Clinical trials: Probes
Respiratory Infections
Exploratory Study of Intrapulmonary Microdosing of Gram-negative Optical Imaging Detection Probe
Critically ill patients are often ventilated in dedicated critical care units to provide respiratory support. Despite best practice patients can often develop a condition called adult respiratory distress syndrome (ARDS), which…
- Trial name
- BAC TWO (NCT02491164)
- Testing
- BAC TWO, FE and Cellvizio viewer software
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- University of Edinburgh
CDKL5 Deficiency Disorder
Efficacy and Safety of Daily Home-based Hyperthermic Baths for Reducing Epileptic Seizures in CDKL5 Deficiency Disorder: A PROBE Clinical Trial
The primary objective of this research is to study the efficacy and safety of daily, home-based hyperthermic baths for reducing epileptic seizures in CDKL5 Deficiency Disorder.
- Trial name
- NCT07602205
- Testing
- Home-based hyperthermic Baths
- Volunteers
- 34 people
- Sponsor
- Xuanwu Hospital, Beijing
Skin Cancer
Melanoma Detection by Oblique-Incidence Optical Spectroscopy
Primary Objectives: To establish a statistically significant database: With Spectroscopic Oblique-Incidence Reflectometry (OIR) experimental system, we will obtain OIR spatio-spectral images of 1,000 human skin non-melanocytic…
- Trial name
- NCT00526032
- Testing
- OIR Imaging
- Where
- United States
- Volunteers
- 490 people
- Sponsor
- M.D. Anderson Cancer Center
Radial Artery Catheterization, Paediatric
Innovative Probe With Laser on Radial Artery Puncture and Catheterisation in Paediatric
During prolonged major surgical procedures in paediatric, significant fluctuations in vital signs occur. To ensure real-time, precise monitoring of haemodynamic parameters such as blood pressure and heart rate for maintaining…
- Conditions
- Radial Artery Catheterization, Paediatric, Ultrasound Guided
- Trial name
- NCT07454005
- Testing
- T-shaped probe ultrasound guidance, Out-of-plane ultrasound guidance
- Where
- China
- Volunteers
- 408 people
- Sponsor
- The First Hospital of Jilin University
Gastro-oesophageal Reflux
A Validation Study of the Dx-pH Probe in Children for the Detection of Extra-oesophageal Reflux
Gastro-oesophageal reflux (GORD) and its extraoesophageal manifestations present with a variety of symptoms in both adult and paediatric populations.
- Trial name
- NCT02457429
- Testing
- Experiemental diagnostic procedure: Dx-pH measurement system, Peptest assay, GORD symptom questionnaire
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- Manchester University NHS Foundation Trust
Breast Cancer
Cryosurgery in Treating Women With Breast Lesions
RATIONALE: Cryosurgery kills cancer cells by freezing them. Cryosurgery followed by lumpectomy or mastectomy may be an effective treatment for breast lesions.
- Trial name
- NCT00020852
- Testing
- conventional surgery, cryosurgery
- Where
- United States
- Sponsor
- Jonsson Comprehensive Cancer Center
Gingival Phenotype
Assessment of Gingival Thickness Using Colored Periodontal Probe
the accuracy of different assessment methods of the gingival tissue thickness can be controversial affecting their correct classification and the techniques of gingival tissue management in case of mucogingival problems.
- Trial name
- NCT05706480
- Testing
- colored periodontal probes (CPP), standard periodontal probes (SPP), transgingival sounding with an endodontic file
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Misr International University
Menopause, Urinary Incontinence
Evaluation of the Safety and Performance of the MILTA GYNECO Vaginal Probe in Postmenopausal Women With Vaginal Atrophy
Vulvovaginal atrophy is common after menopause, with a significant negative effect on quality of life. Large cohort studies have reported the prevalence of vaginal dryness to be between 27% and 55% and dyspareunia between 32% and…
- Conditions
- Menopause, Urinary Incontinence, Atrophic Vaginitis
- Trial name
- SIVAM (NCT05058313)
- Testing
- Photobiomodulation
- Where
- 3 sites in France
- Volunteers
- 25 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Prostate Cancer, Breast Cancer
Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis
Background: Some genes may be associated with a greater chance of side effects during cancer treatment. These genes may also make certain treatments less effective.
- Conditions
- Prostate Cancer, Breast Cancer, Lung Cancer, Ovarian Cancer
- Trial name
- NCT01441089
- Where
- United States
- Volunteers
- 1,100 people
- Sponsor
- National Cancer Institute (NCI)
Steatosis, Obesity
Evaluation of the Diagnostic of Hepatic Fibrosis With the in Severe Obese Patients Candidates to Bariatric Surgery
Background: The XL probe of FibroScan was recently developed to realize liver stiffness measurements (LSM) in overweight patients.
- Conditions
- Steatosis, Obesity, Fibrosis, Liver
- Trial name
- NCT03548597
- Testing
- Evaluation of the Diagnostic of Hepatic Fibrosis With the XL Probe of the Fibroscan Versus Biopsies in Severe Obese Patients Candidates to Bariatric Surgery
- Volunteers
- 132 people
- Sponsor
- European Georges Pompidou Hospital
Bladder Cancer
Evaluation of Ultrasound Probe for Use in Bladder Radiotherapy
Muscle-invasive bladder cancer affects over 3,000 new patients in the UK each year and radiotherapy comprises a key part of the treatment pathway for many of them.
- Trial name
- NCT01698359
- Where
- United Kingdom
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Obesity, Pregnancy
A Trial of the Use of Ultrasound to Aid the Insertion of Combined Spinal Epidural Anaesthesia
The study will establish whether the use of ultrasound scanning with a purpose built probe will aid the insertion of the needles for epidural and spinal anaesthesia for obese women undergoing elective caesarean section The study…
- Trial name
- NCT00166699
- Testing
- ultrasound
- Where
- 5 sites in United Kingdom
- Volunteers
- 42 people
- Sponsor
- NHS Greater Glasgow and Clyde
Focus of Study is on Dentist's Attitudes Toward BP Measures
Dental PROBE (Dental Practice suRvey of Office Blood Pressure mEasurement)
20% of Canadians are hypertensive with approximately 200,000 new cases each year. Early detection of hypertension affects outcomes, reducing the risk for heart attack, stroke, kidney disease, and dementia.
- Trial name
- Dental-PROBE (NCT01604200)
- Testing
- focus group
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Pain, Procedural
Pain Assessment in the Perioperative Area
This study is mainly focusing on reducing the pain scores during IV cannulation in pediatric population in the preoperative period. Applying EMLA cream is a well-known fact world wide.
- Trial name
- EMLA (NCT04212208)
- Testing
- IV cannulation
- Where
- India
- Volunteers
- 120 people
- Sponsor
- All India Institute of Medical Sciences, Rishikesh
Gastric Intestinal Metaplasia
The Learning Curve of Probe-based Confocal Laser Endomicroscopy (pCLE) Images Interpretation in Gastric Intestinal Metaplasia (GIM)
The Learning Curve of Probe-based Confocal Laser Endomicroscopy (pCLE) images interpretation in Gastric Intestinal Metaplasia (GIM) Objective: The aim of this study is to evaluate the learning curve of pCLE images interpretation…
- Trial name
- NCT01491724
- Where
- Thailand
- Volunteers
- 5 people
- Sponsor
- King Chulalongkorn Memorial Hospital
Breast Cancer
Molecular Marker Profiling of Axillary Lymph Nodes in Predicting Response in Patients With Locally Advanced or Metastatic Breast Cancer Who Are Undergoing Chemotherapy Followed By Surgery
RATIONALE: Comparing results of diagnostic procedures, such as molecular marker profiling, done before and after chemotherapy, may help doctors predict a patient's response to treatment and help plan the best treatment.
- Trial name
- NCT00233974
- Testing
- PET (positron emission tomography)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Children in Cardiac Intensive Care Requiring Surgery for Congenital Heart Disease
Antibiotics Distribution Study in Peripheral Compartments: Contribution of Microdialysis
Postoperative mediastinitis is an important cause of postoperative morbidity in children. The main objective of this study is to describe the distribution of cefazolin, using as surgical antibiotic prophylaxis, in the mediastinal…
- Trial name
- Antimidis (NCT07327502)
- Testing
- Microdialysis probe placement, Microdialysis and Plasma samples
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hemoglobin Results
Comparing Validity of Non-Invasive Hemoglobin Monitoring to Laboratory Results in Critically Ill Children
This is a prospective study to determine the accuracy of the Masimo Pronto Non-Invasive Hemoglobin Monitor and associated Rainbow® probes in the detection of hemoglobin concentration in critically ill children.
- Trial name
- NCT01750463
- Testing
- Masimo Pronto Rad 7 Non-Invasive hemoglobin monitor, Standard Laboratory Blood Draw and Hemoglobin Analysis
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of North Carolina, Chapel Hill
Sleep Disorders
Evaluation of WP200 With the Unified Probe (WP200U)
The prevalence of OSAS is estimated at 2% and 4% for adult women and men respectively, most of whom are undiagnosed and untreated.
- Trial name
- NCT01929447
- Where
- Israel
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Itamar-Medical, Israel
Hemophilia, Chronic Disease
Patient Reported Outcomes Burdens and Experiences - Phase 3
The PROBE Phase-3 study will collect data on patient reported outcomes, burdens, and experiences in patients living with hemophilia.
- Trial name
- PROBE-3 (NCT03549858)
- Testing
- Quality of life measure (survey)
- Where
- Canada
- Volunteers
- 1,000 people
- Sponsor
- McMaster University