Clinical trials: Prognosis
Merkel Cell Carcinoma
SerUM Markers in MERkel Cell Carcinoma Patients: a Longitudinal moniTorIng Study for optiMization of European Guidelines
Merkel cell carcinoma (MCC) is a rare aggressive skin carcinoma. Approximately 80% of MCC are related to the Merkel Cell Polyomavirus (MCPyV). Although rates of relapse are high, the follow-up strategy lacks consensus.
- Trial name
- SUMMERTIME (NCT04705389)
- Testing
- Samples
- Where
- 10 sites in Austria, Finland and 8 more
- Volunteers
- 35 people
- Sponsor
- University Hospital, Tours
Colorectal Cancer
Does Administration of Antibiotics in Patients Undergoing Surgery for Colorectal Cancer Result in Less Complications and Better Prognosis?
The primary objectives of this randomized clinical trial are to evaluate if perioperative SDD can reduce clinical anastomotic leakage rate and its septic consequences as well as other infectious complications.
- Trial name
- SELECT (NCT01740947)
- Testing
- Selective decontamination of the digestive tract (SDD) (colistin sulfate, tobramycin, amphotericin B)
- Where
- 5 sites in Netherlands
- Volunteers
- 485 people
- Sponsor
- H. Jaap Bonjer, PhD
Dengue Fever
Laboratory Diagnosis and Prognosis of Severe Dengue
A study of dengue in children presenting to outpatient departments of 5 large hospitals in Ho Chi Minh City and Tien Giang province, Viet Nam.
- Trial name
- NCT01421732
- Where
- Vietnam
- Volunteers
- 8,100 people
- Sponsor
- Oxford University Clinical Research Unit, Vietnam
Leiden Factor V Deficiency,Preeclampsia, Doppler Examination
Prediction of Outcome in Severe Preeclampsia
this summary studied the predictive values of factor V Leiden mutation , doppler indices , placental pathology to unfavorable fetal and maternal outcomes
- Conditions
- Leiden Factor V Deficiency,Preeclampsia, Doppler Examination, Palental Pathology
- Trial name
- NCT03871764
- Testing
- blood sample , doppler of uterine vessel and placenta
- Volunteers
- 100 people
- Sponsor
- Cairo University
Hematological Malignancies
Tissue Microarray of Hematological Malignancies
The aim of the study is to create new tools for improving management of patients with hematological malignancies by combining extensive clinical data from patients newly diagnosed with hematological malignancies and innovative…
- Trial name
- HemaTMA (NCT04142372)
- Where
- Finland
- Volunteers
- 5,000 people
- Sponsor
- Tampere University Hospital
Autism Spectrum Disorder, Autistic Disorder
Risk Factors and Prognosis of Autism Spectrum Disorder
This case-control study with prospective follow-up aims to identify risk factors associated with autism spectrum disorder and to evaluate the prognosis of children with ASD attending Assiut University Children's Hospital.
- Conditions
- Autism Spectrum Disorder, Autistic Disorder, Child Development Disorders, Pervasive
- Trial name
- NCT07818460
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Assiut University
Renal Carcinoma, Serology
Serological Autoantibodies in Early Kidney Cancer Diagnosis and Prognosis: A Multicenter Study
This project aims to construct a multicenter retrospective study by retrospectively collecting clinical, serological, and pathological data from patients.
- Conditions
- Renal Carcinoma, Serology, Autoantibody
- Trial name
- NCT06917560
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Cerebral Palsy
Smartphone App for Analysis of General Movements in Young Infants
Analysis of spontaneous movements in young infants from video recordings is recommended as an early medical assessment tool for prediction of cerebral palsy in high-risk infants.
- Trial name
- NCT03409978
- Testing
- in-Motion app
- Where
- 3 sites in Belgium, Denmark and 1 more
- Volunteers
- 86 people
- Sponsor
- St. Olavs Hospital
Malignant Glioma
Post-Marketing Surveillance of Long-Term Observation of Gliadel Wafer-Investigation of Vital Prognosis in Patients With High Grade Glioma
The objective of this study is to determine the survival status of patients enrolled in study GLI01S (all-case observational study).
- Trial name
- NCT02300506
- Testing
- No intervention
- Where
- 2 sites in Japan
- Volunteers
- 507 people
- Sponsor
- Eisai Co., Ltd.
Anterior Cruciate Ligament Injuries
Relationship Between Anterior Tibial Subluxation and the Prognosis of Anterior Cruciate Ligament Reconstruction.
To identify the improvement of anterior tibial subluxation (ATS) and the relationship between ATS and patient reported outcome on pre- and postoperative anterior cruciate ligament-injured MRI images.
- Trial name
- NCT04944693
- Testing
- Different ATS values.
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital
Lung Cancer
Gemcitabine, Carboplatin or Paclitaxel Plus Radiation Therapy in Treating Patients With Stage IIIA or IIIB Non-Small Cell Lung Cancer
RATIONALE: Drugs used in chemotherapy, such as gemcitabine, carboplatin, and paclitaxel, work in different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00016315
- Testing
- carboplatin, gemcitabine hydrochloride, paclitaxel
- Where
- 19 sites in United States
- Volunteers
- 35 people
- Sponsor
- Radiation Therapy Oncology Group
Refractory Mycoplasma Pneumoniae Pneumonia
Combined Diagnostic Approach for Refractory Mycoplasma Pneumonia in Children
This study evaluates whether a combined approach using bronchoscopy, chest CT scoring, and monocyte subpopulation analysis can improve clinical outcomes for children with refractory Mycoplasma pneumoniae pneumonia (RMPP) when…
- Trial name
- NCT07064278
- Testing
- Bronchoscopy with Bronchoalveolar Lavage, Chest CT with Scoring, Monocyte Subpopulation Analysis
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Children's Hospital of Hebei Province
Lung Transplantation, Respiratory Failure
Prognosis of Lung Transplant Candidates
The purposes of the study are (1) to analyze the baseline patient characteristics cross-sectionally, (2) to analyze the prognosis and its predictive factors and (3) to examine the longitudinal clinical course in the lung…
- Trial name
- NCT00905463
- Testing
- Lung transplantation
- Where
- 4 sites in Japan
- Volunteers
- 272 people
- Sponsor
- Kyoto University, Graduate School of Medicine
Lymphoma
Clinical Application of Liquid Biopsy for Precise Diagnosis and Prognosis in Lymphoma
Lymphoma is a highly heterogeneous blood malignancy. It is very important to search for relative specific diagnostic markers that can detect related lymphoma in early stage for the treatment and long-term prognosis of the…
- Trial name
- NCT04062877
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Ge Zheng
Intracranial Germ Cell Tumor, Intracranial Germ Cell CNS Tumor, Childhood
Surveillance of Association of Immune Status and Prognosis of CNS Germ Cell Tumor Survivors
Platinum-based chemotherapy, alternating at 21-days intervals with cycles of ifosfamide, cisplatin, and etoposide (ICE) and subsequently received radiotherapy were considered as standard treatment for intracranial germ cell…
- Conditions
- Intracranial Germ Cell Tumor, Intracranial Germ Cell CNS Tumor, Childhood, Surgery
- Trial name
- NCT04909307
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Chengcheng Guo
Aortic Aneurysm and Dissection
Young Patient With Aortic Dissection or Aneurysm: A Prospective Observational Cohort Study
Aortic dissection or aneurysm is unusual in young patients, and frequently associated with unusual presentations. However studies about this area is scarce. Besides, the treatment option is not clare.
- Trial name
- NCT04431336
- Testing
- movement
- Volunteers
- 100 people
- Sponsor
- Chinese Medical Association
Ischemic Stroke, Large-Artery Atherosclerosis (Embolus/Thrombosis)
Study of Predictive Factors Related to Prognosis of Patients With Ischemic Stroke Due to Large-artery Atherosclerosis
This is a single-center prospective cohort study of predictive factors related to prognosis of ischemic stroke due to large-artery atherosclerosis.
- Trial name
- NCT04847752
- Testing
- carotid artery stenting, carotid endarterectomy, Aspirin
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Tongji Hospital
Ovarian Cancer
Impact of Different BRCA1/2 Gene Variants on Response to Therapy and Prognosis of Ovarian Cancer
Identify any significant differences in terms of drug response and survival between the different possible alterations in the BRCA1/2 genes, in order to stratify ovarian cancer patients with a view to increasingly personalised…
- Trial name
- NCT06775470
- Testing
- Patients must have been diagnosed with ovarian cancer and be BRCA positive, BRCA1 and BRCA2 positive, and be affected by Ovarian Cancer
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Congenital Heart Disease, Pediatric
Analysis of Risk Factors and Prognosis of Pediatric Patients After Operations for Congenital Heart Disease
This hospital-based retrospective study reviewed patients who underwent surgery for CHD between 2017 and 2020 and analyzed the clinical features and outcomes associated with airway anomalies.
- Trial name
- NCT06031831
- Testing
- airway anomalies
- Where
- Taiwan
- Volunteers
- 999 people
- Sponsor
- National Taiwan University Hospital
Hypertrophic Cardiomyopathy (HCM)
One-stop Evaluation of Hypertrophic Cardiomyopathy in Cardiac Magnetic Resonance
This is a multi-center, observational study aiming to establish a precision diagnosis scheme and multi-dimensional risk prediction models for Hypertrophic Cardiomyopathy (HCM). The study plans to enroll 10000 adult HCM patients.
- Trial name
- NCT07336290
- Volunteers
- 10,000 people
- Sponsor
- Minjie Lu