Clinical trials: Procedural Pain Relief
Procedural Pain, Acute Pain
Breathing Toy for Pain Relief in Pediatric Venipuncture
This randomized controlled trial evaluated the effectiveness of a realistic breathing toy distraction intervention on procedural pain, physiological parameters, and parental anxiety during venipuncture in children aged 1-3 years…
- Conditions
- Procedural Pain, Acute Pain, Pediatric Pain
- Trial name
- BREATHE (NCT07430514)
- Testing
- Breathing Simulation Plush Toy Distraction During Pediatric Blood Collection
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Koç University
Pain, Premature Infant
Efficacy of Breast Milk Expressed and Sucrose in Procedural Pain in Preterm
The aim of this study is to assess the non-inferiority of non- pharmacological breast milk expressed versus oral sucrose in relief procedural pain of venipuncture in preterm neonates.
- Conditions
- Pain, Premature Infant, Human Milk, Breastfeeding
- Trial name
- LACTEET (NCT02133716)
- Testing
- expressed breast milk, sucrose 24% oral
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Pain Relief
Buzzy Distraction During Venipuncture
Venipuncture is one of the most common iatrogenic painful and stressful procedures performed on children. Interventions aimed at reducing the distress related to this experience are widely and strongly recommended.
- Trial name
- NCT02969902
- Testing
- Buzzy® device, Hand-held computer
- Volunteers
- 200 people
- Sponsor
- IRCCS Burlo Garofolo
Procedural Pain Relief
Needle Procedures Success Rate After Application of Ralydan vs EMLA in Children
Needle-related procedures are among the most common sources of pain and distress for children in the health care setting. More than 50% of children reported pain during these procedures.
- Trial name
- NCT02519660
- Testing
- Lidocaine/Tetracaine patch, Lidocaine/Prilocaine cream
- Where
- 3 sites in Italy
- Volunteers
- 339 people
- Sponsor
- IRCCS Burlo Garofolo
Procedural Pain, Procedural Anxiety
Efficacy of VR and Buzzy on Pain and Anxiety
The study was designed as a randomized controlled experimental research with the purpose of determining the effect of distraction by using external cold and vibration-Buzzy and VR on reducing procedural pain and anxiety in…
- Conditions
- Procedural Pain, Procedural Anxiety, Pain, Children, Only
- Trial name
- NCT05179291
- Testing
- Buzzy Group, Virtual Realitiy-VR Group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bandırma Onyedi Eylül University
Autoimmune Rheumatologic Disease, Immune Deficiency
Pilot Study of a New Device (Buzzy®) for Procedural Pain Relief During Needle-Related Procedures in Paediatric Patients
Needle-related procedures are the most important source of pain and anxiety in pediatric patients. Consequently, needle-phobia and anxiety are common in children with auto-immune disease and immune deficiency and may be barriers…
- Conditions
- Autoimmune Rheumatologic Disease, Immune Deficiency, Pain Due to Certain Specified Procedures, Child/Adolescent Problems
- Trial name
- NCT02771600
- Testing
- Buzzy, Topical anaesthetic cream
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- St. Justine's Hospital
Post Procedural Pain Management in Neonates
Comparison of Minimal Effective Dose of Sucrose for Pain Relief in Neonates After Minor Procedure
Type of Study: Randomized Controlled Trial Aim: To compare the effectiveness of two doses of sucrose solution for pain relief in neonates after minor procedures.
- Trial name
- NCT06446323
- Testing
- 0.2 ml dose of sucrose
- Where
- Pakistan
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College
Pain
Breast Milk vs Sucrose in Relieving Procedural Pain in Preterm Neonates During Blood Draw by Automated Heel Lance
Skin breaking procedure through an automated heel lancet for blood draws is a common painful procedure in the Neonatal Intensive care unit (NICU). Recurrent pain in preterm neonates is associated with long-term complications.
- Trial name
- NCT04898881
- Testing
- Breast Human Milk, 24 % Sucrose
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Wayne State University
Procedural Pain Relief, Fear Pain
Pharmacological and Nonpharmacological Methods for Children in Venipuncture Pain
This study aimed to examine the effect of EMLA cream, cold spray, and Buzzy applied during venipuncture on the pain and fear levels of children aged 7-12 years.
- Trial name
- NCT06901271
- Testing
- EMLA Cream, Buzzy, Cold spray
- Where
- Turkey (Türkiye)
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Aynur Aytekin Ozdemir
Retinopathy of Prematurity, Pain, Procedural
Clonidine as Pain Relief During ROP Eye Examinations
Preterm infants are at risk of developing ROP (retinopathy of prematurity), an eye condition that can cause blindness. Preterm infants born before gestation week (GA) 30 are therefor screened regularly with eye examinations.
- Conditions
- Retinopathy of Prematurity, Pain, Procedural, Premature Infant Disease
- Trial name
- cloROP (NCT04902859)
- Testing
- Clonidine Oral Liquid Product, Sterile water
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Örebro County
Pain Relief
Tablet Distraction for Pain Control During Venipuncture
Venipuncture is one of the painful procedures most frequently performed in children. Pain and distress management in children, during needle related procedures, is warranted.
- Trial name
- NCT02614391
- Testing
- Active distraction using a tablet, Passive distraction
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS Burlo Garofolo
Procedural Pain Relief, Virtual Reality
AI-Generated Video Distraction Via Virtual Reality for Fear and Pain During Pediatric Circumcision
This randomized controlled trial evaluated the effect of artificial intelligence-generated video distraction delivered via virtual reality on procedural fear and pain in children undergoing circumcision.
- Conditions
- Procedural Pain Relief, Virtual Reality, Fear, Child
- Trial name
- NCT07824427
- Testing
- AI-Generated Video Distraction via Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Pain Relief
Vibration and Cold for Pain Relief During Peripheral Intravenous Cannulation in Children With Intellectual Disability
Needle procedures are the most common and important source of pain and distress in children in the health care setting. Children with intellectual disability from any cause experience pain more frequently than healthy children.
- Trial name
- NCT02434731
- Testing
- Buzzy® device
- Where
- Italy
- Volunteers
- 71 people
- Sponsor
- IRCCS Burlo Garofolo