial name
- NCT01168414
- Testing
- Ganfort, Duotrav
- Where
- Malaysia
- Volunteers
- 42 people
- Sponsor
- Ministry of Health, Malaysia
Primary Congenital Glaucoma
Combined Nasal Goniotomy-Temporal Trabeculotomy Versus Temporal Trabeculotomy for Management of Primary Congenital Glaucoma
Combined nasal goniotomy and temporal trabeculotomy provides effective IOP control in PCG while preserving the superior conjunctiva for future filtering procedures.
- Trial name
- NCT07830017
- Testing
- combined Nasal goniotomy-Temporal trabeculotomy, Temporal trabeculotomy
- Where
- Egypt
- Volunteers
- 21 people
- Sponsor
- Zagazig University
Optical Coherence Tomography, Anterior Chamber Angle
Optical Coherence Tomography of the Irido-Corneal Angle Before and After Goniotomy and Trabeculotomy in Primary Congenital Glaucoma
The research aimed to improve surgical techniques and long-term outcomes by utilizing this advanced imaging technology to illuminate the structural abnormalities of the anterior segment in eyes with primary congenital glaucoma.
- Conditions
- Optical Coherence Tomography, Anterior Chamber Angle, Goniotomy, Trabeculotomy
- Trial name
- NCT07012252
- Testing
- Optical coherence tomography
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Cairo University
Primary Congenital Glaucoma, Pediatric Glaucoma
Subscleral Trabeculectomy With Inverted T-Shaped Deep Sclerectomy for Primary Congenital Glaucoma
Primary congenital glaucoma (PCG) is a vision-threatening disorder of childhood characterized by elevated intraocular pressure (IOP) resulting from developmental abnormalities of the anterior chamber angle.
- Conditions
- Primary Congenital Glaucoma, Pediatric Glaucoma, Intraocular Pressure
- Trial name
- TDS-PCG (NCT07701278)
- Testing
- Subscleral Trabeculectomy Combined With Inverted T-Shaped Deep Sclerectomy
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Benha University
Primary Open Angle Glaucoma
Comparison of Retinal Nerve Fiber Layer (RNFL) Thickness Measurements by Time-Domain and Spectral-Domain OCT In Glaucoma Patients
Measurement of RNFL thickness by OCT is at a cornerstone for the correct diagnosis and monitoring of progression of glaucomatous optic neuropathy.
- Trial name
- NCT00773877
- Where
- South Korea
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Glaucoma, Congenital Glaucoma
Kahook Dual Blade Ab-interno Trabeculotomy Versus ab Externo Viscotrabeculotomy in Primary Congenital Glaucoma
This prospective study aims to compare KDB ab-interno trabeculotomy to ab externo rigid probe viscotrabeculotomy in patients with PCG.
- Trial name
- NCT05115708
- Testing
- ab externo viscotrabeculotomy, The Kahook dual blade® (KDB) assisted ab-interno trabeculotomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Primary Congenital Glaucoma, Goniotomy
Goniotomy in Primary Congenital Glaucoma
Brief Summary This is a multicenter cohort study designed to evaluate and compare the efficacy and safety of different surgical extents of goniotomy (GT) - specifically 120°, 240°, and 360° - in the treatment of Primary…
- Trial name
- NCT07550868
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Sun Yat-sen University
Primary Congenital Glaucoma, Developmental Glaucoma
Comparison of Surgical Treatment Options for Primary Congenital and Developmental Glaucomas
Newborn and children can be affected by two subgroups of this disease: (1) primary congenital glaucoma (PCG) or (2) developmental glaucoma (DG).
- Trial name
- STOP-Glaucoma (NCT04647929)
- Testing
- Santen PRESERFLO MicroShunt, Trabeculectomy
- Sponsor
- University of Zurich
Primary Congenital Glaucoma
The Genetic Characteristics in South Korean Patients With Primary Congenital Glaucoma
Primary congenital glaucoma, which presents at birth or in infancy, if left untreated, may threaten vision. The incidence of congenital glaucoma varies among different geographic locations and ethnic groups.
- Trial name
- NCT01020721
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center